JP7161940B2 - がんの治療のための、補体不活性化に耐性のエンベロープウイルス - Google Patents

がんの治療のための、補体不活性化に耐性のエンベロープウイルス Download PDF

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JP7161940B2
JP7161940B2 JP2018564966A JP2018564966A JP7161940B2 JP 7161940 B2 JP7161940 B2 JP 7161940B2 JP 2018564966 A JP2018564966 A JP 2018564966A JP 2018564966 A JP2018564966 A JP 2018564966A JP 7161940 B2 JP7161940 B2 JP 7161940B2
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sequence
virus
fusion protein
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nucleic acid
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ティアンチ ルオ
ルネ モリーナ
ガブリエル カスティーユ
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Wellstat ImmunoTherapeutics LLC
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • C—CHEMISTRY; METALLURGY
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
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    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18151—Methods of production or purification of viral material
    • C12N2760/18152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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JP2018564966A 2017-05-10 2018-05-10 がんの治療のための、補体不活性化に耐性のエンベロープウイルス Active JP7161940B2 (ja)

Applications Claiming Priority (3)

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US201762504120P 2017-05-10 2017-05-10
US62/504,120 2017-05-10
PCT/US2018/032018 WO2018209052A1 (en) 2017-05-10 2018-05-10 Enveloped virus resistant to complement inactivation for the treatment of cancer

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JP2020519230A JP2020519230A (ja) 2020-07-02
JP2020519230A5 JP2020519230A5 (cg-RX-API-DMAC10.html) 2021-05-20
JP7161940B2 true JP7161940B2 (ja) 2022-10-27

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US (2) US11274141B2 (cg-RX-API-DMAC10.html)
EP (1) EP3621635A4 (cg-RX-API-DMAC10.html)
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KR (3) KR102839445B1 (cg-RX-API-DMAC10.html)
CN (3) CN121343934A (cg-RX-API-DMAC10.html)
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CA (1) CA3026892A1 (cg-RX-API-DMAC10.html)
IL (1) IL263979B2 (cg-RX-API-DMAC10.html)
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BR112019018915A2 (pt) 2017-03-15 2020-04-14 Pandion Therapeutics Inc imunotolerância direcionada
AU2018273914A1 (en) 2017-05-24 2019-11-14 Pandion Operations, Inc. Targeted immunotolerance
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
USRE50550E1 (en) 2017-12-06 2025-08-26 Pandion Operations, Inc. IL-2 muteins and uses thereof
US10174091B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
CN112759654A (zh) * 2019-11-06 2021-05-07 深圳普菲科生命科技有限公司 一种病毒囊膜蛋白装配系统及其方法和应用
US11981715B2 (en) 2020-02-21 2024-05-14 Pandion Operations, Inc. Tissue targeted immunotolerance with a CD39 effector
EP4299729A4 (en) * 2021-02-26 2025-06-11 SillaJen, Inc. ONCOLYTIC VIRUS AND USE THEREOF
CN113736810B (zh) * 2021-09-08 2024-05-24 苏州因特药物研发有限公司 构建体、载体、蛋白、细胞、制备方法、产品及应用
KR102983542B1 (ko) * 2022-06-29 2026-06-30 신라젠(주) Cd55 및 cd59를 동시 발현하는 항암 바이러스
KR20240035360A (ko) * 2022-09-07 2024-03-15 신라젠(주) 항암 바이러스의 신규 용도

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JP2008507272A (ja) 2004-07-21 2008-03-13 ダナ−ファーバー キャンサー インスティチュート,インコーポレイテッド レンチウイルスベクターおよびその使用
JP2008061539A (ja) 2006-09-05 2008-03-21 Osaka Univ ヒト補体制御因子発現遺伝子およびその利用
WO2016174407A1 (en) 2015-04-27 2016-11-03 Ucl Business Plc Nucleic acid construct for expressing more than one chimeric antigen receptor

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NZ748798A (en) 2026-03-27
CN121343935A (zh) 2026-01-16
ZA201808040B (en) 2019-09-25
CN109414483A (zh) 2019-03-01
US11274141B2 (en) 2022-03-15
WO2018209052A1 (en) 2018-11-15
CN121343934A (zh) 2026-01-16
JP2020519230A (ja) 2020-07-02
EP3621635A4 (en) 2021-02-24
US20190194292A1 (en) 2019-06-27
KR20250118857A (ko) 2025-08-06
AU2018265258B2 (en) 2023-01-05
BR112018075281A2 (pt) 2020-02-11
IL263979B2 (en) 2023-09-01
IL263979A (en) 2019-02-28
RU2018146446A3 (cg-RX-API-DMAC10.html) 2021-09-10
KR20200005721A (ko) 2020-01-16
RU2018146446A (ru) 2021-06-10
IL263979B1 (en) 2023-05-01
KR20240073085A (ko) 2024-05-24
MX2018015599A (es) 2019-05-16
EP3621635A1 (en) 2020-03-18
KR102839445B1 (ko) 2025-07-28
US20220169701A1 (en) 2022-06-02
AU2018265258A1 (en) 2019-01-17
CN109414483B (zh) 2025-10-24
CA3026892A1 (en) 2018-11-15
KR102662049B1 (ko) 2024-05-23

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