JP7295030B2 - グリピカン３を特異的に認識するコンストラクト及びその使用 - Google Patents

グリピカン３を特異的に認識するコンストラクト及びその使用 Download PDF

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JP7295030B2
JP7295030B2 JP2019558615A JP2019558615A JP7295030B2 JP 7295030 B2 JP7295030 B2 JP 7295030B2 JP 2019558615 A JP2019558615 A JP 2019558615A JP 2019558615 A JP2019558615 A JP 2019558615A JP 7295030 B2 JP7295030 B2 JP 7295030B2
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amino acid
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acid sequence
gpc3
cdr2
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JP2020517294A (ja
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ペンボー ジャン，
イーヤン シュー，
ハビエル モラレス，
陽子 中野
ホン リュー，
ジンイー シャン，
ティモシー アッカー，
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ユーリカ セラピューティックス， インコーポレイテッド
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    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/00118—Cancer antigens from embryonic or fetal origin
    • A61K39/001181—Alpha-feto protein
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    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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JP2019558615A 2017-04-26 2018-04-24 グリピカン３を特異的に認識するコンストラクト及びその使用 Active JP7295030B2 (ja)

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JP2023094432A JP2023123540A (ja) 2017-04-26 2023-06-07 グリピカン３を特異的に認識するコンストラクト及びその使用

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US201762490586P 2017-04-26 2017-04-26
US62/490,586 2017-04-26
PCT/US2018/029221 WO2018200586A1 (en) 2017-04-26 2018-04-24 Constructs specifically recognizing glypican 3 and uses thereof

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JP2020517294A JP2020517294A (ja) 2020-06-18
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US (2) US11447564B2 (https=)
EP (1) EP3615574A4 (https=)
JP (2) JP7295030B2 (https=)
KR (2) KR102663596B1 (https=)
CN (1) CN110741019B (https=)
AU (1) AU2018258049B2 (https=)
CA (1) CA3059820A1 (https=)
IL (2) IL319308A (https=)
MX (2) MX420947B (https=)
MY (1) MY201065A (https=)
PH (1) PH12019502412A1 (https=)
SG (2) SG11201909728XA (https=)
TW (1) TWI878207B (https=)
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EP3615574A4 (en) 2017-04-26 2021-02-24 Eureka Therapeutics, Inc. SPECIFIC GLYPICAN 3 RECOGNIZING CONSTRUCTS AND THEIR USE
JP7538601B2 (ja) 2017-04-26 2024-08-22 ユーリカ セラピューティックス， インコーポレイテッド キメラ活性化受容体及びキメラ刺激受容体を発現する細胞並びにその使用
CA3102641A1 (en) 2018-06-22 2019-12-26 Kite Pharma, Inc. Chimeric transmembrane proteins and uses thereof
SG11202103234RA (en) * 2018-10-01 2021-04-29 Adicet Bio Inc COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON-ENGINEERED γδ -T CELLS FOR TREATMENT OF SOLID TUMORS
US10815308B2 (en) * 2018-12-21 2020-10-27 Kymab Limited FIXaxFX bispecific antibody with common light chain
CN113490689B (zh) * 2019-02-01 2024-06-04 恺兴生命科技(上海)有限公司 Tcr融合蛋白及表达tcr融合蛋白的细胞
EP3965897A4 (en) * 2019-05-07 2023-01-04 The Board of Trustees of the Leland Stanford Junior University CHEMERA ANTIGEN RECEPTORS TARGETING GLYPICAN-2
CN114391021B (zh) 2019-06-21 2026-01-16 凯德药业股份有限公司 TGF-β受体和使用方法
WO2021105989A1 (en) * 2019-11-26 2021-06-03 Ramot At Tel-Aviv University Ltd. Chimeric antigen receptor to carbohydrate antigens
WO2021126672A1 (en) * 2019-12-20 2021-06-24 Medimmune, Llc Compositions and methods of treating cancer with chimeric antigen receptors targeting glypican 3
MX2022009827A (es) * 2020-02-14 2022-09-05 Univ Leland Stanford Junior Receptores de antigenos quimericos con activacion de cd2.
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WO2021186395A1 (en) * 2020-03-18 2021-09-23 Eutilex Co., Ltd. Gpc3 car- t cells secreting il-18 and methods of making and using the same
MX2022013920A (es) * 2020-05-07 2022-11-30 Phanes Therapeutics Inc Anticuerpos anti-antigeno asociado con tumor y usos de los mismos.
TW202216788A (zh) * 2020-06-26 2022-05-01 日商協和麒麟股份有限公司 與GPC3及TfR結合之雙特異性抗體
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