JPH06511483A - インドール類 - Google Patents

インドール類

Info

Publication number
JPH06511483A
JPH06511483A JP5502592A JP50259293A JPH06511483A JP H06511483 A JPH06511483 A JP H06511483A JP 5502592 A JP5502592 A JP 5502592A JP 50259293 A JP50259293 A JP 50259293A JP H06511483 A JPH06511483 A JP H06511483A
Authority
JP
Japan
Prior art keywords
formula
alkyl
compound represented
aryl
represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5502592A
Other languages
English (en)
Japanese (ja)
Inventor
ブラツグ，ジユリアン
クーパー，ケルビン
スパーゴ，ピーター・ライオネル
Original Assignee
フアイザー・インコーポレイテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by フアイザー・インコーポレイテツド filed Critical フアイザー・インコーポレイテツド
Publication of JPH06511483A publication Critical patent/JPH06511483A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP5502592A 1991-07-24 1992-07-20 インドール類 Pending JPH06511483A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919115951A GB9115951D0 (en) 1991-07-24 1991-07-24 Indoles
GB9115951,7 1991-07-24
PCT/EP1992/001626 WO1993002051A1 (en) 1991-07-24 1992-07-20 Indoles

Publications (1)

Publication Number Publication Date
JPH06511483A true JPH06511483A (ja) 1994-12-22

Family

ID=10698873

Family Applications (2)

Application Number Title Priority Date Filing Date
JP5502592A Pending JPH06511483A (ja) 1991-07-24 1992-07-20 インドール類
JP5502591A Pending JPH06509336A (ja) 1991-07-24 1992-07-20 インドール類

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP5502591A Pending JPH06509336A (ja) 1991-07-24 1992-07-20 インドール類

Country Status (20)

Country Link
EP (2) EP0598750A1 (enExample)
JP (2) JPH06511483A (enExample)
CN (2) CN1068816A (enExample)
AU (2) AU2327192A (enExample)
BR (1) BR9206306A (enExample)
CA (2) CA2112689A1 (enExample)
CZ (1) CZ13694A3 (enExample)
FI (2) FI940311A0 (enExample)
GB (1) GB9115951D0 (enExample)
HU (1) HU9400199D0 (enExample)
IE (2) IE922387A1 (enExample)
IL (2) IL102545A0 (enExample)
MX (1) MX9204342A (enExample)
NO (1) NO940237D0 (enExample)
NZ (1) NZ243687A (enExample)
PT (2) PT100717A (enExample)
SK (1) SK8494A3 (enExample)
TW (1) TW223060B (enExample)
WO (2) WO1993002051A1 (enExample)
ZA (2) ZA925546B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009515935A (ja) * 2005-11-18 2009-04-16 サノフイ−アベンテイス ３−アシルインドール誘導体、これらの調製および治療的使用

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9204024D0 (en) * 1992-02-25 1992-04-08 Fujisawa Pharmaceutical Co Indole derivatives
GB9302577D0 (en) * 1993-02-10 1993-03-24 Fujisawa Pharmaceutical Co Indole derivatives
WO1994022821A1 (en) * 1993-04-05 1994-10-13 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives as testosterone 5 alpha-reductase inhibitors
GB9310092D0 (en) * 1993-05-17 1993-06-30 Fujisawa Pharmaceutical Co Indole derivatives
GB9317096D0 (en) * 1993-08-17 1993-09-29 Pfizer Ltd Indoles
PT753511E (pt) * 1994-03-30 2001-11-30 Zeria Pharm Co Ltd Derivados de acido 4-indol-1-butirico, sua preparacao e utilizacao como inibidores dos receptores alfa-1-adrenergicos e das 5-alfa-redutases da testosterona
GB9409583D0 (en) * 1994-05-13 1994-07-06 Pfizer Ltd Indoles
US5543417A (en) * 1994-10-21 1996-08-06 Merck & Co., Inc. Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase inhibitors with anti-bacterial, keratolytic, or anti-inflammatory agents
CN1200704C (zh) 1997-05-14 2005-05-11 阿特罗吉尼克斯公司 普罗布考单酯在治疗心血管疾病和炎性疾病中的应用
US6670398B2 (en) 1997-05-14 2003-12-30 Atherogenics, Inc. Compounds and methods for treating transplant rejection
US7417063B2 (en) 2004-04-13 2008-08-26 Bristol-Myers Squibb Company Bicyclic heterocycles useful as serine protease inhibitors
PE20090159A1 (es) 2007-03-08 2009-02-21 Plexxikon Inc COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
EP2139320A4 (en) 2007-03-26 2010-09-08 Salutria Pharmaceuticals Llc METHODS AND COMPOSITIONS OF PROBUCOL DERIVATIVES FOR THE TREATMENT OF DIABETES
US10703969B2 (en) * 2016-09-27 2020-07-07 Kaohsiung Medical University Detection method for quaternary ammonium compound having γ-carboxyl group

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9011335D0 (en) * 1990-05-21 1990-07-11 Fujisawa Pharmaceutical Co Indolebutyric acid derivatives and process for preparation thereof
WO1993005020A1 (en) * 1991-09-06 1993-03-18 Merck & Co., Inc. Indoles as inhibitors of hiv reverse transcriptase

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009515935A (ja) * 2005-11-18 2009-04-16 サノフイ−アベンテイス ３−アシルインドール誘導体、これらの調製および治療的使用

Also Published As

Publication number Publication date
IE922387A1 (en) 1993-01-27
MX9204342A (es) 1994-03-31
CN1068816A (zh) 1993-02-10
CA2112689A1 (en) 1993-02-04
GB9115951D0 (en) 1991-09-11
IL102545A0 (en) 1993-01-14
ZA925546B (en) 1994-01-24
FI940310A7 (fi) 1994-01-21
AU2327092A (en) 1993-02-23
SK8494A3 (en) 1994-11-09
HU9400199D0 (en) 1994-05-30
PT100718A (pt) 1993-08-31
IE922386A1 (en) 1993-01-27
FI940311A7 (fi) 1994-01-21
NO940237L (no) 1994-01-24
FI940310A0 (fi) 1994-01-21
JPH06509336A (ja) 1994-10-20
WO1993002051A1 (en) 1993-02-04
AU2327192A (en) 1993-02-23
FI940311A0 (fi) 1994-01-21
BR9206306A (pt) 1994-11-08
EP0598750A1 (en) 1994-06-01
NO940237D0 (no) 1994-01-24
EP0598754A1 (en) 1994-06-01
IL102544A0 (en) 1993-01-14
NZ243687A (en) 1994-12-22
AU655662B2 (en) 1995-01-05
ZA925547B (en) 1994-01-24
TW223060B (enExample) 1994-05-01
WO1993002050A1 (en) 1993-02-04
PT100717A (pt) 1993-08-31
CA2112678A1 (en) 1993-02-04
CZ13694A3 (en) 1994-07-13
CN1068817A (zh) 1993-02-10

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