JPH05294995A - 抗菌性反転ペプチド、抗菌性オリゴペプチド及び他の抗菌性組成物、及びそれらの製造法ならびにそれらの使用法 - Google Patents

抗菌性反転ペプチド、抗菌性オリゴペプチド及び他の抗菌性組成物、及びそれらの製造法ならびにそれらの使用法

Info

Publication number
JPH05294995A
JPH05294995A JP4059848A JP5984892A JPH05294995A JP H05294995 A JPH05294995 A JP H05294995A JP 4059848 A JP4059848 A JP 4059848A JP 5984892 A JP5984892 A JP 5984892A JP H05294995 A JPH05294995 A JP H05294995A
Authority
JP
Japan
Prior art keywords
xaa
peptide
seq
amino acid
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4059848A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05294995A6 (ja
Inventor
Claudio Mapelli
メイピリィ クラウディオ
Catherine Dugas De Robertis
ダガス デ ロバーツ キャサリン
Geraldine Frances Stahl
フランシス スタール ゲラルディン
Newell Fred Bascomb
フレッド バスコム ニューエル
Michael Dennis Swerdloff
デニス スウェドロフ マイケル
Jon Ira Williams
アイラ ウィリアムス ジョン
Nicholas Paul Everett
ポール エバレット ニコラス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Guido Donegani SpA
Original Assignee
Istituto Guido Donegani SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Guido Donegani SpA filed Critical Istituto Guido Donegani SpA
Publication of JPH05294995A publication Critical patent/JPH05294995A/ja
Publication of JPH05294995A6 publication Critical patent/JPH05294995A6/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8281—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for bacterial resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP4059848A 1991-02-01 1992-01-31 抗菌性反転ペプチド、抗菌性オリゴペプチド及び他の抗菌性組成物、及びそれらの製造法ならびにそれらの使用法 Pending JPH05294995A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64978491A 1991-02-01 1991-02-01
US07/649784 1991-02-01

Publications (2)

Publication Number Publication Date
JPH05294995A true JPH05294995A (ja) 1993-11-09
JPH05294995A6 JPH05294995A6 (ja) 2004-11-25

Family

ID=24606221

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4059848A Pending JPH05294995A (ja) 1991-02-01 1992-01-31 抗菌性反転ペプチド、抗菌性オリゴペプチド及び他の抗菌性組成物、及びそれらの製造法ならびにそれらの使用法

Country Status (5)

Country Link
US (1) US5519115A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0497366A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH05294995A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU648140B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2060455C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017021014A (ja) * 2012-02-07 2017-01-26 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー 基板、ペプチドアレイ、および方法
JP2018507259A (ja) * 2015-02-22 2018-03-15 オムニクス メディカル リミテッド 抗微生物ペプチド
US10006909B2 (en) 2012-09-28 2018-06-26 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
US10816553B2 (en) 2013-02-15 2020-10-27 Vibrant Holdings, Llc Methods and compositions for amplified electrochemiluminescence detection
US11168365B2 (en) 2017-05-26 2021-11-09 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
US12319712B2 (en) 2018-05-09 2025-06-03 Vibrant Holdings, Llc Methods of synthesizing a polynucleotide array using photoactivated agents

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646119A (en) * 1991-11-01 1997-07-08 Periodontix, Inc. D-amino acid histatin-based peptides as anti-fungal and anti-bacterial agents
US5885965A (en) * 1991-11-01 1999-03-23 Periodontix, Inc. Anti-fungal D-amino acid histatin-based peptides
GB9127250D0 (en) * 1991-12-23 1992-02-19 Unilever Plc Modification
HUT71860A (en) * 1992-08-27 1996-02-28 Deakin Res Ltd Retro-, inverso-, and retro-inverso synthetic peptide analogues
US5607914A (en) * 1993-01-13 1997-03-04 Pioneer Hi-Bred International, Inc. Synthetic antimicrobial peptides
US5580852A (en) * 1993-12-17 1996-12-03 Pioneer Hi-Bred International, Inc. Derivatives of tachyplesin having inhibitory activity towards plant pathogenic fungi
FR2717081B1 (fr) 1994-03-14 1996-06-21 Centre Nat Rech Scient Rétropeptides, anticorps dirigés contre ces derniers, et leurs utilisations pour la vaccination et le diagnostic in vitro.
AT403167B (de) * 1994-11-14 1997-11-25 Immuno Ag Selektion und expression von fremdproteinen mittels eines selektions-amplifikations-systems
US5994067A (en) * 1995-11-14 1999-11-30 The United States Of America As Represented By The Secretary Of The Army Method and kit for rapid detection of toxins and bacteria
US6750381B2 (en) * 1996-03-25 2004-06-15 National Institute Of Agrobiological Sciences Pathogen-resistant plants transformed with a DNA encoding sarcotoxin 1A linked to a signal peptide and a method for production thereof
GB9725556D0 (en) * 1997-12-03 1998-02-04 Ciba Geigy Ag Organic compounds
US6545140B1 (en) * 1998-07-13 2003-04-08 University Of Georgia Research Foundation, Inc. DNA encoding an avian beta-defensin and uses thereof
BR9914922A (pt) * 1998-10-30 2001-07-10 Interlink Biotechnologies Llc Métodos para reduzir a extensão de degradação de protease de uma proteìna aplicada a ou produzida por uma planta, para inibir o crescimento de um patógeno vegetal e para produzir uma planta, peptìdeo, molécula de ácido nucleico, segmento de ácido nucleico, construção de ácido nucleico, planta transgênica, semente, célula vegetal, e, composição para o uso na proteção de um peptìdeo, polipeptìdeo ou proteìna da degradação da protease.
AU772335B2 (en) * 1998-10-30 2004-04-22 Interlink Biotechnologies Llc Peptides with enhanced stability to protease degradation
EP1163352A1 (en) * 1999-03-17 2001-12-19 University Of Victoria Innovation And Development Corporation Transgenic plants that are resistant to a broad spectrum of pathogens
US6835868B1 (en) 1999-03-17 2004-12-28 University Of Victoria Innovation And Development Corporation Transgenic plants expressing dermaseptin peptides providing broad spectrum resistance to pathogens
CA2379388C (en) * 1999-07-13 2012-05-29 George N. Cox, Iii Immunoglobulin fusion proteins
EP1174027A1 (en) * 2000-07-17 2002-01-23 HOM Consultancy B.V. Uses of antimicrobial peptides
JP3757268B2 (ja) * 2001-08-22 2006-03-22 独立行政法人農業・生物系特定産業技術研究機構 ペプチドとキレート剤を含む殺菌性組成物
CA2463908A1 (en) * 2001-10-18 2003-04-24 Bristol-Myers Squibb Company Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
DK1590458T3 (da) 2003-02-06 2013-02-04 Univ Belfast Bradykinin B2-receptorantagonistpeptid fra amfibiehud
US8338339B2 (en) * 2003-12-15 2012-12-25 The United States Of America As Represented By The Secretary Of Agriculture Process for inhibition of proteolytic activity during the ensiling of forages
WO2006062776A2 (en) * 2004-11-29 2006-06-15 The Regents Of The University Of California Hydroxyapatite-binding peptides for bone growth and inhibition
WO2006063055A2 (en) * 2004-12-06 2006-06-15 Bolder Biotechnology, Inc. Enzyme conjugates for use as detoxifying agents
US20070231833A1 (en) * 2005-05-23 2007-10-04 Arcidiacono Steven M Labeled antimicrobial peptides and method of using the same to detect microorganisms of interest
GB0611405D0 (en) 2006-06-09 2006-07-19 Univ Belfast FKBP-L: A novel inhibitor of angiogenesis
WO2008019368A2 (en) * 2006-08-07 2008-02-14 Teva Biopharmaceuticals Usa, Inc. Albumin-insulin fusion proteins
KR20090105913A (ko) 2006-11-02 2009-10-07 다니엘 제이 카폰 이동 부분을 갖는 하이브리드 면역글로불린
EP2755693A4 (en) 2011-09-12 2015-05-20 Moderna Therapeutics Inc MANIPULATED NUCLEIC ACIDS AND METHOD OF APPLICATION THEREFOR
WO2013151670A2 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of nuclear proteins
JP2015518705A (ja) 2012-04-02 2015-07-06 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ヒト疾患に関連する生物製剤およびタンパク質の産生のための修飾ポリヌクレオチド
CN102703457A (zh) * 2012-05-18 2012-10-03 中国农业科学院兰州兽医研究所 一种抗菌肽基因的制备及表达方法
MX373109B (es) * 2013-04-24 2020-03-25 Centro De Investig Y De Estudios Avanzados Del I P N Métodos para obtener plantas genéticamente modificadas resistentes a bacterias fitopatógenas que crecen en sus tejidos vasculares.
DE102013104897A1 (de) * 2013-05-13 2014-11-13 Gelita Ag Wirkstoff zur Behandlung von Sarkopenie
CN104738073A (zh) * 2013-12-26 2015-07-01 王宝燕 一种含蛙皮素的农药组合物
US11168131B2 (en) 2015-11-10 2021-11-09 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
SI3464336T1 (sl) 2016-06-01 2022-06-30 Athira Pharma, Inc. Spojine
EP3512887B1 (en) 2016-09-15 2024-07-31 Acceleron Pharma Inc. A fusion protein for use in treating anemia comprising twsg and fc
CA3049449A1 (en) 2017-01-18 2018-07-26 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
KR20240085798A (ko) 2020-04-03 2024-06-17 비스테라, 인크. 항체 분자-약물 접합체 및 이의 용도
US12116387B2 (en) * 2021-09-14 2024-10-15 The Trustees Of The University Of Pennsylvania Antimicrobial peptides
AU2024226512A1 (en) * 2023-02-23 2025-08-14 Micropep Technologies S.A. Antifungal peptides to control plant pathogens
CN116874562A (zh) * 2023-07-28 2023-10-13 兰州大学 以Rn为转角的具有KW重复序列的中心对称β-发卡型抗菌肽及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3850107T2 (de) * 1987-03-04 1995-02-23 The United States Of America, Represented By The Secretary, U.S. Department Of Commerce, Springfield, Va. Neue synthetische bioaktive verbindungen und verfahren zur herstellung bioaktiver wirkungen.
ATE127838T1 (de) * 1987-07-06 1995-09-15 Univ Louisiana State Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden.
US4880779A (en) * 1987-07-31 1989-11-14 Research Corporation Technologies, Inc. Method of prevention or treatment of AIDS by inhibition of human immunodeficiency virus
AU2802989A (en) * 1987-11-02 1989-06-01 Louisiana State University Agricultural And Mechanical College Plants genetically enhanced for disease resistance
DK8189A (da) * 1988-01-12 1989-07-13 Bunge Australia Antigen-antistof-konjugater, deres fremstilling og anvendelse
WO1989011290A1 (en) * 1988-05-27 1989-11-30 Magainin Sciences, Inc. Amphiphilic peptides and use thereof
US5185147A (en) * 1988-08-19 1993-02-09 Cellular Products, Inc. Short polypeptide sequences useful in the production and detection of antibodies against human immunodeficiency virus
DE68916261T2 (de) * 1988-10-21 1994-09-22 Philadelphia Children Hospital Zusammensetzung und behandelung mittels biologisch aktiven peptiden und bestimmten anionen.
US5217956A (en) * 1988-10-21 1993-06-08 The Children's Hospital Of Philadelphia Composition and treatment with biologically active peptides and certain anions
US5254537A (en) * 1989-01-30 1993-10-19 The Children's Hospital Of Pennsylvania Composition and treatment with peptide combinations
CA2007913A1 (en) * 1989-01-30 1990-07-30 Michael Zasloff Composition and treatment with peptide combinations
EP0425616A4 (en) * 1989-04-11 1991-11-27 Calgene, Inc. Use of animal-derived anti-microbial peptides for control of plant pathogens
US5254535A (en) * 1989-04-17 1993-10-19 The Children's Hospital Of Pennsylvania Composition and treatment with biologically active peptides and antibiotic
WO1991000869A1 (en) * 1989-07-07 1991-01-24 Scripps Clinic And Research Foundation Substitution analogues of magainin peptides
US5045531A (en) * 1989-12-18 1991-09-03 Magainin Sciences Inc. Wound treatment employing biologically active ion channel forming peptides and proteins
US5221664A (en) * 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
US5208220A (en) * 1990-06-27 1993-05-04 Magainin Pharmaceuticals, Inc. Composition and treatment with biologically active peptides and antibiotics which inhibit DNA gyrase

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11565231B2 (en) 2012-02-07 2023-01-31 Vibrant Holdings, Llc Substrates, peptide arrays, and methods
JP2017021014A (ja) * 2012-02-07 2017-01-26 ヴィブラント ホールディングス リミテッド ライアビリティ カンパニー 基板、ペプチドアレイ、および方法
US10486129B2 (en) 2012-02-07 2019-11-26 Vibrant Holdings, Llc Substrates, peptide arrays, and methods
US11815512B2 (en) 2012-09-28 2023-11-14 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10006909B2 (en) 2012-09-28 2018-06-26 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10175234B2 (en) 2012-09-28 2019-01-08 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10746732B2 (en) 2012-09-28 2020-08-18 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US11674956B2 (en) 2012-09-28 2023-06-13 Vibrant Holdings, Llc Methods, systems, and arrays for biomolecular analysis
US10286376B2 (en) 2012-11-14 2019-05-14 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
US10799845B2 (en) 2012-11-14 2020-10-13 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
US12251674B2 (en) 2012-11-14 2025-03-18 Vibrant Holdings, Llc Substrates, systems, and methods for array synthesis and biomolecular analysis
US10816553B2 (en) 2013-02-15 2020-10-27 Vibrant Holdings, Llc Methods and compositions for amplified electrochemiluminescence detection
JP2018507259A (ja) * 2015-02-22 2018-03-15 オムニクス メディカル リミテッド 抗微生物ペプチド
US11168365B2 (en) 2017-05-26 2021-11-09 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
US12152279B2 (en) 2017-05-26 2024-11-26 Vibrant Holdings, Llc Photoactive compounds and methods for biomolecule detection and sequencing
US12319712B2 (en) 2018-05-09 2025-06-03 Vibrant Holdings, Llc Methods of synthesizing a polynucleotide array using photoactivated agents

Also Published As

Publication number Publication date
AU1065092A (en) 1992-08-06
EP0497366A2 (en) 1992-08-05
AU648140B2 (en) 1994-04-14
EP0919566A2 (en) 1999-06-02
US5519115A (en) 1996-05-21
EP0497366A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-02-09
CA2060455C (en) 2007-07-10
EP0919566A3 (en) 1999-12-01
CA2060455A1 (en) 1992-08-02

Similar Documents

Publication Publication Date Title
JPH05294995A (ja) 抗菌性反転ペプチド、抗菌性オリゴペプチド及び他の抗菌性組成物、及びそれらの製造法ならびにそれらの使用法
JPH05294995A6 (ja) 抗菌性反転ペプチド、抗菌性オリゴペプチド及び他の抗菌性組成物、及びそれらの製造法ならびにそれらの使用法
Casteels et al. Apidaecins: antibacterial peptides from honeybees.
US8686224B2 (en) Plant defense signal peptides
Jaynes et al. Increasing bacterial disease resistance in plants utilizing antibacterial genes from insects
Nadal et al. Constitutive expression of transgenes encoding derivatives of the synthetic antimicrobial peptide BP100: impact on rice host plant fitness
US5424395A (en) Antimicrobial peptides active against plant pathogens
EP1006785B1 (en) Antimicrobial proteins
AU779466B2 (en) Synthetic peptides
US20130219532A1 (en) Peptides with antifungal activities
HU220115B (hu) Antipatogén peptidek, ezeket tartalmazó készítmények, eljárás növények védelmére és a peptideket kódoló szekvenciák
JP2002530274A (ja) プロテアーゼ分解に対する安定性の高いペプチド
US20080032924A1 (en) Antifungal Peptides
CA2110403A1 (en) Biocidal proteins
JP2003507009A (ja) タンパク質およびペプチド
CN102260348A (zh) 蝶蛹金小蜂毒液丝氨酸蛋白酶抑制剂Pp-PI多肽及应用
Montesinos Barreda Rice seeds as biofactories of the production of antimicrobial peptides
JP2005281291A (ja) 新規な抗菌性ペプチド、それを産生するための組換え体植物及び該抗菌性ペプチドの製造方法
AU2012201612A1 (en) Antifungal peptides
AU2005215825A1 (en) Antifungal peptides
MXPA01004316A (en) Peptides with enhanced stability to protease degradation

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20040109

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20040519

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 19930311

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20040519

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20051017

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20060117

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20060120

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20060626