JP7558156B2 - エキサテカン類似体のリガンド－薬物コンジュゲート、その調製方法およびその適用 - Google Patents

エキサテカン類似体のリガンド－薬物コンジュゲート、その調製方法およびその適用 Download PDF

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JP7558156B2
JP7558156B2 JP2021516798A JP2021516798A JP7558156B2 JP 7558156 B2 JP7558156 B2 JP 7558156B2 JP 2021516798 A JP2021516798 A JP 2021516798A JP 2021516798 A JP2021516798 A JP 2021516798A JP 7558156 B2 JP7558156 B2 JP 7558156B2
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cancer
antibody
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JP2022511351A (ja
JP2022511351A5 (https=
JPWO2020063676A5 (https=
Inventor
ジェンイェン シイ
イン チャン
シャオファン ツァイ
ボーレイ チュー
ジンドン リャン
リアンシャン チャン
フェン ヘ
ウェイカン タオ
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Jiangsu Hengrui Medicine Co Ltd
Shanghai Hengrui Pharmaceutical Co Ltd
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Jiangsu Hengrui Medicine Co Ltd
Shanghai Hengrui Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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  • Genetics & Genomics (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2021516798A 2018-09-26 2019-09-25 エキサテカン類似体のリガンド－薬物コンジュゲート、その調製方法およびその適用 Active JP7558156B2 (ja)

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CN201811123833.1 2018-09-26
CN201811123833 2018-09-26
PCT/CN2019/107873 WO2020063676A1 (zh) 2018-09-26 2019-09-25 依喜替康类似物的配体-药物偶联物及其制备方法和应用

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JP2022511351A JP2022511351A (ja) 2022-01-31
JP2022511351A5 JP2022511351A5 (https=) 2022-10-03
JPWO2020063676A5 JPWO2020063676A5 (https=) 2022-10-03
JP7558156B2 true JP7558156B2 (ja) 2024-09-30

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