JPH01500515A - B型肝炎ウィルス表面抗原のプレs領域のt及びb細胞エピトープ - Google Patents

B型肝炎ウィルス表面抗原のプレs領域のt及びb細胞エピトープ

Info

Publication number
JPH01500515A
JPH01500515A JP62504116A JP50411687A JPH01500515A JP H01500515 A JPH01500515 A JP H01500515A JP 62504116 A JP62504116 A JP 62504116A JP 50411687 A JP50411687 A JP 50411687A JP H01500515 A JPH01500515 A JP H01500515A
Authority
JP
Japan
Prior art keywords
polypeptide
region
hbsag
cell
terminal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62504116A
Other languages
English (en)
Japanese (ja)
Inventor
ミリッチ ディヴィッド アール
ソーントン ジョージ ビー
Original Assignee
スクリップス クリニック アンド リサーチ ファウンデーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by スクリップス クリニック アンド リサーチ ファウンデーション filed Critical スクリップス クリニック アンド リサーチ ファウンデーション
Publication of JPH01500515A publication Critical patent/JPH01500515A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP62504116A 1986-06-20 1987-06-18 B型肝炎ウィルス表面抗原のプレs領域のt及びb細胞エピトープ Pending JPH01500515A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87702086A 1986-06-20 1986-06-20
US877,020 1986-06-20
US6021487A 1987-06-10 1987-06-10
US060,214 1987-06-10

Publications (1)

Publication Number Publication Date
JPH01500515A true JPH01500515A (ja) 1989-02-23

Family

ID=26739692

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62504116A Pending JPH01500515A (ja) 1986-06-20 1987-06-18 B型肝炎ウィルス表面抗原のプレs領域のt及びb細胞エピトープ

Country Status (9)

Country Link
EP (1) EP0250253A3 (fi)
JP (1) JPH01500515A (fi)
CN (1) CN87105411A (fi)
AU (1) AU617292B2 (fi)
DK (1) DK88988A (fi)
FI (1) FI880802A0 (fi)
NZ (2) NZ232438A (fi)
PT (1) PT85137B (fi)
WO (1) WO1987007896A1 (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002532115A (ja) * 1998-12-19 2002-10-02 エムエル ラボラトリーズ ピーエルシー 異種移植片に対する寛容の改善

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126399A (en) * 1986-04-30 1992-06-30 Board Of Regents, The University Of Texas System Methods and compositions for the preparation and use of site-directed immunologic reagents
WO1988010301A1 (en) * 1987-06-22 1988-12-29 Mccormick And Jones Engineering Ltd. Hepatitis b surface antigen vaccine
DE10299017I2 (de) * 1987-06-22 2005-05-25 Medeva Holdings Bv Hepatitis-B-Oberfl{chenantigen enthaltendes Peptid.
EP0304578B1 (en) * 1987-06-22 2001-10-24 Medeva Holdings Bv Peptide comprising hepatitis B surface antigen
PT97632A (pt) * 1990-05-11 1992-03-31 Scripps Clinic Res Processo de obtencao de polipeptidos relacionados com a proteina do antigenio de superficie do virus da hepatite b e de vacinas que os contem
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
US5929220A (en) * 1995-07-21 1999-07-27 The General Hospital Corporation Hepadnavirus receptor
WO1998012332A1 (en) 1996-09-17 1998-03-26 Chiron Corporation Compositions and methods for treating intracellular diseases
EP1281761A1 (en) * 2001-07-27 2003-02-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Hepatitis B virus pre-S1 derived synthetic polypeptides and their use thereof.
WO2005050214A2 (en) * 2003-11-12 2005-06-02 Hbv Theranostica Ab Methods and means relating to hepatitis b infection
GB0326416D0 (en) 2003-11-12 2003-12-17 Karolinska Innovations Ab Methods and means relating to hepatitis B infection
JP2022547551A (ja) * 2019-09-11 2022-11-14 ザ ロックフェラー ユニバーシティー B型肝炎に対するヒト中和抗体に関連する組成物及び方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US4591552A (en) * 1982-09-29 1986-05-27 New York Blood Center, Inc. Detection of hepatitis B surface antigen (or antibody to same) with labeled synthetic peptide
US4847080A (en) * 1984-03-07 1989-07-11 New York Blood Center, Inc. Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipide vesicle carriers
US4599231A (en) * 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
WO1985004103A1 (en) * 1984-03-09 1985-09-26 Scripps Clinic And Research Foundation Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants
US4599230A (en) * 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002532115A (ja) * 1998-12-19 2002-10-02 エムエル ラボラトリーズ ピーエルシー 異種移植片に対する寛容の改善

Also Published As

Publication number Publication date
AU7640587A (en) 1988-01-12
EP0250253A2 (en) 1987-12-23
PT85137B (pt) 1990-03-08
FI880802A (fi) 1988-02-19
WO1987007896A1 (en) 1987-12-30
CN87105411A (zh) 1988-08-24
EP0250253A3 (en) 1989-03-22
AU617292B2 (en) 1991-11-28
NZ232438A (en) 1991-07-26
NZ220803A (en) 1990-03-27
DK88988D0 (da) 1988-02-19
DK88988A (da) 1988-04-20
PT85137A (en) 1987-07-01
FI880802A0 (fi) 1988-02-19

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