JPH0412268B2 - - Google Patents

Info

Publication number
JPH0412268B2
JPH0412268B2 JP58028135A JP2813583A JPH0412268B2 JP H0412268 B2 JPH0412268 B2 JP H0412268B2 JP 58028135 A JP58028135 A JP 58028135A JP 2813583 A JP2813583 A JP 2813583A JP H0412268 B2 JPH0412268 B2 JP H0412268B2
Authority
JP
Japan
Prior art keywords
compound
bacteria
antibacterial
norfloxacin
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58028135A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59155381A (ja
Inventor
Tsutomu Irikura
Satoru Murayama
Tochio Iinuma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Priority to JP58028135A priority Critical patent/JPS59155381A/ja
Priority to AU24578/84A priority patent/AU2457884A/en
Priority to GB848404223A priority patent/GB8404223D0/en
Priority to SE8400853A priority patent/SE459809B/sv
Priority to FR8402530A priority patent/FR2541278B1/fr
Priority to US06/581,957 priority patent/US4599418A/en
Priority to CA000447876A priority patent/CA1225091A/en
Priority to DE3406235A priority patent/DE3406235C2/de
Priority to AU24832/84A priority patent/AU559156B2/en
Priority to IT19740/84A priority patent/IT1173336B/it
Priority to GB08404691A priority patent/GB2138806B/en
Priority to KR1019840000865A priority patent/KR900001547B1/ko
Priority to ES529962A priority patent/ES8600274A1/es
Publication of JPS59155381A publication Critical patent/JPS59155381A/ja
Publication of JPH0412268B2 publication Critical patent/JPH0412268B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP58028135A 1983-02-22 1983-02-22 ベンゾキノリジンカルボン酸誘導体及びその製造法 Granted JPS59155381A (ja)

Priority Applications (13)

Application Number Priority Date Filing Date Title
JP58028135A JPS59155381A (ja) 1983-02-22 1983-02-22 ベンゾキノリジンカルボン酸誘導体及びその製造法
AU24578/84A AU2457884A (en) 1983-02-22 1984-02-14 Benzoquinolizine carboxylic acid derivatives
GB848404223A GB8404223D0 (en) 1983-02-22 1984-02-17 Heterocyclic carboxylic acid antibacterial compounds
SE8400853A SE459809B (sv) 1983-02-22 1984-02-17 Bensokinolizin-karboxylsyraderivat och foerfarande foer framstaellning daerav
FR8402530A FR2541278B1 (fr) 1983-02-22 1984-02-20 Procede de preparation de derives d'acide benzoquinolizinecarboxylique, nouveaux produits ainsi obtenus et leur utilisation comme agents antibacteriens
US06/581,957 US4599418A (en) 1983-02-22 1984-02-21 Benzoquinolizine carboxylic acid derivatives, and process for preparation thereof
CA000447876A CA1225091A (en) 1983-02-22 1984-02-21 Benzoquinolizine carboxylic acid derivatives, and process for preparation thereof
DE3406235A DE3406235C2 (de) 1983-02-22 1984-02-21 Benzochinolizincarbonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung
AU24832/84A AU559156B2 (en) 1983-02-22 1984-02-22 Benzo(ij)-quinolizine derivatives
IT19740/84A IT1173336B (it) 1983-02-22 1984-02-22 Derivati dell'acido benzochinolizin carbossilico,e processo per la preparazione di essi
GB08404691A GB2138806B (en) 1983-02-22 1984-02-22 Benzoquinolizine carboxylic acid anti-bacterial compounds
KR1019840000865A KR900001547B1 (ko) 1983-02-22 1984-02-22 벤조퀴놀리진 카르복실산 유도체의 제조방법
ES529962A ES8600274A1 (es) 1983-02-22 1984-02-22 Procedimiento para preparar un derivado de acido benzoquinolizina carboxilico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58028135A JPS59155381A (ja) 1983-02-22 1983-02-22 ベンゾキノリジンカルボン酸誘導体及びその製造法

Publications (2)

Publication Number Publication Date
JPS59155381A JPS59155381A (ja) 1984-09-04
JPH0412268B2 true JPH0412268B2 (en, 2012) 1992-03-04

Family

ID=12240322

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58028135A Granted JPS59155381A (ja) 1983-02-22 1983-02-22 ベンゾキノリジンカルボン酸誘導体及びその製造法

Country Status (11)

Country Link
US (1) US4599418A (en, 2012)
JP (1) JPS59155381A (en, 2012)
KR (1) KR900001547B1 (en, 2012)
AU (2) AU2457884A (en, 2012)
CA (1) CA1225091A (en, 2012)
DE (1) DE3406235C2 (en, 2012)
ES (1) ES8600274A1 (en, 2012)
FR (1) FR2541278B1 (en, 2012)
GB (2) GB8404223D0 (en, 2012)
IT (1) IT1173336B (en, 2012)
SE (1) SE459809B (en, 2012)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472405A (en) * 1982-11-12 1984-09-18 Riker Laboratories, Inc. Antimicrobial 6,7-dihydro-5,8-dimethyl-9 fluoro-1-oxo-1H, 5H-benzo (ij) quinolizine-2-carboxylic acid and derivatives
JPH08775B2 (ja) * 1986-05-22 1996-01-10 協和醗酵工業株式会社 魚類のパスツレラ属細菌性類結節症治療剤
US6750224B1 (en) 1999-05-07 2004-06-15 Wockhardt Limited Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
US7247642B2 (en) 1999-05-07 2007-07-24 Wockhardt Limited Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
US6514986B2 (en) 2000-11-22 2003-02-04 Wockhardt Limited Chiral fluoroquinolone arginine salt forms
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
CN1649600A (zh) * 2002-02-28 2005-08-03 A&D生物科学公司 氟西汀及类似物的糖醛酰胺、苷和原酸酯苷及其应用
WO2003079980A2 (en) * 2002-03-19 2003-10-02 A & D Bioscience, Inc. Caboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins, analogs, and uses thereof
US20050255038A1 (en) * 2002-04-12 2005-11-17 A And D Bioscience, Inc. Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents and uses thereof
WO2003094842A2 (en) * 2002-05-07 2003-11-20 A & D Bioscience, Inc. Conjugates comprising central nervous system active drug
US6664267B1 (en) 2002-05-28 2003-12-16 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
US20050215487A1 (en) * 2002-06-27 2005-09-29 Holick Michael F Conjugates comprising an nsaid and a sugar and uses thereof
AU2003304460A1 (en) 2003-09-04 2005-03-29 Wockhardt Limited Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
HK1252318A1 (zh) * 2015-07-28 2019-05-24 Vyome Therapeutics Limited 抗菌治療劑和預防劑

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019910B2 (ja) * 1979-10-11 1985-05-18 大塚製薬株式会社 ベンゾ〔ｉｊ〕キノリジン−２−カルボン酸誘導体及びその製造法
US4416884A (en) * 1978-04-12 1983-11-22 Otsuka Pharmaceutical Co., Ltd. Piperazinylbenzoheterocyclic compounds
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
NO156828C (no) * 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
AT380250B (de) * 1980-12-18 1986-04-25 Otsuka Pharma Co Ltd Verfahren zur herstellung benzoheterocyclischer verbindungen
JPS57145862A (en) * 1981-03-06 1982-09-09 Kyorin Pharmaceut Co Ltd Quinolinecarboxylic acid derivative

Also Published As

Publication number Publication date
GB8404691D0 (en) 1984-03-28
SE8400853D0 (sv) 1984-02-17
DE3406235A1 (de) 1984-10-11
GB2138806B (en) 1986-05-21
GB8404223D0 (en) 1984-03-21
US4599418A (en) 1986-07-08
AU2457884A (en) 1984-08-30
AU2483284A (en) 1984-08-30
KR840007878A (ko) 1984-12-11
CA1225091A (en) 1987-08-04
IT1173336B (it) 1987-06-24
GB2138806A (en) 1984-10-31
FR2541278B1 (fr) 1986-09-26
FR2541278A1 (fr) 1984-08-24
DE3406235C2 (de) 1994-12-22
AU559156B2 (en) 1987-02-26
SE8400853L (sv) 1984-08-23
SE459809B (sv) 1989-08-07
JPS59155381A (ja) 1984-09-04
KR900001547B1 (ko) 1990-03-12
IT8419740A0 (it) 1984-02-22
ES529962A0 (es) 1985-10-01
ES8600274A1 (es) 1985-10-01

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