JPH0160479B2 - - Google Patents

Info

Publication number
JPH0160479B2
JPH0160479B2 JP63261676A JP26167688A JPH0160479B2 JP H0160479 B2 JPH0160479 B2 JP H0160479B2 JP 63261676 A JP63261676 A JP 63261676A JP 26167688 A JP26167688 A JP 26167688A JP H0160479 B2 JPH0160479 B2 JP H0160479B2
Authority
JP
Japan
Prior art keywords
formula
hydroxy
pregnane
derivative
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP63261676A
Other languages
English (en)
Japanese (ja)
Other versions
JPH01131194A (ja
Inventor
Uinterusu Jorujo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit SpA filed Critical Lepetit SpA
Publication of JPH01131194A publication Critical patent/JPH01131194A/ja
Publication of JPH0160479B2 publication Critical patent/JPH0160479B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0011—Unsubstituted amino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP63261676A 1980-11-26 1988-10-19 プレグナノ［１７α，１６α−ｄ］オキサゾリン誘導体の製造法 Granted JPH01131194A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT26229/80A IT1134455B (it) 1980-11-26 1980-11-26 Procedimento per la preparazione di derivati 16alfa-idrossi-17alfa-aminopregnanici
IT26229A/80 1980-11-26

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP56187926A Division JPS57118600A (en) 1980-11-26 1981-11-25 Manufacture of 16alpha-hydroxy-17alpha- aminopregnane derivatives

Publications (2)

Publication Number Publication Date
JPH01131194A JPH01131194A (ja) 1989-05-24
JPH0160479B2 true JPH0160479B2 (OSRAM) 1989-12-22

Family

ID=11218998

Family Applications (3)

Application Number Title Priority Date Filing Date
JP56187926A Granted JPS57118600A (en) 1980-11-26 1981-11-25 Manufacture of 16alpha-hydroxy-17alpha- aminopregnane derivatives
JP63261676A Granted JPH01131194A (ja) 1980-11-26 1988-10-19 プレグナノ［１７α，１６α−ｄ］オキサゾリン誘導体の製造法
JP1006089A Pending JPH01238598A (ja) 1980-11-26 1989-01-17 １６α―ヒドロキシ―１７α―アミノプレグネン誘導体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP56187926A Granted JPS57118600A (en) 1980-11-26 1981-11-25 Manufacture of 16alpha-hydroxy-17alpha- aminopregnane derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1006089A Pending JPH01238598A (ja) 1980-11-26 1989-01-17 １６α―ヒドロキシ―１７α―アミノプレグネン誘導体

Country Status (16)

Country Link
US (1) US4412953A (OSRAM)
JP (3) JPS57118600A (OSRAM)
KR (1) KR870001903B1 (OSRAM)
AU (1) AU548998B2 (OSRAM)
BE (1) BE891242A (OSRAM)
CA (1) CA1176239A (OSRAM)
CH (1) CH657860A5 (OSRAM)
DE (1) DE3146785C2 (OSRAM)
FR (1) FR2494699A1 (OSRAM)
GB (1) GB2088382B (OSRAM)
HK (1) HK91086A (OSRAM)
IT (1) IT1134455B (OSRAM)
MY (1) MY8700182A (OSRAM)
NL (1) NL194645C (OSRAM)
NZ (1) NZ199056A (OSRAM)
SG (1) SG65486G (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2683530B1 (fr) * 1991-11-08 1994-01-21 Roussel Uclaf Nouveau procede de preparation de derives 20-oxo 17 alpha, 21-dihydroxyles du pregnane et nouveaux intermediaires.
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
CA2496867A1 (en) * 2002-08-28 2004-03-11 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatment methods
US20050101581A1 (en) * 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH444859A (de) * 1962-02-20 1967-10-15 Richter Gedeon Vegyeszet Verfahren zur Herstellung von neuen, im D-Ring basisch substituierten, 3-Keto-Steroiden
NL128816C (OSRAM) * 1965-04-22
IL31997A (en) * 1968-05-03 1974-03-14 Lepetit Spa Process for the preparation of pregnano(17alpha,16alpha-d)oxazolines and 16alpha,21-dihydroxy-17alpha-aminopregnanes
GB1478968A (en) * 1973-07-11 1977-07-06 Akzo Nv Alkylated pregnanes
US4031075A (en) * 1973-07-11 1977-06-21 Akzona Incorporated Alkylated pregnanes and process for obtaining same

Also Published As

Publication number Publication date
FR2494699B1 (OSRAM) 1983-12-09
JPH0124159B2 (OSRAM) 1989-05-10
FR2494699A1 (fr) 1982-05-28
JPH01238598A (ja) 1989-09-22
GB2088382B (en) 1984-12-12
CH657860A5 (it) 1986-09-30
US4412953A (en) 1983-11-01
KR830007714A (ko) 1983-11-04
IT8026229A0 (it) 1980-11-26
BE891242A (fr) 1982-05-25
NL194645B (nl) 2002-06-03
AU548998B2 (en) 1986-01-09
MY8700182A (en) 1987-12-31
KR870001903B1 (ko) 1987-10-21
GB2088382A (en) 1982-06-09
DE3146785C2 (de) 1997-06-12
NL8105201A (nl) 1982-06-16
SG65486G (en) 1987-03-27
JPH01131194A (ja) 1989-05-24
NL194645C (nl) 2002-10-04
NZ199056A (en) 1984-07-06
IT1134455B (it) 1986-08-13
HK91086A (en) 1986-12-05
JPS57118600A (en) 1982-07-23
DE3146785A1 (de) 1982-07-01
CA1176239A (en) 1984-10-16
AU7786381A (en) 1982-06-03

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