JP7319020B2 - がんの治療での使用のためのccr5阻害剤 - Google Patents

がんの治療での使用のためのccr5阻害剤 Download PDF

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JP7319020B2
JP7319020B2 JP2020567109A JP2020567109A JP7319020B2 JP 7319020 B2 JP7319020 B2 JP 7319020B2 JP 2020567109 A JP2020567109 A JP 2020567109A JP 2020567109 A JP2020567109 A JP 2020567109A JP 7319020 B2 JP7319020 B2 JP 7319020B2
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cancer
ccr5
seq
administered
terminal portion
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JP2021525770A5 (enExample
JP2021525770A (ja
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オリバー ハートレー,
ロビン エワート オフォード,
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Orion Biotechnology Switzerland SARL
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2020567109A 2018-05-28 2019-05-24 がんの治療での使用のためのccr5阻害剤 Active JP7319020B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023116746A JP2023134704A (ja) 2018-05-28 2023-07-18 がんの治療での使用のためのccr5阻害剤

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862677114P 2018-05-28 2018-05-28
US62/677,114 2018-05-28
US201962792600P 2019-01-15 2019-01-15
US62/792,600 2019-01-15
PCT/IB2019/054350 WO2019229616A1 (en) 2018-05-28 2019-05-24 Ccr5 inhibitor for use in treating cancer

Related Child Applications (1)

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JP2023116746A Division JP2023134704A (ja) 2018-05-28 2023-07-18 がんの治療での使用のためのccr5阻害剤

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JP2021525770A JP2021525770A (ja) 2021-09-27
JP2021525770A5 JP2021525770A5 (enExample) 2022-05-23
JP7319020B2 true JP7319020B2 (ja) 2023-08-01

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JP2020567109A Active JP7319020B2 (ja) 2018-05-28 2019-05-24 がんの治療での使用のためのccr5阻害剤
JP2023116746A Pending JP2023134704A (ja) 2018-05-28 2023-07-18 がんの治療での使用のためのccr5阻害剤

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US (1) US20210205411A1 (enExample)
EP (1) EP3813870B1 (enExample)
JP (2) JP7319020B2 (enExample)
KR (1) KR20210016398A (enExample)
CN (1) CN112469429B (enExample)
AU (1) AU2019276939A1 (enExample)
BR (1) BR112020024328A2 (enExample)
CA (1) CA3101556A1 (enExample)
MX (1) MX2020012782A (enExample)
WO (1) WO2019229616A1 (enExample)
ZA (1) ZA202007955B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114729023A (zh) * 2019-04-01 2022-07-08 西托戴恩股份有限公司 阻断癌症转移或增强由dna损伤化学疗法诱导的细胞死亡的抗ccr5药剂和治疗方法
WO2021231648A2 (en) * 2020-05-12 2021-11-18 Gigagen, Inc. Cancer therapeutics comprising chemokine or its analog
WO2024146707A1 (en) * 2023-01-06 2024-07-11 Université De Genève Variant ligand conjugates for payload delivery
WO2025172252A1 (en) 2024-02-15 2025-08-21 Novo Nordisk A/S Protracted ccr5 antagonists and uses thereof
WO2025176787A1 (en) * 2024-02-22 2025-08-28 Orion Biotechnology Holding Sa Ccl5 variants for modulating gpr75

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009544304A (ja) 2006-07-25 2009-12-17 ミンタカ ファンデーション フォア メディカル リサーチ サイトカイン誘導体
JP2017535534A (ja) 2014-10-27 2017-11-30 ルプレヒト−カールス−ウニヴェルジテート ハイデルベルクRuprecht−Karls−Universitaet Heidelberg がんを治療するための単独または併用療法におけるccr5拮抗剤の使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201109438A (en) * 2009-07-29 2011-03-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
US8916696B2 (en) * 2011-06-12 2014-12-23 City Of Hope Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
EP3693041A1 (en) * 2011-06-13 2020-08-12 TLA Targeted Immunotherapies AB Treating cancer
HK1209673A1 (en) * 2012-05-14 2016-04-08 Prostagene Llc Using modulators of ccr5 for treating cancer
US20150250837A1 (en) * 2012-09-20 2015-09-10 Morningside Technology Ventures Ltd. Oncolytic virus encoding pd-1 binding agents and uses of the same
AR105654A1 (es) * 2015-08-24 2017-10-25 Lilly Co Eli Anticuerpos pd-l1 (ligando 1 de muerte celular programada)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009544304A (ja) 2006-07-25 2009-12-17 ミンタカ ファンデーション フォア メディカル リサーチ サイトカイン誘導体
JP2017535534A (ja) 2014-10-27 2017-11-30 ルプレヒト−カールス−ウニヴェルジテート ハイデルベルクRuprecht−Karls−Universitaet Heidelberg がんを治療するための単独または併用療法におけるccr5拮抗剤の使用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Oncotarget,2016年06月22日,Vol.7, No.30,p.48335-48345

Also Published As

Publication number Publication date
AU2019276939A1 (en) 2021-01-21
EP3813870B1 (en) 2023-11-15
US20210205411A1 (en) 2021-07-08
MX2020012782A (es) 2021-04-28
CA3101556A1 (en) 2019-12-05
BR112020024328A2 (pt) 2021-02-23
JP2021525770A (ja) 2021-09-27
EP3813870C0 (en) 2023-11-15
ZA202007955B (en) 2022-06-29
CN112469429B (zh) 2025-02-14
KR20210016398A (ko) 2021-02-15
EP3813870A1 (en) 2021-05-05
JP2023134704A (ja) 2023-09-27
CN112469429A (zh) 2021-03-09
WO2019229616A1 (en) 2019-12-05

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