JP7814933B2 - 核酸化合物の製造方法、及び、核酸化合物 - Google Patents

核酸化合物の製造方法、及び、核酸化合物

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Publication number
JP7814933B2
JP7814933B2 JP2021543021A JP2021543021A JP7814933B2 JP 7814933 B2 JP7814933 B2 JP 7814933B2 JP 2021543021 A JP2021543021 A JP 2021543021A JP 2021543021 A JP2021543021 A JP 2021543021A JP 7814933 B2 JP7814933 B2 JP 7814933B2
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group
formula
carbon atoms
nucleic acid
aliphatic hydrocarbon
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English (en)
Japanese (ja)
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JPWO2021039935A1 (https=
JPWO2021039935A5 (https=
Inventor
和平 金子
基将 ▲高▼橋
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Fujifilm Corp
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Fujifilm Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021543021A 2019-08-29 2020-08-27 核酸化合物の製造方法、及び、核酸化合物 Active JP7814933B2 (ja)

Priority Applications (1)

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JP2023191159A JP7776478B2 (ja) 2019-08-29 2023-11-08 核酸化合物の製造方法、及び、核酸化合物

Applications Claiming Priority (3)

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JP2019157402 2019-08-29
JP2019157402 2019-08-29
PCT/JP2020/032476 WO2021039935A1 (ja) 2019-08-29 2020-08-27 核酸化合物の製造方法、及び、核酸化合物

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JPWO2021039935A1 JPWO2021039935A1 (https=) 2021-03-04
JPWO2021039935A5 JPWO2021039935A5 (https=) 2022-05-10
JP7814933B2 true JP7814933B2 (ja) 2026-02-17

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US (1) US12509484B2 (https=)
EP (1) EP4006045A4 (https=)
JP (2) JP7814933B2 (https=)
TW (1) TWI879793B (https=)
WO (1) WO2021039935A1 (https=)

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CN113508103A (zh) 2019-02-28 2021-10-15 富士胶片株式会社 肽化合物的制造方法、保护基形成用试药及稠合多环芳香族烃化合物
JP7628073B2 (ja) * 2019-02-28 2025-02-07 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、芳香族複素環化合物
JP7814933B2 (ja) 2019-08-29 2026-02-17 富士フイルム株式会社 核酸化合物の製造方法、及び、核酸化合物
EP4293035A4 (en) 2021-02-12 2025-03-05 Ajinomoto Co., Inc. METHOD FOR THE PRODUCTION OF OLIGONUCLEOTIDES
WO2024083746A1 (en) 2022-10-17 2024-04-25 Bachem Holding Ag Method and composition for oligonucleotide synthesis
EP4695265A1 (en) 2023-10-16 2026-02-18 Bachem Holding AG Method and composition for oligonucleotide synthesis
WO2025229953A1 (ja) * 2024-04-30 2025-11-06 住友化学株式会社 オリゴヌクレオチドの製造方法

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WO2016117663A1 (ja) 2015-01-21 2016-07-28 味の素株式会社 沈殿促進剤およびそれを用いる沈殿化方法
WO2017104836A1 (ja) 2015-12-16 2017-06-22 味の素株式会社 オリゴヌクレオチドの製造方法、およびヌクレオシド、ヌクレオチドまたはオリゴヌクレオチド
WO2018203574A1 (ja) 2017-05-02 2018-11-08 日産化学株式会社 オリゴヌクレオチドの製造方法
WO2018212236A1 (ja) 2017-05-16 2018-11-22 日産化学株式会社 オリゴヌクレオチドの製造方法

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JP7628073B2 (ja) 2019-02-28 2025-02-07 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、芳香族複素環化合物
WO2020262258A1 (ja) 2019-06-28 2020-12-30 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、縮合多環芳香族炭化水素化合物
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WO2012157723A1 (ja) 2011-05-17 2012-11-22 味の素株式会社 オリゴヌクレオチドの製造方法
WO2013179412A1 (ja) 2012-05-30 2013-12-05 北海道システム・サイエンス株式会社 高分散性液相支持体を用いたオリゴヌクレオチド合成法
WO2016117663A1 (ja) 2015-01-21 2016-07-28 味の素株式会社 沈殿促進剤およびそれを用いる沈殿化方法
WO2017104836A1 (ja) 2015-12-16 2017-06-22 味の素株式会社 オリゴヌクレオチドの製造方法、およびヌクレオシド、ヌクレオチドまたはオリゴヌクレオチド
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Also Published As

Publication number Publication date
JP7776478B2 (ja) 2025-11-26
TWI879793B (zh) 2025-04-11
JP2024009042A (ja) 2024-01-19
US20220259255A1 (en) 2022-08-18
JPWO2021039935A1 (https=) 2021-03-04
TW202115097A (zh) 2021-04-16
EP4006045A4 (en) 2022-10-19
US12509484B2 (en) 2025-12-30
EP4006045A1 (en) 2022-06-01
WO2021039935A1 (ja) 2021-03-04

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