JP7278961B2 - T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法 - Google Patents

T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法 Download PDF

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JP7278961B2
JP7278961B2 JP2019553220A JP2019553220A JP7278961B2 JP 7278961 B2 JP7278961 B2 JP 7278961B2 JP 2019553220 A JP2019553220 A JP 2019553220A JP 2019553220 A JP2019553220 A JP 2019553220A JP 7278961 B2 JP7278961 B2 JP 7278961B2
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cells
car
dasatinib
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ponatinib
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JP2020515581A (ja
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リン,レイチェル
マッコール,クリスタル
ウェバー,エヴァン
マロ―トラー,サンジェイ
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Leland Stanford Junior University
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JP2019553220A 2017-03-31 2018-03-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法 Active JP7278961B2 (ja)

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JP2023011257A JP2023055805A (ja) 2017-03-31 2023-01-27 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024123405A JP2024153812A (ja) 2017-03-31 2024-07-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法

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US201762479930P 2017-03-31 2017-03-31
US62/479,930 2017-03-31
PCT/US2018/025394 WO2018183842A1 (en) 2017-03-31 2018-03-30 Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling

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JP2020515581A5 JP2020515581A5 (cg-RX-API-DMAC7.html) 2021-05-06
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JP2019553220A Active JP7278961B2 (ja) 2017-03-31 2018-03-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2019553214A Active JP7249287B2 (ja) 2017-03-31 2018-03-30 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法
JP2022193805A Active JP7674328B2 (ja) 2017-03-31 2022-12-02 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法
JP2023011257A Pending JP2023055805A (ja) 2017-03-31 2023-01-27 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024123405A Pending JP2024153812A (ja) 2017-03-31 2024-07-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024200383A Pending JP2025026930A (ja) 2017-03-31 2024-11-18 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法

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JP2022193805A Active JP7674328B2 (ja) 2017-03-31 2022-12-02 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法
JP2023011257A Pending JP2023055805A (ja) 2017-03-31 2023-01-27 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024123405A Pending JP2024153812A (ja) 2017-03-31 2024-07-30 T細胞受容体のシグナル伝達を阻害するまたは調節することによってt細胞の疲弊を治療する方法
JP2024200383A Pending JP2025026930A (ja) 2017-03-31 2024-11-18 T細胞受容体シグナル伝達を阻害または調節することによって、t細胞枯渇を処置する方法

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CN111699001A (zh) * 2017-12-07 2020-09-22 尤利乌斯·马克西米利安维尔茨堡大学 达沙替尼和其他酪氨酸激酶抑制剂对基因修饰的嵌合抗原受体t细胞的功能的控制和调节
US20210393628A1 (en) * 2018-10-30 2021-12-23 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for modulating t cell exhaustion
EP3876958A1 (en) * 2018-11-08 2021-09-15 Juno Therapeutics, Inc. Methods and combinations for treatment and t cell modulation
AU2020231810B2 (en) * 2019-03-01 2025-12-18 National University Of Singapore Engineered immune cells
CN110157680A (zh) * 2019-05-08 2019-08-23 浙江大学 提高嵌合抗原受体t细胞疗效和作用持久性的细胞培养方法
WO2021020564A1 (ja) * 2019-08-01 2021-02-04 国立大学法人三重大学 Gd2結合性分子
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