JPH0156777B2 - - Google Patents
Info
- Publication number
- JPH0156777B2 JPH0156777B2 JP55070060A JP7006080A JPH0156777B2 JP H0156777 B2 JPH0156777 B2 JP H0156777B2 JP 55070060 A JP55070060 A JP 55070060A JP 7006080 A JP7006080 A JP 7006080A JP H0156777 B2 JPH0156777 B2 JP H0156777B2
- Authority
- JP
- Japan
- Prior art keywords
- bone
- pores
- porous body
- porous
- filling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000000988 bone and bone Anatomy 0.000 claims description 74
- 239000011148 porous material Substances 0.000 claims description 63
- 230000007547 defect Effects 0.000 claims description 31
- 238000011049 filling Methods 0.000 claims description 28
- 239000000463 material Substances 0.000 claims description 22
- 239000001506 calcium phosphate Substances 0.000 claims description 13
- 239000000945 filler Substances 0.000 claims description 12
- 239000011575 calcium Substances 0.000 claims description 11
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 11
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 11
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 9
- -1 calcium phosphate compound Chemical class 0.000 claims description 9
- 235000011010 calcium phosphates Nutrition 0.000 claims description 9
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 7
- 239000002002 slurry Substances 0.000 claims description 6
- 229910019142 PO4 Inorganic materials 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- 235000019731 tricalcium phosphate Nutrition 0.000 claims description 4
- 229910000391 tricalcium phosphate Inorganic materials 0.000 claims description 4
- 229940078499 tricalcium phosphate Drugs 0.000 claims description 4
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 claims description 3
- 238000000034 method Methods 0.000 description 12
- 230000011164 ossification Effects 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 4
- 239000013078 crystal Substances 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 210000000689 upper leg Anatomy 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- 208000005422 Foreign-Body reaction Diseases 0.000 description 3
- 229910010293 ceramic material Inorganic materials 0.000 description 3
- 229920001436 collagen Polymers 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 238000010304 firing Methods 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 230000002188 osteogenic effect Effects 0.000 description 3
- 208000018084 Bone neoplasm Diseases 0.000 description 2
- 229920000049 Carbon (fiber) Polymers 0.000 description 2
- 230000000735 allogeneic effect Effects 0.000 description 2
- 239000004917 carbon fiber Substances 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 230000000399 orthopedic effect Effects 0.000 description 2
- 210000000963 osteoblast Anatomy 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 208000006386 Bone Resorption Diseases 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 208000024779 Comminuted Fractures Diseases 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000002805 bone matrix Anatomy 0.000 description 1
- 230000024279 bone resorption Effects 0.000 description 1
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 1
- XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 235000019700 dicalcium phosphate Nutrition 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 210000001621 ilium bone Anatomy 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000009834 vaporization Methods 0.000 description 1
- 230000008016 vaporization Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
- C04B35/447—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on phosphates, e.g. hydroxyapatite
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B38/00—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
- C04B38/06—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof by burning-out added substances by burning natural expanding materials or by sublimating or melting out added substances
- C04B38/0615—Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof by burning-out added substances by burning natural expanding materials or by sublimating or melting out added substances the burned-out substance being a monolitic element having approximately the same dimensions as the final article, e.g. a porous polyurethane sheet or a prepreg obtained by bonding together resin particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ceramic Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Structural Engineering (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Inorganic Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7006080A JPS56166843A (en) | 1980-05-28 | 1980-05-28 | Filler for bone broken section and void section |
| NLAANVRAGE8102354,A NL182774C (nl) | 1980-05-28 | 1981-05-13 | Werkwijze voor het bereiden van een vervangingsmiddel voor bot. |
| GB8115770A GB2078696B (en) | 1980-05-28 | 1981-05-22 | Filler for implanting in defects or hollow portions of bones |
| DE3121182A DE3121182C2 (de) | 1980-05-28 | 1981-05-27 | Füllmaterial zum Füllen von Defekten oder Hohlräumen in Knochen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7006080A JPS56166843A (en) | 1980-05-28 | 1980-05-28 | Filler for bone broken section and void section |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56166843A JPS56166843A (en) | 1981-12-22 |
| JPH0156777B2 true JPH0156777B2 (fr) | 1989-12-01 |
Family
ID=13420618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7006080A Granted JPS56166843A (en) | 1980-05-28 | 1980-05-28 | Filler for bone broken section and void section |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS56166843A (fr) |
| DE (1) | DE3121182C2 (fr) |
| GB (1) | GB2078696B (fr) |
| NL (1) | NL182774C (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109133907A (zh) * | 2018-08-16 | 2019-01-04 | 迈海新型材料科技（固安）有限公司 | 一种包含羟基磷灰石晶须和双相钙磷的人工骨及其制备方法 |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57119745A (en) * | 1981-01-17 | 1982-07-26 | Kyoto Ceramic | Bone prosthetic member |
| CA1247960A (fr) | 1983-03-24 | 1989-01-03 | Hideki Aoki | Implant transcutane |
| JPS6014860A (ja) * | 1983-07-06 | 1985-01-25 | 三菱鉱業セメント株式会社 | 無機質インプラント材 |
| DE3325111A1 (de) * | 1983-07-12 | 1985-01-24 | Merck Patent Gmbh, 6100 Darmstadt | Implantationsmaterialien |
| US4654314A (en) * | 1983-07-09 | 1987-03-31 | Sumitomo Cement Co., Ltd. | Porous ceramic material and processes for preparing same |
| JPS6021763A (ja) * | 1983-07-15 | 1985-02-04 | ティーディーケイ株式会社 | 人工骨材料 |
| ATE31616T1 (de) * | 1983-10-20 | 1988-01-15 | Oscobal Ag | Knochenersatzmaterial auf der basis natuerlicher knochen. |
| JPS6171059A (ja) * | 1984-09-13 | 1986-04-11 | 名神株式会社 | 骨、歯牙充填用組成物およびその製造方法 |
| JPS6171060A (ja) * | 1984-09-13 | 1986-04-11 | 名神株式会社 | 骨、歯牙充填用のα―リン酸三カルシウム含有組成物 |
| JPS6179462A (ja) * | 1984-09-25 | 1986-04-23 | ティーディーケイ株式会社 | 多孔質人工骨材料 |
| US4629464A (en) * | 1984-09-25 | 1986-12-16 | Tdk Corporation | Porous hydroxyapatite material for artificial bone substitute |
| JPS62501132A (ja) * | 1984-12-14 | 1987-05-07 | ドレナ−ト・クラウス | 骨代替材料 |
| JPS61170471A (ja) * | 1985-01-25 | 1986-08-01 | 住友大阪セメント株式会社 | 骨補綴成形体 |
| JPS62295666A (ja) * | 1986-06-16 | 1987-12-23 | 呉羽化学工業株式会社 | 連続二次元多孔型インプラント材及びその製造法 |
| JPS63125259A (ja) * | 1986-11-14 | 1988-05-28 | 旭光学工業株式会社 | リン酸カルシウム系多孔質骨補填材 |
| US4861733A (en) * | 1987-02-13 | 1989-08-29 | Interpore International | Calcium phosphate bone substitute materials |
| JPS63317158A (ja) * | 1987-06-22 | 1988-12-26 | Sangi:Kk | 骨接ぎ治癒促進材 |
| JPS6418949A (en) * | 1987-07-10 | 1989-01-23 | Asahi Optical Co Ltd | Production of powder agent for calcium phosphate based hardened body |
| JPS6456056A (en) * | 1987-08-26 | 1989-03-02 | Dental Chem Co Ltd | Hydroxyapatite bone filling material |
| JPH021285A (ja) * | 1988-01-11 | 1990-01-05 | Asahi Optical Co Ltd | 固着可能な歯科用及び医科用顆粒状骨補填材、その固着方法及び骨補填物 |
| DE3903695A1 (de) * | 1989-02-08 | 1990-08-09 | Merck Patent Gmbh | Resorbierbare knochenkeramik auf basis von tricalciumphosphat |
| JPH03116824U (fr) * | 1990-03-13 | 1991-12-03 | ||
| GB2354518B (en) * | 1996-10-04 | 2001-06-13 | Dytech Corp Ltd | A porous ceramic body composed of bonded particles |
| WO1998016267A1 (fr) * | 1996-10-15 | 1998-04-23 | University College Dublin | Matieres de substitution osseuse a systeme d'interconnexion des pores |
| DE19825419C2 (de) * | 1998-06-06 | 2002-09-19 | Gerber Thomas | Verfahren zur Herstellung eines hochporösen Knochenersatzmaterials sowie dessen Verwendung |
| GB9821663D0 (en) | 1998-10-05 | 1998-11-25 | Abonetics Ltd | Foamed ceramics |
| JP3400740B2 (ja) * | 1999-04-13 | 2003-04-28 | 東芝セラミックス株式会社 | リン酸カルシウム系多孔質焼結体およびその製造方法 |
| WO2001044141A2 (fr) * | 1999-12-16 | 2001-06-21 | Isotis N.V. | Corps en ceramique poreux |
| US20020022885A1 (en) * | 2000-05-19 | 2002-02-21 | Takahiro Ochi | Biomaterial |
| GB0013870D0 (en) * | 2000-06-07 | 2000-08-02 | Univ London | Foamed ceramics |
| US6713420B2 (en) | 2000-10-13 | 2004-03-30 | Toshiba Ceramics Co., Ltd. | Porous ceramics body for in vivo or in vitro use |
| JP4070951B2 (ja) | 2000-12-07 | 2008-04-02 | ペンタックス株式会社 | 多孔質リン酸カルシウム系セラミックス焼結体の製造方法 |
| US6949251B2 (en) | 2001-03-02 | 2005-09-27 | Stryker Corporation | Porous β-tricalcium phosphate granules for regeneration of bone tissue |
| JP4403268B2 (ja) * | 2001-10-21 | 2010-01-27 | 独立行政法人産業技術総合研究所 | リン酸カルシウム多孔質焼結体の製造方法及びそれを用いた人工骨の製造方法 |
| US7045105B2 (en) | 2001-12-21 | 2006-05-16 | Lagow Richard J | Calcium phosphate bone replacement materials and methods of use thereof |
| DE10201340A1 (de) * | 2002-01-16 | 2003-07-24 | Biovision Gmbh | Knochen-Ersatzmaterial und Verfahren zu seiner Herstellung |
| PT103866A (pt) * | 2007-10-25 | 2009-02-25 | Claudia Marina Souto Ranito | Método de fabrico de estruturas cerâmicas porosas à base de fosfatos de cálcio, alumina ou zircónia |
| WO2011143226A1 (fr) | 2010-05-11 | 2011-11-17 | Howmedica Osteonics Corp. | Composés métalliques multivalents organophosphorés et compositions de réseau interpénétrant d'adhésif polymère et procédés |
| US8765189B2 (en) | 2011-05-13 | 2014-07-01 | Howmedica Osteonic Corp. | Organophosphorous and multivalent metal compound compositions and methods |
| BR102012032608B1 (pt) * | 2012-12-18 | 2021-06-01 | Universidade Estadual De Campinas - Unicamp | Processo de obtenção de esponjas de hidroxiapatita e fosfato tricálcico, esponjas assim obtidas e uso das mesmas |
| CN105561386B (zh) * | 2016-01-29 | 2019-04-09 | 昆明理工大学 | 一种多孔羟基磷灰石/焦磷酸钙复合骨修复材料的制备方法 |
| CN107837419A (zh) * | 2016-09-20 | 2018-03-27 | 重庆润泽医药有限公司 | 一种多孔羟基磷灰石 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54138006A (en) * | 1978-04-19 | 1979-10-26 | Kyoto Ceramic | Bone break filling ceramic member |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2134695A1 (en) * | 1971-04-30 | 1972-12-08 | Mini En Electric | Homo-implants - made of human bone for treating parodontopathy |
| US3913229A (en) * | 1974-02-25 | 1975-10-21 | Miter Inc | Dental treatments |
| CH595293A5 (fr) * | 1975-02-20 | 1978-02-15 | Battelle Memorial Institute | |
| SE414399B (sv) * | 1976-03-16 | 1980-07-28 | Hans Scheicher | Keramiskt material for anvendning inom medicinen, i synnerhet for framstellning av implantat, fremst odontologiska implantat samt sett for framstellning av materialet |
| DE2840064C2 (de) * | 1978-09-14 | 1989-09-21 | Hans Dr.med. Dr.med.dent. 8000 München Scheicher | Verfahren zur Herstellung von Knochenkontaktschichten |
| JPS5654841A (en) * | 1979-10-08 | 1981-05-15 | Mitsubishi Mining & Cement Co | Bone broken portion and filler for void portion and method of treating bone of animal using said filler |
-
1980
- 1980-05-28 JP JP7006080A patent/JPS56166843A/ja active Granted
-
1981
- 1981-05-13 NL NLAANVRAGE8102354,A patent/NL182774C/xx not_active IP Right Cessation
- 1981-05-22 GB GB8115770A patent/GB2078696B/en not_active Expired
- 1981-05-27 DE DE3121182A patent/DE3121182C2/de not_active Expired
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54138006A (en) * | 1978-04-19 | 1979-10-26 | Kyoto Ceramic | Bone break filling ceramic member |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109133907A (zh) * | 2018-08-16 | 2019-01-04 | 迈海新型材料科技（固安）有限公司 | 一种包含羟基磷灰石晶须和双相钙磷的人工骨及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| NL8102354A (nl) | 1981-12-16 |
| GB2078696A (en) | 1982-01-13 |
| DE3121182A1 (de) | 1982-02-04 |
| NL182774C (nl) | 1988-05-16 |
| JPS56166843A (en) | 1981-12-22 |
| GB2078696B (en) | 1983-11-30 |
| DE3121182C2 (de) | 1985-10-10 |
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