JP7818585B2 - 癌を治療するための組み合わせ療法 - Google Patents

癌を治療するための組み合わせ療法

Info

Publication number
JP7818585B2
JP7818585B2 JP2023521357A JP2023521357A JP7818585B2 JP 7818585 B2 JP7818585 B2 JP 7818585B2 JP 2023521357 A JP2023521357 A JP 2023521357A JP 2023521357 A JP2023521357 A JP 2023521357A JP 7818585 B2 JP7818585 B2 JP 7818585B2
Authority
JP
Japan
Prior art keywords
cancer
pharmaceutically acceptable
azd5305
acceptable salt
chemotherapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2023521357A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023546362A5 (https=
JP2023546362A (ja
Inventor
レオ,エリザベッタ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of JP2023546362A publication Critical patent/JP2023546362A/ja
Publication of JP2023546362A5 publication Critical patent/JP2023546362A5/ja
Application granted granted Critical
Publication of JP7818585B2 publication Critical patent/JP7818585B2/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2023521357A 2020-10-08 2021-10-07 癌を治療するための組み合わせ療法 Active JP7818585B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063089195P 2020-10-08 2020-10-08
US63/089,195 2020-10-08
PCT/EP2021/077703 WO2022074124A1 (en) 2020-10-08 2021-10-07 Combination therapy for treating cancer

Publications (3)

Publication Number Publication Date
JP2023546362A JP2023546362A (ja) 2023-11-02
JP2023546362A5 JP2023546362A5 (https=) 2024-09-20
JP7818585B2 true JP7818585B2 (ja) 2026-02-20

Family

ID=78293953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023521357A Active JP7818585B2 (ja) 2020-10-08 2021-10-07 癌を治療するための組み合わせ療法

Country Status (19)

Country Link
US (1) US20230372333A1 (https=)
EP (1) EP4225297B1 (https=)
JP (1) JP7818585B2 (https=)
KR (1) KR20230083291A (https=)
CN (1) CN116194110B (https=)
AU (1) AU2021356123B2 (https=)
BR (1) BR112023005160A2 (https=)
CA (1) CA3197056A1 (https=)
DK (1) DK4225297T3 (https=)
ES (1) ES3005507T3 (https=)
FI (1) FI4225297T3 (https=)
HU (1) HUE069249T2 (https=)
IL (1) IL301687A (https=)
MX (1) MX2023004156A (https=)
PL (1) PL4225297T3 (https=)
PT (1) PT4225297T (https=)
TW (1) TW202228693A (https=)
WO (1) WO2022074124A1 (https=)
ZA (1) ZA202304965B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115702156A (zh) * 2021-04-23 2023-02-14 南京明德新药研发有限公司 吡啶酰胺类化合物
CN118119618A (zh) * 2021-09-09 2024-05-31 南京奥利墨斯医药科技有限公司 一种杂芳环类化合物及其应用
US20230250428A1 (en) * 2022-02-07 2023-08-10 Alliance Of Cardiovascular Researchers Method and composition for early detection of malignancies
IL316019A (en) * 2022-04-07 2024-11-01 Astrazeneca Ab Combined treatment for cancer
CN118973572A (zh) * 2022-04-07 2024-11-15 阿斯利康(瑞典)有限公司 用于治疗癌症的组合疗法
CN121464135A (zh) * 2023-07-07 2026-02-03 优领医药科技(香港)有限公司 含哌嗪并环类衍生物的晶型、其盐型、其制备方法及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022541483A (ja) 2019-07-19 2022-09-26 アストラゼネカ・アクチエボラーグ Parp1阻害薬

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015184145A1 (en) * 2014-05-28 2015-12-03 Eisai R&D Management Co., Ltd. Use of eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022541483A (ja) 2019-07-19 2022-09-26 アストラゼネカ・アクチエボラーグ Parp1阻害薬

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Phytomedicine,2018年,Vol.50,pp.88-98

Also Published As

Publication number Publication date
ZA202304965B (en) 2024-09-25
HUE069249T2 (hu) 2025-02-28
EP4225297A1 (en) 2023-08-16
CA3197056A1 (en) 2022-04-14
BR112023005160A2 (pt) 2023-04-18
MX2023004156A (es) 2023-05-03
CN116194110B (zh) 2025-06-17
DK4225297T3 (da) 2025-01-02
ES3005507T3 (en) 2025-03-14
AU2021356123A1 (en) 2023-06-08
PL4225297T3 (pl) 2025-03-17
TW202228693A (zh) 2022-08-01
KR20230083291A (ko) 2023-06-09
PT4225297T (pt) 2024-12-30
AU2021356123B2 (en) 2025-01-09
WO2022074124A1 (en) 2022-04-14
FI4225297T3 (fi) 2024-12-10
IL301687A (en) 2023-05-01
EP4225297B1 (en) 2024-10-23
JP2023546362A (ja) 2023-11-02
CN116194110A (zh) 2023-05-30
US20230372333A1 (en) 2023-11-23

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