JPWO2021039935A1 - - Google Patents

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Publication number
JPWO2021039935A1
JPWO2021039935A1 JP2021543021A JP2021543021A JPWO2021039935A1 JP WO2021039935 A1 JPWO2021039935 A1 JP WO2021039935A1 JP 2021543021 A JP2021543021 A JP 2021543021A JP 2021543021 A JP2021543021 A JP 2021543021A JP WO2021039935 A1 JPWO2021039935 A1 JP WO2021039935A1
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2021543021A
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Japanese (ja)
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JP7814933B2 (ja
JPWO2021039935A5 (https=
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Publication of JPWO2021039935A1 publication Critical patent/JPWO2021039935A1/ja
Publication of JPWO2021039935A5 publication Critical patent/JPWO2021039935A5/ja
Priority to JP2023191159A priority Critical patent/JP7776478B2/ja
Application granted granted Critical
Publication of JP7814933B2 publication Critical patent/JP7814933B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021543021A 2019-08-29 2020-08-27 核酸化合物の製造方法、及び、核酸化合物 Active JP7814933B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023191159A JP7776478B2 (ja) 2019-08-29 2023-11-08 核酸化合物の製造方法、及び、核酸化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019157402 2019-08-29
JP2019157402 2019-08-29
PCT/JP2020/032476 WO2021039935A1 (ja) 2019-08-29 2020-08-27 核酸化合物の製造方法、及び、核酸化合物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023191159A Division JP7776478B2 (ja) 2019-08-29 2023-11-08 核酸化合物の製造方法、及び、核酸化合物

Publications (3)

Publication Number Publication Date
JPWO2021039935A1 true JPWO2021039935A1 (https=) 2021-03-04
JPWO2021039935A5 JPWO2021039935A5 (https=) 2022-05-10
JP7814933B2 JP7814933B2 (ja) 2026-02-17

Family

ID=74684238

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021543021A Active JP7814933B2 (ja) 2019-08-29 2020-08-27 核酸化合物の製造方法、及び、核酸化合物
JP2023191159A Active JP7776478B2 (ja) 2019-08-29 2023-11-08 核酸化合物の製造方法、及び、核酸化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023191159A Active JP7776478B2 (ja) 2019-08-29 2023-11-08 核酸化合物の製造方法、及び、核酸化合物

Country Status (5)

Country Link
US (1) US12509484B2 (https=)
EP (1) EP4006045A4 (https=)
JP (2) JP7814933B2 (https=)
TW (1) TWI879793B (https=)
WO (1) WO2021039935A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113508103A (zh) 2019-02-28 2021-10-15 富士胶片株式会社 肽化合物的制造方法、保护基形成用试药及稠合多环芳香族烃化合物
JP7628073B2 (ja) * 2019-02-28 2025-02-07 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、芳香族複素環化合物
JP7814933B2 (ja) 2019-08-29 2026-02-17 富士フイルム株式会社 核酸化合物の製造方法、及び、核酸化合物
EP4293035A4 (en) 2021-02-12 2025-03-05 Ajinomoto Co., Inc. METHOD FOR THE PRODUCTION OF OLIGONUCLEOTIDES
WO2024083746A1 (en) 2022-10-17 2024-04-25 Bachem Holding Ag Method and composition for oligonucleotide synthesis
EP4695265A1 (en) 2023-10-16 2026-02-18 Bachem Holding AG Method and composition for oligonucleotide synthesis
WO2025229953A1 (ja) * 2024-04-30 2025-11-06 住友化学株式会社 オリゴヌクレオチドの製造方法

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WO2012157723A1 (ja) * 2011-05-17 2012-11-22 味の素株式会社 オリゴヌクレオチドの製造方法
WO2013179412A1 (ja) * 2012-05-30 2013-12-05 北海道システム・サイエンス株式会社 高分散性液相支持体を用いたオリゴヌクレオチド合成法
WO2016117663A1 (ja) * 2015-01-21 2016-07-28 味の素株式会社 沈殿促進剤およびそれを用いる沈殿化方法
WO2017104836A1 (ja) * 2015-12-16 2017-06-22 味の素株式会社 オリゴヌクレオチドの製造方法、およびヌクレオシド、ヌクレオチドまたはオリゴヌクレオチド
WO2018203574A1 (ja) * 2017-05-02 2018-11-08 日産化学株式会社 オリゴヌクレオチドの製造方法
WO2018212236A1 (ja) * 2017-05-16 2018-11-22 日産化学株式会社 オリゴヌクレオチドの製造方法

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US2825734A (en) 1955-04-11 1958-03-04 Upjohn Co Reduction of carbonylic radicals in indolyl-3 compounds
GB1456208A (en) 1972-12-28 1976-11-24 Agfa Gevaert Thermographic processes and recording material for use therein
JPS60252441A (ja) 1984-05-28 1985-12-13 Otsuka Pharmaceut Factory Inc ナフタレン及びナフトキノン誘導体
JP3312953B2 (ja) 1993-03-22 2002-08-12 財団法人生産開発科学研究所 ２位置側鎖を有するテトラフェニルポルフィリン金属錯体及びその製造法
WO1997032837A1 (en) 1996-03-06 1997-09-12 Sumitomo Pharmaceuticals Co., Ltd. Nonsteroidal estrogen derivatives
JP2000044493A (ja) 1998-07-27 2000-02-15 Asahi Chem Ind Co Ltd 化合物ライブラリー合成用保護基
SI21137A (sl) 2002-01-24 2003-08-31 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Derivati azafenilalanina
ES2615083T3 (es) 2005-09-20 2017-06-05 Jitsubo Co., Ltd. Vehículo de separación, método de separación de un compuesto, y método de síntesis del péptido utilizando el vehículo
ES2546808T3 (es) 2006-03-24 2015-09-28 Jitsubo Co., Ltd. Reactivo para síntesis orgánica y método de reacción de síntesis orgánica con dicho reactivo
EP2415744A4 (en) 2009-03-12 2014-03-19 Ajinomoto Kk FLUORENE COMPOUND
WO2010113939A1 (ja) 2009-03-30 2010-10-07 味の素株式会社 ジフェニルメタン化合物
JP5803674B2 (ja) 2009-12-25 2015-11-04 味の素株式会社 ベンジル化合物
KR102016198B1 (ko) 2012-04-25 2019-08-29 메르크 파텐트 게엠베하 공액 중합체
EP2921499B1 (en) 2012-11-14 2020-01-22 Takeda Pharmaceutical Company Limited Method for liquid-phase synthesis of nucleic acids
KR102375480B1 (ko) * 2014-04-30 2022-03-16 애질런트 테크놀로지스, 인크. 인 보호기 및 이의 제조 방법 및 용도
KR102630720B1 (ko) 2015-08-28 2024-01-29 세키스이 메디칼 가부시키가이샤 벤질 화합물
JP6853265B2 (ja) 2016-03-14 2021-03-31 ソマロジック, インコーポレイテッドSomaLogic, Inc. 核酸に組み込むための５−（ｎ−保護−トリプタミノカルボキシアミド）−２’−デオキシウリジンホスホロアミダイトの化合物及び合成方法
JP6283775B1 (ja) 2016-07-25 2018-02-21 積水メディカル株式会社 新規キサンテン保護剤
JP2019122489A (ja) 2018-01-12 2019-07-25 株式会社サンヤマト シャッターアセンブリおよびそれを用いた冷凍・冷蔵ショーケース
JP2019157402A (ja) 2018-03-08 2019-09-19 中井産業株式会社 木造軸組建築物の施工方法
JP6586218B2 (ja) 2018-12-06 2019-10-02 アルプスアルパイン株式会社 電流計測システム
CN113508103A (zh) 2019-02-28 2021-10-15 富士胶片株式会社 肽化合物的制造方法、保护基形成用试药及稠合多环芳香族烃化合物
JP7628073B2 (ja) 2019-02-28 2025-02-07 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、芳香族複素環化合物
WO2020262258A1 (ja) 2019-06-28 2020-12-30 富士フイルム株式会社 ペプチド化合物の製造方法、保護基形成用試薬、及び、縮合多環芳香族炭化水素化合物
JP7814933B2 (ja) 2019-08-29 2026-02-17 富士フイルム株式会社 核酸化合物の製造方法、及び、核酸化合物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012157723A1 (ja) * 2011-05-17 2012-11-22 味の素株式会社 オリゴヌクレオチドの製造方法
WO2013179412A1 (ja) * 2012-05-30 2013-12-05 北海道システム・サイエンス株式会社 高分散性液相支持体を用いたオリゴヌクレオチド合成法
WO2016117663A1 (ja) * 2015-01-21 2016-07-28 味の素株式会社 沈殿促進剤およびそれを用いる沈殿化方法
WO2017104836A1 (ja) * 2015-12-16 2017-06-22 味の素株式会社 オリゴヌクレオチドの製造方法、およびヌクレオシド、ヌクレオチドまたはオリゴヌクレオチド
WO2018203574A1 (ja) * 2017-05-02 2018-11-08 日産化学株式会社 オリゴヌクレオチドの製造方法
WO2018212236A1 (ja) * 2017-05-16 2018-11-22 日産化学株式会社 オリゴヌクレオチドの製造方法

Also Published As

Publication number Publication date
JP7776478B2 (ja) 2025-11-26
JP7814933B2 (ja) 2026-02-17
TWI879793B (zh) 2025-04-11
JP2024009042A (ja) 2024-01-19
US20220259255A1 (en) 2022-08-18
TW202115097A (zh) 2021-04-16
EP4006045A4 (en) 2022-10-19
US12509484B2 (en) 2025-12-30
EP4006045A1 (en) 2022-06-01
WO2021039935A1 (ja) 2021-03-04

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