JPH048422B2 - - Google Patents
Info
- Publication number
- JPH048422B2 JPH048422B2 JP54101153A JP10115379A JPH048422B2 JP H048422 B2 JPH048422 B2 JP H048422B2 JP 54101153 A JP54101153 A JP 54101153A JP 10115379 A JP10115379 A JP 10115379A JP H048422 B2 JPH048422 B2 JP H048422B2
- Authority
- JP
- Japan
- Prior art keywords
- water
- toluene
- solvent
- imidate
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 154
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 claims description 62
- 239000000243 solution Substances 0.000 claims description 50
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 44
- CEIPQQODRKXDSB-UHFFFAOYSA-N ethyl 3-(6-hydroxynaphthalen-2-yl)-1H-indazole-5-carboximidate dihydrochloride Chemical compound Cl.Cl.C1=C(O)C=CC2=CC(C3=NNC4=CC=C(C=C43)C(=N)OCC)=CC=C21 CEIPQQODRKXDSB-UHFFFAOYSA-N 0.000 claims description 36
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 34
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 33
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 33
- FBXGQDUVJBKEAJ-UHFFFAOYSA-N 4h-oxazin-3-one Chemical compound O=C1CC=CON1 FBXGQDUVJBKEAJ-UHFFFAOYSA-N 0.000 claims description 31
- WASQWSOJHCZDFK-UHFFFAOYSA-N diketene Chemical compound C=C1CC(=O)O1 WASQWSOJHCZDFK-UHFFFAOYSA-N 0.000 claims description 30
- 239000000203 mixture Substances 0.000 claims description 28
- 239000002904 solvent Substances 0.000 claims description 24
- 239000012071 phase Substances 0.000 claims description 21
- AJPIUNPJBFBUKK-UHFFFAOYSA-N 2-isopropyl-6-methylpyrimidin-4-ol Chemical compound CC(C)C1=NC(C)=CC(O)=N1 AJPIUNPJBFBUKK-UHFFFAOYSA-N 0.000 claims description 19
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 claims description 15
- 238000010533 azeotropic distillation Methods 0.000 claims description 15
- 239000008346 aqueous phase Substances 0.000 claims description 13
- VTGOHKSTWXHQJK-UHFFFAOYSA-N pyrimidin-2-ol Chemical compound OC1=NC=CC=N1 VTGOHKSTWXHQJK-UHFFFAOYSA-N 0.000 claims description 13
- 239000003054 catalyst Substances 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 11
- 229910021529 ammonia Inorganic materials 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 10
- 125000000217 alkyl group Chemical group 0.000 claims description 9
- 239000002585 base Substances 0.000 claims description 9
- 238000006386 neutralization reaction Methods 0.000 claims description 9
- 239000007787 solid Substances 0.000 claims description 9
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 8
- CYTYCFOTNPOANT-UHFFFAOYSA-N Perchloroethylene Chemical group ClC(Cl)=C(Cl)Cl CYTYCFOTNPOANT-UHFFFAOYSA-N 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 7
- 229950011008 tetrachloroethylene Drugs 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 6
- UBOXGVDOUJQMTN-UHFFFAOYSA-N 1,1,2-trichloroethane Chemical compound ClCC(Cl)Cl UBOXGVDOUJQMTN-UHFFFAOYSA-N 0.000 claims description 5
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical group ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 claims description 5
- 239000007864 aqueous solution Substances 0.000 claims description 5
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 5
- 239000003960 organic solvent Substances 0.000 claims description 5
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 claims description 4
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 150000007530 organic bases Chemical class 0.000 claims description 4
- 239000002274 desiccant Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000002808 molecular sieve Substances 0.000 claims description 3
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 claims description 3
- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 claims description 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 claims description 2
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 claims description 2
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims description 2
- 150000004945 aromatic hydrocarbons Chemical class 0.000 claims description 2
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 150000007529 inorganic bases Chemical class 0.000 claims description 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 2
- 125000005270 trialkylamine group Chemical group 0.000 claims description 2
- 239000008096 xylene Substances 0.000 claims description 2
- 125000003944 tolyl group Chemical group 0.000 claims 2
- 229910000288 alkali metal carbonate Inorganic materials 0.000 claims 1
- 150000008041 alkali metal carbonates Chemical class 0.000 claims 1
- 239000011260 aqueous acid Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 description 29
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 17
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 17
- 239000011541 reaction mixture Substances 0.000 description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 11
- 239000000047 product Substances 0.000 description 10
- 238000001816 cooling Methods 0.000 description 9
- 239000012074 organic phase Substances 0.000 description 9
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
- 238000004821 distillation Methods 0.000 description 6
- 239000007789 gas Substances 0.000 description 5
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 description 4
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 4
- 235000019441 ethanol Nutrition 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- 238000010907 mechanical stirring Methods 0.000 description 4
- -1 organic acid ester Chemical class 0.000 description 4
- 238000010992 reflux Methods 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- UAUSQEVPWPGBHG-IHWYPQMZSA-N (z)-3-aminobut-2-enamide Chemical compound C\C(N)=C\C(N)=O UAUSQEVPWPGBHG-IHWYPQMZSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 239000007795 chemical reaction product Substances 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000007858 starting material Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 229960000583 acetic acid Drugs 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 229910052783 alkali metal Inorganic materials 0.000 description 2
- RBHJBMIOOPYDBQ-UHFFFAOYSA-N carbon dioxide;propan-2-one Chemical compound O=C=O.CC(C)=O RBHJBMIOOPYDBQ-UHFFFAOYSA-N 0.000 description 2
- FHIVAFMUCKRCQO-UHFFFAOYSA-N diazinon Chemical compound CCOP(=S)(OCC)OC1=CC(C)=NC(C(C)C)=N1 FHIVAFMUCKRCQO-UHFFFAOYSA-N 0.000 description 2
- VILAVOFMIJHSJA-UHFFFAOYSA-N dicarbon monoxide Chemical group [C]=C=O VILAVOFMIJHSJA-UHFFFAOYSA-N 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000005755 formation reaction Methods 0.000 description 2
- 150000002463 imidates Chemical class 0.000 description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000000269 nucleophilic effect Effects 0.000 description 2
- 125000004430 oxygen atom Chemical group O* 0.000 description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
- 239000000376 reactant Substances 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 description 2
- 235000011152 sodium sulphate Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- LHRIUKSRPHFASO-UHFFFAOYSA-N 6-methyl-1h-pyrimidin-4-one Chemical compound CC1=CC(=O)N=CN1 LHRIUKSRPHFASO-UHFFFAOYSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 230000000895 acaricidal effect Effects 0.000 description 1
- 239000000642 acaricide Substances 0.000 description 1
- 150000008065 acid anhydrides Chemical class 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- YOWJPLAOQQQSIQ-UHFFFAOYSA-N dihydroxy-(6-methyl-2-propan-2-ylpyrimidin-4-yl)oxy-sulfanylidene-$l^{5}-phosphane Chemical compound CC(C)C1=NC(C)=CC(OP(O)(O)=S)=N1 YOWJPLAOQQQSIQ-UHFFFAOYSA-N 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- ZXZQXWVPGASIQP-UHFFFAOYSA-N ethyl 2-methylpropanimidate Chemical compound CCOC(=N)C(C)C ZXZQXWVPGASIQP-UHFFFAOYSA-N 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- BPMGFNCDRVFXEG-UHFFFAOYSA-N methyl 2-methylpropanimidate Chemical compound COC(=N)C(C)C BPMGFNCDRVFXEG-UHFFFAOYSA-N 0.000 description 1
- RMXGPHAHPIIESQ-UHFFFAOYSA-N methyl 2-methylpropanimidate;hydrochloride Chemical compound Cl.COC(=N)C(C)C RMXGPHAHPIIESQ-UHFFFAOYSA-N 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 238000006798 ring closing metathesis reaction Methods 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- CMQCNTNASCDNGR-UHFFFAOYSA-N toluene;hydrate Chemical compound O.CC1=CC=CC=C1 CMQCNTNASCDNGR-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Description
ãç£æ¥äžã®å©çšåéã
æ¬çºæã¯æ¬¡åŒïŒ
ïŒåŒäžãã¯ã¢ã«ãã«åºãè¡šãããïŒ
ã§è¡šããããïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâã
ãããã·ããªããžã³ã®æ°èŠã§åªãã補é æ¹æ³ã«é¢
ãããã®ã§ããã ã¢ã«ãã«åºãšããŠã®ïŒ²ã¯ãççŽ ååæ°ïŒãªãã
ïŒã®çŽéãŸãã¯æåãéã®äœçŽã¢ã«ãã«åºãäŸã
ã°ã¡ãã«åºããšãã«åºãïœâãããã«åºãã€ãœã
ããã«åºãïœâããã«åºã第äºããã«åºãã€ãœã
ãã«åºãŸãã¯ç¬¬äžããã«åºã§ããã ãåŸæ¥ã®æè¡ã åŒã§è¡šããããååç©ã¯ãäŸãã°ç±³åœç¹èš±ç¬¬
2754243å·ã«é瀺ããã³ç¹èš±è«æ±ãããŠãã眮æ
ããããã·ããªããžã³ã®ãªã³é žãšã¹ãã«ããã³ç¹
ã«åžå ŽäŸ¡å€ã®éåžžã«é«ãïŒïŒïŒâãžãšãã«âïŒâ
ïŒïŒâã€ãœãããã«âïŒâã¡ãã«âïŒâããªããž
ã«ïŒâããªãã¹ããšãŒãããã€ã¢ãžãã³
ïŒDIAZINONïŒãã®è£œé ã®ããã®éèŠãªäžéäœã§
ããããã€ã¢ãžãã³ã¯å®è©ã®ãã殺è«æ®ºããå€ã§
ããã害è«ã®é²é€ã«æçšã§ããã ãã®çœ®æããããã·ããªããžã³ã¯ãåŸæ¥ä»¥äžã«
瀺ãç ©éãªå€æ°å·¥çšæ³ã§è£œé ãããŠããïŒ è¿å¹ŽãäžèšåŸæ¥ã®è£œé æ³ã¯æ¹è¯ããã1977幎ïŒ
æ29æ¥ã«çºè¡ãããç±³åœç¹èš±ç¬¬4014879å·ã§ç¹èš±
è«æ±ãããŠããé£ç¶éç°ïŒäžåæ¹æ³ã«è³ã€ãŠå®æ
ãããã äžèšã®æ¹æ³ã«ä»£ããã®ããããã·ããªããžã³ã®
補é æ¹æ³ã¯ãæ¥æ¬ç¹èš±æç®ã«å ±åãããŠãããæ¥
æ¬ç¹èš±ç¬¬557103å·ã«ã¯ãã®ããããã·ããªããžã³
ããβâã¢ããã¯ããã³ã¢ããïŒãžã±ãã³ããã³
ã¢ã³ã¢ãã¢ããèªå°ããããã®ïŒããã³é žãã©ã€
ããŸãã¯é žç¡æ°Žç©ãã補é ãããβâã¢ã·ã«ã¢ã
ãã¯ããã³ã¢ããããçš®ã ã®ç±åŠçã«ãã€ãŠè£œé
ãããããšãé瀺ãããŠãããç¹å ¬æ48â39942
å·ã«ã¯ãã®ããããã·ããªããžã³ãβâã¢ããã¯
ããã³ã¢ããããã³ææ©é žãšã¹ãã«ãããçš®ã®ã¢
ã«ã«ãªåå¿äœãäŸãã°ã¢ã«ã«ãªéå±ãŸãã¯ãã®ã¢
ã«ã³ã¬ãŒãã®ååšäžã§åå¿ãããŠè£œé åºæ¥ãããš
ãé瀺ãããŠããã è¿å¹ŽãåŒã§è¡šããããååç©ã補é ããå¥ã®
æ¹æ³ãã1977幎ïŒæ19æ¥ã«çºè¡ãããç±³åœç¹èš±ç¬¬
4018771å·ããã³1977幎10æïŒæ¥ã«çºè¡ãããç±³
åœç¹èš±ç¬¬4052396å·ããã³ç±³åœç¹èš±ç¬¬4052397å·ã
å«ããŠããã€ãç¹èš±ãããã ç±³åœç¹èš±ç¬¬4018771å·ã«ã¯ããžã±ãã³ãäœçŽã¢
ã«ã«ããŒã«é žã¢ãããšè§Šåªååšäžã§åå¿ãããåŸ
ãããâã¢ã»ãã¢ã»ãã«ã¢ã«ã«ããŒã«é žã¢ãã
ãé žæ§è§Šåªã®ååšäžã§ã¢ã³ã¢ãã¢ã§åŠçããããš
ã«ãããããã®ååç©ã®åææ³ãé瀺ãããŠã
ãã ç±³åœç¹èš±ç¬¬4052396å·ã«ã¯ããžã±ãã³ãã¢ã«ã«
ããŒã«é žãããªã«ãšé žæ§è§Šåªã®ååšäžã§åå¿ã
ããç¶ããŠåå¿çæç©ãã¢ã³ã¢ãã¢ã§åŠçããæ¹
æ³ãé瀺ãããŠããã ç±³åœç¹èš±ç¬¬4052397å·ã«ã¯ãææ©æº¶åªäžã§ããž
ã±ãã³ãã¢ã³ã¢ãã¢ã§åŠçããã²ãç¶ããŠé£ç¶ç
ã«ãåŸãããβâã¢ããã¯ããã³ã¢ãããæ°Žåã
é€å»ããåŸã«ã¢ã«ã«ããŒã«é žãšã¹ãã«ããã³ã¢ã«
ã«ãªéå±ã¢ã«ã³ãã·ãã§åŠçããããšã«ããåŒ
ã§è¡šããããããããã·ããªããžã³ã®è£œé ãèšèŒ
ãããŠããã ãçºæã解決ããããšãã課é¡ã ããããªããããããã®å šãŠã®å è¡æè¡ã®æ¹æ³
ã¯ãå¹ççããã³çµæžçãªåæ¥ç倧éçç£ã®èŠ³ç¹
ããã¯å åãªãã®ã§ã¯ãªãããããã€ãŠæ¬çºæã®
ç®çã¯ãã®ç©è³ªã®è¯å¥œãªåææ³ãæäŸããããšã§
ããã ã課é¡ã解決ããããã®æ段ã æ¬çºæã¯ãäºæããã¬ããšãªãããåæã«ãŒã
ã®æåã®å®¹æã«è£œé ãããã€ãããŒãïŒã€ããž
ã³ïŒå¡©é žå¡©äžéäœãåºçºç©ãšãããã®äžéäœãã
ã®çæç©ãç°¡åãªå·¥çšã§ãããæäœãŸãã¯é£ç¶æ
äœã«ãã補é ããç®ççæç©ã奜åçããã³é«çŽ
床ã§åŸãããã®åªããäœã³ã¹ãã®æè¡ãæäŸãã
ãã®ã§ãããæž©åãªæ¡ä»¶ã§å®¹æã«é²è¡ãããã®æ¹
æ³ã¯ã次åŒïŒ ïŒåŒäžã ã¯ççŽ ååæ°ïŒãªããïŒã®ã¢ã«ãã«åºãè¡šã
ãã Râ²ã¯ççŽ ååæ°ïŒãªããïŒã®ã¢ã«ãã«åºãè¡š
ãããïŒã§è¡šããããã€ãããŒãå¡©é žå¡©ãšéå°ã®
å¡©åæ°ŽçŽ ãšã®æ··åç©ãæ°Žäžæ··åæ§æº¶åªã®ååšäžã§
æ°Žæ§æº¶æ¶²äžã®é žå容æ§åŒ·å¡©åºã«ããäžåããŠéé¢
ã€ãããŒããåŸãããšãæåã®å·¥çšãšããŠå«ãã§
ããã å³ã¡ããã®éé¢ã€ãããŒãã¯ã€ãããŒãïŒã¢ã«
åœããå¡©åæ°ŽçŽ ãïŒãªããïŒã¢ã«å«æããæ··åç©
ãäžåããããšã«ããããã®å·¥çšã«ãããŠåŸãã
ãã éé¢ã€ãããŒããå«æããææ©çžãæ°Žçžããå
é¢ãã也ç¥ããŠã€ãããŒããææ©æº¶æ¶²äžã§è§Šåªã®
ååšäžããžã±ãã³ãšåå¿ãããŠæ¬¡åŒïŒ ïŒåŒäžãããã³Râ²ã¯åèšã®æå³ãè¡šãããïŒ ã§è¡šãããããªããµãžãã³ãåŸãã ãžã±ãã³ã®æ·»å å®äºåŸãåŸãããææ©æº¶æ¶²äžã®
åèšãªããµãžãã³ãã¢ã³ã¢ãã¢ã¬ã¹ãšåå¿ãã
ããçããæ°Žã¯å šãŠé€å»ããææ©æº¶åªãé€å»ã
ãŠãïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâããããã·
ããªããžã³ãå®è³ªçã«çŽç²ç©è³ªãšããŠè¯å¥œãªåç
ã§åŸãã æ¬çºæã®æ¹æ³ã®åºæ¬çåå¿æ§åŒã¯æ¬¡ã®ããã§ã
ãïŒ åºçºã€ãããŒãå¡©é žå¡©ã¯ãç±³åœç¹èš±ç¬¬2754243
å·ããã³ç±³åœç¹èš±ç¬¬4014879å·ã«èšèŒã®æ¹æ³ã§åŸ
ããããããã®æ¹æ³ã«ãã€ãŠæ¬çºæã®çš®ã ã®ïŒâ
ã¢ã«ãã«âïŒâã¡ãã«âïŒâããããã·ããªããž
ã³ã®åºçºç©è³ªãåŸãããšãã§ããã ãã®ãããªåŒã§è¡šããããåºçºç©è³ªã®ãã¡ã
åŒäžã®Râ²ãã¡ãã«åºããšãã«åºããããã«åºãŸ
ãã¯ããã«åºãè¡šããçš®ã ã®ã€ãããŒããšã¹ãã«
ã䜿çšå¯èœã§ããããRâ²ããšãã«åºã§ãããã®
ã奜ãŸããã ã€ãããŒããšã¹ãã«å¡©ã®äžååå¿ã¯ãé žå容æ§
匷塩åºãšã®åå¿ã«ãã€ãŠè¡ãªãããã該塩åºã¯ç¡
æ©å¡©åºãäŸãã°ã¢ã«ã«ãªéå±æ°Žé žåç©ããã³ã¢ã«
ã«ãªéå±çé žå¡©ãŸãã¯ææ©ã®é žå容æ§å¡©åºã§ãã€
ãŠããããã®é žå容æ§ææ©å¡©åºã®ãã¡ã§ã¯ãã¢ã«
ãã«éšåã®ççŽ ååæ°ãïŒãªããïŒã®ããªã¢ã«ã
ã«ã¢ãã³ãäŸãã°ããªã¡ãã«ã¢ãã³ãŸãã¯ããªãš
ãã«ã¢ãã³ãéåžžã«é©ããããããªã¡ãã«ã¢ãã³
ã奜ãŸãããããªãžã³ããŸãåªããé žå容æ§å¡©åº
ã§ããã äžåããéé¢ã€ãããŒãã溶解ããã®ã«äœ¿çšã
ãæ°Žäžæ··åæ§æº¶åªãšããŠã¯ããã³ãŒã³ããã«ãš
ã³ããã·ã¬ã³ããããµã³ãããã¿ã³ãïŒïŒïŒïŒïŒ
âããªã¯ãããšã¿ã³ãïŒïŒïŒïŒïŒâããªã¯ãããš
ã¿ã³ãããã©ã¯ãããšãã¬ã³ããžã¯ããã¡ã¿ã³ã
ãšãã¬ã³ãžã¯ãã©ã€ããå«ãã液ç¶ã®è³éŠæãã
ã³èèªæçåæ°ŽçŽ ããã³æ¶²ç¶ã®å¡©çŽ åçåæ°ŽçŽ ã
ããããããããã«ãšã³ã䜿çšãããšæ¬¡ã«æ°Žãé€
å»ããã®ãéåžžã«å®¹æã«ãªãã®ã§å¥œãŸããã ãã®åå¿å·¥çšã®æž©åºŠç¯å²ã¯ãâ30ãªãã50âã§
ãããã奜ãŸããç¯å²ã¯â10ãªãã25âã§ããã
æã奜ãŸããç¯å²ã¯ïŒãªãã10âã§ãããããã
ãªããããã®åå¿å·¥çšãé£ç¶çã«è¡ãªãå Žåã«
ã¯ã枩床ã¯å¥œãŸããã¯10ãªãã20âã®ç¯å²ã«ããª
ããã°ãªããªãã ãã®å·¥çšã®åå¿æéã¯ïŒãªãã120åã§ããã
ããã奜ãŸããã¯10ãªãã60åã®éã§ããã æ°Žãé€å»ããããšã¯ãããçŽç²ãªçæç©ããã
奜åçã§åŸãããšã«ã€ãªããã®ã§ãåæ¥ççç£ã«
ãšã€ãŠéèŠã§ãããæ°Žã¯åããéé¢ã€ãããŒãã
溶解ããŠããæ°Žäžæ··åæ§ææ©æº¶åªçžãåé¢ããã
ãšã«ãã€ãŠé€ãããã 溶åªäžã«æ®ã€ãŠããæ°Žã¯å šãŠãå ±æ²žèžçã«ã
ãããŸãã¯ã¢ã¬ããŠã©ãŒã·ãŒããŸãã¯ç¡æ°Žç¡«é žã
ããªãŠã ã®ãããªä¹Ÿç¥çšç¡æ°Žå¡©ã®ãããªä¹Ÿç¥å€ãš
æ¥è§Šãããããšã«ããé€ãããããããã®ä¹Ÿç¥å·¥
çšã®ãã¡ãå®éšå®€ã§ã®è£œé ã«ã¯æ¥è§Šä¹Ÿç¥å€ã奜ãŸ
ããããå·¥æ¥èŠæš¡ã®è£œé ã«ã¯å ±æ²žèžçã奜ãŸã
ãã 也ç¥ã€ãããŒãå¡©åºã次ã«ãžã±ãã³ãšåå¿ãã
ãŠåèšãªããµãžãã³ã圢æããããã€ãããŒãã
ãã³ãžã±ãã³ã¯å¥œãŸããã¯æº¶åªäžã«æº¶è§£ãããªã
ãã°ãªããªãã å ±æ²žèžçãäŸãã°ãã«ãšã³ãããã©ã¯ãããšã
ã¬ã³ãŸãã¯ããªã¯ãããšãã¬ã³ã䜿çšããããšã
奜ãŸãããããããäºãã«æ··åæ§ã®æº¶åªã§ããã°
åæåã«å¯Ÿããåã ã®æº¶åªã䜿çšããããšãå¯èœ
ã§ããããã«ãšã³ã奜ãŸããã éé¢ã€ãããŒããšãžã±ãã³ãšã®åå¿ã¯ãããªã¡
ãã«ã¢ãã³ãããã¯ããªãšãã«ã¢ãã³ãŸãã¯é ¢é ž
ã®ååšäžã§è¡ãªããããäžè¬çã«è§Šåªã¯åå¿äœã«
察ããŠ0.1ãªãã2.5ã¢ã«ïŒ ã®éã§äœ¿çšããããšã
ã§ãã奜ãŸããã¯ïŒãªãã10ã¢ã«ïŒ ãæã奜ãŸã
ãã¯2.5ãªããïŒã¢ã«ïŒ ã®éã§äœ¿çšãããã 䜿çšãããžã±ãã³ã®éã¯ãåèšéé¢ã€ãããŒã
ïŒã¢ã«åœããïŒãªãã1.05ã¢ã«ã§ããã倧éå°ã«
ããŠãå©ç¹ã¯åŸãããªãã åèšãªããµãžãã³åœ¢æã®åå¿ã¯çºç±åå¿ã§ã
ãããããåèšãªããµãžãã³ã¯çŽ40âã§å解ãå§
ããããšãç¥ãããŠããã®ã§ãåå¿å®¹åšã¯å·åŽã
ãå¿ èŠãããã容åšã35â以äžã«å·åŽããããšã«
ãããç¹ã«çµæžçã«æã䟡å€ã®é«ãïŒâã€ãœãã
ãã«âïŒâã¡ãã«âïŒâããããã·ããªããžã³ã®
å Žåã«ãé«çŽåºŠã®çæç©ãé«åçã§åŸããããã
ããã€ãŠããã®åå¿ã®æž©åºŠã¯ïŒãªãã60âã奜ãŸ
ããã¯15ãªãã35âã®éã§ãããåå¿ã¯ïŒæé以
å ã«å®äºããã äžèšå·¥çšïœïŒã«ãããŠã¯ãéé¢ã€ãããŒããšãž
ã±ãã³ãåå¿ããŠãªããµãžãã³ã圢æããããã
ã®ãªããµãžãã³ã®æ§é ãå³ã¡
ãããã·ããªããžã³ã®æ°èŠã§åªãã補é æ¹æ³ã«é¢
ãããã®ã§ããã ã¢ã«ãã«åºãšããŠã®ïŒ²ã¯ãççŽ ååæ°ïŒãªãã
ïŒã®çŽéãŸãã¯æåãéã®äœçŽã¢ã«ãã«åºãäŸã
ã°ã¡ãã«åºããšãã«åºãïœâãããã«åºãã€ãœã
ããã«åºãïœâããã«åºã第äºããã«åºãã€ãœã
ãã«åºãŸãã¯ç¬¬äžããã«åºã§ããã ãåŸæ¥ã®æè¡ã åŒã§è¡šããããååç©ã¯ãäŸãã°ç±³åœç¹èš±ç¬¬
2754243å·ã«é瀺ããã³ç¹èš±è«æ±ãããŠãã眮æ
ããããã·ããªããžã³ã®ãªã³é žãšã¹ãã«ããã³ç¹
ã«åžå ŽäŸ¡å€ã®éåžžã«é«ãïŒïŒïŒâãžãšãã«âïŒâ
ïŒïŒâã€ãœãããã«âïŒâã¡ãã«âïŒâããªããž
ã«ïŒâããªãã¹ããšãŒãããã€ã¢ãžãã³
ïŒDIAZINONïŒãã®è£œé ã®ããã®éèŠãªäžéäœã§
ããããã€ã¢ãžãã³ã¯å®è©ã®ãã殺è«æ®ºããå€ã§
ããã害è«ã®é²é€ã«æçšã§ããã ãã®çœ®æããããã·ããªããžã³ã¯ãåŸæ¥ä»¥äžã«
瀺ãç ©éãªå€æ°å·¥çšæ³ã§è£œé ãããŠããïŒ è¿å¹ŽãäžèšåŸæ¥ã®è£œé æ³ã¯æ¹è¯ããã1977幎ïŒ
æ29æ¥ã«çºè¡ãããç±³åœç¹èš±ç¬¬4014879å·ã§ç¹èš±
è«æ±ãããŠããé£ç¶éç°ïŒäžåæ¹æ³ã«è³ã€ãŠå®æ
ãããã äžèšã®æ¹æ³ã«ä»£ããã®ããããã·ããªããžã³ã®
補é æ¹æ³ã¯ãæ¥æ¬ç¹èš±æç®ã«å ±åãããŠãããæ¥
æ¬ç¹èš±ç¬¬557103å·ã«ã¯ãã®ããããã·ããªããžã³
ããβâã¢ããã¯ããã³ã¢ããïŒãžã±ãã³ããã³
ã¢ã³ã¢ãã¢ããèªå°ããããã®ïŒããã³é žãã©ã€
ããŸãã¯é žç¡æ°Žç©ãã補é ãããβâã¢ã·ã«ã¢ã
ãã¯ããã³ã¢ããããçš®ã ã®ç±åŠçã«ãã€ãŠè£œé
ãããããšãé瀺ãããŠãããç¹å ¬æ48â39942
å·ã«ã¯ãã®ããããã·ããªããžã³ãβâã¢ããã¯
ããã³ã¢ããããã³ææ©é žãšã¹ãã«ãããçš®ã®ã¢
ã«ã«ãªåå¿äœãäŸãã°ã¢ã«ã«ãªéå±ãŸãã¯ãã®ã¢
ã«ã³ã¬ãŒãã®ååšäžã§åå¿ãããŠè£œé åºæ¥ãããš
ãé瀺ãããŠããã è¿å¹ŽãåŒã§è¡šããããååç©ã補é ããå¥ã®
æ¹æ³ãã1977幎ïŒæ19æ¥ã«çºè¡ãããç±³åœç¹èš±ç¬¬
4018771å·ããã³1977幎10æïŒæ¥ã«çºè¡ãããç±³
åœç¹èš±ç¬¬4052396å·ããã³ç±³åœç¹èš±ç¬¬4052397å·ã
å«ããŠããã€ãç¹èš±ãããã ç±³åœç¹èš±ç¬¬4018771å·ã«ã¯ããžã±ãã³ãäœçŽã¢
ã«ã«ããŒã«é žã¢ãããšè§Šåªååšäžã§åå¿ãããåŸ
ãããâã¢ã»ãã¢ã»ãã«ã¢ã«ã«ããŒã«é žã¢ãã
ãé žæ§è§Šåªã®ååšäžã§ã¢ã³ã¢ãã¢ã§åŠçããããš
ã«ãããããã®ååç©ã®åææ³ãé瀺ãããŠã
ãã ç±³åœç¹èš±ç¬¬4052396å·ã«ã¯ããžã±ãã³ãã¢ã«ã«
ããŒã«é žãããªã«ãšé žæ§è§Šåªã®ååšäžã§åå¿ã
ããç¶ããŠåå¿çæç©ãã¢ã³ã¢ãã¢ã§åŠçããæ¹
æ³ãé瀺ãããŠããã ç±³åœç¹èš±ç¬¬4052397å·ã«ã¯ãææ©æº¶åªäžã§ããž
ã±ãã³ãã¢ã³ã¢ãã¢ã§åŠçããã²ãç¶ããŠé£ç¶ç
ã«ãåŸãããβâã¢ããã¯ããã³ã¢ãããæ°Žåã
é€å»ããåŸã«ã¢ã«ã«ããŒã«é žãšã¹ãã«ããã³ã¢ã«
ã«ãªéå±ã¢ã«ã³ãã·ãã§åŠçããããšã«ããåŒ
ã§è¡šããããããããã·ããªããžã³ã®è£œé ãèšèŒ
ãããŠããã ãçºæã解決ããããšãã課é¡ã ããããªããããããã®å šãŠã®å è¡æè¡ã®æ¹æ³
ã¯ãå¹ççããã³çµæžçãªåæ¥ç倧éçç£ã®èŠ³ç¹
ããã¯å åãªãã®ã§ã¯ãªãããããã€ãŠæ¬çºæã®
ç®çã¯ãã®ç©è³ªã®è¯å¥œãªåææ³ãæäŸããããšã§
ããã ã課é¡ã解決ããããã®æ段ã æ¬çºæã¯ãäºæããã¬ããšãªãããåæã«ãŒã
ã®æåã®å®¹æã«è£œé ãããã€ãããŒãïŒã€ããž
ã³ïŒå¡©é žå¡©äžéäœãåºçºç©ãšãããã®äžéäœãã
ã®çæç©ãç°¡åãªå·¥çšã§ãããæäœãŸãã¯é£ç¶æ
äœã«ãã補é ããç®ççæç©ã奜åçããã³é«çŽ
床ã§åŸãããã®åªããäœã³ã¹ãã®æè¡ãæäŸãã
ãã®ã§ãããæž©åãªæ¡ä»¶ã§å®¹æã«é²è¡ãããã®æ¹
æ³ã¯ã次åŒïŒ ïŒåŒäžã ã¯ççŽ ååæ°ïŒãªããïŒã®ã¢ã«ãã«åºãè¡šã
ãã Râ²ã¯ççŽ ååæ°ïŒãªããïŒã®ã¢ã«ãã«åºãè¡š
ãããïŒã§è¡šããããã€ãããŒãå¡©é žå¡©ãšéå°ã®
å¡©åæ°ŽçŽ ãšã®æ··åç©ãæ°Žäžæ··åæ§æº¶åªã®ååšäžã§
æ°Žæ§æº¶æ¶²äžã®é žå容æ§åŒ·å¡©åºã«ããäžåããŠéé¢
ã€ãããŒããåŸãããšãæåã®å·¥çšãšããŠå«ãã§
ããã å³ã¡ããã®éé¢ã€ãããŒãã¯ã€ãããŒãïŒã¢ã«
åœããå¡©åæ°ŽçŽ ãïŒãªããïŒã¢ã«å«æããæ··åç©
ãäžåããããšã«ããããã®å·¥çšã«ãããŠåŸãã
ãã éé¢ã€ãããŒããå«æããææ©çžãæ°Žçžããå
é¢ãã也ç¥ããŠã€ãããŒããææ©æº¶æ¶²äžã§è§Šåªã®
ååšäžããžã±ãã³ãšåå¿ãããŠæ¬¡åŒïŒ ïŒåŒäžãããã³Râ²ã¯åèšã®æå³ãè¡šãããïŒ ã§è¡šãããããªããµãžãã³ãåŸãã ãžã±ãã³ã®æ·»å å®äºåŸãåŸãããææ©æº¶æ¶²äžã®
åèšãªããµãžãã³ãã¢ã³ã¢ãã¢ã¬ã¹ãšåå¿ãã
ããçããæ°Žã¯å šãŠé€å»ããææ©æº¶åªãé€å»ã
ãŠãïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâããããã·
ããªããžã³ãå®è³ªçã«çŽç²ç©è³ªãšããŠè¯å¥œãªåç
ã§åŸãã æ¬çºæã®æ¹æ³ã®åºæ¬çåå¿æ§åŒã¯æ¬¡ã®ããã§ã
ãïŒ åºçºã€ãããŒãå¡©é žå¡©ã¯ãç±³åœç¹èš±ç¬¬2754243
å·ããã³ç±³åœç¹èš±ç¬¬4014879å·ã«èšèŒã®æ¹æ³ã§åŸ
ããããããã®æ¹æ³ã«ãã€ãŠæ¬çºæã®çš®ã ã®ïŒâ
ã¢ã«ãã«âïŒâã¡ãã«âïŒâããããã·ããªããž
ã³ã®åºçºç©è³ªãåŸãããšãã§ããã ãã®ãããªåŒã§è¡šããããåºçºç©è³ªã®ãã¡ã
åŒäžã®Râ²ãã¡ãã«åºããšãã«åºããããã«åºãŸ
ãã¯ããã«åºãè¡šããçš®ã ã®ã€ãããŒããšã¹ãã«
ã䜿çšå¯èœã§ããããRâ²ããšãã«åºã§ãããã®
ã奜ãŸããã ã€ãããŒããšã¹ãã«å¡©ã®äžååå¿ã¯ãé žå容æ§
匷塩åºãšã®åå¿ã«ãã€ãŠè¡ãªãããã該塩åºã¯ç¡
æ©å¡©åºãäŸãã°ã¢ã«ã«ãªéå±æ°Žé žåç©ããã³ã¢ã«
ã«ãªéå±çé žå¡©ãŸãã¯ææ©ã®é žå容æ§å¡©åºã§ãã€
ãŠããããã®é žå容æ§ææ©å¡©åºã®ãã¡ã§ã¯ãã¢ã«
ãã«éšåã®ççŽ ååæ°ãïŒãªããïŒã®ããªã¢ã«ã
ã«ã¢ãã³ãäŸãã°ããªã¡ãã«ã¢ãã³ãŸãã¯ããªãš
ãã«ã¢ãã³ãéåžžã«é©ããããããªã¡ãã«ã¢ãã³
ã奜ãŸãããããªãžã³ããŸãåªããé žå容æ§å¡©åº
ã§ããã äžåããéé¢ã€ãããŒãã溶解ããã®ã«äœ¿çšã
ãæ°Žäžæ··åæ§æº¶åªãšããŠã¯ããã³ãŒã³ããã«ãš
ã³ããã·ã¬ã³ããããµã³ãããã¿ã³ãïŒïŒïŒïŒïŒ
âããªã¯ãããšã¿ã³ãïŒïŒïŒïŒïŒâããªã¯ãããš
ã¿ã³ãããã©ã¯ãããšãã¬ã³ããžã¯ããã¡ã¿ã³ã
ãšãã¬ã³ãžã¯ãã©ã€ããå«ãã液ç¶ã®è³éŠæãã
ã³èèªæçåæ°ŽçŽ ããã³æ¶²ç¶ã®å¡©çŽ åçåæ°ŽçŽ ã
ããããããããã«ãšã³ã䜿çšãããšæ¬¡ã«æ°Žãé€
å»ããã®ãéåžžã«å®¹æã«ãªãã®ã§å¥œãŸããã ãã®åå¿å·¥çšã®æž©åºŠç¯å²ã¯ãâ30ãªãã50âã§
ãããã奜ãŸããç¯å²ã¯â10ãªãã25âã§ããã
æã奜ãŸããç¯å²ã¯ïŒãªãã10âã§ãããããã
ãªããããã®åå¿å·¥çšãé£ç¶çã«è¡ãªãå Žåã«
ã¯ã枩床ã¯å¥œãŸããã¯10ãªãã20âã®ç¯å²ã«ããª
ããã°ãªããªãã ãã®å·¥çšã®åå¿æéã¯ïŒãªãã120åã§ããã
ããã奜ãŸããã¯10ãªãã60åã®éã§ããã æ°Žãé€å»ããããšã¯ãããçŽç²ãªçæç©ããã
奜åçã§åŸãããšã«ã€ãªããã®ã§ãåæ¥ççç£ã«
ãšã€ãŠéèŠã§ãããæ°Žã¯åããéé¢ã€ãããŒãã
溶解ããŠããæ°Žäžæ··åæ§ææ©æº¶åªçžãåé¢ããã
ãšã«ãã€ãŠé€ãããã 溶åªäžã«æ®ã€ãŠããæ°Žã¯å šãŠãå ±æ²žèžçã«ã
ãããŸãã¯ã¢ã¬ããŠã©ãŒã·ãŒããŸãã¯ç¡æ°Žç¡«é žã
ããªãŠã ã®ãããªä¹Ÿç¥çšç¡æ°Žå¡©ã®ãããªä¹Ÿç¥å€ãš
æ¥è§Šãããããšã«ããé€ãããããããã®ä¹Ÿç¥å·¥
çšã®ãã¡ãå®éšå®€ã§ã®è£œé ã«ã¯æ¥è§Šä¹Ÿç¥å€ã奜ãŸ
ããããå·¥æ¥èŠæš¡ã®è£œé ã«ã¯å ±æ²žèžçã奜ãŸã
ãã 也ç¥ã€ãããŒãå¡©åºã次ã«ãžã±ãã³ãšåå¿ãã
ãŠåèšãªããµãžãã³ã圢æããããã€ãããŒãã
ãã³ãžã±ãã³ã¯å¥œãŸããã¯æº¶åªäžã«æº¶è§£ãããªã
ãã°ãªããªãã å ±æ²žèžçãäŸãã°ãã«ãšã³ãããã©ã¯ãããšã
ã¬ã³ãŸãã¯ããªã¯ãããšãã¬ã³ã䜿çšããããšã
奜ãŸãããããããäºãã«æ··åæ§ã®æº¶åªã§ããã°
åæåã«å¯Ÿããåã ã®æº¶åªã䜿çšããããšãå¯èœ
ã§ããããã«ãšã³ã奜ãŸããã éé¢ã€ãããŒããšãžã±ãã³ãšã®åå¿ã¯ãããªã¡
ãã«ã¢ãã³ãããã¯ããªãšãã«ã¢ãã³ãŸãã¯é ¢é ž
ã®ååšäžã§è¡ãªããããäžè¬çã«è§Šåªã¯åå¿äœã«
察ããŠ0.1ãªãã2.5ã¢ã«ïŒ ã®éã§äœ¿çšããããšã
ã§ãã奜ãŸããã¯ïŒãªãã10ã¢ã«ïŒ ãæã奜ãŸã
ãã¯2.5ãªããïŒã¢ã«ïŒ ã®éã§äœ¿çšãããã 䜿çšãããžã±ãã³ã®éã¯ãåèšéé¢ã€ãããŒã
ïŒã¢ã«åœããïŒãªãã1.05ã¢ã«ã§ããã倧éå°ã«
ããŠãå©ç¹ã¯åŸãããªãã åèšãªããµãžãã³åœ¢æã®åå¿ã¯çºç±åå¿ã§ã
ãããããåèšãªããµãžãã³ã¯çŽ40âã§å解ãå§
ããããšãç¥ãããŠããã®ã§ãåå¿å®¹åšã¯å·åŽã
ãå¿ èŠãããã容åšã35â以äžã«å·åŽããããšã«
ãããç¹ã«çµæžçã«æã䟡å€ã®é«ãïŒâã€ãœãã
ãã«âïŒâã¡ãã«âïŒâããããã·ããªããžã³ã®
å Žåã«ãé«çŽåºŠã®çæç©ãé«åçã§åŸããããã
ããã€ãŠããã®åå¿ã®æž©åºŠã¯ïŒãªãã60âã奜ãŸ
ããã¯15ãªãã35âã®éã§ãããåå¿ã¯ïŒæé以
å ã«å®äºããã äžèšå·¥çšïœïŒã«ãããŠã¯ãéé¢ã€ãããŒããšãž
ã±ãã³ãåå¿ããŠãªããµãžãã³ã圢æããããã
ã®ãªããµãžãã³ã®æ§é ãå³ã¡
ã«åºã¥ããçè«çèå¯ã«ãã確å®ãããããã®å
å¿ã¯ããžã±ãã³(2)ã®èŠªé»åæ§ã«ã«ããã«ççŽ åå
ãšã€ãããŒã(3)ã®æ±æ žæ§ã€ãããŒãçªçŽ ååãšã
åããåãããããŠã€ãããŒã(3)ã®èŠªé»åæ§ã€ã
ããŒãççŽ ååãšãžã±ãã³(2)ã®æ±æ žæ§ç°é žçŽ åå
ãšãåããåããããªïŒïŒïŒä»å ç©(1)ã®åœ¢æã«ã
ãéå§ãããããã®ä»å ç©(1)ã¯ããžã±ãã³å ã®ã«
ã«ããã«ççŽ ååãšç°é žçŽ ååãšã®çµåã圢æã
ãé»å察ãšãã€ãããŒãå ã®ã€ãããŒãççŽ åå
ãšã€ãããŒãçªçŽ ååãšã®äºéçµåã®äžæ¹ã®é»å
察ã®äžèšç¢å°ã§ç€ºãããããªåæã·ããã«ããå®
å®åããŠãç°å€äºéçµåãæãããªããµãžãã³(4)
ã圢æãããããŠæ¬¡ã«ç°å äºéçµåãæããç±å
åŠçã«ããå®å®ãªãªããµãžãã³(5)ã«ç°æ§åãã
ãã 次ã«åèšãªããµãžãã³ãã¢ã³ã¢ãã¢ã¬ã¹ãšåå¿
ãããŠåŒã§è¡šããããããããã·ããªããžã³ã
圢æããããå è€çã¯è¬åŠéèªç¬¬92å·»ã第886é
以äžïŒ1972幎ïŒã®ç¬¬889é ã«å€«ã ã®ãªããµãžãã³
ããšãã«ã¢ã«ã³ãŒã«äžã§ã¢ã³ã¢ãã¢æ°Žãšåå¿ãã
ãããšã«ããïŒâã€ãœãããã«âïŒâã¡ãã«âïŒ
ïŒ3HïŒâããªããã³ã®è£œé ã«ã€ããŠå ±åããŠããã
ããããªããã也ç¥ã¢ã³ã¢ãã¢ã¬ã¹ã®ããã®ææ©
溶åªã䜿çšããåå¿æ¹åŒã¯ãé«çŽåºŠçæç©ãé«å
çã§åŸãããšãå¯èœã«ãããã®çæç©ãæçµè£œå
ã«ããå Žåããã®æçµè£œåæ€æ»ãæ åœããæ¿åºæ©
é¢ã®è£œåèŠæºã«ããç·åçŽåºŠããã³è²çžèŠæ Œã«å
èŽããæçµè£œåãåŸãããšãå¯èœã«ããã ãã«ãšã³äžã§ã®åèšãªããµãžãã³ãšã¢ã³ã¢ãã¢
ã¬ã¹ãšã®åå¿ã¯ãïŒãªãã60âã奜ãŸããã¯ã15
ãªãã35âã®æž©åºŠã§è¡ãªãããïŒæé以å ã«å®äº
ãããåèšãªããµãžãã³ã®å€æã«ããçæããæ°Ž
ã¯å šãŠå ±æ²žèžçã«ããé€å»ããåŒã§è¡šãããã
ããããã·ããªããžã³ãåç98ïŒ ã§åŸããã¢ã³ã¢
ãã¢ã¬ã¹ã«ããäžèšå·¥çšïœïŒãªããïœïŒã«ããã
åèšãªããµãžãã³ããåŒã§è¡šãããããããã
ã·ããªããžã³ãžã®åå¿ã¯æ¬¡åŒã®ããã«é²è¡ãããš
æšå®ãããã æ¬çºæã«ãããŠåªããçæç©ãåŸãããã®ã¯ã
åèšãªããµãžãã³ããåŒã§è¡šãããããããã
ã·ããªããžã³ãžè³ãéã®äžéäœããæ°Žãé€å»ãã
ããšã«ããã äžèšã®ããã«ãæ¬çºæã®ç¹èš±è«æ±ãããæ¹æ³
ã¯ãåºçºç©è³ªãååã«èŠå®ãããããŠåå¿æ¡ä»¶ã
å«ããŠäžé£ã®åå¿ãååã«èŠå®ãããã®ã§ããã
åœæ¥è ã該æ¹æ³ãå®æœãããããŠã€ãããŒãå¡©é ž
å¡©ããïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâãããã
ã·ããªããžã³ãåŸãããšãã§ãããã®ã§ããã ãå®æœäŸããã³çºæã®å¹æã æ¬çºæã«ã€ããŠããªãã·ããªãžã³ã®åã§åæ¥äž
ç¥ãããŠããç£æ¥äžæãéèŠãªååç©ã§ããïŒâ
ã€ãœãããã«âïŒâã¡ãã«âïŒâããããã·ããª
ããžã³ã®è£œé äŸã«åºã¥ããŠããã«èª¬æãããå®æœ
äŸã«ã¯å¥œãŸããå®æœæ æ§ãããã³ããã«ä»£ãåŸã
å®æœæ æ§ã®äŸãèšèŒãããããããå®æœäŸã®æ¹æ³
ã¯ã€ãœãããã«ããªãã·ããªããžã³ãã ãã§ãªã
ä»ã®æ¬çºæã®ã¢ã«ãã«ããªããžã³ã«ãé©çšå¯èœã§
ãããäžèšã«äžè¬çã«èª¬æãããããŠäžèšã«å ·äœ
çã«äŸç€ºããæ¬çºæã®æ¹æ³ã«ãããŠãçš®ã ã®å€æ³
ããã³ä¿®æ£æ³ãå¯èœã§ããããã®å€æ³ããã³ä¿®æ£
æ³ãæ¬çºæã®ç¯å²ã«å±ããããšã¯èšããŸã§ããª
ããããã«å ·äœçå®æœæ æ§ã®èª¬æã§ãã以äžã®å®
æœäŸãæ¬çºæãéå®ãããã®ã§ãªãããšãèšããŸ
ã§ããªããå®æœäŸäžã枩床ã¯ææ°åäœã§è¡šããã
ãããŠã€ãããŒãå¡©é žå¡©ã®è¡šçŸã¯ç¹ã«ããšããã
ãªãéããäžèšåŒã§è¡šããããã€ãããŒãäžå¡©
é žå¡©ãæå³ããã å®æœäŸ ïŒ å®¹éïŒã®äžãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšããã³æ»ŽäžæŒæãèšçœ®ããããã©ã¹ã³
äžã«60ééïŒ ããªã¡ãã«ã¢ãã³æ°Žæº¶æ¶²452ïœ
ïŒ4.60ã¢ã«ïŒãæå ¥ããããã®æº¶æ¶²ã氷济ã§ïŒâ
ã«å·åŽãã次åŒïŒ ã§è¡šãããããšãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©
ãšå¡©åæ°ŽçŽ ãšã®æ··åç©199ïœã®ãã«ãšã³500mläžã®
溶液ïŒãšãã«ã€ãœããã«ã€ãããŒã1.00ã¢ã«ãã
ã³å¡©åæ°ŽçŽ 2.30ã¢ã«ïŒãåå¿æž©åºŠã10â以äžã«ä¿
æãããé床ã§æ·»å ãããæ·»å ã®å®äºåŸçžãåé¢
ããææ©çžãæ©æ¢°æ¹æè£ çœ®ã枩床èšãïŒãã€ãŒã
ã®å å¡«å¡ããŠãªãŒã¿ãŒãã©ããããã³å·åŽç®¡ãå
ãã容éïŒã®äžãå£äžžåºãã©ã¹ã³ãžç§»ãããæ··
åç©ãåžžå§ã§åŸã ã«å ç±ããããªã¡ãã«ã¢ãã³ã
åçž®ãããã«æåºããããã«ãšã³âæ°Žã®å ±æ²žæ··å
ç©ãåçž®ãããªããçåºç©ã®æ²žç¹ã110âã«éã
ããŸã§èžçãç¶ãããã€ãããŒãã®åçïŒå®¹åšäž
ã®ç©è³ªïŒã¯98.6ïŒ ã§ãããåŸããã溶液ã¯æ°Ž0.8
ã¢ã«ïŒ ãå«æããŠããã å®æœäŸ ïŒ å®¹é500mlã®äºãå£ãã©ã¹ã³ã«æ©æ¢°æ¹æè£ çœ®ã
枩床èšã滎äžæŒæããã³ãŠãªãŒã¿ãŒãã©ããä»ã
å·åŽç®¡ãèšçœ®ãããæ°Ž46ïœäžã®ããªã¡ãã«ã¢ãã³
56.4ïœïŒ0.96ã¢ã«ïŒã®æº¶æ¶²ãæå ¥ãããã®äžã«ãš
ãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©ãšå¡©åæ°ŽçŽ ãšã®
æ··åç©44.9ïœã®ããã©ã¯ãããšãã¬ã³80mläžã®æº¶
液ïŒãšãã«ã€ãœããã«ã€ãããŒã0.2ã¢ã«ããã³
å¡©åæ°ŽçŽ 0.6ã¢ã«ïŒãïŒåéãããŠæ»Žå ããã滎
å ã®é枩床ãâ12âãªããïŒâã«ä¿æãããé©å
å®äºåŸåå¿æ··åç©ã®çžãåé¢ããææ©çžäžã®æ°Žã
åžžå§ã§å ±æ²žèžçããŠé€å»ãããåŸããã也ç¥æº¶æ¶²
228ïœã¯ããšãã«ã€ãœããã«ã€ãããŒãã10.25é
éïŒ å«æãããã®åçã¯99.8ïŒ ã§ãã€ãã å®æœäŸ ïŒ æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³ãã©ã€
ã¢ã€ã¹âã¢ã»ãã³æµŽãåãã容éïŒã®äžãå£ã
ã©ã¹ã³äžã«æ°Ž500mläžã®çé žã«ãªãŠã 182.44ïœ
ïŒ1.32ã¢ã«ïŒãæå ¥ããããšãã«ã€ãœããã«ã€ã
ããŒãå¡©é žå¡©ãšå¡©åæ°ŽçŽ ã®æ··åç©105.7ïœïŒãšã
ã«ã€ãœããã«ã€ãããŒã0.5ã¢ã«ããã³å¡©åæ°ŽçŽ
1.32ã¢ã«ãå«æïŒããã«ãšã³200mlã§åžéããïŒ
åéãããŠæž©åºŠãâïŒâ以äžã«ä¿ã¡ãªãã滎å ã
ãããã®æº¶æ¶²ãâïŒâã§ããã«30åéæ¹æããã
ã®éã«æ°Ž300mlãå ããŠæ²æŸ±ããå¡©åã«ãªãŠã ã
溶解ãããçžãåé¢ããåŸãæ°Žçžããã«ãšã³50ml
ã§æœåºãããã«ãšã³çžãäžç·ã«ããŠïŒãã€ãŒãå
å¡«å¡ã䜿çšããŠå ±æ²žèžçã«ãã也ç¥ãããèžçã
ã©ã¹ã³äžã®æº¶æ¶²ã®ééã¯234.82ïœãšãã«ã€ãœãã
ã«ã€ãããŒã23.6ééïŒ ããã³1.1ã¢ã«ïŒ ãå«æ
ããŠããããšãã«ã€ãœããã«ã€ãããŒãã®åçã¯
96.4ïŒ ã§ãã€ãã å®æœäŸ ïŒ æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³ãã©ã€
ã¢ã€ã¹âã¢ã»ãã³æµŽã容éïŒã®äžãå£ãã©ã¹ã³
ã«èšçœ®ãããã¡ãã«ã€ãœããã«ã€ãããŒã0.523
ã¢ã«ããã³å¡©åæ°ŽçŽ 1.282ã¢ã«ãå«æããã¡ãã«
ã€ãœããã«ã€ãããŒãå¡©é žå¡©ãšå¡©åæ°ŽçŽ ã®æ··åç©
99.6ïœããã«ãšã³20mlãšæ··åããŠå·åŽãããåå¿
枩床ãïŒâ以äžã«ä¿ã¡ãªãã10åéãããŠããªã¡
ãã«ã¢ãã³ã®25ïŒ æ°Žæ§æº¶æ¶²606ïœïŒããªã¡ãã«ã¢
ãã³2.56ã¢ã«ïŒãæ·»å ããã 溶液ãå·åŽæµŽã䜿çšããã«ïŒåéæ¹æããåŸã
çžãåé¢ãããæ°Žçžããã«ãšã³50mlã¥ã€ã§ïŒåæœ
åºãããã«ãšã³çžãäžç·ã«ããããã«ãšã³çžã«å«
ãŸããããªã¡ãã«ã¢ãã³ããã³æ°ŽãïŒãã€ãŒãå
å¡«å¡ããã³ãã€ãŒã³âã¹ã¿ãŒã¯ïŒDeanâStarkïŒ
èžçãã©ããã䜿çšããŠ95mmHgã§å ±æ²žèžçããŠ
çåºãããããã€ãŒã³âã¹ã¿ãŒã¯ãã©ããäžã®æ°Ž
ãé€å»ããåŸãã«ãšã³çžããã©ã¹ã³ã«ãã©ããç¡«
é žãããªãŠã ïŒïœããã©ããã®åºã«æ·»å ãå床èž
çãéå§ããããã©ããäžã®çåããã©ã¹ã³äžã«
ãã©ãããåŸããã溶液ã®ééã¯265.06ïœã§ã¡ã
ã«ã€ãœããã«ã€ãããŒã20.6ééïŒ ããã³æ°Ž2.1
ã¢ã«ïŒ ãå«æããŠãããã¡ãã«ã€ãœããã«ã€ãã
ãŒãã®åçã¯99.7ïŒ ã§ãã€ãã å®æœäŸ ïŒ æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³æ°·æµŽã
åãã容éïŒã®äžãå£äžžåºãã©ã¹ã³äžã«ã25é
éïŒ æ°Žæ§ããªã¡ãã«ã¢ãã³971.61ïœïŒ4.11ã¢ã«ïŒ
ãæå ¥ããããã®æº¶æ¶²ãïŒâã«å·åŽãããšãã«ã€
ãœããã«ã€ãããŒã1.00ã¢ã«ããã³å¡©åæ°ŽçŽ 2.35
ã¢ã«ãå«æããããã«ãšã³äžã®43.6ééïŒ ãšãã«
ã€ãœããã«ã€ãããŒãå¡©é žå¡©æº¶æ¶²347.39ïœãïŒæ
é20åãããŠæ»Žå ãããã®éåå¿æž©åºŠïŒãïŒâã«
ä¿æããã滎å å®äºåŸæº¶æ¶²ãããã«15åéæ¹æ
ããçžãåé¢ãããæ°Žçžããã«ãšã³150mlã§æœåº
ããææ©çžãåããŠç¡æ°Žç¡«é žãããªãŠã äžã§ä¹Ÿç¥
åŸæ¿Ÿéãããæ¿ŸéåŸã®ç¡«é žãããªãŠã ããã«ãšã³
50mlã§æŽæµããã濟液ã®ééã¯413.57ïœããããš
ãã«ã€ãœããã«ã€ãããŒãã25.8ééïŒ å«æããŠ
ããïŒåç92.5ïŒ ïŒã溶液ãæžå§äžã«çœ®ããŠéå°
ã®ããªã¡ãã«ã¢ãã³ãé€ããåŸããã溶液ïŒã€ã
ããŒãã27.2ééïŒ å«æïŒãç¡æ°Žç¡«é žãã°ãã·ãŠ
ã äžã§ä¹Ÿç¥ããã å®æœäŸ ïŒ å®¹éïŒã®äžãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšããã³æ»ŽäžæŒæãèšçœ®ããããã®ãã©
ã¹ã³äžã«25ïŒ ããªã¡ãã«ã¢ãã³æ°Žæº¶æ¶²1189ïœ
ïŒ5.04ã¢ã«ïŒãæå ¥ããã溶液ãïŒãªãã10âã«
å·åŽããã¡ãã«ã€ãœããã«ã€ãããŒã1.0ã¢ã«ã
ãã³å¡©åæ°ŽçŽ 2.9ã¢ã«ãå«æããããã«ãšã³äžã®
48.7ééïŒ ã¡ãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©æº¶
液282.57ïœãšå¡©åã¡ãã¬ã³500mlã®æ··åç©ã10å
éãããŠæ»Žå ãããã®é枩床ãïŒã10âã«ä¿æã
ããçžãåé¢ããææ©çžãç¡æ°Žç¡«é žãã°ãã·ãŠã
äžã§ä¹Ÿç¥ããæ¿ŸéããŠåç100.9ïŒ ã§ã€ãããŒã
13.2ééïŒ ãå«æããç©è³ª772.15ïœãåŸãã溶åª
ãç空äžã§é€å»ããæ®æž£ïŒã€ãããŒãã53.4éé
ïŒ å«æïŒã4Aã¢ã¬ããŠã©ãŒã·ãŒãäžã«ä¿åããã å®æœäŸ ïŒ å®¹é250mlã®äžãå£äžžåºãã©ã¹ã³ã«æž©åºŠèšãã
ã°ããã€ãã¯ã¹ã¿ãŒã©ãŒã也ç¥ç®¡ããã³æ»ŽäžæŒæ
ãèšçœ®ããããã©ã¹ã³äžã«å®æœäŸïŒã§åŸã27.2é
éïŒ ãšãã«ã€ãœããã«ã€ãããŒãã®ãã«ãšã³æº¶æ¶²
42.0ïœïŒ0.099ã¢ã«ïŒããã«ãšã³70mlããã³ãã«
ãšã³äžã®7.61ééïŒ ããªã¡ãã«ã¢ãã³æº¶æ¶²7.15ïœ
ïŒ0.0092ã¢ã«ïŒãšãšãã«æå ¥ããããã®æ··åç©ã
氷济ã§ïŒâã«å·åŽãããã«ãšã³20mläžã®ãžã±ãã³
8.41ïœïŒ0.01ã¢ã«ïŒã®æº¶æ¶²ã12åéãããŠæ»Žå ã
ãããã®æ··åç©ãïŒåéæ¹æãã氷济ãé€å»ã
ãã15åéã§åå¿æž©åºŠã31âã«äžæãããããç¶
ããŠå€éšããå·åŽããŠ25âã«ããããžã±ãã³æ·»å
åŸããïŒæé20ååŸãåå¿æ··åç©ãïŒâã«å·åŽ
ããã¢ã³ã¢ãã¢ã¬ã¹ã2.5æéå¹ã蟌ã¿ãã®éã«
åå¿æ··åç©ã®æž©åºŠã宀枩ã«ãã©ããã次ãã§åå¿
æ··åç©ãå ±æ²žèžçã§æ°Žãé€ããªããïŒæé15åé
æµããã溶åªãç空ã§é€å»ããã€ãããŒãããã®
åç90.9ïŒ ããžã±ãã³ããã®åç89.6ïŒ ã§åºåœ¢ç©
4.72ïœïŒçŽç²ïŒâã€ãœãããã«âïŒâã¡ãã«âïŒ
âããããã·ããªããžã³ã92.6ééïŒ å«æïŒãåŸ
ãã äžèšå·¥çšã«ãããŠããšãã«ã€ãœããã«ã€ãããŒ
ããããªããµãžãã³ãçµãŠïŒâã€ãœãããã«âïŒ
âã¡ãã«âïŒâããããã·ããªããžã³ãåŸããã
ãã®ã§ããããã®ãªããµãžãã³ããã³ïŒâã€ãœã
ããã«âïŒâã¡ãã«âïŒâããããã·ããªããžã³
ã®æ§é ã¯ãåèšãããããªäžè¬çãªåå¿æ©æ§ã«åº
ã¥ããçè«çèå¯ã«ãã確å®ãããããã®åå¿æ©
æ§ãæ¬å®æœäŸã«ããŠã¯ããŠç€ºããšä»¥äžã®éãã§ã
ãã ãªãã以äžã®å®æœäŸã«ããããªããµãžãã³ãã
ã³æçµçæç©ã®æ§é ã®ç¢ºå®ãåæ§ã«ããŠè¡ããã
ããå®æœäŸïŒããã³10ã«ããããªããµãžãã³ã®æ§
é ã¯æ¬¡åŒïŒ ã§è¡šãããããã®ã§ããã å®æœäŸ ïŒ å®¹é250mlã®äžãå£ãã©ã¹ã³ã«ãã°ããã€ãã¯
ã¹ã¿ãŒã©ãŒã枩床èšã滎äžæŒæããã³ä¹Ÿç¥ç®¡ãèš
眮ããããã®ãã©ã¹ã³äžãžãã¡ãã«ã€ãœããã«ã€
ãããŒã0.1ã¢ã«ãå«æããå®æœäŸïŒããã®ã¡ã
ã«ã€ãœããã«ã€ãããŒãã®53.4ééïŒ ãã«ãšã³æº¶
液19.0ïœãè¿œå ã®ãã«ãšã³25mlããã³ããªã¡ãã«
ã¢ãã³0.01ã¢ã«ãå«æããããªã¡ãã«ã¢ãã³ã®
7.61ééïŒ ãã«ãšã³æº¶æ¶²7.73ïœãšäžç·ã«æå ¥ã
ãããã®æ··åç©ãïŒâã«å·åŽãããã«ãšã³25mläž
ã®ãžã±ãã³ïŒ8.41ïœã0.10ã¢ã«ïŒæº¶æ¶²ã12åéã
ããŠæ»Žå ããããžã±ãã³ã®æ»Žå ã®éã«æ°·æµŽãé€å»
ããåå¿æ··åç©ã®æž©åºŠã31âã«äžæãããã枩床
ã20ã30âã«ïŒæéä¿æããããã«ãšã³70mlãå
å¿ç©äžã«æ·»å ããå·åŽããªããæ··åç©äžã«ã¢ã³ã¢
ãã¢ãå¹ã蟌ãã ãã¢ã³ã¢ãã¢åŠçã®ïŒæé20å
åŸãåå¿æ··åç©ãæ°Žãé€å»ããªããïŒæé10åé
æµããã溶åªãç空äžã§é€å»ãã90.5ïŒ ã®åçã§
åºåœ¢ç©14.77ïœïŒïŒâã€ãœãããã«âïŒâã¡ãã«
âïŒâããããã·ããªããžã³ã92.6ééïŒ å«æïŒ
ãåŸãã å®æœäŸ ïŒ å®¹é250mlã®äžãå£ãã©ã¹ã³ã«æ©æ¢°æ¹æè£ çœ®ã
滎äžæŒæã枩床èšãã¬ã¹å°å ¥ç®¡ããã³ãŠãªãŒã¿ãŒ
ãã©ããã¥ãå·åŽç®¡ãèšçœ®ãããããªã¡ãã«ã¢ã
ã³è§Šåªã0.015ã¢ã«å«æããããã©ã¯ãããšãã¬
ã³85mläžã®ãšãã«ã€ãœããã«ã€ãããŒã17.25ïœ
ã®æº¶æ¶²ïŒãšãã«ã€ãœããã«ã€ãããŒãã0.15ã¢ã«
å«æïŒãæå ¥ãããã®äžã«ããã©ã¯ãããšãã¬ã³
15mläžã®ãžã±ãã³12.66ïœïŒ0.16ã¢ã«ïŒã®æº¶æ¶²ã
19åéãããŠæ»Žå ããã滎å äžæž©åºŠã16âã27â
ã«ä¿æãããã®åŸïŒæé25âã«ä¿æãããåå¿ç©
äžã«ã¢ã³ã¢ãã¢ã¬ã¹ãïŒæéå°å ¥ãïŒæž©åºŠ25âïŒã
åå¿ç©ãéæµæž©åºŠã«1.1æéä¿ã€ãŠïŒæçµæž©åºŠ120
âïŒçããæ°Žãšãšã¿ããŒã«ãé€å»ãããåå¿ç©ã
æ¿çž®ä¹ŸåºããŠãåç92.8ïŒ ã§ïŒâã€ãœãããã«â
ïŒâã¡ãã«âïŒâããããã·ããªããžã³ã91.4é
éïŒ å«æããåºåœ¢ç©23.0ïœãåŸãã å®æœäŸ 10 容é500mlã®äºãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšã滎äžæŒæããã³å¡©åã«ã«ã·ãŠã 也ç¥
管ãèšçœ®ããããã©ã¹ã³äžã«ã¡ãã«ã€ãœããã«ã€
ãããŒãã®14.2ééïŒ ããªã¯ãããšãã¬ã³æº¶æ¶²
116.55ïœïŒ0.164ã¢ã«ïŒããã³ããªã¡ãã«ã¢ãã³
ã®19.9ééïŒ ããªã¯ãããšãã¬ã³æº¶æ¶²4.86ïœ
ïŒ0.0164ã¢ã«ïŒãæå ¥ãããæ··åç©ã15âã«å·åŽ
ããããªã¯ãããšãã¬ã³40mläžã®ãžã±ãã³æº¶æ¶²
13.8ïœïŒ0.164ã¢ã«ïŒãïŒåéãããŠæ¥éã«åå¿
æ··åç©ã«å ããã枩床ãåŸã ã«30âã«äžæããã
æ··åç©ã宀枩ã§2.5æéæ¹æãããã¬ã¹åæ£çšã®
管ãèšçœ®ããåå¿æ··åç©äžã«ïŒæéã«ããã€ãŠã¢
ã³ã¢ãã¢ã¬ã¹ãå¹ã蟌ã¿ããã®é枩床ã25â以äž
ã«ä¿æããããã€ãŒã³âã¹ã¿ãŒã¯ãã©ããããã³
å·åŽç®¡ãèšçœ®ããæ··åç©ãå ±æ²žèžçã«ããæ°Žãé€
å»ããªããïŒæééæµãããç空äžã§æº¶åªãé€å»
ããåç85.6ïŒ ã§ïŒâã€ãœãããã«âïŒâã¡ãã«
âïŒâããããã·ããªããžã³ã86.2ééïŒ å«æã
ãåºåœ¢ç©24.58ïœãåŸãã å®æœäŸ 11 容é500mlã®äºãå£ãã©ã¹ã³ã«æ©æ¢°æ¹æè£ çœ®ã
滎äžæŒæãã¬ã¹å°å ¥ç®¡ã枩床èšããã³ãŠãªãŒã¿ãŒ
ãã©ããä»ãå·åŽç®¡ãèšçœ®ãããããªãšãã«ã¢ã
ã³è§Šåª1.01ïœïŒ0.01ã¢ã«ïŒãå«æãããã«ãšã³40
mläžã®ãšãã«ã€ãœããã«ã€ãããŒã11.5ïœïŒ0.1
ã¢ã«ïŒã®æº¶æ¶²ãæå ¥ãããã®æ··åç©äžã«ãã«ãšã³
25mläžã®ãžã±ãã³8.4ïœïŒ0.1ã¢ã«ïŒã®æº¶æ¶²ãïŒå
éãããŠæ»Žå ããã滎å ã®é枩床ã20ã29âã«ä¿
æãããã®åŸïŒæé26âã«ä¿æããã次ãã§ãã®
åå¿ç©äžã«ã¢ã³ã¢ãã¢ã¬ã¹ã2.5æéã«ããã€ãŠ
éãïŒæž©åºŠ26âïŒãåå¿ç©ãéæµæž©åºŠã§ïŒæéå
ç±ããŠïŒæçµæž©åºŠ110âïŒçããæ°Žããã³ãšã¿ã
ãŒã«ãé€å»ãããåå¿ç©ãæ¿çž®ä¹Ÿç¥ããåç44.8
ïŒ ã§ïŒâã€ãœãããã«âïŒâã¡ãã«âïŒâããã
ãã·ããªããžã³ã61.6ééïŒ å«æããåºåœ¢ç©
10.98ïœãåŸãã å®æœäŸ 12 æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³å¡©ãæ·»
å ãã氷济ãèšçœ®ãã容éïŒã®äžãå£ãã©ã¹ã³
ã«ãšãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©204.34ïœ
ïŒãšãã«ã€ãœããã«ã€ãããŒãïŒã¢ã«ããã³å¡©å
æ°ŽçŽ 2.4ã¢ã«ãå«æïŒããã³ãã«ãšã³300mlãæå ¥
ããã ãã®æº¶æ¶²ã«49.52ïŒ æ°Žæ§ããªã¡ãã«ã¢ãã³æº¶æ¶²
573ïœïŒ4.8ã¢ã«ïŒã25åéãããŠæ·»å ãããã®é
枩床ã11â以äžã«ä¿æãããçžãåé¢ããåŸãæ°Ž
çžããã«ãšã³100mlã§æœåºããæœåºæ¶²ããã«ãšã³
çžãšäžç·ã«ããããã«ãšã³çžäžã®éå°ã®ããªã¡ã
ã«ã¢ãã³ããã³æ°ŽãïŒãã€ãŒãå å¡«å¡ã䜿çšããŠ
å ±æ²žèžçã«ãã€ãŠé€å»ããã也ç¥ãã«ãšã³æº¶æ¶²ã®
ééã¯433.44ïœããããšãã«ã€ãœããã«ã€ãããŒ
ãã25.7ééïŒ ããã³æ°Žã0.25ã¢ã«ïŒ å«æããŠã
ãããšãã«ã€ãœããã«ã€ãããŒãã®åçã¯96.8ïŒ
ã§ãã€ãããã°ããã€ãã¯ã¹ã¿ãŒã©ãŒã枩床èšã
ãã€ãŒã³âã¹ã¿ãŒã¯èžçãã©ãããå·åŽç®¡ããã³
也ç¥ç®¡ãåãã容é250mlã®äžãå£ãã©ã¹ã³ã«ã
äžèšã§åŸããšãã«ã€ãœããã«ã€ãããŒãã®ãã«ãš
ã³æº¶æ¶²44.86ïœïŒ0.1ã¢ã«ïŒããã³ãžã±ãã³8.41ïœ
ïŒ0.1ã¢ã«ïŒãæå ¥ãããæ··åç©ãïŒâã«å·åŽãã
åŸããã«ãšã³äžã®20.07ééïŒ ããªã¡ãã«ã¢ãã³
溶液0.74ïœïŒ0.0025ã¢ã«ïŒãæ·»å ãããæž©åãªçº
ç±åå¿ãçãã枩床ã15åéã§ïŒâã«äžæããã
氷济ãé€å»ããŠåå¿æ··åç©ã宀枩ãŸã§æž©ãããå
å¿æ··åç©ãïŒæéæ¹æãããã«ãšã³25mlãæ·»å
ããã¢ã³ã¢ãã¢ã¬ã¹ã2.5æéå¹èŸŒã¿ããã®éæž©
床ã10ã24âã«ä¿æããã¢ã³ã¢ãã¢ã®å¹ã蟌ã¿ã
æ¢ããåå¿æ··åç©ãå ç±ããéæµããŠå ±æ²žèžçã«
ããæ°Žãé€å»ããã溶åªãèžçºãããŠèç¹161ã
170âã®æ·¡é»è²çµæ¶ã®ïŒâã€ãœãããã«âïŒâã¡
ãã«âïŒâããããã·ããªããžã³14.9ïœãåŸãã
åçã¯93.0ïŒ ã§ãã¬ã¹ã¯ãããã°ã©ãã€ãŒã«ãã
çŽåºŠã¯94.3ïŒ ã§ãã€ãã å®æœäŸ 13 æ¹æäžã®å®¹éïŒã®ãžã€ã±ããä»æš¹è槜ãäžå
容åšãšããŠå®éšå®€çšé£ç¶äžåè£ çœ®ãæ§æãããã
ã®å®¹åšäžã«FMIèšéãã³ãã«ãã€ãŠãšãã«ã€ãœ
ããã«ã€ãããŒãå¡©é žå¡©ããã«ãšã³ããã³æ°Žãé
å ¥ããããªã¡ãã«ã¢ãã³ïŒTMAïŒãããŒã¿ã¡ãŒ
ã¿ãŒãéããŠã¬ã¹ãšããŠåæ£ãããã容åšããã®
ãªãŒããŒãããŒã¯ãã«ã³ã¿ãŒãžãã³ãã§ç§»éãã
ãã®å Žã§çžãåé¢ããã ææ©çžãTMAâHClæœåºã®ããããã«ã³ã¿ãŒ
ããïŒïŒ4â³ããã»ã©ã€ã³ãµãã«ãºïŒProcelain
SaddlesïŒãã€ãæ°Žã§æºããã24â³ÃïŒïŒ4â³ã®ã«ã©
ã ãžéã€ããäžå容åšäžã«æåã«æå ¥ããéã¯ã
æ°Ž240mlããã³ãã«ãšã³132mlãšããããã10â以
äžã«å·åŽããããã®å®¹åšã«ïŒæéåœãããã«ãšã³
202ïœäžã®æº¶æ¶²ãšããŠãšãã«ã€ãœããã«ã€ãããŒ
ãHClïŒåæå€ïŒã€ãããŒã55.3ééïŒ ãHCl42.4
ééïŒ ïŒ208ïœãTMAïŒHClã«å¯ŸããŠ50ïŒ éå°
éïŒ214ïœãæ°Ž150ïœããã³ãã«ãšã³230ïœãäŸçµŠ
ããããã«ãšã³ããã³ãšãã«ã€ãœããã«ã€ãããŒ
ãHClïŒãã«ãšã³æº¶æ¶²äŸçµŠã©ã€ã³ïŒé 管ïŒã¯æ··å
çšïŒŽå管ã«ãã€ãŠä»ã®æåã®å ±éäŸçµŠã©ã€ã³ãšçµ
åããã枩床ã¯10ã20âã«ä¿ã€ãã容åšäžã®å®¹ç©
ã¯çŽ750mlã«å®ããããªãŒããŒãããŒã¯ãã«ã³ã¿
ãŒãžç§»ããïŒãªãŒããŒãããŒã©ã€ã³ã¯åäžãªææ©
溶åªâæ°Žæ··åç©ã確å®ã«åŸãããæš¹è槜ã®ã»ãŒäž
ã»ã©ã«ã€ãªãå¿ èŠããããïŒãæ°Žçžã¯ããªã¡ãã«ã¢
ãã³å埪ç°ã«ãã©ããïŒææ©çžã¯æŽæµã«ã©ã ã«é
ã€ããæŽæµæ°ŽïŒçŽ100ïœïŒã¯ïŒæéæ¯ã«äº€æããã
ãã®æŽæµã«ã©ã ã¯ãæŽæµæ°Žãäžå容åšã«å埪ç°ã
ããŠé£ç¶æäœã§ãããææ©çžããããæ³ã§ã®äžå
ã®éèšèŒããã®ãšåæ§ã«ããŠä¹Ÿç¥ããããšãã«ã€
ãœããã«ã€ãããŒãã®åçã¯95ã98ïŒ ã§ãã€ãã å®æœäŸ 14 容é250mlã®äžãå£äžžåºãã©ã¹ã³ã«ãã°ããã€
ãã¯ã¹ã¿ãŒã©ãŒã枩床èšããã³ä¹Ÿç¥ç®¡ãèšçœ®ã
ãããã©ã¹ã³äžã«ãžã±ãã³8.82ïœïŒ0.105ã¢ã«ïŒ
ããã³ãããªãŠã äžã®19.75ééïŒ ãšãã«ã€ãœã
ãã«ã€ãããŒã溶液58.22ïœïŒ0.1ã¢ã«ïŒãæå ¥ã
ãããã®æ··åç©ãæ¹æãã觊åªãšããŠæ°·é ¢é ž0.6
ïœïŒ0.01ã¢ã«ïŒãå ããã15ååŸã«åå¿ç©ã®æž©åºŠ
ã¯49âã«éãããã®æå€éšããã®å·åŽãéå§ã
ããæ··åç©ãããã«ïŒæéæ¹æããã¢ã³ã¢ãã¢ã¬
ã¹ãå°å ¥ãããã¢ã³ã¢ãã¢å°å ¥ã®ïŒæéåŸåå¿æ··
åç©ãïŒæéå ç±ãã溶åªãæžå§äžã§é€å»ããïŒ
âã€ãœãããã«âïŒâã¡ãã«âïŒâããããã·ã
ãªããžã³ã®åç70.1ïŒ ã§åºåœ¢ç©ïŒïŒâã€ãœããã
ã«âïŒâã¡ãã«âïŒâããããã·ããªããžã³ã
67.0ééïŒ å«æïŒ15.81ïœãåŸãã å®æœäŸ 15 容éïŒã®äºãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšããã³ä¹Ÿç¥ç®¡ãèšçœ®ããããã©ã¹ã³äž
ã«ãã«ãšã³äžã®ä¹Ÿç¥ãšãã«ã€ãœããã«ã€ãããŒã
881.64ïœïŒ1.5ã¢ã«ïŒããã³ãžã±ãã³132.5ïœ
ïŒ1.58ã¢ã«ïŒãæå ¥ãããæ··åç©ãïŒâã«å·åŽãã
ãã«ãšã³äžã®TMA溶液21.42ïœïŒ0.08ã¢ã«ïŒãæ
å ¥ãããåå¿æ··åç©ã®æž©åºŠãïŒæéã«ããã€ãŠ30
â以äžã«èª¿ç¯ãããé±æ²¹åŽåºè£ 眮ããã³ã¬ã¹åæ£
管ãèšçœ®ã也ç¥ç®¡ã¯åãå€ãããã¢ã³ã¢ãã¢ã¬ã¹
ãïŒæéã«ããã€ãŠåå¿æ··åç©äžã«å¹ã蟌ã¿ãã
ã®éåå¿æž©åºŠã30â以äžã«èª¿ç¯ããããã®æç¹ã§
ãã€ãŒã³âã¹ã¿ãŒã¯ãã©ããããã³å·åŽç®¡ãèšçœ®
ããã¢ã³ã¢ãã¢ã®å°å ¥ãåæ¢ãããåå¿æ··åç©ã
å ç±ããéæµããŠæ°Žããã³ãšã¿ããŒã«ãå ±æ²žèžç
ã§é€ããªããèžæ°æž©åºŠã108âã«éãããŸã§éæµ
ãç¶ãããåå¿æ··åç©ã宀枩ã«å·åŽããæ¿å¡©é ž
156ïœããã³æ°Ž200mlãæ·»å ãåŸãããæ··åç©ãæ¿
ããæ¹æãããçžãåé¢ããæ°Žçžã枩床èšãæ©æ¢°
æ¹æè£ çœ®ãå€éšå ç±è£ 眮ãåãã容éïŒã®äžã
å£ã®åºéšã«æåºå£ãæããåå¿å®¹åšã«ç§»ããã次
ãã§æ°Žçžãæ®çºæ§ææ©æåãå ±æ²žèžçã§é€ããªã
ãïŒæééæµãããæ··åç©ã宀枩ãŸã§å·åŽããã
ã®æº¶æ¶²ã«ïŒïŒïŒâãžã¯ãããšã¿ã³ïŒEDCïŒ1.600
mlããã³50ïŒ æ°Žé žåãããªãŠã 氎溶液126ïœã
倫ã å ãããæ··åç©ã60âã«å ç±ããçžãåé¢ã
ããæ°Žçžã60âã§EDC200mlã§åæœåºããææ©æœ
åºçžãäžç·ã«ããããã®ææ©çžããç空äžã§æº¶åª
ãé€å»ããè€è²åºåœ¢ç©209.8ïœãåŸãããã®åºåœ¢
ç©ã¯åæã«ããã°ãïŒâã€ãœãããã«âïŒâã¡ã
ã«âïŒâããããã·ããªããžã³ã99.2ééïŒ å«æ
ãããšãã«ã€ãœããã«ã€ãããŒãã«å¯Ÿããåçã¯
91.9ïŒ ã§ãã€ããæ°Žçžäžã«ãç®çç©ãåç0.72ïŒ
ã§ååšããŠããã
å¿ã¯ããžã±ãã³(2)ã®èŠªé»åæ§ã«ã«ããã«ççŽ åå
ãšã€ãããŒã(3)ã®æ±æ žæ§ã€ãããŒãçªçŽ ååãšã
åããåãããããŠã€ãããŒã(3)ã®èŠªé»åæ§ã€ã
ããŒãççŽ ååãšãžã±ãã³(2)ã®æ±æ žæ§ç°é žçŽ åå
ãšãåããåããããªïŒïŒïŒä»å ç©(1)ã®åœ¢æã«ã
ãéå§ãããããã®ä»å ç©(1)ã¯ããžã±ãã³å ã®ã«
ã«ããã«ççŽ ååãšç°é žçŽ ååãšã®çµåã圢æã
ãé»å察ãšãã€ãããŒãå ã®ã€ãããŒãççŽ åå
ãšã€ãããŒãçªçŽ ååãšã®äºéçµåã®äžæ¹ã®é»å
察ã®äžèšç¢å°ã§ç€ºãããããªåæã·ããã«ããå®
å®åããŠãç°å€äºéçµåãæãããªããµãžãã³(4)
ã圢æãããããŠæ¬¡ã«ç°å äºéçµåãæããç±å
åŠçã«ããå®å®ãªãªããµãžãã³(5)ã«ç°æ§åãã
ãã 次ã«åèšãªããµãžãã³ãã¢ã³ã¢ãã¢ã¬ã¹ãšåå¿
ãããŠåŒã§è¡šããããããããã·ããªããžã³ã
圢æããããå è€çã¯è¬åŠéèªç¬¬92å·»ã第886é
以äžïŒ1972幎ïŒã®ç¬¬889é ã«å€«ã ã®ãªããµãžãã³
ããšãã«ã¢ã«ã³ãŒã«äžã§ã¢ã³ã¢ãã¢æ°Žãšåå¿ãã
ãããšã«ããïŒâã€ãœãããã«âïŒâã¡ãã«âïŒ
ïŒ3HïŒâããªããã³ã®è£œé ã«ã€ããŠå ±åããŠããã
ããããªããã也ç¥ã¢ã³ã¢ãã¢ã¬ã¹ã®ããã®ææ©
溶åªã䜿çšããåå¿æ¹åŒã¯ãé«çŽåºŠçæç©ãé«å
çã§åŸãããšãå¯èœã«ãããã®çæç©ãæçµè£œå
ã«ããå Žåããã®æçµè£œåæ€æ»ãæ åœããæ¿åºæ©
é¢ã®è£œåèŠæºã«ããç·åçŽåºŠããã³è²çžèŠæ Œã«å
èŽããæçµè£œåãåŸãããšãå¯èœã«ããã ãã«ãšã³äžã§ã®åèšãªããµãžãã³ãšã¢ã³ã¢ãã¢
ã¬ã¹ãšã®åå¿ã¯ãïŒãªãã60âã奜ãŸããã¯ã15
ãªãã35âã®æž©åºŠã§è¡ãªãããïŒæé以å ã«å®äº
ãããåèšãªããµãžãã³ã®å€æã«ããçæããæ°Ž
ã¯å šãŠå ±æ²žèžçã«ããé€å»ããåŒã§è¡šãããã
ããããã·ããªããžã³ãåç98ïŒ ã§åŸããã¢ã³ã¢
ãã¢ã¬ã¹ã«ããäžèšå·¥çšïœïŒãªããïœïŒã«ããã
åèšãªããµãžãã³ããåŒã§è¡šãããããããã
ã·ããªããžã³ãžã®åå¿ã¯æ¬¡åŒã®ããã«é²è¡ãããš
æšå®ãããã æ¬çºæã«ãããŠåªããçæç©ãåŸãããã®ã¯ã
åèšãªããµãžãã³ããåŒã§è¡šãããããããã
ã·ããªããžã³ãžè³ãéã®äžéäœããæ°Žãé€å»ãã
ããšã«ããã äžèšã®ããã«ãæ¬çºæã®ç¹èš±è«æ±ãããæ¹æ³
ã¯ãåºçºç©è³ªãååã«èŠå®ãããããŠåå¿æ¡ä»¶ã
å«ããŠäžé£ã®åå¿ãååã«èŠå®ãããã®ã§ããã
åœæ¥è ã該æ¹æ³ãå®æœãããããŠã€ãããŒãå¡©é ž
å¡©ããïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâãããã
ã·ããªããžã³ãåŸãããšãã§ãããã®ã§ããã ãå®æœäŸããã³çºæã®å¹æã æ¬çºæã«ã€ããŠããªãã·ããªãžã³ã®åã§åæ¥äž
ç¥ãããŠããç£æ¥äžæãéèŠãªååç©ã§ããïŒâ
ã€ãœãããã«âïŒâã¡ãã«âïŒâããããã·ããª
ããžã³ã®è£œé äŸã«åºã¥ããŠããã«èª¬æãããå®æœ
äŸã«ã¯å¥œãŸããå®æœæ æ§ãããã³ããã«ä»£ãåŸã
å®æœæ æ§ã®äŸãèšèŒãããããããå®æœäŸã®æ¹æ³
ã¯ã€ãœãããã«ããªãã·ããªããžã³ãã ãã§ãªã
ä»ã®æ¬çºæã®ã¢ã«ãã«ããªããžã³ã«ãé©çšå¯èœã§
ãããäžèšã«äžè¬çã«èª¬æãããããŠäžèšã«å ·äœ
çã«äŸç€ºããæ¬çºæã®æ¹æ³ã«ãããŠãçš®ã ã®å€æ³
ããã³ä¿®æ£æ³ãå¯èœã§ããããã®å€æ³ããã³ä¿®æ£
æ³ãæ¬çºæã®ç¯å²ã«å±ããããšã¯èšããŸã§ããª
ããããã«å ·äœçå®æœæ æ§ã®èª¬æã§ãã以äžã®å®
æœäŸãæ¬çºæãéå®ãããã®ã§ãªãããšãèšããŸ
ã§ããªããå®æœäŸäžã枩床ã¯ææ°åäœã§è¡šããã
ãããŠã€ãããŒãå¡©é žå¡©ã®è¡šçŸã¯ç¹ã«ããšããã
ãªãéããäžèšåŒã§è¡šããããã€ãããŒãäžå¡©
é žå¡©ãæå³ããã å®æœäŸ ïŒ å®¹éïŒã®äžãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšããã³æ»ŽäžæŒæãèšçœ®ããããã©ã¹ã³
äžã«60ééïŒ ããªã¡ãã«ã¢ãã³æ°Žæº¶æ¶²452ïœ
ïŒ4.60ã¢ã«ïŒãæå ¥ããããã®æº¶æ¶²ã氷济ã§ïŒâ
ã«å·åŽãã次åŒïŒ ã§è¡šãããããšãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©
ãšå¡©åæ°ŽçŽ ãšã®æ··åç©199ïœã®ãã«ãšã³500mläžã®
溶液ïŒãšãã«ã€ãœããã«ã€ãããŒã1.00ã¢ã«ãã
ã³å¡©åæ°ŽçŽ 2.30ã¢ã«ïŒãåå¿æž©åºŠã10â以äžã«ä¿
æãããé床ã§æ·»å ãããæ·»å ã®å®äºåŸçžãåé¢
ããææ©çžãæ©æ¢°æ¹æè£ çœ®ã枩床èšãïŒãã€ãŒã
ã®å å¡«å¡ããŠãªãŒã¿ãŒãã©ããããã³å·åŽç®¡ãå
ãã容éïŒã®äžãå£äžžåºãã©ã¹ã³ãžç§»ãããæ··
åç©ãåžžå§ã§åŸã ã«å ç±ããããªã¡ãã«ã¢ãã³ã
åçž®ãããã«æåºããããã«ãšã³âæ°Žã®å ±æ²žæ··å
ç©ãåçž®ãããªããçåºç©ã®æ²žç¹ã110âã«éã
ããŸã§èžçãç¶ãããã€ãããŒãã®åçïŒå®¹åšäž
ã®ç©è³ªïŒã¯98.6ïŒ ã§ãããåŸããã溶液ã¯æ°Ž0.8
ã¢ã«ïŒ ãå«æããŠããã å®æœäŸ ïŒ å®¹é500mlã®äºãå£ãã©ã¹ã³ã«æ©æ¢°æ¹æè£ çœ®ã
枩床èšã滎äžæŒæããã³ãŠãªãŒã¿ãŒãã©ããä»ã
å·åŽç®¡ãèšçœ®ãããæ°Ž46ïœäžã®ããªã¡ãã«ã¢ãã³
56.4ïœïŒ0.96ã¢ã«ïŒã®æº¶æ¶²ãæå ¥ãããã®äžã«ãš
ãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©ãšå¡©åæ°ŽçŽ ãšã®
æ··åç©44.9ïœã®ããã©ã¯ãããšãã¬ã³80mläžã®æº¶
液ïŒãšãã«ã€ãœããã«ã€ãããŒã0.2ã¢ã«ããã³
å¡©åæ°ŽçŽ 0.6ã¢ã«ïŒãïŒåéãããŠæ»Žå ããã滎
å ã®é枩床ãâ12âãªããïŒâã«ä¿æãããé©å
å®äºåŸåå¿æ··åç©ã®çžãåé¢ããææ©çžäžã®æ°Žã
åžžå§ã§å ±æ²žèžçããŠé€å»ãããåŸããã也ç¥æº¶æ¶²
228ïœã¯ããšãã«ã€ãœããã«ã€ãããŒãã10.25é
éïŒ å«æãããã®åçã¯99.8ïŒ ã§ãã€ãã å®æœäŸ ïŒ æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³ãã©ã€
ã¢ã€ã¹âã¢ã»ãã³æµŽãåãã容éïŒã®äžãå£ã
ã©ã¹ã³äžã«æ°Ž500mläžã®çé žã«ãªãŠã 182.44ïœ
ïŒ1.32ã¢ã«ïŒãæå ¥ããããšãã«ã€ãœããã«ã€ã
ããŒãå¡©é žå¡©ãšå¡©åæ°ŽçŽ ã®æ··åç©105.7ïœïŒãšã
ã«ã€ãœããã«ã€ãããŒã0.5ã¢ã«ããã³å¡©åæ°ŽçŽ
1.32ã¢ã«ãå«æïŒããã«ãšã³200mlã§åžéããïŒ
åéãããŠæž©åºŠãâïŒâ以äžã«ä¿ã¡ãªãã滎å ã
ãããã®æº¶æ¶²ãâïŒâã§ããã«30åéæ¹æããã
ã®éã«æ°Ž300mlãå ããŠæ²æŸ±ããå¡©åã«ãªãŠã ã
溶解ãããçžãåé¢ããåŸãæ°Žçžããã«ãšã³50ml
ã§æœåºãããã«ãšã³çžãäžç·ã«ããŠïŒãã€ãŒãå
å¡«å¡ã䜿çšããŠå ±æ²žèžçã«ãã也ç¥ãããèžçã
ã©ã¹ã³äžã®æº¶æ¶²ã®ééã¯234.82ïœãšãã«ã€ãœãã
ã«ã€ãããŒã23.6ééïŒ ããã³1.1ã¢ã«ïŒ ãå«æ
ããŠããããšãã«ã€ãœããã«ã€ãããŒãã®åçã¯
96.4ïŒ ã§ãã€ãã å®æœäŸ ïŒ æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³ãã©ã€
ã¢ã€ã¹âã¢ã»ãã³æµŽã容éïŒã®äžãå£ãã©ã¹ã³
ã«èšçœ®ãããã¡ãã«ã€ãœããã«ã€ãããŒã0.523
ã¢ã«ããã³å¡©åæ°ŽçŽ 1.282ã¢ã«ãå«æããã¡ãã«
ã€ãœããã«ã€ãããŒãå¡©é žå¡©ãšå¡©åæ°ŽçŽ ã®æ··åç©
99.6ïœããã«ãšã³20mlãšæ··åããŠå·åŽãããåå¿
枩床ãïŒâ以äžã«ä¿ã¡ãªãã10åéãããŠããªã¡
ãã«ã¢ãã³ã®25ïŒ æ°Žæ§æº¶æ¶²606ïœïŒããªã¡ãã«ã¢
ãã³2.56ã¢ã«ïŒãæ·»å ããã 溶液ãå·åŽæµŽã䜿çšããã«ïŒåéæ¹æããåŸã
çžãåé¢ãããæ°Žçžããã«ãšã³50mlã¥ã€ã§ïŒåæœ
åºãããã«ãšã³çžãäžç·ã«ããããã«ãšã³çžã«å«
ãŸããããªã¡ãã«ã¢ãã³ããã³æ°ŽãïŒãã€ãŒãå
å¡«å¡ããã³ãã€ãŒã³âã¹ã¿ãŒã¯ïŒDeanâStarkïŒ
èžçãã©ããã䜿çšããŠ95mmHgã§å ±æ²žèžçããŠ
çåºãããããã€ãŒã³âã¹ã¿ãŒã¯ãã©ããäžã®æ°Ž
ãé€å»ããåŸãã«ãšã³çžããã©ã¹ã³ã«ãã©ããç¡«
é žãããªãŠã ïŒïœããã©ããã®åºã«æ·»å ãå床èž
çãéå§ããããã©ããäžã®çåããã©ã¹ã³äžã«
ãã©ãããåŸããã溶液ã®ééã¯265.06ïœã§ã¡ã
ã«ã€ãœããã«ã€ãããŒã20.6ééïŒ ããã³æ°Ž2.1
ã¢ã«ïŒ ãå«æããŠãããã¡ãã«ã€ãœããã«ã€ãã
ãŒãã®åçã¯99.7ïŒ ã§ãã€ãã å®æœäŸ ïŒ æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³æ°·æµŽã
åãã容éïŒã®äžãå£äžžåºãã©ã¹ã³äžã«ã25é
éïŒ æ°Žæ§ããªã¡ãã«ã¢ãã³971.61ïœïŒ4.11ã¢ã«ïŒ
ãæå ¥ããããã®æº¶æ¶²ãïŒâã«å·åŽãããšãã«ã€
ãœããã«ã€ãããŒã1.00ã¢ã«ããã³å¡©åæ°ŽçŽ 2.35
ã¢ã«ãå«æããããã«ãšã³äžã®43.6ééïŒ ãšãã«
ã€ãœããã«ã€ãããŒãå¡©é žå¡©æº¶æ¶²347.39ïœãïŒæ
é20åãããŠæ»Žå ãããã®éåå¿æž©åºŠïŒãïŒâã«
ä¿æããã滎å å®äºåŸæº¶æ¶²ãããã«15åéæ¹æ
ããçžãåé¢ãããæ°Žçžããã«ãšã³150mlã§æœåº
ããææ©çžãåããŠç¡æ°Žç¡«é žãããªãŠã äžã§ä¹Ÿç¥
åŸæ¿Ÿéãããæ¿ŸéåŸã®ç¡«é žãããªãŠã ããã«ãšã³
50mlã§æŽæµããã濟液ã®ééã¯413.57ïœããããš
ãã«ã€ãœããã«ã€ãããŒãã25.8ééïŒ å«æããŠ
ããïŒåç92.5ïŒ ïŒã溶液ãæžå§äžã«çœ®ããŠéå°
ã®ããªã¡ãã«ã¢ãã³ãé€ããåŸããã溶液ïŒã€ã
ããŒãã27.2ééïŒ å«æïŒãç¡æ°Žç¡«é žãã°ãã·ãŠ
ã äžã§ä¹Ÿç¥ããã å®æœäŸ ïŒ å®¹éïŒã®äžãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšããã³æ»ŽäžæŒæãèšçœ®ããããã®ãã©
ã¹ã³äžã«25ïŒ ããªã¡ãã«ã¢ãã³æ°Žæº¶æ¶²1189ïœ
ïŒ5.04ã¢ã«ïŒãæå ¥ããã溶液ãïŒãªãã10âã«
å·åŽããã¡ãã«ã€ãœããã«ã€ãããŒã1.0ã¢ã«ã
ãã³å¡©åæ°ŽçŽ 2.9ã¢ã«ãå«æããããã«ãšã³äžã®
48.7ééïŒ ã¡ãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©æº¶
液282.57ïœãšå¡©åã¡ãã¬ã³500mlã®æ··åç©ã10å
éãããŠæ»Žå ãããã®é枩床ãïŒã10âã«ä¿æã
ããçžãåé¢ããææ©çžãç¡æ°Žç¡«é žãã°ãã·ãŠã
äžã§ä¹Ÿç¥ããæ¿ŸéããŠåç100.9ïŒ ã§ã€ãããŒã
13.2ééïŒ ãå«æããç©è³ª772.15ïœãåŸãã溶åª
ãç空äžã§é€å»ããæ®æž£ïŒã€ãããŒãã53.4éé
ïŒ å«æïŒã4Aã¢ã¬ããŠã©ãŒã·ãŒãäžã«ä¿åããã å®æœäŸ ïŒ å®¹é250mlã®äžãå£äžžåºãã©ã¹ã³ã«æž©åºŠèšãã
ã°ããã€ãã¯ã¹ã¿ãŒã©ãŒã也ç¥ç®¡ããã³æ»ŽäžæŒæ
ãèšçœ®ããããã©ã¹ã³äžã«å®æœäŸïŒã§åŸã27.2é
éïŒ ãšãã«ã€ãœããã«ã€ãããŒãã®ãã«ãšã³æº¶æ¶²
42.0ïœïŒ0.099ã¢ã«ïŒããã«ãšã³70mlããã³ãã«
ãšã³äžã®7.61ééïŒ ããªã¡ãã«ã¢ãã³æº¶æ¶²7.15ïœ
ïŒ0.0092ã¢ã«ïŒãšãšãã«æå ¥ããããã®æ··åç©ã
氷济ã§ïŒâã«å·åŽãããã«ãšã³20mläžã®ãžã±ãã³
8.41ïœïŒ0.01ã¢ã«ïŒã®æº¶æ¶²ã12åéãããŠæ»Žå ã
ãããã®æ··åç©ãïŒåéæ¹æãã氷济ãé€å»ã
ãã15åéã§åå¿æž©åºŠã31âã«äžæãããããç¶
ããŠå€éšããå·åŽããŠ25âã«ããããžã±ãã³æ·»å
åŸããïŒæé20ååŸãåå¿æ··åç©ãïŒâã«å·åŽ
ããã¢ã³ã¢ãã¢ã¬ã¹ã2.5æéå¹ã蟌ã¿ãã®éã«
åå¿æ··åç©ã®æž©åºŠã宀枩ã«ãã©ããã次ãã§åå¿
æ··åç©ãå ±æ²žèžçã§æ°Žãé€ããªããïŒæé15åé
æµããã溶åªãç空ã§é€å»ããã€ãããŒãããã®
åç90.9ïŒ ããžã±ãã³ããã®åç89.6ïŒ ã§åºåœ¢ç©
4.72ïœïŒçŽç²ïŒâã€ãœãããã«âïŒâã¡ãã«âïŒ
âããããã·ããªããžã³ã92.6ééïŒ å«æïŒãåŸ
ãã äžèšå·¥çšã«ãããŠããšãã«ã€ãœããã«ã€ãããŒ
ããããªããµãžãã³ãçµãŠïŒâã€ãœãããã«âïŒ
âã¡ãã«âïŒâããããã·ããªããžã³ãåŸããã
ãã®ã§ããããã®ãªããµãžãã³ããã³ïŒâã€ãœã
ããã«âïŒâã¡ãã«âïŒâããããã·ããªããžã³
ã®æ§é ã¯ãåèšãããããªäžè¬çãªåå¿æ©æ§ã«åº
ã¥ããçè«çèå¯ã«ãã確å®ãããããã®åå¿æ©
æ§ãæ¬å®æœäŸã«ããŠã¯ããŠç€ºããšä»¥äžã®éãã§ã
ãã ãªãã以äžã®å®æœäŸã«ããããªããµãžãã³ãã
ã³æçµçæç©ã®æ§é ã®ç¢ºå®ãåæ§ã«ããŠè¡ããã
ããå®æœäŸïŒããã³10ã«ããããªããµãžãã³ã®æ§
é ã¯æ¬¡åŒïŒ ã§è¡šãããããã®ã§ããã å®æœäŸ ïŒ å®¹é250mlã®äžãå£ãã©ã¹ã³ã«ãã°ããã€ãã¯
ã¹ã¿ãŒã©ãŒã枩床èšã滎äžæŒæããã³ä¹Ÿç¥ç®¡ãèš
眮ããããã®ãã©ã¹ã³äžãžãã¡ãã«ã€ãœããã«ã€
ãããŒã0.1ã¢ã«ãå«æããå®æœäŸïŒããã®ã¡ã
ã«ã€ãœããã«ã€ãããŒãã®53.4ééïŒ ãã«ãšã³æº¶
液19.0ïœãè¿œå ã®ãã«ãšã³25mlããã³ããªã¡ãã«
ã¢ãã³0.01ã¢ã«ãå«æããããªã¡ãã«ã¢ãã³ã®
7.61ééïŒ ãã«ãšã³æº¶æ¶²7.73ïœãšäžç·ã«æå ¥ã
ãããã®æ··åç©ãïŒâã«å·åŽãããã«ãšã³25mläž
ã®ãžã±ãã³ïŒ8.41ïœã0.10ã¢ã«ïŒæº¶æ¶²ã12åéã
ããŠæ»Žå ããããžã±ãã³ã®æ»Žå ã®éã«æ°·æµŽãé€å»
ããåå¿æ··åç©ã®æž©åºŠã31âã«äžæãããã枩床
ã20ã30âã«ïŒæéä¿æããããã«ãšã³70mlãå
å¿ç©äžã«æ·»å ããå·åŽããªããæ··åç©äžã«ã¢ã³ã¢
ãã¢ãå¹ã蟌ãã ãã¢ã³ã¢ãã¢åŠçã®ïŒæé20å
åŸãåå¿æ··åç©ãæ°Žãé€å»ããªããïŒæé10åé
æµããã溶åªãç空äžã§é€å»ãã90.5ïŒ ã®åçã§
åºåœ¢ç©14.77ïœïŒïŒâã€ãœãããã«âïŒâã¡ãã«
âïŒâããããã·ããªããžã³ã92.6ééïŒ å«æïŒ
ãåŸãã å®æœäŸ ïŒ å®¹é250mlã®äžãå£ãã©ã¹ã³ã«æ©æ¢°æ¹æè£ çœ®ã
滎äžæŒæã枩床èšãã¬ã¹å°å ¥ç®¡ããã³ãŠãªãŒã¿ãŒ
ãã©ããã¥ãå·åŽç®¡ãèšçœ®ãããããªã¡ãã«ã¢ã
ã³è§Šåªã0.015ã¢ã«å«æããããã©ã¯ãããšãã¬
ã³85mläžã®ãšãã«ã€ãœããã«ã€ãããŒã17.25ïœ
ã®æº¶æ¶²ïŒãšãã«ã€ãœããã«ã€ãããŒãã0.15ã¢ã«
å«æïŒãæå ¥ãããã®äžã«ããã©ã¯ãããšãã¬ã³
15mläžã®ãžã±ãã³12.66ïœïŒ0.16ã¢ã«ïŒã®æº¶æ¶²ã
19åéãããŠæ»Žå ããã滎å äžæž©åºŠã16âã27â
ã«ä¿æãããã®åŸïŒæé25âã«ä¿æãããåå¿ç©
äžã«ã¢ã³ã¢ãã¢ã¬ã¹ãïŒæéå°å ¥ãïŒæž©åºŠ25âïŒã
åå¿ç©ãéæµæž©åºŠã«1.1æéä¿ã€ãŠïŒæçµæž©åºŠ120
âïŒçããæ°Žãšãšã¿ããŒã«ãé€å»ãããåå¿ç©ã
æ¿çž®ä¹ŸåºããŠãåç92.8ïŒ ã§ïŒâã€ãœãããã«â
ïŒâã¡ãã«âïŒâããããã·ããªããžã³ã91.4é
éïŒ å«æããåºåœ¢ç©23.0ïœãåŸãã å®æœäŸ 10 容é500mlã®äºãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšã滎äžæŒæããã³å¡©åã«ã«ã·ãŠã 也ç¥
管ãèšçœ®ããããã©ã¹ã³äžã«ã¡ãã«ã€ãœããã«ã€
ãããŒãã®14.2ééïŒ ããªã¯ãããšãã¬ã³æº¶æ¶²
116.55ïœïŒ0.164ã¢ã«ïŒããã³ããªã¡ãã«ã¢ãã³
ã®19.9ééïŒ ããªã¯ãããšãã¬ã³æº¶æ¶²4.86ïœ
ïŒ0.0164ã¢ã«ïŒãæå ¥ãããæ··åç©ã15âã«å·åŽ
ããããªã¯ãããšãã¬ã³40mläžã®ãžã±ãã³æº¶æ¶²
13.8ïœïŒ0.164ã¢ã«ïŒãïŒåéãããŠæ¥éã«åå¿
æ··åç©ã«å ããã枩床ãåŸã ã«30âã«äžæããã
æ··åç©ã宀枩ã§2.5æéæ¹æãããã¬ã¹åæ£çšã®
管ãèšçœ®ããåå¿æ··åç©äžã«ïŒæéã«ããã€ãŠã¢
ã³ã¢ãã¢ã¬ã¹ãå¹ã蟌ã¿ããã®é枩床ã25â以äž
ã«ä¿æããããã€ãŒã³âã¹ã¿ãŒã¯ãã©ããããã³
å·åŽç®¡ãèšçœ®ããæ··åç©ãå ±æ²žèžçã«ããæ°Žãé€
å»ããªããïŒæééæµãããç空äžã§æº¶åªãé€å»
ããåç85.6ïŒ ã§ïŒâã€ãœãããã«âïŒâã¡ãã«
âïŒâããããã·ããªããžã³ã86.2ééïŒ å«æã
ãåºåœ¢ç©24.58ïœãåŸãã å®æœäŸ 11 容é500mlã®äºãå£ãã©ã¹ã³ã«æ©æ¢°æ¹æè£ çœ®ã
滎äžæŒæãã¬ã¹å°å ¥ç®¡ã枩床èšããã³ãŠãªãŒã¿ãŒ
ãã©ããä»ãå·åŽç®¡ãèšçœ®ãããããªãšãã«ã¢ã
ã³è§Šåª1.01ïœïŒ0.01ã¢ã«ïŒãå«æãããã«ãšã³40
mläžã®ãšãã«ã€ãœããã«ã€ãããŒã11.5ïœïŒ0.1
ã¢ã«ïŒã®æº¶æ¶²ãæå ¥ãããã®æ··åç©äžã«ãã«ãšã³
25mläžã®ãžã±ãã³8.4ïœïŒ0.1ã¢ã«ïŒã®æº¶æ¶²ãïŒå
éãããŠæ»Žå ããã滎å ã®é枩床ã20ã29âã«ä¿
æãããã®åŸïŒæé26âã«ä¿æããã次ãã§ãã®
åå¿ç©äžã«ã¢ã³ã¢ãã¢ã¬ã¹ã2.5æéã«ããã€ãŠ
éãïŒæž©åºŠ26âïŒãåå¿ç©ãéæµæž©åºŠã§ïŒæéå
ç±ããŠïŒæçµæž©åºŠ110âïŒçããæ°Žããã³ãšã¿ã
ãŒã«ãé€å»ãããåå¿ç©ãæ¿çž®ä¹Ÿç¥ããåç44.8
ïŒ ã§ïŒâã€ãœãããã«âïŒâã¡ãã«âïŒâããã
ãã·ããªããžã³ã61.6ééïŒ å«æããåºåœ¢ç©
10.98ïœãåŸãã å®æœäŸ 12 æ©æ¢°æ¹æè£ çœ®ã枩床èšã滎äžæŒæããã³å¡©ãæ·»
å ãã氷济ãèšçœ®ãã容éïŒã®äžãå£ãã©ã¹ã³
ã«ãšãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©204.34ïœ
ïŒãšãã«ã€ãœããã«ã€ãããŒãïŒã¢ã«ããã³å¡©å
æ°ŽçŽ 2.4ã¢ã«ãå«æïŒããã³ãã«ãšã³300mlãæå ¥
ããã ãã®æº¶æ¶²ã«49.52ïŒ æ°Žæ§ããªã¡ãã«ã¢ãã³æº¶æ¶²
573ïœïŒ4.8ã¢ã«ïŒã25åéãããŠæ·»å ãããã®é
枩床ã11â以äžã«ä¿æãããçžãåé¢ããåŸãæ°Ž
çžããã«ãšã³100mlã§æœåºããæœåºæ¶²ããã«ãšã³
çžãšäžç·ã«ããããã«ãšã³çžäžã®éå°ã®ããªã¡ã
ã«ã¢ãã³ããã³æ°ŽãïŒãã€ãŒãå å¡«å¡ã䜿çšããŠ
å ±æ²žèžçã«ãã€ãŠé€å»ããã也ç¥ãã«ãšã³æº¶æ¶²ã®
ééã¯433.44ïœããããšãã«ã€ãœããã«ã€ãããŒ
ãã25.7ééïŒ ããã³æ°Žã0.25ã¢ã«ïŒ å«æããŠã
ãããšãã«ã€ãœããã«ã€ãããŒãã®åçã¯96.8ïŒ
ã§ãã€ãããã°ããã€ãã¯ã¹ã¿ãŒã©ãŒã枩床èšã
ãã€ãŒã³âã¹ã¿ãŒã¯èžçãã©ãããå·åŽç®¡ããã³
也ç¥ç®¡ãåãã容é250mlã®äžãå£ãã©ã¹ã³ã«ã
äžèšã§åŸããšãã«ã€ãœããã«ã€ãããŒãã®ãã«ãš
ã³æº¶æ¶²44.86ïœïŒ0.1ã¢ã«ïŒããã³ãžã±ãã³8.41ïœ
ïŒ0.1ã¢ã«ïŒãæå ¥ãããæ··åç©ãïŒâã«å·åŽãã
åŸããã«ãšã³äžã®20.07ééïŒ ããªã¡ãã«ã¢ãã³
溶液0.74ïœïŒ0.0025ã¢ã«ïŒãæ·»å ãããæž©åãªçº
ç±åå¿ãçãã枩床ã15åéã§ïŒâã«äžæããã
氷济ãé€å»ããŠåå¿æ··åç©ã宀枩ãŸã§æž©ãããå
å¿æ··åç©ãïŒæéæ¹æãããã«ãšã³25mlãæ·»å
ããã¢ã³ã¢ãã¢ã¬ã¹ã2.5æéå¹èŸŒã¿ããã®éæž©
床ã10ã24âã«ä¿æããã¢ã³ã¢ãã¢ã®å¹ã蟌ã¿ã
æ¢ããåå¿æ··åç©ãå ç±ããéæµããŠå ±æ²žèžçã«
ããæ°Žãé€å»ããã溶åªãèžçºãããŠèç¹161ã
170âã®æ·¡é»è²çµæ¶ã®ïŒâã€ãœãããã«âïŒâã¡
ãã«âïŒâããããã·ããªããžã³14.9ïœãåŸãã
åçã¯93.0ïŒ ã§ãã¬ã¹ã¯ãããã°ã©ãã€ãŒã«ãã
çŽåºŠã¯94.3ïŒ ã§ãã€ãã å®æœäŸ 13 æ¹æäžã®å®¹éïŒã®ãžã€ã±ããä»æš¹è槜ãäžå
容åšãšããŠå®éšå®€çšé£ç¶äžåè£ çœ®ãæ§æãããã
ã®å®¹åšäžã«FMIèšéãã³ãã«ãã€ãŠãšãã«ã€ãœ
ããã«ã€ãããŒãå¡©é žå¡©ããã«ãšã³ããã³æ°Žãé
å ¥ããããªã¡ãã«ã¢ãã³ïŒTMAïŒãããŒã¿ã¡ãŒ
ã¿ãŒãéããŠã¬ã¹ãšããŠåæ£ãããã容åšããã®
ãªãŒããŒãããŒã¯ãã«ã³ã¿ãŒãžãã³ãã§ç§»éãã
ãã®å Žã§çžãåé¢ããã ææ©çžãTMAâHClæœåºã®ããããã«ã³ã¿ãŒ
ããïŒïŒ4â³ããã»ã©ã€ã³ãµãã«ãºïŒProcelain
SaddlesïŒãã€ãæ°Žã§æºããã24â³ÃïŒïŒ4â³ã®ã«ã©
ã ãžéã€ããäžå容åšäžã«æåã«æå ¥ããéã¯ã
æ°Ž240mlããã³ãã«ãšã³132mlãšããããã10â以
äžã«å·åŽããããã®å®¹åšã«ïŒæéåœãããã«ãšã³
202ïœäžã®æº¶æ¶²ãšããŠãšãã«ã€ãœããã«ã€ãããŒ
ãHClïŒåæå€ïŒã€ãããŒã55.3ééïŒ ãHCl42.4
ééïŒ ïŒ208ïœãTMAïŒHClã«å¯ŸããŠ50ïŒ éå°
éïŒ214ïœãæ°Ž150ïœããã³ãã«ãšã³230ïœãäŸçµŠ
ããããã«ãšã³ããã³ãšãã«ã€ãœããã«ã€ãããŒ
ãHClïŒãã«ãšã³æº¶æ¶²äŸçµŠã©ã€ã³ïŒé 管ïŒã¯æ··å
çšïŒŽå管ã«ãã€ãŠä»ã®æåã®å ±éäŸçµŠã©ã€ã³ãšçµ
åããã枩床ã¯10ã20âã«ä¿ã€ãã容åšäžã®å®¹ç©
ã¯çŽ750mlã«å®ããããªãŒããŒãããŒã¯ãã«ã³ã¿
ãŒãžç§»ããïŒãªãŒããŒãããŒã©ã€ã³ã¯åäžãªææ©
溶åªâæ°Žæ··åç©ã確å®ã«åŸãããæš¹è槜ã®ã»ãŒäž
ã»ã©ã«ã€ãªãå¿ èŠããããïŒãæ°Žçžã¯ããªã¡ãã«ã¢
ãã³å埪ç°ã«ãã©ããïŒææ©çžã¯æŽæµã«ã©ã ã«é
ã€ããæŽæµæ°ŽïŒçŽ100ïœïŒã¯ïŒæéæ¯ã«äº€æããã
ãã®æŽæµã«ã©ã ã¯ãæŽæµæ°Žãäžå容åšã«å埪ç°ã
ããŠé£ç¶æäœã§ãããææ©çžããããæ³ã§ã®äžå
ã®éèšèŒããã®ãšåæ§ã«ããŠä¹Ÿç¥ããããšãã«ã€
ãœããã«ã€ãããŒãã®åçã¯95ã98ïŒ ã§ãã€ãã å®æœäŸ 14 容é250mlã®äžãå£äžžåºãã©ã¹ã³ã«ãã°ããã€
ãã¯ã¹ã¿ãŒã©ãŒã枩床èšããã³ä¹Ÿç¥ç®¡ãèšçœ®ã
ãããã©ã¹ã³äžã«ãžã±ãã³8.82ïœïŒ0.105ã¢ã«ïŒ
ããã³ãããªãŠã äžã®19.75ééïŒ ãšãã«ã€ãœã
ãã«ã€ãããŒã溶液58.22ïœïŒ0.1ã¢ã«ïŒãæå ¥ã
ãããã®æ··åç©ãæ¹æãã觊åªãšããŠæ°·é ¢é ž0.6
ïœïŒ0.01ã¢ã«ïŒãå ããã15ååŸã«åå¿ç©ã®æž©åºŠ
ã¯49âã«éãããã®æå€éšããã®å·åŽãéå§ã
ããæ··åç©ãããã«ïŒæéæ¹æããã¢ã³ã¢ãã¢ã¬
ã¹ãå°å ¥ãããã¢ã³ã¢ãã¢å°å ¥ã®ïŒæéåŸåå¿æ··
åç©ãïŒæéå ç±ãã溶åªãæžå§äžã§é€å»ããïŒ
âã€ãœãããã«âïŒâã¡ãã«âïŒâããããã·ã
ãªããžã³ã®åç70.1ïŒ ã§åºåœ¢ç©ïŒïŒâã€ãœããã
ã«âïŒâã¡ãã«âïŒâããããã·ããªããžã³ã
67.0ééïŒ å«æïŒ15.81ïœãåŸãã å®æœäŸ 15 容éïŒã®äºãå£äžžåºãã©ã¹ã³ã«æ©æ¢°æ¹æè£
眮ã枩床èšããã³ä¹Ÿç¥ç®¡ãèšçœ®ããããã©ã¹ã³äž
ã«ãã«ãšã³äžã®ä¹Ÿç¥ãšãã«ã€ãœããã«ã€ãããŒã
881.64ïœïŒ1.5ã¢ã«ïŒããã³ãžã±ãã³132.5ïœ
ïŒ1.58ã¢ã«ïŒãæå ¥ãããæ··åç©ãïŒâã«å·åŽãã
ãã«ãšã³äžã®TMA溶液21.42ïœïŒ0.08ã¢ã«ïŒãæ
å ¥ãããåå¿æ··åç©ã®æž©åºŠãïŒæéã«ããã€ãŠ30
â以äžã«èª¿ç¯ãããé±æ²¹åŽåºè£ 眮ããã³ã¬ã¹åæ£
管ãèšçœ®ã也ç¥ç®¡ã¯åãå€ãããã¢ã³ã¢ãã¢ã¬ã¹
ãïŒæéã«ããã€ãŠåå¿æ··åç©äžã«å¹ã蟌ã¿ãã
ã®éåå¿æž©åºŠã30â以äžã«èª¿ç¯ããããã®æç¹ã§
ãã€ãŒã³âã¹ã¿ãŒã¯ãã©ããããã³å·åŽç®¡ãèšçœ®
ããã¢ã³ã¢ãã¢ã®å°å ¥ãåæ¢ãããåå¿æ··åç©ã
å ç±ããéæµããŠæ°Žããã³ãšã¿ããŒã«ãå ±æ²žèžç
ã§é€ããªããèžæ°æž©åºŠã108âã«éãããŸã§éæµ
ãç¶ãããåå¿æ··åç©ã宀枩ã«å·åŽããæ¿å¡©é ž
156ïœããã³æ°Ž200mlãæ·»å ãåŸãããæ··åç©ãæ¿
ããæ¹æãããçžãåé¢ããæ°Žçžã枩床èšãæ©æ¢°
æ¹æè£ çœ®ãå€éšå ç±è£ 眮ãåãã容éïŒã®äžã
å£ã®åºéšã«æåºå£ãæããåå¿å®¹åšã«ç§»ããã次
ãã§æ°Žçžãæ®çºæ§ææ©æåãå ±æ²žèžçã§é€ããªã
ãïŒæééæµãããæ··åç©ã宀枩ãŸã§å·åŽããã
ã®æº¶æ¶²ã«ïŒïŒïŒâãžã¯ãããšã¿ã³ïŒEDCïŒ1.600
mlããã³50ïŒ æ°Žé žåãããªãŠã 氎溶液126ïœã
倫ã å ãããæ··åç©ã60âã«å ç±ããçžãåé¢ã
ããæ°Žçžã60âã§EDC200mlã§åæœåºããææ©æœ
åºçžãäžç·ã«ããããã®ææ©çžããç空äžã§æº¶åª
ãé€å»ããè€è²åºåœ¢ç©209.8ïœãåŸãããã®åºåœ¢
ç©ã¯åæã«ããã°ãïŒâã€ãœãããã«âïŒâã¡ã
ã«âïŒâããããã·ããªããžã³ã99.2ééïŒ å«æ
ãããšãã«ã€ãœããã«ã€ãããŒãã«å¯Ÿããåçã¯
91.9ïŒ ã§ãã€ããæ°Žçžäžã«ãç®çç©ãåç0.72ïŒ
ã§ååšããŠããã
Claims (1)
- ãç¹èš±è«æ±ã®ç¯å²ã ïŒ ïœïŒ 次åŒïŒ ïŒåŒäžã ã¯ççŽ ååæ°ïŒãªããïŒã®ã¢ã«ãã«åºãè¡š
ããã Râ²ã¯ççŽ ååæ°ïŒãªããïŒã®ã¢ã«ãã«åºã
è¡šãããïŒ ã§è¡šããããã€ãããŒãå¡©é žå¡©ãšéå°ã®å¡©åæ°Ž
çŽ ãšã®æ··åç©ãæ°Žäžæ··åæ§æº¶åªã®ååšäžã§æ°Žæ§
溶液äžã®é žå容æ§åŒ·å¡©åºã«ããäžåããŠéé¢ã€
ãããŒãã圢æããã ïœïŒ æ°Žçžãé€å»ãããããŠæº¶åªïŒã€ãããŒã溶
液çžäžã«æ®åããå šãŠã®æ°Žãé€å»ãã ïœïŒ ããªã¡ãã«ã¢ãã³ãããªãšãã«ã¢ãã³ãã
ã³é ¢é žãããªã矀ããéžæããã觊åªã®ååšäž
ã§ãã€ãããŒãïŒã¢ã«åœãããžã±ãã³ïŒãªãã
1.05ã¢ã«ã®æº¶æ¶²ãæ·»å ãã次åŒïŒ ïŒåŒäžãããã³Râ²ã¯åèšã®æå³ãè¡šãããïŒ ã§è¡šãããããªããµãžãã³ã圢æããã ïœïŒ 該ãªããµãžãã³æº¶æ¶²ã«ã¢ã³ã¢ãã¢ã¬ã¹ãå
ããŠïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâãããã
ã·ããªããžã³ã圢æããã ïœ ïŒ å·¥çšïœïŒã§çããæ°Žãå šãŠé€å»ãã ïœïŒ 䜿çšãã溶åªãé€å»ããããšã«ãããªã次
åŒïŒ ïŒåŒäžãã¯åèšã®æå³ãè¡šãããïŒ ã§è¡šããããïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâ
ããããã·ããªããžã³ã®è£œé æ¹æ³ã ïŒ ïŒ²ããããã«åºã§ãããRâ²ãã¡ãã«åºããš
ãã«åºããã³ãããã«åºããéžã°ããåºã§ããç¹
èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒ é žå容æ§åŒ·å¡©åºãã¢ã«ã«ãªéå±æ°Žé žåç©ãã
ã³ã¢ã«ã«ãªéå±çé žå¡©ããéžã°ããç¡æ©å¡©åºã§ã
ãç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒ é žå容æ§åŒ·å¡©åºãé žå容æ§ææ©å¡©åºã§ããç¹
èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒ é žå容æ§ææ©å¡©åºãã¢ã«ãã«åºã®ççŽ ååæ°
ïŒãªããïŒã®ããªã¢ã«ãã«ã¢ãã³ããã³ããªãžã³
ããããéžã°ããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹
æ³ã ïŒ é žå容æ§ææ©å¡©åºãããªã¡ãã«ã¢ãã³ã§ãã
ç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒ æ°Žäžæ··åæ§æº¶åªã液ç¶ã®æ°Žäžæ··åæ§è³éŠæã
ãã³èèªæçåæ°ŽçŽ ããã³å¡©çŽ çåæ°ŽçŽ ããéžã°
ããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒ æ°Žäžæ··åæ§æº¶åªããã³ãŒã³ããã«ãšã³ããã·
ã¬ã³ãããã¿ã³ãïŒïŒïŒïŒïŒâããªã¯ãããšã¿
ã³ãïŒïŒïŒïŒïŒâããªã¯ãããšã¿ã³ãããã©ã¯ã
ããšãã¬ã³ããéžã°ããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èš
èŒã®æ¹æ³ã ïŒ æ°Žäžæ··åæ§æº¶åªããã«ãšã³ã§ããç¹èš±è«æ±ã®
ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒïŒ åèšïœïŒå·¥çšã«ãããæ°Žçžé€å»åŸã®æº¶åªïŒ
ã€ãããŒã溶液çžäžã«æ®åããå šãŠã®æ°Žãå ±æ²žèž
çã§é€å»ããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒïŒ åèšïœïŒå·¥çšã«ãããæ°Žçžé€å»åŸã®æº¶åªïŒ
ã€ãããŒã溶液çžäžã«æ®åããå šãŠã®æ°Žã®é€å»
ããã¢ã¬ããŠã©ãŒã·ãŒãããã³ä¹Ÿç¥çšç¡æ°Žå¡©ãã
éžã°ããåºäœä¹Ÿç¥å€ã«æº¶åªïŒã€ãããŒã溶液çžã
æ¥è§Šãããããšã«ããè¡ãªãç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒ
é èšèŒã®æ¹æ³ã ïŒïŒ ãžã±ãã³ã«å¯Ÿããæ··åæ§æº¶åªããã«ãšã³ã
ããã©ã¯ãããšãã¬ã³ããã³ããªã¯ãããšãã¬ã³
ããéžã°ããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒïŒ 觊åªãããªã¡ãã«ã¢ãã³ããã³ããªãšãã«
ã¢ãã³ããéžã°ããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®
æ¹æ³ã ïŒïŒ 觊åªãããªã¡ãã«ã¢ãã³ã§ããç¹èš±è«æ±ã®
ç¯å²ç¬¬ïŒïŒé èšèŒã®æ¹æ³ã ïŒïŒ éé¢ã€ãããŒãããžã±ãã³ããã³è§Šåªãã
ã«ãšã³ã«æº¶è§£ããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹
æ³ã ïŒïŒ æ°ŽãïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâãã
ããã·ããªããžã³ããå ±æ²žèžçã«ãã€ãŠé€ãç¹èš±
è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒïŒ ãšãã«ã€ãœããã«ã€ãããŒãå¡©é žå¡©ããã«
ãšã³äžã«æº¶è§£ããããªã¡ãã«ã¢ãã³ã§äžåããé
é¢ã®ãšãã«ã€ãœããã«ã€ãããŒãããå ±æ²žèžçã«
ãã€ãŠæ°Žãé€å»ãããã«ãšã³äžã®ä¹Ÿç¥ãšãã«ã€ãœ
ããã«ã€ãããŒãããã«ãšã³ã«æº¶è§£ããéå°ã®ãž
ã±ãã³ãšããªã¡ãã«ã¢ãã³ã®ååšäžã§åå¿ããã
åŸãããææ©æº¶æ¶²ãçã¢ã«éã®æ°äœã¢ã³ã¢ãã¢ã§
åŠçããç¶ããŠå ±æ²žèžçããŠæ°Žãé€å»ããŠïŒâã€
ãœãããã«âïŒâã¡ãã«âïŒâããããã·ããªã
ãžã³ã圢æãããããã也ç¥ããŠææ©æº¶åªããå
åããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®æ¹æ³ã ïŒïŒ ïŒâã¢ã«ãã«âïŒâã¡ãã«âïŒâãããã
ã·ããªããžã³ãæ°Žæ§é žæº¶æ¶²ã§æœåºããå ç±ããŠå ±
沞èžçããäžåããæ¿ŸéããŠåé¢ããããŸãã¯æ
æ©æº¶åªäžãžæœåºããç¹èš±è«æ±ã®ç¯å²ç¬¬ïŒé èšèŒã®
æ¹æ³ã
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/932,087 US4163848A (en) | 1978-08-08 | 1978-08-08 | Process for the production of 2-alkyl- or cycloalkyl-4-methyl-6-hydroxypyrimidines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5524197A JPS5524197A (en) | 1980-02-21 |
| JPH048422B2 true JPH048422B2 (ja) | 1992-02-17 |
Family
ID=25461750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10115379A Granted JPS5524197A (en) | 1978-08-08 | 1979-08-08 | Manufacture of 22alkyllor cycloalkyll44 methyll66hydroxypyrimidine |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4163848A (ja) |
| JP (1) | JPS5524197A (ja) |
| CH (1) | CH640840A5 (ja) |
| DE (1) | DE2931887A1 (ja) |
| FR (1) | FR2426048B1 (ja) |
| GB (1) | GB2027710B (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3247926A1 (de) * | 1982-12-24 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 2-alkylthiomethyl-4-hydroxypyrimidinen |
| DE3344429A1 (de) * | 1983-12-08 | 1985-06-20 | Wacker-Chemie GmbH, 8000 MÃŒnchen | Verfahren zur herstellung von 2-isopropyl-4-methyl-6-hydroxypyrimidin |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1045237A (fr) * | 1950-11-29 | 1953-11-24 | British Ind Solvents Ltd | Perfectionnements à la préparation de pyrimidones substituces |
| GB699812A (en) * | 1950-11-29 | 1953-11-18 | British Ind Solvents Ltd | Manufacture of substituted pyrimidones |
| ZA15258B (ja) * | 1951-04-20 | 1900-01-01 | ||
| AU467752B2 (en) * | 1971-08-30 | 1975-12-11 | Westinghouse Electric Corporation | Electrical apparatus with ground fault detector with variable trip device |
| CH617452A5 (ja) * | 1974-10-25 | 1980-05-30 | Hoffmann La Roche | |
| US4012506A (en) * | 1975-07-03 | 1977-03-15 | Ciba-Geigy Corporation | Pyrimidyl thio- and dithio-phosphoric acid esters |
| US4014879A (en) * | 1975-07-03 | 1977-03-29 | Ciba-Geigy Corporation | Continuous process for the production of 2-alkyl or cycloalkyl-4-methyl-6-hydroxy-pyrimidines |
| US4018771A (en) * | 1976-08-23 | 1977-04-19 | Ciba-Geigy Corporation | Process for the production of 2-alkyl or 2-cycloalkyl-4-methyl-6-hydroxypyrimidines |
| US4052397A (en) * | 1976-11-22 | 1977-10-04 | Ciba-Geigy Corporation | Process for the production of 2-alkyl or 2-cycloalkyl-4-methyl-6-hydroxypyrimidines |
| US4052396A (en) * | 1976-11-22 | 1977-10-04 | Ciba-Geigy Corporation | Process for the production of 2-alkyl or 2-cycloalkyl-4-methyl-6-hydroxypyrimidines |
-
1978
- 1978-08-08 US US05/932,087 patent/US4163848A/en not_active Expired - Lifetime
-
1979
- 1979-08-03 CH CH715079A patent/CH640840A5/de not_active IP Right Cessation
- 1979-08-06 DE DE19792931887 patent/DE2931887A1/de active Granted
- 1979-08-07 FR FR7920163A patent/FR2426048B1/fr not_active Expired
- 1979-08-07 GB GB7927563A patent/GB2027710B/en not_active Expired
- 1979-08-08 JP JP10115379A patent/JPS5524197A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2426048A1 (ja) | 1979-12-14 |
| GB2027710A (en) | 1980-02-27 |
| FR2426048B1 (ja) | 1983-01-28 |
| CH640840A5 (de) | 1984-01-31 |
| US4163848A (en) | 1979-08-07 |
| DE2931887C2 (ja) | 1989-06-29 |
| GB2027710B (en) | 1982-12-08 |
| JPS5524197A (en) | 1980-02-21 |
| DE2931887A1 (de) | 1980-02-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2855466B1 (en) | Processes to produce certain 2-(pyridine-3-yl)thiazoles | |
| JPS6383079A (ja) | ïŒâã¯ãã«âïŒâã¯ãã«ã¡ãã«ãã¢ãŸãŒã«ã®è£œé æ³ | |
| TWI551592B (zh) | ä»¥å ©æ¥é©äŸè£œåïŒïŒïŒïŒäºåŽæ°§å·±é žé ¯ | |
| US4647689A (en) | Preparation of alkyl trifluoroacetoacetate | |
| JPH048422B2 (ja) | ||
| US6423866B1 (en) | Production of aminohalogencrotonates | |
| JP2743461B2 (ja) | ïŒâã¡ãã«âïŒâã¢ã«ãã«âïŒâãã©ãŸãŒã«ã«ã«ãã³é žãšã¹ãã«é¡ã®è£œé æ³ | |
| JP2672874B2 (ja) | ã·ãã·ã³ã®è£œæ³ | |
| JPH0662577B2 (ja) | ïŒâã¡ãã«âïŒâããããã·ãã©ãŸâã«ã®è£œé æ³ | |
| JPS6121229B2 (ja) | ||
| JPH11322643A (ja) | ã¯ããã¢ã«ãã³é¡ããã³ã¢ã«ããã«ã¢ãã³é¡ã®è£œé æ¹æ³ | |
| KR900001179B1 (ko) | 4-ìë¯žë ž-5-ëììœìë©ížíŒëŠ¬ë¯žë ì ë첎ì ì ì¡°ë°©ë² | |
| JP4030289B2 (ja) | βâã±ããããªã«é¡ã®è£œæ³ | |
| JP3944876B2 (ja) | ã¯ãšã³é žãšã¹ãã«é¡ã®è£œé æ¹æ³ | |
| JP2984848B2 (ja) | âã¢ã«ãã«ãã©ãŸãŒã«èªå°äœã®è£œæ³ | |
| JP2000159716A (ja) | ãªã«ããšã¹ãã«ã®è£œé æ¹æ³ | |
| JPS5962559A (ja) | çŽç²ãªãžã¢ã»ããããªã«ã®è£œæ³ | |
| JP3155909B2 (ja) | ïŒïŒïŒâãžã¢ã«ãã«âïŒâã€ãããŸãªãžãã³é¡ã®è£œé æ¹æ³ | |
| FR2537137A1 (fr) | Procede de preparation de derives de l'acide 2-thiophene acetique et produits intermediaires necessaires pour leur preparation | |
| JP3272340B2 (ja) | ïŒâïŒã·ã¯ããã³ãâïŒâãšã³âïŒâã€ã«ïŒã¡ãã«ïŒœâïŒâãšãã«âïŒâïŒïŒïŒïŒâãžã¡ãã«ãã³ãŸã€ã«ïŒâïŒïŒïŒâããªããžã³ãžãªã³ã®è£œé æ¹æ³ | |
| JPH0525876B2 (ja) | ||
| SU177895A1 (ru) | СÐÐСÐÐ ÐÐÐУЧÐÐÐЯ 2-(п-ÐÐÐÐÐÐÐÐÐÐÐСУÐЬЀÐÐÐÐÐ)- 4,6-ÐÐÐÐТÐÐÐÐÐ ÐÐÐÐÐÐÐ (СУÐЬЀÐÐÐÐÐÐÐÐÐ) | |
| JPS6117822B2 (ja) | ||
| JP2001516364A (ja) | ïŒïŒïŒâãžã¯ããâïŒâãã«ãªããã³ãããããªã«ã®è£œé æ¹æ³ãåã³ååç©ïŒâã·ã¢ãâïŒâããããã·âïŒâãã«ãªãããªãâïŒâãªã³âãããªãŠã å¡©ãšãã®äºå€ç°æ§äœ | |
| US6388151B1 (en) | Synthesis of Tetraalkylcyclopentadienes |