JPH05130881A - カルボン酸誘導体の酵素加水分解方法 - Google Patents

カルボン酸誘導体の酵素加水分解方法

Info

Publication number
JPH05130881A
JPH05130881A JP4110468A JP11046892A JPH05130881A JP H05130881 A JPH05130881 A JP H05130881A JP 4110468 A JP4110468 A JP 4110468A JP 11046892 A JP11046892 A JP 11046892A JP H05130881 A JPH05130881 A JP H05130881A
Authority
JP
Japan
Prior art keywords
water
carboxylic acid
organic
solution
hydrolase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP4110468A
Other languages
English (en)
Japanese (ja)
Inventor
Maria Buchner
マリア・ブツヒネル
Robert Estermann
ローベルト・エステルマン
Herbert Mayrhofer
ヘルベルト・マイルホーフエル
Gerald Banko
ゲラルト・バンコ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patheon Austria GmbH and Co KG
Chemie Linz GmbH
Original Assignee
Chemie Linz AG
Chemie Linz GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemie Linz AG, Chemie Linz GmbH filed Critical Chemie Linz AG
Publication of JPH05130881A publication Critical patent/JPH05130881A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP4110468A 1991-04-29 1992-04-28 カルボン酸誘導体の酵素加水分解方法 Withdrawn JPH05130881A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT886/91 1991-04-29
AT0088691A AT398081B (de) 1991-04-29 1991-04-29 Verfahren zur enzymatischen hydrolyse eines carbonsäurederivates

Publications (1)

Publication Number Publication Date
JPH05130881A true JPH05130881A (ja) 1993-05-28

Family

ID=3502090

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4110468A Withdrawn JPH05130881A (ja) 1991-04-29 1992-04-28 カルボン酸誘導体の酵素加水分解方法

Country Status (12)

Country Link
US (1) US5278054A (US20030204162A1-20031030-M00001.png)
EP (1) EP0511526A1 (US20030204162A1-20031030-M00001.png)
JP (1) JPH05130881A (US20030204162A1-20031030-M00001.png)
AT (1) AT398081B (US20030204162A1-20031030-M00001.png)
AU (1) AU662134B2 (US20030204162A1-20031030-M00001.png)
CA (1) CA2065550A1 (US20030204162A1-20031030-M00001.png)
CZ (1) CZ130992A3 (US20030204162A1-20031030-M00001.png)
DK (1) DK0511526T3 (US20030204162A1-20031030-M00001.png)
HU (1) HUT62940A (US20030204162A1-20031030-M00001.png)
NZ (1) NZ242279A (US20030204162A1-20031030-M00001.png)
SK (1) SK130992A3 (US20030204162A1-20031030-M00001.png)
ZA (1) ZA923072B (US20030204162A1-20031030-M00001.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009278930A (ja) * 2008-05-23 2009-12-03 Mitsubishi Gas Chem Co Inc 有機カルボン酸エステルからの光学活性有機カルボン酸の製造方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686275A (en) * 1991-12-23 1997-11-11 Genzyme Ltd. Synthesis of homochiral 2-hydroxy acids
DE4328231C1 (de) * 1993-08-23 1994-07-28 Basf Ag Verfahren zur Herstellung von (L)-2-Chlorpropionsäure und deren Salzen
DE19501452A1 (de) * 1995-01-19 1996-07-25 Basf Ag Verfahren zur Herstellung von optisch aktiven 2-Halogenpropionsäuren
US6022977A (en) * 1997-03-26 2000-02-08 Dupont Pharmaceuticals Company Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids
KR100378741B1 (ko) * 2000-06-01 2003-04-07 에스케이 주식회사 효소를 이용하여 R-폼 또는 S-폼의 α-치환 헤테로싸이클릭 카르복실산 및 이와 상반되는 광학특성을 갖는 α-치환 헤테로싸이클릭 카르복실산 에스테르를 제조하는 방법
JP4843812B2 (ja) * 2000-06-01 2011-12-21 エスケー バイオファーマスティカルズ カンパニー リミテッド 酵素を使用するラセミα−置換ヘテロ環式カルボン酸の光学分割方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4601987A (en) * 1985-02-27 1986-07-22 Massachusetts Institute Of Technology Enzymatic production of optical isomers of 2-halopropionic acids
US4668628A (en) * 1985-04-01 1987-05-26 Stauffer Chemical Company Resolution of racemic mixtures of aliphatic acid esters
JPS6352896A (ja) * 1986-08-22 1988-03-07 ストウフア−　ケミカル　カンパニ− リパ−ゼ酵素反応の実施方法
US5032523A (en) * 1987-01-14 1991-07-16 Lion Corporation Preparation of optically active esters
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
US5057427A (en) * 1988-04-07 1991-10-15 Sepracor, Inc. Method for resolution of stereoisomers
US5108916A (en) * 1989-06-05 1992-04-28 Rhone-Poulenc Rorer, S.A. Process for stereoselectively hydrolyzing, transesterifying or esterifying with immobilized isozyme of lipase from candida rugosa

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009278930A (ja) * 2008-05-23 2009-12-03 Mitsubishi Gas Chem Co Inc 有機カルボン酸エステルからの光学活性有機カルボン酸の製造方法

Also Published As

Publication number Publication date
CZ130992A3 (en) 1994-01-19
ZA923072B (en) 1992-12-30
HUT62940A (en) 1993-06-28
US5278054A (en) 1994-01-11
DK0511526T3 (US20030204162A1-20031030-M00001.png) 1992-11-04
ATA88691A (de) 1994-01-15
HU9201412D0 (en) 1992-07-28
AT398081B (de) 1994-09-26
EP0511526A1 (de) 1992-11-04
NZ242279A (en) 1993-02-25
AU1502492A (en) 1992-11-05
SK130992A3 (en) 1995-08-09
AU662134B2 (en) 1995-08-24
CA2065550A1 (en) 1992-10-30

Similar Documents

Publication Publication Date Title
JPS63273499A (ja) 光学活性化合物の製造法
US5278054A (en) Process for the enzymatic hydrolysis of a carboxylic acid derivative
Wallace et al. Resolution of a chiral ester by lipase-catalyzed transesterification with polyethylene glycol in organic media
RU2144959C1 (ru) Ферментативный гидролиз 4-метилтиобутиронитрилов
US4670395A (en) Enantioselective hydrolysis of N-acylamino acid esters using a combined enzyme system
US5229280A (en) Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid
JPH0656830A (ja) （ｒ，ｓ）−３−キヌクリジノールのエナンチオメリックな濃縮法
US5492830A (en) Enzymatic resolution of α-tertiary carboxylic acid esters
JP3704719B2 (ja) 光学活性３−アミノブタン酸の製造法及びそのエステル中間体
JP2000023693A (ja) 光学活性な２−アセチルチオ−３−フェニルプロピオン酸の製造方法
JPS6012992A (ja) 光学活性カルボン酸の製造法
JPH0191789A (ja) 光学活性β−置換グルタル酸モノエステルの製造法
JP3545442B2 (ja) 光学活性４−（２−ハロ−１−ヒドロキシエチル）−２−トリフルオロメチルチアゾールの製造方法
JPH02273196A (ja) ラセミ化合物の生体触媒分割のエナンチオ選択性の改良法
JPH0587240B2 (US20030204162A1-20031030-M00001.png)
JPH06500458A (ja) ４―ヒドロキシ―２―シクロペンテン―１―オン及び２′，２′―ジメチルプロパン―１′，３′―ジオールとのケタールのｓ（−）―及びｒ（＋）―エステルの酵素によるエナンチオ選択的合成
DE4117255A1 (de) Verfahren zur enzymatischen hydrolyse eines carbonsaeurederivates
JP3192835B2 (ja) （ｓ）−１，３−ブタンジオールの製法
JPH0892269A (ja) 光学活性［３］（１，１’）フェロセノファン類の製造方法
JPH05501049A (ja) Ｒ―（＋）―３―オキソシクロアルカンカルボキシル酸の低級アルキルエステルの製造法
JPH01247100A (ja) 光学活性カルボン酸誘導体の製造方法
JPS6222599A (ja) 光学活性カルボン酸の製造法
JPH03247299A (ja) 生化学的手法による光学活性第２級アルキンアルコールの製造法
JPH0614797A (ja) 光学活性２−アリールプロピオン酸及びそのエステルの製造方法
JPH07327692A (ja) 光学活性β−ヒドロキシカルボン酸及びその対掌体エステルの製造方法

Legal Events

Date Code Title Description
A300 Application deemed to be withdrawn because no request for examination was validly filed

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 19990706