JP7572371B2 - 養子移入療法(Adoptive transfer therapies)におけるTリンパ球及びNK細胞の拡大増殖及び分化のための方法 - Google Patents
養子移入療法(Adoptive transfer therapies)におけるTリンパ球及びNK細胞の拡大増殖及び分化のための方法 Download PDFInfo
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- JP7572371B2 JP7572371B2 JP2021555590A JP2021555590A JP7572371B2 JP 7572371 B2 JP7572371 B2 JP 7572371B2 JP 2021555590 A JP2021555590 A JP 2021555590A JP 2021555590 A JP2021555590 A JP 2021555590A JP 7572371 B2 JP7572371 B2 JP 7572371B2
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K40/00—Cellular immunotherapy
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- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4271—Melanoma antigens
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/57—Skin; melanoma
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C12N2501/2302—Interleukin-2 (IL-2)
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- C12N2501/20—Cytokines; Chemokines
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- C12N2501/20—Cytokines; Chemokines
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2317—Interleukin-17 (IL-17)
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- C12N2501/20—Cytokines; Chemokines
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/10041—Use of virus, viral particle or viral elements as a vector
- C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
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- Hematology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Plant Pathology (AREA)
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- Molecular Biology (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Developmental Biology & Embryology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Oncology (AREA)
- Mycology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU2019000021A CU24712B1 (es) | 2019-03-15 | 2019-03-15 | Método para la expansión y diferenciación de linfocitos t y células nk en terapias de transferencia adoptiva |
| CUCU-2019-0021 | 2019-03-15 | ||
| PCT/CU2020/050002 WO2020187340A2 (es) | 2019-03-15 | 2020-03-09 | Método para la expansión y diferenciación de linfocitos t y células nk en terapias de transferencia adoptiva |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022524882A JP2022524882A (ja) | 2022-05-10 |
| JP2022524882A5 JP2022524882A5 (https=) | 2023-01-27 |
| JP7572371B2 true JP7572371B2 (ja) | 2024-10-23 |
Family
ID=72087852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021555590A Active JP7572371B2 (ja) | 2019-03-15 | 2020-03-09 | 養子移入療法(Adoptive transfer therapies)におけるTリンパ球及びNK細胞の拡大増殖及び分化のための方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20220152107A1 (https=) |
| EP (1) | EP3940063A2 (https=) |
| JP (1) | JP7572371B2 (https=) |
| KR (1) | KR20220012224A (https=) |
| CN (1) | CN113785048B (https=) |
| AR (1) | AR118369A1 (https=) |
| AU (1) | AU2020242520B2 (https=) |
| BR (1) | BR112021018100A2 (https=) |
| CA (1) | CA3133736A1 (https=) |
| CO (1) | CO2021013127A2 (https=) |
| CU (1) | CU24712B1 (https=) |
| EA (1) | EA202192447A1 (https=) |
| MX (1) | MX2021011120A (https=) |
| MY (1) | MY206651A (https=) |
| SG (1) | SG11202109574QA (https=) |
| TW (1) | TW202102667A (https=) |
| WO (1) | WO2020187340A2 (https=) |
| ZA (1) | ZA202107758B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL276365B2 (en) | 2018-02-01 | 2023-10-01 | Nkmax Co Ltd | A method for the production of natural killer cells and a preparation for cancer treatment |
| US12473336B2 (en) | 2018-02-21 | 2025-11-18 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses thereof |
| CA3158133A1 (en) | 2020-04-28 | 2021-11-04 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| TW202406932A (zh) | 2020-10-22 | 2024-02-16 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
| WO2023004004A1 (en) * | 2021-07-23 | 2023-01-26 | Merck Sharp & Dohme Llc | Il-2 muteins for treating cancer or infection |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009053109A1 (en) | 2007-10-24 | 2009-04-30 | Anne Letsch | Antigen-specific t-cell preparations from bone marrow |
| JP2014500868A (ja) | 2010-11-12 | 2014-01-16 | セントロ ド インムノロジア モレキュラー | 癌及び慢性感染の治療のための作動薬活性を有するil−2由来のポリペプチド |
| WO2017136818A2 (en) | 2016-02-05 | 2017-08-10 | Washington University | Compositions and methods for targeted cytokine delivery |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1956080E (pt) * | 2005-08-08 | 2011-12-30 | San Raffaele Centro Fond | Uso de il-7 e il-15 para a modificação genética de linfócitos t da memória |
| JP2015524255A (ja) * | 2012-07-13 | 2015-08-24 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 二重特異性抗体を共導入することによってcart細胞の活性を強化する方法 |
-
2019
- 2019-03-15 CU CU2019000021A patent/CU24712B1/es unknown
-
2020
- 2020-03-09 WO PCT/CU2020/050002 patent/WO2020187340A2/es not_active Ceased
- 2020-03-09 JP JP2021555590A patent/JP7572371B2/ja active Active
- 2020-03-09 SG SG11202109574Q patent/SG11202109574QA/en unknown
- 2020-03-09 US US17/439,293 patent/US20220152107A1/en active Pending
- 2020-03-09 EA EA202192447A patent/EA202192447A1/ru unknown
- 2020-03-09 MX MX2021011120A patent/MX2021011120A/es unknown
- 2020-03-09 AU AU2020242520A patent/AU2020242520B2/en active Active
- 2020-03-09 MY MYPI2021005276A patent/MY206651A/en unknown
- 2020-03-09 CA CA3133736A patent/CA3133736A1/en active Pending
- 2020-03-09 CN CN202080020973.5A patent/CN113785048B/zh active Active
- 2020-03-09 KR KR1020217033073A patent/KR20220012224A/ko not_active Ceased
- 2020-03-09 BR BR112021018100A patent/BR112021018100A2/pt unknown
- 2020-03-09 EP EP20757209.0A patent/EP3940063A2/en active Pending
- 2020-03-12 TW TW109108199A patent/TW202102667A/zh unknown
- 2020-03-13 AR ARP200100724A patent/AR118369A1/es unknown
-
2021
- 2021-09-30 CO CONC2021/0013127A patent/CO2021013127A2/es unknown
- 2021-10-13 ZA ZA2021/07758A patent/ZA202107758B/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009053109A1 (en) | 2007-10-24 | 2009-04-30 | Anne Letsch | Antigen-specific t-cell preparations from bone marrow |
| JP2014500868A (ja) | 2010-11-12 | 2014-01-16 | セントロ ド インムノロジア モレキュラー | 癌及び慢性感染の治療のための作動薬活性を有するil−2由来のポリペプチド |
| WO2017136818A2 (en) | 2016-02-05 | 2017-08-10 | Washington University | Compositions and methods for targeted cytokine delivery |
Non-Patent Citations (3)
| Title |
|---|
| BLAESCHKE, F. et al.,Induction of a central memory and stem cell memory phenotype in functionally active CD4+ and CD8+ CAR T cells produced in an automated good manufacturing practice system for the treatment of CD19+ acute lymphoblastic leukemia,Cancer Immunology, Immunotherapy,2018年,Vol. 67, No. 7,P. 1053-1066,DOI: 10.1007/s00262-018-2155-7 |
| HALLETT, W. H. D. et al.,Combination Therapy Using IL-2 and Anti-CD25 Results in Augmented Natural Killer Cell-Mediated Antitumor Responses,Biology of Blood and Marrow Transplantation,2008年10月,Vol. 14, Iss. 10,P. 1088-1099,https://doi.org/10.1016/j.bbmt.2008.08.001 |
| RAJAGOPALAN, A. et al.,Aptamer-Targeted Attenuation of IL-2 Signaling in CD8+ T Cells Enhances Antitumor Immunity,Molecular Therapy,2017年,Vol. 25, No. 1,P. 54-61,https://doi.org/10.1016/j.ymthe.2016.10.021 |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2021011120A (es) | 2022-01-18 |
| MY206651A (en) | 2024-12-30 |
| JP2022524882A (ja) | 2022-05-10 |
| CN113785048B (zh) | 2024-09-24 |
| AR118369A1 (es) | 2021-09-29 |
| EP3940063A2 (en) | 2022-01-19 |
| ZA202107758B (en) | 2022-12-21 |
| CO2021013127A2 (es) | 2022-03-18 |
| CU20190021A7 (es) | 2020-10-20 |
| CA3133736A1 (en) | 2020-09-24 |
| EA202192447A1 (ru) | 2021-12-07 |
| TW202102667A (zh) | 2021-01-16 |
| KR20220012224A (ko) | 2022-02-03 |
| CN113785048A (zh) | 2021-12-10 |
| AU2020242520A1 (en) | 2021-11-11 |
| AU2020242520B2 (en) | 2024-04-04 |
| CU24712B1 (es) | 2024-07-10 |
| WO2020187340A2 (es) | 2020-09-24 |
| BR112021018100A2 (pt) | 2022-02-08 |
| US20220152107A1 (en) | 2022-05-19 |
| WO2020187340A3 (es) | 2021-04-15 |
| SG11202109574QA (en) | 2021-10-28 |
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