CA3197056A1 - Combination therapy for treating cancer - Google Patents

Combination therapy for treating cancer

Info

Publication number
CA3197056A1
CA3197056A1 CA3197056A CA3197056A CA3197056A1 CA 3197056 A1 CA3197056 A1 CA 3197056A1 CA 3197056 A CA3197056 A CA 3197056A CA 3197056 A CA3197056 A CA 3197056A CA 3197056 A1 CA3197056 A1 CA 3197056A1
Authority
CA
Canada
Prior art keywords
cancer
azd5305
pharmaceutically acceptable
acceptable salt
carboplatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3197056A
Other languages
English (en)
French (fr)
Inventor
Elisabetta LEO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CA3197056A1 publication Critical patent/CA3197056A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA3197056A 2020-10-08 2021-10-07 Combination therapy for treating cancer Pending CA3197056A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063089195P 2020-10-08 2020-10-08
US63/089,195 2020-10-08
PCT/EP2021/077703 WO2022074124A1 (en) 2020-10-08 2021-10-07 Combination therapy for treating cancer

Publications (1)

Publication Number Publication Date
CA3197056A1 true CA3197056A1 (en) 2022-04-14

Family

ID=78293953

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3197056A Pending CA3197056A1 (en) 2020-10-08 2021-10-07 Combination therapy for treating cancer

Country Status (19)

Country Link
US (1) US20230372333A1 (https=)
EP (1) EP4225297B1 (https=)
JP (1) JP7818585B2 (https=)
KR (1) KR20230083291A (https=)
CN (1) CN116194110B (https=)
AU (1) AU2021356123B2 (https=)
BR (1) BR112023005160A2 (https=)
CA (1) CA3197056A1 (https=)
DK (1) DK4225297T3 (https=)
ES (1) ES3005507T3 (https=)
FI (1) FI4225297T3 (https=)
HU (1) HUE069249T2 (https=)
IL (1) IL301687A (https=)
MX (1) MX2023004156A (https=)
PL (1) PL4225297T3 (https=)
PT (1) PT4225297T (https=)
TW (1) TW202228693A (https=)
WO (1) WO2022074124A1 (https=)
ZA (1) ZA202304965B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115702156A (zh) * 2021-04-23 2023-02-14 南京明德新药研发有限公司 吡啶酰胺类化合物
CN118119618A (zh) * 2021-09-09 2024-05-31 南京奥利墨斯医药科技有限公司 一种杂芳环类化合物及其应用
US20230250428A1 (en) * 2022-02-07 2023-08-10 Alliance Of Cardiovascular Researchers Method and composition for early detection of malignancies
IL316019A (en) * 2022-04-07 2024-11-01 Astrazeneca Ab Combined treatment for cancer
CN118973572A (zh) * 2022-04-07 2024-11-15 阿斯利康(瑞典)有限公司 用于治疗癌症的组合疗法
CN121464135A (zh) * 2023-07-07 2026-02-03 优领医药科技(香港)有限公司 含哌嗪并环类衍生物的晶型、其盐型、其制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015184145A1 (en) * 2014-05-28 2015-12-03 Eisai R&D Management Co., Ltd. Use of eribulin and poly (adp ribose) polymerase (parp) inhibitors as combination therapy for the treatment of cancer
SI3999506T1 (sl) * 2019-07-19 2025-06-30 Astrazeneca Ab Zaviralci PARP1

Also Published As

Publication number Publication date
ZA202304965B (en) 2024-09-25
HUE069249T2 (hu) 2025-02-28
JP7818585B2 (ja) 2026-02-20
EP4225297A1 (en) 2023-08-16
BR112023005160A2 (pt) 2023-04-18
MX2023004156A (es) 2023-05-03
CN116194110B (zh) 2025-06-17
DK4225297T3 (da) 2025-01-02
ES3005507T3 (en) 2025-03-14
AU2021356123A1 (en) 2023-06-08
PL4225297T3 (pl) 2025-03-17
TW202228693A (zh) 2022-08-01
KR20230083291A (ko) 2023-06-09
PT4225297T (pt) 2024-12-30
AU2021356123B2 (en) 2025-01-09
WO2022074124A1 (en) 2022-04-14
FI4225297T3 (fi) 2024-12-10
IL301687A (en) 2023-05-01
EP4225297B1 (en) 2024-10-23
JP2023546362A (ja) 2023-11-02
CN116194110A (zh) 2023-05-30
US20230372333A1 (en) 2023-11-23

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