CN115279417A - 生物活性物偶联物及其制备方法和用途 - Google Patents

生物活性物偶联物及其制备方法和用途 Download PDF

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CN115279417A
CN115279417A CN202280003045.7A CN202280003045A CN115279417A CN 115279417 A CN115279417 A CN 115279417A CN 202280003045 A CN202280003045 A CN 202280003045A CN 115279417 A CN115279417 A CN 115279417A
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seq
sequence
antibody
antigen
binding fragment
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蔡家强
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Suzhou Yilian Biomedical Co ltd
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Suzhou Yilian Biomedical Co ltd
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    • A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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Abstract

本公开涉及生物活性物偶联物及其制备方法和用途,具体公开了式XV所示的配体药物偶联物、其制备方法,以及其在预防和/或治疗与细胞活动异常相关的疾病,包括但不限于在预防和/或治疗肿瘤疾病中的用途。

Description

PCT国内申请,说明书已公开。

Claims (51)

  1. PCT国内申请,权利要求书已公开。
CN202280003045.7A 2021-02-09 2022-01-25 生物活性物偶联物及其制备方法和用途 Pending CN115279417A (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
CN2021101781361 2021-02-09
CN202110178136 2021-02-09
CN202110340806 2021-03-30
CN2021103408065 2021-03-30
CN202110825906 2021-07-21
CN202110825932 2021-07-21
CN202110825922 2021-07-21
CN202110825932X 2021-07-21
CN2021108259067 2021-07-21
CN2021108259226 2021-07-21
PCT/CN2022/073822 WO2022170971A1 (zh) 2021-02-09 2022-01-25 生物活性物偶联物及其制备方法和用途

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CN115279417A true CN115279417A (zh) 2022-11-01

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US (1) US20240108745A1 (zh)
EP (1) EP4257154A1 (zh)
JP (1) JP2024508081A (zh)
KR (1) KR20230145038A (zh)
CN (1) CN115279417A (zh)
AU (1) AU2022220512A1 (zh)
CA (1) CA3206117A1 (zh)
IL (1) IL304804A (zh)
MX (1) MX2023008895A (zh)
TW (1) TW202241521A (zh)
WO (1) WO2022170971A1 (zh)

Cited By (1)

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