KR840007878A - 벤조퀴놀리진 카르복실산 유도체의 제조방법 - Google Patents

벤조퀴놀리진 카르복실산 유도체의 제조방법 Download PDF

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Publication number
KR840007878A
KR840007878A KR1019840000865A KR840000865A KR840007878A KR 840007878 A KR840007878 A KR 840007878A KR 1019840000865 A KR1019840000865 A KR 1019840000865A KR 840000865 A KR840000865 A KR 840000865A KR 840007878 A KR840007878 A KR 840007878A
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KR
South Korea
Prior art keywords
carboxylic acid
preparing
acid derivative
benzoquinolizine carboxylic
benzoquinolizine
Prior art date
Application number
KR1019840000865A
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English (en)
Other versions
KR900001547B1 (ko
Inventor
쓰토무(외 2) 이리구라
Original Assignee
하기하라 히데시
쿄오린 세이야꾸 가부시기가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of KR840007878A publication Critical patent/KR840007878A/ko
Application granted granted Critical
Publication of KR900001547B1 publication Critical patent/KR900001547B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

내용 없음.

Description

벤조퀴놀리진 카르복실산 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 8-[4-(4-니트로벤질)-1-피페라지닐]-9-플루오로-6,7-디하이드로-5-메틸-1-옥소-1H, 5H-벤조[ij] 퀴놀리진-2-카르복실산 이나 그 산첨가염을 환원시키는 것으로 구성되는 8-[4-(4-아미노벤질)-1-피페라지닐]-9-플루오로-6,7-디하이드로-5-메틸-1-옥소-1H, 5H-벤조[ij] 퀴놀리진-2-카르복실산, 그 수화물 및 산첨가염의 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840000865A 1983-02-22 1984-02-22 벤조퀴놀리진 카르복실산 유도체의 제조방법 KR900001547B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58028135A JPS59155381A (ja) 1983-02-22 1983-02-22 ベンゾキノリジンカルボン酸誘導体及びその製造法
JP28135 1983-02-22

Publications (2)

Publication Number Publication Date
KR840007878A true KR840007878A (ko) 1984-12-11
KR900001547B1 KR900001547B1 (ko) 1990-03-12

Family

ID=12240322

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840000865A KR900001547B1 (ko) 1983-02-22 1984-02-22 벤조퀴놀리진 카르복실산 유도체의 제조방법

Country Status (11)

Country Link
US (1) US4599418A (ko)
JP (1) JPS59155381A (ko)
KR (1) KR900001547B1 (ko)
AU (2) AU2457884A (ko)
CA (1) CA1225091A (ko)
DE (1) DE3406235C2 (ko)
ES (1) ES529962A0 (ko)
FR (1) FR2541278B1 (ko)
GB (2) GB8404223D0 (ko)
IT (1) IT1173336B (ko)
SE (1) SE459809B (ko)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472405A (en) * 1982-11-12 1984-09-18 Riker Laboratories, Inc. Antimicrobial 6,7-dihydro-5,8-dimethyl-9 fluoro-1-oxo-1H, 5H-benzo (ij) quinolizine-2-carboxylic acid and derivatives
JPH08775B2 (ja) * 1986-05-22 1996-01-10 協和醗酵工業株式会社 魚類のパスツレラ属細菌性類結節症治療剤
EP2030620A1 (en) * 1999-05-07 2009-03-04 Wockhardt Limited (s)-benzoquinolizine carboxylic acids and their use as antibacterial agents
US6750224B1 (en) 1999-05-07 2004-06-15 Wockhardt Limited Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
US6514986B2 (en) 2000-11-22 2003-02-04 Wockhardt Limited Chiral fluoroquinolone arginine salt forms
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) * 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
WO2003073988A2 (en) * 2002-02-28 2003-09-12 A & D Bioscience, Inc. Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof
US20050107310A1 (en) * 2002-03-19 2005-05-19 Holick Michael F. Carboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins, analogs, and uses thereof
WO2003086475A1 (en) * 2002-04-12 2003-10-23 A & D Bioscience, Inc. Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents, and uses thereof
US20050153928A1 (en) * 2002-05-07 2005-07-14 Holick Michael F. Conjugates comprising a central nervous system-active drug linked to glucuronic acid or glucosamine through an amide bond and uses thereof
WO2003099815A1 (en) * 2002-05-28 2003-12-04 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
US20050215487A1 (en) * 2002-06-27 2005-09-29 Holick Michael F Conjugates comprising an nsaid and a sugar and uses thereof
PL214849B1 (pl) 2003-09-04 2013-09-30 Wockhardt Ltd Tetrahydrat soli kwasu benzochinolizyno-2-karboksylowego z arginina, sposób jego wytwarzania, kompozycja zawierajaca przedmiotowy tetrahydrat soli oraz jego zastosowanie
MX2018001075A (es) * 2015-07-28 2019-04-15 Vyome Therapeutics Ltd Agentes terapeuticos y profilacticos antibacterianos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019910B2 (ja) * 1979-10-11 1985-05-18 大塚製薬株式会社 ベンゾ〔ｉｊ〕キノリジン−２−カルボン酸誘導体及びその製造法
US4416884A (en) * 1978-04-12 1983-11-22 Otsuka Pharmaceutical Co., Ltd. Piperazinylbenzoheterocyclic compounds
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
NO156828C (no) * 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
PT74145B (en) * 1980-12-18 1983-05-30 Otsuka Pharma Co Ltd Process for preparing benzoheterocyclic compounds
JPS57145862A (en) * 1981-03-06 1982-09-09 Kyorin Pharmaceut Co Ltd Quinolinecarboxylic acid derivative

Also Published As

Publication number Publication date
ES8600274A1 (es) 1985-10-01
SE459809B (sv) 1989-08-07
FR2541278B1 (fr) 1986-09-26
US4599418A (en) 1986-07-08
KR900001547B1 (ko) 1990-03-12
GB8404691D0 (en) 1984-03-28
AU2483284A (en) 1984-08-30
JPH0412268B2 (ko) 1992-03-04
SE8400853D0 (sv) 1984-02-17
GB2138806A (en) 1984-10-31
AU559156B2 (en) 1987-02-26
AU2457884A (en) 1984-08-30
IT8419740A0 (it) 1984-02-22
DE3406235A1 (de) 1984-10-11
DE3406235C2 (de) 1994-12-22
SE8400853L (sv) 1984-08-23
ES529962A0 (es) 1985-10-01
CA1225091A (en) 1987-08-04
GB2138806B (en) 1986-05-21
IT1173336B (it) 1987-06-24
FR2541278A1 (fr) 1984-08-24
JPS59155381A (ja) 1984-09-04
GB8404223D0 (en) 1984-03-21

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