JP7510413B2 - Ｂ細胞成熟抗原に特異的なキメラ抗原受容体を使用する処置方法 - Google Patents

Ｂ細胞成熟抗原に特異的なキメラ抗原受容体を使用する処置方法 Download PDF

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JP7510413B2
JP7510413B2 JP2021524037A JP2021524037A JP7510413B2 JP 7510413 B2 JP7510413 B2 JP 7510413B2 JP 2021524037 A JP2021524037 A JP 2021524037A JP 2021524037 A JP2021524037 A JP 2021524037A JP 7510413 B2 JP7510413 B2 JP 7510413B2
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ブライズ ディー． サザー
エリック エル． スミス
セミフ タリーン
エイ チェン
イムス シール ディ
エリック ヘス
オードリー オルシェフスキー
ステファン ポンコ
マリアナ コタ シュティルナー
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ジュノー セラピューティクス インコーポレイテッド
メモリアル スローン ケタリング キャンサー センター
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JP2021524037A 2018-11-01 2019-10-31 Ｂ細胞成熟抗原に特異的なキメラ抗原受容体を使用する処置方法 Active JP7510413B2 (ja)

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Application Number Priority Date Filing Date Title
US201862754577P 2018-11-01 2018-11-01
US62/754,577 2018-11-01
US201862774167P 2018-11-30 2018-11-30
US62/774,167 2018-11-30
US201862774856P 2018-12-03 2018-12-03
US62/774,856 2018-12-03
US201862777066P 2018-12-07 2018-12-07
US62/777,066 2018-12-07
US201962845817P 2019-05-09 2019-05-09
US62/845,817 2019-05-09
PCT/US2019/059271 WO2020092848A2 (en) 2018-11-01 2019-10-31 Methods for treatment using chimeric antigen receptors specific for b-cell maturation antigen

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US11066475B2 (en) 2017-11-01 2021-07-20 Juno Therapeutics, Inc. Chimeric antigen receptors specific for B-cell maturation antigen and encoding polynucleotides
US11851679B2 (en) 2017-11-01 2023-12-26 Juno Therapeutics, Inc. Method of assessing activity of recombinant antigen receptors
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CN119193493A (zh) 2017-12-08 2024-12-27 朱诺治疗学股份有限公司 生产工程化t细胞组合物的过程
US12473345B2 (en) 2018-11-01 2025-11-18 Juno Therapeutics, Inc. Methods for treatment using chimeric antigen receptors specific for B-cell maturation antigen
CN113573719A (zh) 2018-11-08 2021-10-29 朱诺治疗学股份有限公司 治疗和t细胞调节的方法和组合
CA3140102A1 (en) * 2019-05-30 2020-12-03 Dina SCHNEIDER Compositions and methods for treating cancer with anti-bcma immunotherapy
AU2020397170A1 (en) * 2019-12-05 2022-07-21 Sanofi-Aventis U.S. Llc Formulations of anti-CD38 antibodies for subcutaneous administration
WO2021113776A1 (en) 2019-12-06 2021-06-10 Juno Therapeutics, Inc. Anti-idiotypic antibodies to bcma-targeted binding domains and related compositions and methods
CA3181399A1 (en) * 2020-04-28 2021-11-04 Juno Therapeutics, Inc. Combination of bcma-directed t cell therapy and an immunomodulatory compound
JP2023525049A (ja) * 2020-05-08 2023-06-14 シアトル・チルドレンズ・ホスピタル・ドゥーイング／ビジネス／アズ・シアトル・チルドレンズ・リサーチ・インスティテュート ナチュラルキラー細胞を標的とするキメラ抗原受容体（ｃａｒ）
KR20230024283A (ko) 2020-05-13 2023-02-20 주노 쎄러퓨티크스 인코퍼레이티드 임상 반응과 관련된 특징을 식별하는 방법 및 이의 용도
IL308345A (en) * 2021-05-11 2024-01-01 Janssen Biotech Inc Methods for Minimizing Neurotoxicity Associated with Chimeric Antigen Receptor (CAR) T Cell Therapy
AU2022301978A1 (en) * 2021-06-28 2024-01-25 Meridian Therapeutics, Inc. Compositions and methods of treating plasma cell disorders including multiple myeloma with a vaccine composition and myeloma-specific car-t cells
MX2024002590A (es) 2021-09-01 2024-03-22 Springworks Therapeutics Inc Sintesis de nirogacestat.
US20250345432A1 (en) 2022-05-25 2025-11-13 Celgene Corporation Method for predicting response to a t cell therapy
WO2026074086A1 (en) * 2024-10-02 2026-04-09 Fundación Para La Investigación Médica Aplicada Cells expressing chimeric antigen receptors and a glutamine transporter, uses and methods thereof

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