JPH0575427B2 - - Google Patents
Info
- Publication number
- JPH0575427B2 JPH0575427B2 JP59200129A JP20012984A JPH0575427B2 JP H0575427 B2 JPH0575427 B2 JP H0575427B2 JP 59200129 A JP59200129 A JP 59200129A JP 20012984 A JP20012984 A JP 20012984A JP H0575427 B2 JPH0575427 B2 JP H0575427B2
- Authority
- JP
- Japan
- Prior art keywords
- particle size
- weight
- hydroxyapatite
- parts
- average particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000000988 bone and bone Anatomy 0.000 claims description 36
- 239000011148 porous material Substances 0.000 claims description 32
- 239000000463 material Substances 0.000 claims description 29
- 239000002245 particle Substances 0.000 claims description 17
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 15
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 14
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical group [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 8
- 239000001506 calcium phosphate Substances 0.000 claims description 7
- 238000005452 bending Methods 0.000 claims description 6
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 6
- 235000011010 calcium phosphates Nutrition 0.000 claims description 6
- 238000010304 firing Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000001913 cellulose Substances 0.000 description 7
- 229920002678 cellulose Polymers 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 229910052586 apatite Inorganic materials 0.000 description 6
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 6
- 239000008187 granular material Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- 230000007547 defect Effects 0.000 description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 2
- 239000012237 artificial material Substances 0.000 description 2
- 210000004373 mandible Anatomy 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 230000000399 orthopedic effect Effects 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 206010039203 Road traffic accident Diseases 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 210000000963 osteoblast Anatomy 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59200129A JPS6179462A (ja) | 1984-09-25 | 1984-09-25 | 多孔質人工骨材料 |
| US06/770,722 US4629464A (en) | 1984-09-25 | 1985-08-29 | Porous hydroxyapatite material for artificial bone substitute |
| DE19853531144 DE3531144A1 (de) | 1984-09-25 | 1985-08-30 | Poroeses hydroxyapatitmaterial und seine verwendung |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59200129A JPS6179462A (ja) | 1984-09-25 | 1984-09-25 | 多孔質人工骨材料 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6179462A JPS6179462A (ja) | 1986-04-23 |
| JPH0575427B2 true JPH0575427B2 (fr) | 1993-10-20 |
Family
ID=16419290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59200129A Granted JPS6179462A (ja) | 1984-09-25 | 1984-09-25 | 多孔質人工骨材料 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6179462A (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63125259A (ja) * | 1986-11-14 | 1988-05-28 | 旭光学工業株式会社 | リン酸カルシウム系多孔質骨補填材 |
| JP2657847B2 (ja) * | 1990-05-10 | 1997-09-30 | 寅雄 大塚 | 水酸化アパタイト多孔質生体充▲てん▼材並びにその製造方法 |
| JPH0440961A (ja) * | 1990-06-06 | 1992-02-12 | Mitsubishi Materials Corp | 骨欠損部及び骨空隙部ならびに骨吸収部充填材 |
| US6949251B2 (en) * | 2001-03-02 | 2005-09-27 | Stryker Corporation | Porous β-tricalcium phosphate granules for regeneration of bone tissue |
| JP2008173238A (ja) * | 2007-01-17 | 2008-07-31 | Olympus Terumo Biomaterials Corp | 生体組織補填材の製造方法 |
| WO2019163122A1 (fr) * | 2018-02-26 | 2019-08-29 | オリンパス株式会社 | Matériau de greffe osseuse et son procédé de fabrication |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56166843A (en) * | 1980-05-28 | 1981-12-22 | Mitsubishi Mining & Cement Co | Filler for bone broken section and void section |
-
1984
- 1984-09-25 JP JP59200129A patent/JPS6179462A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56166843A (en) * | 1980-05-28 | 1981-12-22 | Mitsubishi Mining & Cement Co | Filler for bone broken section and void section |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6179462A (ja) | 1986-04-23 |
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