JPH0231070B2 - - Google Patents

Info

Publication number
JPH0231070B2
JPH0231070B2 JP62282659A JP28265987A JPH0231070B2 JP H0231070 B2 JPH0231070 B2 JP H0231070B2 JP 62282659 A JP62282659 A JP 62282659A JP 28265987 A JP28265987 A JP 28265987A JP H0231070 B2 JPH0231070 B2 JP H0231070B2
Authority
JP
Japan
Prior art keywords
acid
rats
gastric
ulcer
test compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62282659A
Other languages
English (en)
Japanese (ja)
Other versions
JPS63165361A (ja
Inventor
Hiroshi Wada
Masatoshi Kawamori
Hajime Tamaki
Juichi Onoda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of JPS63165361A publication Critical patent/JPS63165361A/ja
Publication of JPH0231070B2 publication Critical patent/JPH0231070B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C301/00—Esters of sulfurous acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/57—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing carboxyl groups bound to the carbon skeleton
    • C07C309/58—Carboxylic acid groups or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP62282659A 1981-10-22 1987-11-09 新規スルホデヒドロアビエチン酸塩 Granted JPS63165361A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8131856 1981-10-22
GB08131856A GB2107584A (en) 1981-10-22 1981-10-22 Treatment of gastro-intestinal diseases
GB8218707 1982-06-29

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP57185883A Division JPS5877814A (ja) 1981-10-22 1982-10-21 抗潰瘍剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP1273358A Division JPH02167258A (ja) 1981-10-22 1989-10-19 新規スルホデヒドロアビエチン酸塩

Publications (2)

Publication Number Publication Date
JPS63165361A JPS63165361A (ja) 1988-07-08
JPH0231070B2 true JPH0231070B2 (enrdf_load_stackoverflow) 1990-07-11

Family

ID=10525330

Family Applications (2)

Application Number Title Priority Date Filing Date
JP57185883A Granted JPS5877814A (ja) 1981-10-22 1982-10-21 抗潰瘍剤
JP62282659A Granted JPS63165361A (ja) 1981-10-22 1987-11-09 新規スルホデヒドロアビエチン酸塩

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP57185883A Granted JPS5877814A (ja) 1981-10-22 1982-10-21 抗潰瘍剤

Country Status (2)

Country Link
JP (2) JPS5877814A (enrdf_load_stackoverflow)
GB (1) GB2107584A (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3059092B2 (ja) 1995-11-15 2000-07-04 田辺製薬株式会社 ドライアイおよびドライアイを原因とする疾患の予防・治療剤
TW585762B (en) * 1999-11-11 2004-05-01 Tanabe Seiyaku Co Pharmaceutical composition for prophylaxis or treatment of inflammatory bowel diseases
TWI227137B (en) * 2001-09-27 2005-02-01 Tanabe Seiyaku Co Aqueous solution of ecabet sodium
JPWO2007040005A1 (ja) * 2005-09-06 2009-04-16 国立大学法人京都大学 ペルオキシソーム増殖剤応答性受容体ＰＰＡＲα活性化剤、および該活性化剤を含有する特定症状の予防または改善用組成物
JP4839460B1 (ja) * 2011-04-28 2011-12-21 丸一株式会社 遠隔操作式排水栓装置のレリースワイヤ連結構造
CN103772241B (zh) * 2014-01-07 2015-08-26 珠海亿邦制药股份有限公司 一种磺化去氢松香酸盐的制备方法
CN111377836A (zh) * 2018-12-29 2020-07-07 四川科瑞德制药股份有限公司 一种依卡倍特钠晶型及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2121032A (en) * 1936-03-24 1938-06-21 G & A Lab Detergent and wetting agent and process of producing the same

Also Published As

Publication number Publication date
JPS63165361A (ja) 1988-07-08
GB2107584A (en) 1983-05-05
JPS6323174B2 (enrdf_load_stackoverflow) 1988-05-16
JPS5877814A (ja) 1983-05-11

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