JP7798811B2 - 抗ｂ７－ｈ３抗体を含む抗体－薬物コンジュゲート - Google Patents

抗ｂ７－ｈ３抗体を含む抗体－薬物コンジュゲート

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Publication number
JP7798811B2
JP7798811B2 JP2022580096A JP2022580096A JP7798811B2 JP 7798811 B2 JP7798811 B2 JP 7798811B2 JP 2022580096 A JP2022580096 A JP 2022580096A JP 2022580096 A JP2022580096 A JP 2022580096A JP 7798811 B2 JP7798811 B2 JP 7798811B2
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Japan
Prior art keywords
seq
amino acid
acid sequence
cancer
antibody
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JP2022580096A
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Japanese (ja)
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JP2023531252A5 (https=
JP2023531252A (ja
Inventor
パーク，デギョ
キム，スンヨン
パーク，スホ
ジュン，ドゥファン
ソ，ドンフン
リ，サングァン
ユン，サンヒョン
ハ，ジヒョン
リ，ヒャン，スク
パーク，オック
ソ，ボムソク
キム，セナ
ソル，ミナ
ソン，ジナ
ウ，スン，ホ
チョ，ジョンウン
リ，ジェホ
リ，ヒュン，ミ
ウン パーク，ジェ
ソ，ヨンジャ
リ，ウンジン
ジュ リ，ヒョン
シム，ウン－ヨン
コ，ユンジュン
リ，ミンジュ
パーク，ヨン，ウ
リュウ，ヨサプ
Original Assignee
イントゥーセル，インコーポレーティッド
ワイ－バイオロジクス インコーポレーテッド
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Publication of JP2023531252A publication Critical patent/JP2023531252A/ja
Publication of JP2023531252A5 publication Critical patent/JP2023531252A5/ja
Priority to JP2025283168A priority Critical patent/JP2026053657A/ja
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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BR112022026401A2 (pt) 2020-06-26 2023-03-14 Intocell Inc Conjugados anticorpo-fármaco compreendendo anticorpos anti-b7-h3
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JP2026508722A (ja) * 2022-10-28 2026-03-12 イーライ リリー アンド カンパニー バイオコンジュゲーションのための自己加水分解マレイミド
EP4680643A1 (en) * 2023-03-17 2026-01-21 Beone Medicines I GmbH Anti-b7h3 antibodies and methods of use
WO2024225838A1 (ko) * 2023-04-28 2024-10-31 주식회사 에이비켐바이오 균일한 dar을 갖는 말레이미드 함유 링커를 포함하는 항체-약물 중합체의 제조방법
WO2024235120A1 (zh) * 2023-05-12 2024-11-21 四川科伦博泰生物医药股份有限公司 稠环化合物及其制备方法和用途
CN116949044B (zh) * 2023-09-20 2023-12-12 北京炫景瑞医药科技有限公司 一种双链寡链核苷酸、包含该双链寡核苷酸的缀合物以及它们的用途
CN117777296B (zh) * 2024-02-28 2024-05-28 北京肿瘤医院(北京大学肿瘤医院) B7h3亲和体及其诊疗核素标记物的制备方法与应用
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