KR20230083291A - 암 치료를 위한 병용 요법 - Google Patents

암 치료를 위한 병용 요법 Download PDF

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Publication number
KR20230083291A
KR20230083291A KR1020237013320A KR20237013320A KR20230083291A KR 20230083291 A KR20230083291 A KR 20230083291A KR 1020237013320 A KR1020237013320 A KR 1020237013320A KR 20237013320 A KR20237013320 A KR 20237013320A KR 20230083291 A KR20230083291 A KR 20230083291A
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KR
South Korea
Prior art keywords
cancer
pharmaceutically acceptable
azd5305
acceptable salt
chemotherapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237013320A
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English (en)
Korean (ko)
Inventor
엘리자베타 레오
Original Assignee
아스트라제네카 아베
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아스트라제네카 아베 filed Critical 아스트라제네카 아베
Publication of KR20230083291A publication Critical patent/KR20230083291A/ko
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020237013320A 2020-10-08 2021-10-07 암 치료를 위한 병용 요법 Pending KR20230083291A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063089195P 2020-10-08 2020-10-08
US63/089,195 2020-10-08
PCT/EP2021/077703 WO2022074124A1 (en) 2020-10-08 2021-10-07 Combination therapy for treating cancer

Publications (1)

Publication Number Publication Date
KR20230083291A true KR20230083291A (ko) 2023-06-09

Family

ID=78293953

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237013320A Pending KR20230083291A (ko) 2020-10-08 2021-10-07 암 치료를 위한 병용 요법

Country Status (19)

Country Link
US (1) US20230372333A1 (https=)
EP (1) EP4225297B1 (https=)
JP (1) JP7818585B2 (https=)
KR (1) KR20230083291A (https=)
CN (1) CN116194110B (https=)
AU (1) AU2021356123B2 (https=)
BR (1) BR112023005160A2 (https=)
CA (1) CA3197056A1 (https=)
DK (1) DK4225297T3 (https=)
ES (1) ES3005507T3 (https=)
FI (1) FI4225297T3 (https=)
HU (1) HUE069249T2 (https=)
IL (1) IL301687A (https=)
MX (1) MX2023004156A (https=)
PL (1) PL4225297T3 (https=)
PT (1) PT4225297T (https=)
TW (1) TW202228693A (https=)
WO (1) WO2022074124A1 (https=)
ZA (1) ZA202304965B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115702156A (zh) * 2021-04-23 2023-02-14 南京明德新药研发有限公司 吡啶酰胺类化合物
CN118119618A (zh) * 2021-09-09 2024-05-31 南京奥利墨斯医药科技有限公司 一种杂芳环类化合物及其应用
US20230250428A1 (en) * 2022-02-07 2023-08-10 Alliance Of Cardiovascular Researchers Method and composition for early detection of malignancies
IL316019A (en) * 2022-04-07 2024-11-01 Astrazeneca Ab Combined treatment for cancer
CN118973572A (zh) * 2022-04-07 2024-11-15 阿斯利康(瑞典)有限公司 用于治疗癌症的组合疗法
CN121464135A (zh) * 2023-07-07 2026-02-03 优领医药科技(香港)有限公司 含哌嗪并环类衍生物的晶型、其盐型、其制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015184145A1 (en) * 2014-05-28 2015-12-03 Eisai R&D Management Co., Ltd. Use of eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer
SI3999506T1 (sl) * 2019-07-19 2025-06-30 Astrazeneca Ab Zaviralci PARP1

Also Published As

Publication number Publication date
ZA202304965B (en) 2024-09-25
HUE069249T2 (hu) 2025-02-28
JP7818585B2 (ja) 2026-02-20
EP4225297A1 (en) 2023-08-16
CA3197056A1 (en) 2022-04-14
BR112023005160A2 (pt) 2023-04-18
MX2023004156A (es) 2023-05-03
CN116194110B (zh) 2025-06-17
DK4225297T3 (da) 2025-01-02
ES3005507T3 (en) 2025-03-14
AU2021356123A1 (en) 2023-06-08
PL4225297T3 (pl) 2025-03-17
TW202228693A (zh) 2022-08-01
PT4225297T (pt) 2024-12-30
AU2021356123B2 (en) 2025-01-09
WO2022074124A1 (en) 2022-04-14
FI4225297T3 (fi) 2024-12-10
IL301687A (en) 2023-05-01
EP4225297B1 (en) 2024-10-23
JP2023546362A (ja) 2023-11-02
CN116194110A (zh) 2023-05-30
US20230372333A1 (en) 2023-11-23

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PA0105 International application

Patent event date: 20230419

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20241007

Comment text: Request for Examination of Application