DK88988A - T- og b-celleepitoper af pre-s-regionen af hepatitis-b-virus-overfladeantigen - Google Patents

T- og b-celleepitoper af pre-s-regionen af hepatitis-b-virus-overfladeantigen

Info

Publication number
DK88988A
DK88988A DK088988A DK88988A DK88988A DK 88988 A DK88988 A DK 88988A DK 088988 A DK088988 A DK 088988A DK 88988 A DK88988 A DK 88988A DK 88988 A DK88988 A DK 88988A
Authority
DK
Denmark
Prior art keywords
hepatitis
region
surface antigen
cell epitopes
virus surface
Prior art date
Application number
DK088988A
Other languages
English (en)
Other versions
DK88988D0 (da
Inventor
David R Milich
George B Thornton
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK88988D0 publication Critical patent/DK88988D0/da
Publication of DK88988A publication Critical patent/DK88988A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK088988A 1986-06-20 1988-02-19 T- og b-celleepitoper af pre-s-regionen af hepatitis-b-virus-overfladeantigen DK88988A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87702086A 1986-06-20 1986-06-20
US6021487A 1987-06-10 1987-06-10
PCT/US1987/001505 WO1987007896A1 (en) 1986-06-20 1987-06-18 T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen

Publications (2)

Publication Number Publication Date
DK88988D0 DK88988D0 (da) 1988-02-19
DK88988A true DK88988A (da) 1988-04-20

Family

ID=26739692

Family Applications (1)

Application Number Title Priority Date Filing Date
DK088988A DK88988A (da) 1986-06-20 1988-02-19 T- og b-celleepitoper af pre-s-regionen af hepatitis-b-virus-overfladeantigen

Country Status (9)

Country Link
EP (1) EP0250253A3 (da)
JP (1) JPH01500515A (da)
CN (1) CN87105411A (da)
AU (1) AU617292B2 (da)
DK (1) DK88988A (da)
FI (1) FI880802A0 (da)
NZ (2) NZ220803A (da)
PT (1) PT85137B (da)
WO (1) WO1987007896A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126399A (en) * 1986-04-30 1992-06-30 Board Of Regents, The University Of Texas System Methods and compositions for the preparation and use of site-directed immunologic reagents
CA1341074C (en) * 1987-06-22 2000-08-08 Hans A. Thoma Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine
WO1988010301A1 (en) * 1987-06-22 1988-12-29 Mccormick And Jones Engineering Ltd. Hepatitis b surface antigen vaccine
EP1088830A3 (en) * 1987-06-22 2004-04-07 Medeva Holdings B.V. Hepatitis b surface antigen particles
PT97632A (pt) * 1990-05-11 1992-03-31 Scripps Clinic Res Processo de obtencao de polipeptidos relacionados com a proteina do antigenio de superficie do virus da hepatite b e de vacinas que os contem
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
US5929220A (en) * 1995-07-21 1999-07-27 The General Hospital Corporation Hepadnavirus receptor
EP0935659A1 (en) 1996-09-17 1999-08-18 Chiron Corporation Compositions and methods for treating intracellular diseases
CZ20011896A3 (cs) * 1998-12-19 2002-01-16 Ml Laboratories Plc Imunogenní prostředek a protilátka
EP1281761A1 (en) * 2001-07-27 2003-02-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Hepatitis B virus pre-S1 derived synthetic polypeptides and their use thereof.
GB0326416D0 (en) 2003-11-12 2003-12-17 Karolinska Innovations Ab Methods and means relating to hepatitis B infection
JP4486647B2 (ja) * 2003-11-12 2010-06-23 エイチビーヴイ セラノスティカ アクチエボラーグ Ｂ型肝炎感染症に関連する方法及び手段
CN111499722B (zh) 2012-11-12 2024-08-23 海德堡吕布莱希特-卡尔斯大学 用于治疗肝脏疾病和心血管疾病的脂肽
CA3154556A1 (en) * 2019-09-11 2021-03-18 The Rockefeller University Compositions and methods related to human neutralizing antibodies to hepatitis b

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US4591552A (en) * 1982-09-29 1986-05-27 New York Blood Center, Inc. Detection of hepatitis B surface antigen (or antibody to same) with labeled synthetic peptide
US4847080A (en) * 1984-03-07 1989-07-11 New York Blood Center, Inc. Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipide vesicle carriers
WO1985004103A1 (en) * 1984-03-09 1985-09-26 Scripps Clinic And Research Foundation Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants
US4599231A (en) * 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4599230A (en) * 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants

Also Published As

Publication number Publication date
FI880802A7 (fi) 1988-02-19
AU617292B2 (en) 1991-11-28
DK88988D0 (da) 1988-02-19
FI880802L (fi) 1988-02-19
PT85137A (en) 1987-07-01
FI880802A0 (fi) 1988-02-19
NZ220803A (en) 1990-03-27
EP0250253A3 (en) 1989-03-22
CN87105411A (zh) 1988-08-24
AU7640587A (en) 1988-01-12
EP0250253A2 (en) 1987-12-23
PT85137B (pt) 1990-03-08
WO1987007896A1 (en) 1987-12-30
JPH01500515A (ja) 1989-02-23
NZ232438A (en) 1991-07-26

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