JP7335277B2 - 膀胱がんの治療のための方法 - Google Patents

膀胱がんの治療のための方法 Download PDF

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JP7335277B2
JP7335277B2 JP2020566898A JP2020566898A JP7335277B2 JP 7335277 B2 JP7335277 B2 JP 7335277B2 JP 2020566898 A JP2020566898 A JP 2020566898A JP 2020566898 A JP2020566898 A JP 2020566898A JP 7335277 B2 JP7335277 B2 JP 7335277B2
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compound
sting
pharmaceutically acceptable
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acceptable salt
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JP2021525758A (ja
JP2021525758A5 (enExample
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ダエ-シク キム,
フランク ファン,
篤史 遠藤
ヒョン-ウック チョイ,
ミン-ホン ハオ,
シンフェン バオ,
クアン-チュン フアン,
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Eisai R&D Management Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2020566898A 2018-06-01 2019-05-31 膀胱がんの治療のための方法 Active JP7335277B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862679495P 2018-06-01 2018-06-01
US62/679,495 2018-06-01
US201962826347P 2019-03-29 2019-03-29
US62/826,347 2019-03-29
PCT/US2019/034933 WO2019232392A1 (en) 2018-06-01 2019-05-31 Methods for the treatment of bladder cancer

Publications (3)

Publication Number Publication Date
JP2021525758A JP2021525758A (ja) 2021-09-27
JP2021525758A5 JP2021525758A5 (enExample) 2022-06-03
JP7335277B2 true JP7335277B2 (ja) 2023-08-29

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JP2020566898A Active JP7335277B2 (ja) 2018-06-01 2019-05-31 膀胱がんの治療のための方法

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US (1) US12251394B2 (enExample)
EP (1) EP3801561B1 (enExample)
JP (1) JP7335277B2 (enExample)
KR (1) KR102993248B1 (enExample)
CN (1) CN112512531B (enExample)
AU (1) AU2019277679B2 (enExample)
BR (1) BR112020024605A2 (enExample)
CA (1) CA3101623A1 (enExample)
MX (1) MX2020012964A (enExample)
SG (1) SG11202011434SA (enExample)
WO (1) WO2019232392A1 (enExample)

Families Citing this family (2)

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Publication number Priority date Publication date Assignee Title
US20230141284A1 (en) 2020-04-10 2023-05-11 Ono Pharmaceutical Co., Ltd. Cancer therapeutic method
EP4398901A1 (en) 2021-09-09 2024-07-17 Eisai R&D Management Co., Ltd. Biomarkers for sting agonists and methods of using the same

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JP2018522914A (ja) 2015-08-13 2018-08-16 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. Stingアゴニストとしての環状ジヌクレオチド化合物
JP2020508304A (ja) 2017-02-17 2020-03-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 がんの治療のための化合物

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CU24377B1 (es) 2013-05-18 2018-12-05 Aduro Biotech Inc Dinucléotidos de purina cíclicos y composiciones de los mismos útiles para inducir la producción de interferón de tipo i dependientes de sting
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JP2016538344A (ja) * 2013-11-19 2016-12-08 ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago 癌処置としてのstingアゴニストの使用
EP3071229A4 (en) 2013-11-22 2017-05-10 Brock University Use of fluorinated cyclic dinucleotides as oral vaccine adjuvants
EP3152217B1 (en) 2014-06-04 2018-08-01 GlaxoSmithKline Intellectual Property Development Limited Cyclic di-nucleotides as modulators of sting
DK3233882T3 (da) 2014-12-16 2020-01-27 Kayla Therapeutics Fluorinerede cykliske dinukleotider til cytokininduktion
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TWI706958B (zh) 2015-03-10 2020-10-11 美商艾杜諾生物科技公司 活化「干擾素基因刺激因子」依賴性訊息傳導之組合物及方法
KR20180066241A (ko) 2015-10-28 2018-06-18 아두로 바이오테크, 인코포레이티드 “인터페론 유전자의 자극제”-의존성 신호전달을 활성화시키기 위한 조성물 및 방법
JP6411676B2 (ja) 2015-12-03 2018-10-24 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Stingの調節因子としての環状プリンジヌクレオチド
WO2017123657A1 (en) 2016-01-11 2017-07-20 Gary Glick Cyclic dinucleotides for treating conditions associated with sting activity such as cancer
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TWI808092B (zh) 2017-08-30 2023-07-11 中國大陸商北京軒義醫藥科技有限公司 作為干擾素基因調節劑之刺激劑的環狀二核苷酸
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Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
JP2018507192A (ja) 2015-01-29 2018-03-15 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 特に癌の治療に有用な環状ヌクレオチド
JP2018522914A (ja) 2015-08-13 2018-08-16 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. Stingアゴニストとしての環状ジヌクレオチド化合物
JP2020508304A (ja) 2017-02-17 2020-03-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 がんの治療のための化合物

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JP2021525758A (ja) 2021-09-27
US20210205348A1 (en) 2021-07-08
EP3801561B1 (en) 2025-03-19
CA3101623A1 (en) 2019-12-05
CN112512531B (zh) 2024-04-09
CN112512531A (zh) 2021-03-16
WO2019232392A1 (en) 2019-12-05
MX2020012964A (es) 2021-02-16
BR112020024605A2 (pt) 2021-04-06
SG11202011434SA (en) 2020-12-30
AU2019277679B2 (en) 2024-11-28
EP3801561A1 (en) 2021-04-14
US12251394B2 (en) 2025-03-18
AU2019277679A1 (en) 2020-12-24
KR20210015937A (ko) 2021-02-10
KR102993248B1 (ko) 2026-07-21

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