TW202228693A - 用於治療癌症之組合療法 - Google Patents

用於治療癌症之組合療法 Download PDF

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Publication number
TW202228693A
TW202228693A TW110137116A TW110137116A TW202228693A TW 202228693 A TW202228693 A TW 202228693A TW 110137116 A TW110137116 A TW 110137116A TW 110137116 A TW110137116 A TW 110137116A TW 202228693 A TW202228693 A TW 202228693A
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TW
Taiwan
Prior art keywords
cancer
azd5305
pharmaceutically acceptable
acceptable salt
carboplatin
Prior art date
Application number
TW110137116A
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English (en)
Chinese (zh)
Inventor
伊麗莎貝塔 里奧
Original Assignee
瑞典商阿斯特捷利康公司
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Publication date
Application filed by 瑞典商阿斯特捷利康公司 filed Critical 瑞典商阿斯特捷利康公司
Publication of TW202228693A publication Critical patent/TW202228693A/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TW110137116A 2020-10-08 2021-10-06 用於治療癌症之組合療法 TW202228693A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063089195P 2020-10-08 2020-10-08
US63/089,195 2020-10-08

Publications (1)

Publication Number Publication Date
TW202228693A true TW202228693A (zh) 2022-08-01

Family

ID=78293953

Family Applications (1)

Application Number Title Priority Date Filing Date
TW110137116A TW202228693A (zh) 2020-10-08 2021-10-06 用於治療癌症之組合療法

Country Status (19)

Country Link
US (1) US20230372333A1 (https=)
EP (1) EP4225297B1 (https=)
JP (1) JP7818585B2 (https=)
KR (1) KR20230083291A (https=)
CN (1) CN116194110B (https=)
AU (1) AU2021356123B2 (https=)
BR (1) BR112023005160A2 (https=)
CA (1) CA3197056A1 (https=)
DK (1) DK4225297T3 (https=)
ES (1) ES3005507T3 (https=)
FI (1) FI4225297T3 (https=)
HU (1) HUE069249T2 (https=)
IL (1) IL301687A (https=)
MX (1) MX2023004156A (https=)
PL (1) PL4225297T3 (https=)
PT (1) PT4225297T (https=)
TW (1) TW202228693A (https=)
WO (1) WO2022074124A1 (https=)
ZA (1) ZA202304965B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115702156A (zh) * 2021-04-23 2023-02-14 南京明德新药研发有限公司 吡啶酰胺类化合物
CN118119618A (zh) * 2021-09-09 2024-05-31 南京奥利墨斯医药科技有限公司 一种杂芳环类化合物及其应用
US20230250428A1 (en) * 2022-02-07 2023-08-10 Alliance Of Cardiovascular Researchers Method and composition for early detection of malignancies
IL316019A (en) * 2022-04-07 2024-11-01 Astrazeneca Ab Combined treatment for cancer
CN118973572A (zh) * 2022-04-07 2024-11-15 阿斯利康(瑞典)有限公司 用于治疗癌症的组合疗法
CN121464135A (zh) * 2023-07-07 2026-02-03 优领医药科技(香港)有限公司 含哌嗪并环类衍生物的晶型、其盐型、其制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015184145A1 (en) * 2014-05-28 2015-12-03 Eisai R&D Management Co., Ltd. Use of eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer
SI3999506T1 (sl) * 2019-07-19 2025-06-30 Astrazeneca Ab Zaviralci PARP1

Also Published As

Publication number Publication date
ZA202304965B (en) 2024-09-25
HUE069249T2 (hu) 2025-02-28
JP7818585B2 (ja) 2026-02-20
EP4225297A1 (en) 2023-08-16
CA3197056A1 (en) 2022-04-14
BR112023005160A2 (pt) 2023-04-18
MX2023004156A (es) 2023-05-03
CN116194110B (zh) 2025-06-17
DK4225297T3 (da) 2025-01-02
ES3005507T3 (en) 2025-03-14
AU2021356123A1 (en) 2023-06-08
PL4225297T3 (pl) 2025-03-17
KR20230083291A (ko) 2023-06-09
PT4225297T (pt) 2024-12-30
AU2021356123B2 (en) 2025-01-09
WO2022074124A1 (en) 2022-04-14
FI4225297T3 (fi) 2024-12-10
IL301687A (en) 2023-05-01
EP4225297B1 (en) 2024-10-23
JP2023546362A (ja) 2023-11-02
CN116194110A (zh) 2023-05-30
US20230372333A1 (en) 2023-11-23

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