JP7355473B1 - 循環腫瘍細胞分離キット、循環腫瘍細胞分離容器及び循環腫瘍細胞の分離方法 - Google Patents

循環腫瘍細胞分離キット、循環腫瘍細胞分離容器及び循環腫瘍細胞の分離方法 Download PDF

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JP7355473B1
JP7355473B1 JP2023545876A JP2023545876A JP7355473B1 JP 7355473 B1 JP7355473 B1 JP 7355473B1 JP 2023545876 A JP2023545876 A JP 2023545876A JP 2023545876 A JP2023545876 A JP 2023545876A JP 7355473 B1 JP7355473 B1 JP 7355473B1
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circulating tumor
cell separation
blood
tumor cell
aqueous solution
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JPWO2023181468A5 (https=
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嵩也 内山
まりか 神田
邦哉 駒井
智雅 井上
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Sekisui Medical Co Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0694—Cells of blood, e.g. leukemia cells, myeloma cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • C—CHEMISTRY; METALLURGY
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    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
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    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

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  • Health & Medical Sciences (AREA)
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  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2023545876A 2022-03-25 2022-10-17 循環腫瘍細胞分離キット、循環腫瘍細胞分離容器及び循環腫瘍細胞の分離方法 Active JP7355473B1 (ja)

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JP2022049652 2022-03-25
JP2022049652 2022-03-25
PCT/JP2022/038554 WO2023181468A1 (ja) 2022-03-25 2022-10-17 循環腫瘍細胞分離キット、循環腫瘍細胞分離容器及び循環腫瘍細胞の分離方法

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EP (1) EP4502599A1 (https=)
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024070504A1 (ja) * 2022-09-29 2024-04-04 積水メディカル株式会社 血液保存用組成物及び血液採取容器

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01199158A (ja) * 1987-10-20 1989-08-10 Seitetsu Kagaku Co Ltd 赤血球保存液
JP2005501236A (ja) * 2001-08-23 2005-01-13 イムニベスト・コーポレイション 分析用の細胞および生物学的検体の安定化
JP2007271388A (ja) * 2006-03-30 2007-10-18 Hidetoshi Tsuchida 血清または血漿の分離方法および血液分離管
WO2013168767A1 (ja) * 2012-05-10 2013-11-14 コニカミノルタ株式会社 赤血球除去方法および採血用遠沈管
JP2014524027A (ja) * 2011-07-05 2014-09-18 ベクトン・ディキンソン・アンド・カンパニー 凝固制御剤およびそれを含む装置
JP2015506482A (ja) * 2012-02-02 2015-03-02 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 血液安定剤を含んだサンプル採取器具
WO2015046557A1 (ja) * 2013-09-30 2015-04-02 積水メディカル株式会社 循環腫瘍細胞濃縮分離デバイス及び循環腫瘍細胞の濃縮分離方法
JP2019211216A (ja) * 2018-05-31 2019-12-12 アークレイ株式会社 血液中の稀少細胞検査、該検査ための血液処理方法及び採血管
JP2020523577A (ja) * 2017-06-13 2020-08-06 スン・チュン・チンＣｈｕｎｇ Ｃｈｉｎ ＳＵＮ 新規な血清タンパク質の活性の保存方法
JP2021500585A (ja) * 2017-10-19 2021-01-07 ストレック， インコーポレイテッド 溶血、凝固調節および細胞外小胞の安定化のための組成物
WO2021112119A1 (ja) * 2019-12-05 2021-06-10 積水メディカル株式会社 血液採取容器及び血漿の分離方法
WO2021182575A1 (ja) * 2020-03-11 2021-09-16 積水メディカル株式会社 白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3006109T3 (pl) 2009-05-15 2019-12-31 Becton, Dickinson And Company Urządzenie do rozdzielania faz gęstości

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01199158A (ja) * 1987-10-20 1989-08-10 Seitetsu Kagaku Co Ltd 赤血球保存液
JP2005501236A (ja) * 2001-08-23 2005-01-13 イムニベスト・コーポレイション 分析用の細胞および生物学的検体の安定化
JP2007271388A (ja) * 2006-03-30 2007-10-18 Hidetoshi Tsuchida 血清または血漿の分離方法および血液分離管
JP2014524027A (ja) * 2011-07-05 2014-09-18 ベクトン・ディキンソン・アンド・カンパニー 凝固制御剤およびそれを含む装置
JP2015506482A (ja) * 2012-02-02 2015-03-02 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 血液安定剤を含んだサンプル採取器具
WO2013168767A1 (ja) * 2012-05-10 2013-11-14 コニカミノルタ株式会社 赤血球除去方法および採血用遠沈管
WO2015046557A1 (ja) * 2013-09-30 2015-04-02 積水メディカル株式会社 循環腫瘍細胞濃縮分離デバイス及び循環腫瘍細胞の濃縮分離方法
JP2020523577A (ja) * 2017-06-13 2020-08-06 スン・チュン・チンＣｈｕｎｇ Ｃｈｉｎ ＳＵＮ 新規な血清タンパク質の活性の保存方法
JP2021500585A (ja) * 2017-10-19 2021-01-07 ストレック， インコーポレイテッド 溶血、凝固調節および細胞外小胞の安定化のための組成物
JP2019211216A (ja) * 2018-05-31 2019-12-12 アークレイ株式会社 血液中の稀少細胞検査、該検査ための血液処理方法及び採血管
WO2021112119A1 (ja) * 2019-12-05 2021-06-10 積水メディカル株式会社 血液採取容器及び血漿の分離方法
WO2021182575A1 (ja) * 2020-03-11 2021-09-16 積水メディカル株式会社 白血球濃縮分離デバイス、血液採取容器及び白血球の分離方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024070504A1 (ja) * 2022-09-29 2024-04-04 積水メディカル株式会社 血液保存用組成物及び血液採取容器

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CN118284808A (zh) 2024-07-02
EP4502599A1 (en) 2025-02-05
KR20240168912A (ko) 2024-12-02
WO2023181468A1 (ja) 2023-09-28
US20250197810A1 (en) 2025-06-19
JPWO2023181468A1 (https=) 2023-09-28

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