JPH07173193A - 生物学的活性ポリペプチド類 - Google Patents

生物学的活性ポリペプチド類

Info

Publication number
JPH07173193A
JPH07173193A JP6254765A JP25476594A JPH07173193A JP H07173193 A JPH07173193 A JP H07173193A JP 6254765 A JP6254765 A JP 6254765A JP 25476594 A JP25476594 A JP 25476594A JP H07173193 A JPH07173193 A JP H07173193A
Authority
JP
Japan
Prior art keywords
polypeptide
tgf
growth factor
phe
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6254765A
Other languages
English (en)
Japanese (ja)
Inventor
George J Todaro
ジョージ、ジョセフ、トダロ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPH07173193A publication Critical patent/JPH07173193A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP6254765A 1983-05-09 1994-09-22 生物学的活性ポリペプチド類 Pending JPH07173193A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49275183A 1983-05-09 1983-05-09
US492751 1983-05-09
US59813684A 1984-04-12 1984-04-12
US598136 1984-04-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP59091171A Division JPS6034997A (ja) 1983-05-09 1984-05-09 生物学的活性ポリペプチド類

Publications (1)

Publication Number Publication Date
JPH07173193A true JPH07173193A (ja) 1995-07-11

Family

ID=27050855

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6254765A Pending JPH07173193A (ja) 1983-05-09 1994-09-22 生物学的活性ポリペプチド類

Country Status (14)

Country Link
EP (1) EP0132021B1 (enExample)
JP (1) JPH07173193A (enExample)
AU (1) AU575049B2 (enExample)
CA (2) CA1341508C (enExample)
DE (1) DE3485219D1 (enExample)
DK (1) DK227384A (enExample)
ES (1) ES532286A0 (enExample)
FI (1) FI81365C (enExample)
GR (1) GR82078B (enExample)
IE (1) IE57724B1 (enExample)
IL (1) IL71702A (enExample)
NO (1) NO169348C (enExample)
NZ (1) NZ207983A (enExample)
PT (1) PT78571B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3587022T2 (de) * 1984-02-17 1993-06-17 Genentech Inc Menschlicher transformationswachstumsfaktor und vorlaeufer oder fragment hiervon, zellen, dna, vektoren und verfahren zu ihrer herstellung, zusammensetzungen und produkte, die diese enthalten, sowie davon abgeleitete antikoerper und diagnostizierverfahren.
AU5249786A (en) * 1985-01-29 1986-08-07 Oncogen Wound healing compositions
US4686283A (en) * 1985-04-16 1987-08-11 Syntex (U.S.A.) Inc. Analogs of transforming and epidermal growth factor fragments for therapy and diagnosis
NZ222168A (en) * 1986-10-20 1991-05-28 Oncogene Science Inc Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
US4931548A (en) * 1987-01-30 1990-06-05 Techne Corporation Heterodimer form of transforming growth factor-beta
AU1539188A (en) * 1987-05-04 1988-11-10 Bristol-Myers Squibb Company TGF-B2 and novel compositions having anti-neoplastic activity
CA2070393A1 (en) * 1989-10-18 1991-04-19 Charles M. Cohen Biosynthetic constructs of tgf-beta
US6040431A (en) 1995-06-07 2000-03-21 Stryker Corporation Single chain analogs of the TGF-β superfamily (morphons)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6058960B2 (ja) * 1978-10-09 1985-12-23 サントリー株式会社 ウィルスの検出，定量剤
DE3382562D1 (de) * 1982-09-24 1992-06-25 Us Health Wiederherstellung von gewebe bei tieren.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J.BIOL.CHEM.257 24=1982 *

Also Published As

Publication number Publication date
PT78571B (en) 1986-06-26
ES8600518A1 (es) 1985-09-16
FI81365B (fi) 1990-06-29
AU2751384A (en) 1984-11-15
IE57724B1 (en) 1993-03-24
PT78571A (en) 1984-06-01
FI841649A0 (fi) 1984-04-26
CA1341508C (en) 2006-06-13
AU575049B2 (en) 1988-07-21
NO169348C (no) 1992-06-10
IL71702A (en) 1988-01-31
EP0132021A1 (en) 1985-01-23
IE840999L (en) 1984-11-09
FI841649L (fi) 1984-11-10
GR82078B (enExample) 1984-12-13
DE3485219D1 (de) 1991-12-05
FI81365C (fi) 1990-10-10
NO841827L (no) 1984-11-12
NZ207983A (en) 1991-09-25
CA1341535C (en) 2007-07-24
ES532286A0 (es) 1985-09-16
NO169348B (no) 1992-03-02
IL71702A0 (en) 1984-07-31
EP0132021B1 (en) 1991-10-30
DK227384D0 (da) 1984-05-08
DK227384A (da) 1984-11-10

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