MX2019011117A - Anticuerpo b7-h3, fragmento de union a antigeno de los mismos y uso medico de los mismos. - Google Patents
Anticuerpo b7-h3, fragmento de union a antigeno de los mismos y uso medico de los mismos.Info
- Publication number
- MX2019011117A MX2019011117A MX2019011117A MX2019011117A MX2019011117A MX 2019011117 A MX2019011117 A MX 2019011117A MX 2019011117 A MX2019011117 A MX 2019011117A MX 2019011117 A MX2019011117 A MX 2019011117A MX 2019011117 A MX2019011117 A MX 2019011117A
- Authority
- MX
- Mexico
- Prior art keywords
- antigen
- antibody
- binding fragment
- medical use
- medicament
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 239000012634 fragment Substances 0.000 title abstract 4
- 101710185679 CD276 antigen Proteins 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 101000884279 Homo sapiens CD276 antigen Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 102000048770 human CD276 Human genes 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70532—B7 molecules, e.g. CD80, CD86
Abstract
La invención proporciona un anticuerpo B7-H3, un fragmento de unión a antígeno del mismo y un uso médico del mismo. Además, la presente invención describe una composición farmacéutica que comprende el anticuerpo B7-H3 o fragmento de unión a antígeno del mismo, y el uso del mismo como medicamento. En particular, la invención describe un uso de un anticuerpo B7-H3 humano o un fragmento de unión a antígeno del mismo para 10 la fabricación de un medicamento para el tratamiento de una enfermedad o afección asociada a B7-H3.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710206261 | 2017-03-31 | ||
PCT/CN2018/081249 WO2018177393A1 (zh) | 2017-03-31 | 2018-03-30 | B7-h3抗体、其抗原结合片段及其医药用途 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019011117A true MX2019011117A (es) | 2019-11-05 |
Family
ID=63674249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019011117A MX2019011117A (es) | 2017-03-31 | 2018-03-30 | Anticuerpo b7-h3, fragmento de union a antigeno de los mismos y uso medico de los mismos. |
Country Status (13)
Country | Link |
---|---|
US (2) | US10899837B2 (es) |
EP (1) | EP3604337A4 (es) |
JP (1) | JP7158403B2 (es) |
KR (1) | KR20190134614A (es) |
CN (1) | CN109937212B (es) |
AU (1) | AU2018243123A1 (es) |
BR (1) | BR112019019111A2 (es) |
CA (1) | CA3056474A1 (es) |
MX (1) | MX2019011117A (es) |
RU (1) | RU2765306C2 (es) |
TW (1) | TWI796328B (es) |
UA (1) | UA125593C2 (es) |
WO (1) | WO2018177393A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2018243123A1 (en) | 2017-03-31 | 2019-09-26 | Changzhou Hansoh Pharmaceutical Co., Ltd. | B7-H3 antibody, antigen-binding fragment thereof and medical use thereof |
TW201909926A (zh) * | 2017-08-04 | 2019-03-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | B7h3抗體-藥物偶聯物及其醫藥用途 |
US11403813B2 (en) | 2019-11-26 | 2022-08-02 | Sdc U.S. Smilepay Spv | Systems and methods for constructing a three-dimensional model from two-dimensional images |
US10916053B1 (en) | 2019-11-26 | 2021-02-09 | Sdc U.S. Smilepay Spv | Systems and methods for constructing a three-dimensional model from two-dimensional images |
US11270523B2 (en) | 2017-11-29 | 2022-03-08 | Sdc U.S. Smilepay Spv | Systems and methods for constructing a three-dimensional model from two-dimensional images |
WO2020018964A1 (en) | 2018-07-20 | 2020-01-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for controlled expression of antigen-specific receptors |
WO2020114479A1 (zh) * | 2018-12-07 | 2020-06-11 | 江苏恒瑞医药股份有限公司 | 多特异性蛋白分子 |
US11030801B2 (en) | 2019-05-17 | 2021-06-08 | Standard Cyborg, Inc. | Three-dimensional modeling toolkit |
KR20210006637A (ko) * | 2019-07-09 | 2021-01-19 | 주식회사 와이바이오로직스 | B7-h3(cd276)에 특이적으로 결합하는 항체 및 그의 용도 |
US20220332829A1 (en) * | 2019-09-16 | 2022-10-20 | Nanjing Sanhome Pharmaceutical Co., Ltd. | Anti-b7-h3 antibody and application thereof |
WO2021260438A1 (en) * | 2020-06-26 | 2021-12-30 | Intocell, Inc. | Antibody-drug conjugates comprising anti-b7-h3 antibodies |
CN115279417A (zh) * | 2021-02-09 | 2022-11-01 | 苏州宜联生物医药有限公司 | 生物活性物偶联物及其制备方法和用途 |
WO2022203414A1 (ko) * | 2021-03-26 | 2022-09-29 | 세라노틱스(주) | B7-h3 항체 또는 이의 항원 결합 단편 및 이의 용도 |
WO2023160376A1 (en) * | 2022-02-25 | 2023-08-31 | Nanjing Probio Biotech Co., Ltd. | Antibodies and variants thereof against human b7-h3 |
TW202402808A (zh) * | 2022-05-18 | 2024-01-16 | 中國大陸商上海藥明生物技術有限公司 | 抗-b7h3抗體及其用途 |
WO2023221975A1 (zh) * | 2022-05-18 | 2023-11-23 | 苏州宜联生物医药有限公司 | 包含蛋白降解剂类生物活性化合物的抗体药物偶联物及其制备方法和用途 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US20050002935A1 (en) * | 2003-04-17 | 2005-01-06 | Vincent Ling | Use of B7-H3 as an immunoregulatory agent |
CN101104639A (zh) | 2006-07-10 | 2008-01-16 | 苏州大学 | 抗人b7-h3单克隆抗体的制备及其应用 |
CA2668800A1 (en) | 2006-11-08 | 2008-06-05 | Macrogenics West, Inc. | Tes7 and antibodies that bind thereto |
US20100203035A1 (en) | 2007-02-14 | 2010-08-12 | Kwon Eugene D | B7-h3 in cancer |
CA2729593A1 (en) | 2009-02-20 | 2010-08-26 | John Wayne Cancer Institute | B7-h3 as a biomarker for diagnosing the progression and early lymph node metastasis of cancer |
US8802091B2 (en) * | 2010-03-04 | 2014-08-12 | Macrogenics, Inc. | Antibodies reactive with B7-H3 and uses thereof |
PL2542256T3 (pl) * | 2010-03-04 | 2020-01-31 | Macrogenics, Inc. | Przeciwciała reaktywne wobec b7-h3, ich immunologicznie czynne fragmenty i ich zastosowania |
PT2703486T (pt) | 2011-04-25 | 2018-05-18 | Daiichi Sankyo Co Ltd | Anticorpo anti-b7-h3 |
US9790282B2 (en) * | 2013-03-25 | 2017-10-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-CD276 polypeptides, proteins, and chimeric antigen receptors |
CA2947660C (en) | 2014-05-29 | 2021-06-29 | Spring Bioscience Corporation | Anti-b7-h3 antibodies and diagnostic uses thereof |
EA038798B1 (ru) | 2014-08-27 | 2021-10-21 | Мемориал Слоан-Кеттеринг Кэнсер Сентер | Анти-b7h3 антитела и связанные соединения и применение |
ES2875057T3 (es) | 2014-09-17 | 2021-11-08 | Us Health | Anticuerpos anti-CD276 (B7H3) |
AU2018243123A1 (en) | 2017-03-31 | 2019-09-26 | Changzhou Hansoh Pharmaceutical Co., Ltd. | B7-H3 antibody, antigen-binding fragment thereof and medical use thereof |
-
2018
- 2018-03-30 AU AU2018243123A patent/AU2018243123A1/en active Pending
- 2018-03-30 KR KR1020197027386A patent/KR20190134614A/ko active IP Right Grant
- 2018-03-30 TW TW107111275A patent/TWI796328B/zh active
- 2018-03-30 UA UAA201910562A patent/UA125593C2/uk unknown
- 2018-03-30 US US16/497,687 patent/US10899837B2/en active Active
- 2018-03-30 EP EP18776535.9A patent/EP3604337A4/en active Pending
- 2018-03-30 WO PCT/CN2018/081249 patent/WO2018177393A1/zh active Application Filing
- 2018-03-30 BR BR112019019111A patent/BR112019019111A2/pt unknown
- 2018-03-30 RU RU2019132843A patent/RU2765306C2/ru active
- 2018-03-30 CN CN201880004340.8A patent/CN109937212B/zh active Active
- 2018-03-30 CA CA3056474A patent/CA3056474A1/en active Pending
- 2018-03-30 MX MX2019011117A patent/MX2019011117A/es unknown
- 2018-03-30 JP JP2019552850A patent/JP7158403B2/ja active Active
-
2020
- 2020-12-15 US US17/121,893 patent/US11680100B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3604337A1 (en) | 2020-02-05 |
US20200031934A1 (en) | 2020-01-30 |
EP3604337A4 (en) | 2021-03-10 |
KR20190134614A (ko) | 2019-12-04 |
CN109937212A (zh) | 2019-06-25 |
RU2765306C2 (ru) | 2022-01-28 |
TW201837056A (zh) | 2018-10-16 |
CN109937212B (zh) | 2022-06-21 |
US11680100B2 (en) | 2023-06-20 |
WO2018177393A1 (zh) | 2018-10-04 |
TWI796328B (zh) | 2023-03-21 |
US20210101984A1 (en) | 2021-04-08 |
CA3056474A1 (en) | 2018-10-04 |
JP7158403B2 (ja) | 2022-10-21 |
US10899837B2 (en) | 2021-01-26 |
JP2020515251A (ja) | 2020-05-28 |
AU2018243123A1 (en) | 2019-09-26 |
RU2019132843A (ru) | 2021-04-30 |
UA125593C2 (uk) | 2022-04-27 |
BR112019019111A2 (pt) | 2020-05-05 |
RU2019132843A3 (es) | 2021-08-16 |
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