JPH05503635A - 細胞マスおよび／または発酵産物を無菌条件下で生産する方法、およびこの方法を実施する装置 - Google Patents
細胞マスおよび／または発酵産物を無菌条件下で生産する方法、およびこの方法を実施する装置Info
- Publication number
- JPH05503635A JPH05503635A JP3518666A JP51866691A JPH05503635A JP H05503635 A JPH05503635 A JP H05503635A JP 3518666 A JP3518666 A JP 3518666A JP 51866691 A JP51866691 A JP 51866691A JP H05503635 A JPH05503635 A JP H05503635A
- Authority
- JP
- Japan
- Prior art keywords
- medium
- cell
- fermenter
- culture
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 241000588748 Klebsiella Species 0.000 description 1
- 241000589248 Legionella Species 0.000 description 1
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- 241000192001 Pediococcus Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
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- BGLAPYTXCULTEW-UHFFFAOYSA-A dialuminum;octasodium;hydrogen phosphate;tetraphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Al+3].[Al+3].OP([O-])([O-])=O.OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O BGLAPYTXCULTEW-UHFFFAOYSA-A 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
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- CJNBYAVZURUTKZ-UHFFFAOYSA-N hafnium(IV) oxide Inorganic materials O=[Hf]=O CJNBYAVZURUTKZ-UHFFFAOYSA-N 0.000 description 1
- 238000009775 high-speed stirring Methods 0.000 description 1
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- KKCBUQHMOMHUOY-UHFFFAOYSA-N sodium oxide Chemical compound [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 1
- 229910001948 sodium oxide Inorganic materials 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/813—Continuous fermentation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4037325.8 | 1990-11-23 | ||
| DE4037325A DE4037325A1 (de) | 1990-11-23 | 1990-11-23 | Verfahren zur erzeugung von zellmasse und/oder fermentierungsprodukten unter sterilen bedingungen sowie vorrichtung zur durchfuehrung des verfahrens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH05503635A true JPH05503635A (ja) | 1993-06-17 |
Family
ID=6418808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3518666A Pending JPH05503635A (ja) | 1990-11-23 | 1991-11-21 | 細胞マスおよび／または発酵産物を無菌条件下で生産する方法、およびこの方法を実施する装置 |
Country Status (17)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705373A (en) * | 1993-12-24 | 1998-01-06 | Takeda Chemical Industries, Ltd. | Production of 2-keto-L-gulonic acid using pseudogluconobacter saccharoketogenes with recycling |
| JP2007501613A (ja) * | 2003-08-07 | 2007-02-01 | エヌシーエイチ コーポレイション | バイオマス発生器 |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE9419230U1 (de) * | 1994-12-02 | 1995-03-09 | Forschungszentrum Jülich GmbH, 52428 Jülich | Anordnung für fed-batch-Prozeßuntersuchungen in einer Schüttelkolbenserie |
| FI100338B (fi) * | 1995-07-18 | 1997-11-14 | Danisco Sugar Finland Oy | Menetelmä puhtaan maitohapon valmistamiseksi |
| DE19718608A1 (de) * | 1997-05-02 | 1998-11-05 | Ireks Gmbh | Verfahren zur Herstellung von Milchsäure |
| US7879593B2 (en) | 1999-12-16 | 2011-02-01 | Whiteman G Robert | Fermentation systems, methods and apparatus |
| US9969633B2 (en) * | 1999-12-16 | 2018-05-15 | Robert Whiteman | Systems and methods for treating oil, fat and grease in collection systems |
| US20020117445A1 (en) * | 1999-12-16 | 2002-08-29 | Whiteman G. Robert | Fermentation systems, methods, and apparatus |
| DE60124780T2 (de) * | 2000-12-20 | 2007-10-11 | Bayer Pharmaceuticals Corp., West Haven | Vorrichtung und verfahren zur serienvermehrung von säugerzellen zum animpfen |
| JP3958089B2 (ja) * | 2002-03-26 | 2007-08-15 | 有限会社新世紀発酵研究所 | 嫌気性菌の連続培養法 |
| US7435581B2 (en) * | 2003-11-26 | 2008-10-14 | Broadley-James Corporation | Integrated bio-reactor monitor and control system |
| US7635586B2 (en) | 2003-11-26 | 2009-12-22 | Broadley-James Corporation | Integrated bio-reactor monitor and control system |
| US20080305213A1 (en) * | 2007-06-11 | 2008-12-11 | Kerry Group Services International, Ltd. | Method and composition for preparing cured meat products |
| EP2398887A1 (en) * | 2009-02-18 | 2011-12-28 | Universiti Sains Malaysia | A solid state fermentation (ssf) system |
| US8961893B2 (en) | 2009-07-07 | 2015-02-24 | Nch Corporation | Automated chemical diluter system having disposable components |
| US8551762B2 (en) | 2009-07-07 | 2013-10-08 | Nch Corporation | System and apparatus for feeding, solubilizing, growing and discharging a biological material |
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- 1990-11-23 DE DE4037325A patent/DE4037325A1/de active Granted
-
1991
- 1991-10-07 DK DK91117048.8T patent/DK0487867T3/da active
- 1991-10-07 ES ES91117048T patent/ES2090199T3/es not_active Expired - Lifetime
- 1991-10-07 AT AT91117048T patent/ATE138684T1/de not_active IP Right Cessation
- 1991-10-07 EP EP91117048A patent/EP0487867B1/de not_active Expired - Lifetime
- 1991-10-07 DE DE59107860T patent/DE59107860D1/de not_active Expired - Lifetime
- 1991-11-21 WO PCT/EP1991/002189 patent/WO1992009683A1/de active IP Right Grant
- 1991-11-21 KR KR1019920701770A patent/KR920703786A/ko not_active Withdrawn
- 1991-11-21 HU HU9202189A patent/HUT65380A/hu unknown
- 1991-11-21 BR BR919106024A patent/BR9106024A/pt not_active Application Discontinuation
- 1991-11-21 US US07/795,899 patent/US5981260A/en not_active Expired - Lifetime
- 1991-11-21 AU AU89466/91A patent/AU672745B2/en not_active Ceased
- 1991-11-21 JP JP3518666A patent/JPH05503635A/ja active Pending
- 1991-11-21 CZ CS921883A patent/CZ283799B6/cs unknown
- 1991-11-21 CA CA002074466A patent/CA2074466C/en not_active Expired - Lifetime
-
1992
- 1992-05-13 FI FI922172A patent/FI101083B/fi active
- 1992-07-20 BG BG96651A patent/BG61039B1/bg unknown
- 1992-07-21 NO NO922887A patent/NO303230B1/no not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705373A (en) * | 1993-12-24 | 1998-01-06 | Takeda Chemical Industries, Ltd. | Production of 2-keto-L-gulonic acid using pseudogluconobacter saccharoketogenes with recycling |
| JP2007501613A (ja) * | 2003-08-07 | 2007-02-01 | エヌシーエイチ コーポレイション | バイオマス発生器 |
Also Published As
| Publication number | Publication date |
|---|---|
| BG96651A (bg) | 1993-12-24 |
| BG61039B1 (bg) | 1996-09-30 |
| ATE138684T1 (de) | 1996-06-15 |
| ES2090199T3 (es) | 1996-10-16 |
| FI922172A7 (fi) | 1992-05-24 |
| AU672745B2 (en) | 1996-10-17 |
| EP0487867B1 (de) | 1996-05-29 |
| US5981260A (en) | 1999-11-09 |
| CA2074466A1 (en) | 1992-05-24 |
| CA2074466C (en) | 2007-07-03 |
| DE4037325C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-08-19 |
| FI101083B (fi) | 1998-04-15 |
| WO1992009683A1 (de) | 1992-06-11 |
| AU8946691A (en) | 1992-06-25 |
| EP0487867A1 (de) | 1992-06-03 |
| NO922887L (no) | 1992-09-11 |
| FI922172A0 (fi) | 1992-05-13 |
| DE59107860D1 (de) | 1996-07-04 |
| BR9106024A (pt) | 1993-03-02 |
| HUT65380A (en) | 1994-05-02 |
| CS188392A3 (en) | 1992-12-16 |
| NO303230B1 (no) | 1998-06-15 |
| NO922887D0 (no) | 1992-07-21 |
| HU9202189D0 (en) | 1992-12-28 |
| CZ283799B6 (cs) | 1998-06-17 |
| KR920703786A (ko) | 1992-12-18 |
| DK0487867T3 (da) | 1996-10-07 |
| DE4037325A1 (de) | 1992-05-27 |
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