JP7295559B2 - キトサン系複合体組成物及びキトサン系複合体の製造方法 - Google Patents
キトサン系複合体組成物及びキトサン系複合体の製造方法 Download PDFInfo
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- JP7295559B2 JP7295559B2 JP2019104022A JP2019104022A JP7295559B2 JP 7295559 B2 JP7295559 B2 JP 7295559B2 JP 2019104022 A JP2019104022 A JP 2019104022A JP 2019104022 A JP2019104022 A JP 2019104022A JP 7295559 B2 JP7295559 B2 JP 7295559B2
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- chitosan
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- film
- based composite
- chitin
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- 229920001661 Chitosan Polymers 0.000 title claims description 83
- 239000002131 composite material Substances 0.000 title claims description 43
- 238000004519 manufacturing process Methods 0.000 title claims description 27
- 239000000203 mixture Substances 0.000 title claims description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 27
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims description 22
- 229920000642 polymer Polymers 0.000 claims description 19
- 239000002904 solvent Substances 0.000 claims description 17
- 150000004676 glycans Chemical class 0.000 claims description 14
- 229920001282 polysaccharide Polymers 0.000 claims description 14
- 239000005017 polysaccharide Substances 0.000 claims description 14
- 238000010438 heat treatment Methods 0.000 claims description 11
- 229920001577 copolymer Polymers 0.000 claims description 9
- 239000000725 suspension Substances 0.000 claims description 8
- -1 5-methyl-5-benzyloxybenzylcarbonyl-1,3-dioxan-2-one Chemical compound 0.000 claims description 4
- FPXMWTIQAUOFBN-UHFFFAOYSA-N benzyl 5-methyl-2-oxo-1,3-dioxane-5-carboxylate Chemical compound C=1C=CC=CC=1COC(=O)C1(C)COC(=O)OC1 FPXMWTIQAUOFBN-UHFFFAOYSA-N 0.000 claims description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- 239000002798 polar solvent Substances 0.000 claims 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 claims 1
- 239000000243 solution Substances 0.000 description 61
- 229920002101 Chitin Polymers 0.000 description 36
- 238000000034 method Methods 0.000 description 30
- 229920000166 polytrimethylene carbonate Polymers 0.000 description 23
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 14
- 238000010586 diagram Methods 0.000 description 13
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 12
- 238000005033 Fourier transform infrared spectroscopy Methods 0.000 description 10
- 239000004809 Teflon Substances 0.000 description 10
- 229920006362 Teflon® Polymers 0.000 description 10
- 238000001228 spectrum Methods 0.000 description 10
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 description 9
- 238000009864 tensile test Methods 0.000 description 8
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 230000000704 physical effect Effects 0.000 description 6
- 238000005160 1H NMR spectroscopy Methods 0.000 description 4
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 4
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000012567 medical material Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 238000001157 Fourier transform infrared spectrum Methods 0.000 description 3
- 239000011259 mixed solution Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000012669 compression test Methods 0.000 description 2
- 239000013067 intermediate product Substances 0.000 description 2
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 description 2
- 230000037361 pathway Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 2
- 241000238424 Crustacea Species 0.000 description 1
- 241000238557 Decapoda Species 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- OKJPEAGHQZHRQV-UHFFFAOYSA-N Triiodomethane Natural products IC(I)I OKJPEAGHQZHRQV-UHFFFAOYSA-N 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 238000005576 amination reaction Methods 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- WHQSYGRFZMUQGQ-UHFFFAOYSA-N n,n-dimethylformamide;hydrate Chemical compound O.CN(C)C=O WHQSYGRFZMUQGQ-UHFFFAOYSA-N 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- PUVAFTRIIUSGLK-UHFFFAOYSA-M trimethyl(oxiran-2-ylmethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CC1CO1 PUVAFTRIIUSGLK-UHFFFAOYSA-M 0.000 description 1
Images
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- Manufacture Of Macromolecular Shaped Articles (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polyesters Or Polycarbonates (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019104022A JP7295559B2 (ja) | 2019-06-03 | 2019-06-03 | キトサン系複合体組成物及びキトサン系複合体の製造方法 |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019104022A JP7295559B2 (ja) | 2019-06-03 | 2019-06-03 | キトサン系複合体組成物及びキトサン系複合体の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020196823A JP2020196823A (ja) | 2020-12-10 |
| JP2020196823A5 JP2020196823A5 (https=) | 2022-05-23 |
| JP7295559B2 true JP7295559B2 (ja) | 2023-06-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019104022A Active JP7295559B2 (ja) | 2019-06-03 | 2019-06-03 | キトサン系複合体組成物及びキトサン系複合体の製造方法 |
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| Country | Link |
|---|---|
| JP (1) | JP7295559B2 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7741549B2 (ja) * | 2022-01-06 | 2025-09-18 | 国立大学法人 奈良先端科学技術大学院大学 | 管腔内留置用医療デバイスのコーティング材 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000290303A (ja) | 1999-04-08 | 2000-10-17 | Tsuyakku Kk | 脱アセチル化キチン誘導体及びその合成方法 |
| JP2007301213A (ja) | 2006-05-12 | 2007-11-22 | Nipro Corp | 被覆ステントおよびその製造方法 |
| JP2012522098A (ja) | 2009-03-31 | 2012-09-20 | アルケマ フランス | （バイオ）−ポリカーボネートを得るための環状カーボネートの開環重合用有機系 |
| JP2016116873A (ja) | 2016-01-20 | 2016-06-30 | 東タイ株式会社 | 生体吸収性縫合糸 |
| WO2017204276A1 (ja) | 2016-05-26 | 2017-11-30 | 株式会社ダイセル | カルボキシル基含有ポリカーボネートポリオール |
| WO2017216609A1 (en) | 2016-06-15 | 2017-12-21 | Tubitak | Multifunctional hernia patch |
| WO2018219987A1 (en) | 2017-05-30 | 2018-12-06 | Aqpha Ip B.V. | Resorbable biodegradable medical and cosmetic composition comprising poly(1,3-trimethylene carbonate) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4142186A1 (de) * | 1991-12-20 | 1993-06-24 | Bayer Ag | Verfahren zum verschaeumen von thermoplastischen polycarbonaten |
| JP3483753B2 (ja) * | 1997-12-29 | 2004-01-06 | タキロン株式会社 | 生体内分解吸収性可塑性粘着物 |
| JPH11247067A (ja) * | 1998-02-27 | 1999-09-14 | Fuji Spinning Co Ltd | ポリエステル系合成繊維製品の親水化加工方法 |
| BRPI0910198A2 (pt) * | 2008-06-30 | 2016-01-12 | Silenseed Ltd | composição para administração a partir de um sítio local de um agente baseado em nucleotídeos e método para tratar um sujeito sofrendo de uma doença requerendo tratamento local com um agente baseado em nucleotídeo. |
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- 2019-06-03 JP JP2019104022A patent/JP7295559B2/ja active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000290303A (ja) | 1999-04-08 | 2000-10-17 | Tsuyakku Kk | 脱アセチル化キチン誘導体及びその合成方法 |
| JP2007301213A (ja) | 2006-05-12 | 2007-11-22 | Nipro Corp | 被覆ステントおよびその製造方法 |
| JP2012522098A (ja) | 2009-03-31 | 2012-09-20 | アルケマ フランス | （バイオ）−ポリカーボネートを得るための環状カーボネートの開環重合用有機系 |
| JP2016116873A (ja) | 2016-01-20 | 2016-06-30 | 東タイ株式会社 | 生体吸収性縫合糸 |
| WO2017204276A1 (ja) | 2016-05-26 | 2017-11-30 | 株式会社ダイセル | カルボキシル基含有ポリカーボネートポリオール |
| WO2017216609A1 (en) | 2016-06-15 | 2017-12-21 | Tubitak | Multifunctional hernia patch |
| JP2019517892A (ja) | 2016-06-15 | 2019-06-27 | チュビタック （ターキー ビリムセル ヴィ テクノロジク アラスティルマ クルム）Ｔｕｂｉｔａｋ （Ｔｕｒｋｉｙｅ Ｂｉｌｉｍｓｅｌ Ｖｅ Ｔｅｋｎｏｌｏｊｉｋ Ａｒａｓｔｉｒｍａ Ｋｕｒｕｍｕ） | 多機能ヘルニアパッチ |
| WO2018219987A1 (en) | 2017-05-30 | 2018-12-06 | Aqpha Ip B.V. | Resorbable biodegradable medical and cosmetic composition comprising poly(1,3-trimethylene carbonate) |
| JP2020521803A (ja) | 2017-05-30 | 2020-07-27 | アクファー アイピー ビー．ヴィー．Ａｑｐｈａ Ｉｐ Ｂ．Ｖ． | ポリ（１，３−トリメチレンカーボネート）を含む再吸収性の生分解性医療用及び化粧品組成物 |
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| Publication number | Publication date |
|---|---|
| JP2020196823A (ja) | 2020-12-10 |
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