JPH0516438B2 - - Google Patents

Info

Publication number
JPH0516438B2
JPH0516438B2 JP60076777A JP7677785A JPH0516438B2 JP H0516438 B2 JPH0516438 B2 JP H0516438B2 JP 60076777 A JP60076777 A JP 60076777A JP 7677785 A JP7677785 A JP 7677785A JP H0516438 B2 JPH0516438 B2 JP H0516438B2
Authority
JP
Japan
Prior art keywords
formula
obermycin
chloroform
substituent represented
strain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60076777A
Other languages
English (en)
Japanese (ja)
Other versions
JPS61236792A (ja
Inventor
Akihiro Yoshimoto
Osamu Shiromichi
Yoshio Watanabe
Tomoyuki Ishikura
Tsutomu Sawa
Tomio Takeuchi
Hamao Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MERUSHAN KK
Original Assignee
MERUSHAN KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MERUSHAN KK filed Critical MERUSHAN KK
Priority to JP60076777A priority Critical patent/JPS61236792A/ja
Priority to US06/849,229 priority patent/US4734493A/en
Priority to EP86104931A priority patent/EP0203329B1/en
Priority to DE8686104931T priority patent/DE3665304D1/de
Publication of JPS61236792A publication Critical patent/JPS61236792A/ja
Publication of JPH0516438B2 publication Critical patent/JPH0516438B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP60076777A 1985-04-12 1985-04-12 新規アントラサイクリン抗生物質 Granted JPS61236792A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP60076777A JPS61236792A (ja) 1985-04-12 1985-04-12 新規アントラサイクリン抗生物質
US06/849,229 US4734493A (en) 1985-04-12 1986-04-07 Novel anthracycline antibiotics
EP86104931A EP0203329B1 (en) 1985-04-12 1986-04-10 Obelmycin a
DE8686104931T DE3665304D1 (de) 1985-04-12 1986-04-10 Obelmycin a

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60076777A JPS61236792A (ja) 1985-04-12 1985-04-12 新規アントラサイクリン抗生物質

Publications (2)

Publication Number Publication Date
JPS61236792A JPS61236792A (ja) 1986-10-22
JPH0516438B2 true JPH0516438B2 (en, 2012) 1993-03-04

Family

ID=13615020

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60076777A Granted JPS61236792A (ja) 1985-04-12 1985-04-12 新規アントラサイクリン抗生物質

Country Status (4)

Country Link
US (1) US4734493A (en, 2012)
EP (1) EP0203329B1 (en, 2012)
JP (1) JPS61236792A (en, 2012)
DE (1) DE3665304D1 (en, 2012)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3425357A1 (de) * 1984-07-10 1986-01-23 Hoechst Ag, 6230 Frankfurt 1-hydroxy-cytorhodine, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
JPS62238298A (ja) * 1986-04-08 1987-10-19 Sanraku Inc 新規アントラサイクリン抗生物質ｄｃｐ−１及び２
DE3709337A1 (de) * 1987-03-21 1988-10-13 Hoechst Ag Neue anthracyclin-glycoside, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika
DE3712350A1 (de) * 1987-04-11 1988-10-20 Behringwerke Ag Semisynthetische rhodomycine, verfahren zu ihrer herstellung und ihre verwendung als zytostatika
DE3722698A1 (de) * 1987-07-09 1989-01-19 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
FR2630915A1 (fr) * 1988-05-04 1989-11-10 Hoechst Lab Nouveaux glycals, anthracyclines obtenues a l'aide de ces glycals et utilisation desdites anthracyclines en tant que medicaments
FR2630914A1 (fr) * 1988-05-04 1989-11-10 Hoechst Sa Laboratoires Nouveaux analogues du l-fucose, leur procede de preparation, application de ces analogues a la preparation de nouveaux glycals, anthracyclines obtenues a l'aide de ces glycals et utilisation desdites anthracyclines en tant que medicaments
DE3819092A1 (de) * 1988-06-04 1989-12-14 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
US4992376A (en) * 1988-09-19 1991-02-12 Bristol-Myers Company Biological pure culture of Streptomyces violaceus ATCC 53807
WO2016145242A1 (en) * 2015-03-11 2016-09-15 Agenus Inc. Methods and compositions for high throughput screening of biomolecules using gel microdrops

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH637160A5 (fr) * 1976-10-05 1983-07-15 Microbial Chem Res Found Procede de fabrication de glucosides anthracyclines.
JPS6023679B2 (ja) * 1979-07-13 1985-06-08 メルシャン株式会社 ロドマイシン群抗生物質とその製造法
JPS5874694A (ja) * 1981-10-29 1983-05-06 Sanraku Inc アントラサイクリン誘導体
DE3425357A1 (de) * 1984-07-10 1986-01-23 Hoechst Ag, 6230 Frankfurt 1-hydroxy-cytorhodine, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika

Also Published As

Publication number Publication date
EP0203329B1 (en) 1989-08-30
JPS61236792A (ja) 1986-10-22
DE3665304D1 (de) 1989-10-05
EP0203329A1 (en) 1986-12-03
US4734493A (en) 1988-03-29

Similar Documents

Publication Publication Date Title
JPH0516438B2 (en, 2012)
US4612371A (en) Anthracycline antibiotics
JPH0576958B2 (en, 2012)
JPH0479354B2 (en, 2012)
US4918172A (en) Anthracycline antibiotics
JP3069081B2 (ja) 新規制がん性抗生物質
JP4443740B2 (ja) アントラサイクリン抗生物質
JPH051276B2 (en, 2012)
EP0205981B1 (en) A novel anti-tumor and antimicrobial compound, its microbiological preparation and its use as medicament
JPH0625095B2 (ja) 抗生物質ｓｆ−２４１５物質およびその製造法
JP3026862B2 (ja) 新規アントラサイクリン化合物
JPH051277B2 (en, 2012)
JP2701069B2 (ja) 抗腫瘍性アントラサイクリン系化合物
KR960016591B1 (ko) 4'-데옥시-4'-요오도독소루비신을 미생물에 의해 입체 선택적으로 환원시켜 수득한 항종양제
JPS63301893A (ja) アントラサイクリン抗生物質
JP2708800B2 (ja) 新規アントラサイクリン抗生物質
JPS6322800B2 (en, 2012)
DK160879B (da) Anthracyclinantibiotika
JPH08259588A (ja) 新規アントラサイクリン抗生物質
JPS608300A (ja) 新規アントラサイクリン抗生物質
JPS6366194A (ja) 新規なアントラサイクリン抗生物質
JPH09132588A (ja) 新規アントラサイクリン抗生物質
JPH064668B2 (ja) 新規アントラサイクリン抗生物質
JPH0733736A (ja) 新規抗生物質アジセマイシンｂおよびその製造方法
JPH05192176A (ja) β−ロドマイシノンの製造法