JP7148605B2 - 医学療法におけるセマグルチド - Google Patents

医学療法におけるセマグルチド Download PDF

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Publication number
JP7148605B2
JP7148605B2 JP2020517328A JP2020517328A JP7148605B2 JP 7148605 B2 JP7148605 B2 JP 7148605B2 JP 2020517328 A JP2020517328 A JP 2020517328A JP 2020517328 A JP2020517328 A JP 2020517328A JP 7148605 B2 JP7148605 B2 JP 7148605B2
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Japan
Prior art keywords
semaglutide
medicament
subject
administered
weight
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JP2020517328A
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English (en)
Japanese (ja)
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JP2020536854A5 (enExample
JP2020536854A (ja
Inventor
カビッシュ、マリア
ハンセン、トーマス
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Novo Nordisk AS
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Novo Nordisk AS
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60083831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP7148605(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of JP2020536854A publication Critical patent/JP2020536854A/ja
Publication of JP2020536854A5 publication Critical patent/JP2020536854A5/ja
Priority to JP2022112446A priority Critical patent/JP7475398B2/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2020517328A 2017-10-12 2018-10-10 医学療法におけるセマグルチド Active JP7148605B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022112446A JP7475398B2 (ja) 2017-10-12 2022-07-13 医学療法におけるセマグルチド

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17196254 2017-10-12
EP17196254.1 2017-10-12
PCT/EP2018/077654 WO2019072941A1 (en) 2017-10-12 2018-10-10 SEMAGLUTIDE IN MEDICAL THERAPY

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022112446A Division JP7475398B2 (ja) 2017-10-12 2022-07-13 医学療法におけるセマグルチド

Publications (3)

Publication Number Publication Date
JP2020536854A JP2020536854A (ja) 2020-12-17
JP2020536854A5 JP2020536854A5 (enExample) 2021-07-29
JP7148605B2 true JP7148605B2 (ja) 2022-10-05

Family

ID=60083831

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020517328A Active JP7148605B2 (ja) 2017-10-12 2018-10-10 医学療法におけるセマグルチド
JP2022112446A Active JP7475398B2 (ja) 2017-10-12 2022-07-13 医学療法におけるセマグルチド

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022112446A Active JP7475398B2 (ja) 2017-10-12 2022-07-13 医学療法におけるセマグルチド

Country Status (18)

Country Link
US (4) US12029779B2 (enExample)
EP (1) EP3694538A1 (enExample)
JP (2) JP7148605B2 (enExample)
KR (1) KR20200069316A (enExample)
CN (4) CN119838000A (enExample)
AU (2) AU2018348929B2 (enExample)
BR (1) BR112020006246A2 (enExample)
CA (1) CA3078652A1 (enExample)
CL (1) CL2020000812A1 (enExample)
IL (3) IL322968A (enExample)
MA (1) MA50358A (enExample)
MX (3) MX2020003049A (enExample)
MY (1) MY204827A (enExample)
PH (1) PH12020550185A1 (enExample)
SG (1) SG11202002841PA (enExample)
TW (1) TWI842681B (enExample)
WO (1) WO2019072941A1 (enExample)
ZA (3) ZA202503387B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL322968A (en) * 2017-10-12 2025-10-01 Novo Nordisk As Semaglutide in medical treatment
MX2022009844A (es) * 2020-02-18 2022-09-05 Novo Nordisk As Composiciones y usos del peptido similar al glucagon-1 (glp-1).
US11478533B2 (en) * 2020-04-27 2022-10-25 Novo Nordisk A/S Semaglutide for use in medicine
WO2022212268A1 (en) * 2021-03-29 2022-10-06 Sanford Health Methods and compositions for treating lysosomal storage disorders
AU2023285400A1 (en) * 2022-06-08 2024-12-05 Zydus Lifesciences Limited Reusable multi-dose, variable dose, single pen injector for type 2 diabetes and weight management
WO2024249659A2 (en) * 2023-05-30 2024-12-05 The Medical College Of Wisconsin, Inc. Methods for weight loss and/or reducing weight gain
US20240404673A1 (en) * 2023-06-05 2024-12-05 Closed Loop Medicine Ltd. Dosing of incretin pathway drugs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015522573A (ja) 2012-07-01 2015-08-06 ノヴォ ノルディスク アー／エス 長時間作用型ｇｌｐ−１ペプチドの使用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268343B1 (en) 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
JP5562510B2 (ja) 2001-06-28 2014-07-30 ノヴォ ノルディスク アー／エス 修飾ｇｌｐ−１の安定な処方剤
JP4949838B2 (ja) 2003-09-19 2012-06-13 ノヴォ ノルディスク アー／エス 新規ｇｌｐ−１誘導体
PL3300721T5 (pl) 2003-11-20 2025-11-17 Novo Nordisk A/S Preparaty peptydowe zawierające glikol propylenowy, które są optymalne do produkcji i do zastosowania w urządzeniu do wstrzykiwania
ES2735533T3 (es) 2004-11-12 2019-12-19 Novo Nordisk As Formulaciones estables de GLP-1
TWI372629B (en) 2005-03-18 2012-09-21 Novo Nordisk As Acylated glp-1 compounds
KR101486829B1 (ko) 2005-09-14 2015-01-29 맨카인드 코포레이션 결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법
BRPI0709964A2 (pt) 2006-04-14 2011-08-02 Mannkind Corp formulações farmacêuticas contendo peptìdeo glucagon do tipo 1 (glp-1)
WO2008116088A1 (en) 2007-03-20 2008-09-25 Nippon Kayaku Kabushiki Kaisha Method to monitor drug efficacy in diabetic patients using an assay for 1,5-anhydro-d-glucitol
WO2009030774A1 (en) 2007-09-05 2009-03-12 Novo Nordisk A/S Truncated glp-1 derivatives and their therapeutical use
SI2373681T1 (sl) 2008-12-10 2017-05-31 Glaxosmithkline Llc Corporation Service Company Farmacevtski sestavki albiglutida
EA029759B1 (ru) 2009-02-13 2018-05-31 Бёрингер Ингельхайм Интернациональ Гмбх Антидиабетические лекарственные средства, содержащие ингибитор dpp-4 (линаглиптин) необязательно в комбинации с другими антидиабетическими средствами
HUE027229T2 (en) 2009-12-16 2016-08-29 Novo Nordisk As Double acylated glp-1 derivatives
AU2011249722B2 (en) 2010-05-05 2015-09-17 Boehringer Ingelheim International Gmbh Combination therapy
WO2012016419A1 (zh) 2010-08-06 2012-02-09 浙江贝达药业有限公司 Glp-1衍生物及其应用
HRP20180425T1 (hr) 2010-12-16 2018-04-20 Novo Nordisk A/S Čvrste kompozicije koje sadrže agonist glp-1 i sol n-(8-(2-hidroksibenzoil)amino)kaprilne kiseline
US8975223B2 (en) 2010-12-22 2015-03-10 Marcadia Biotech, Inc. Methods for treating metabolic disorders and obesity with a peptide comprising the amino acid sequence of SEQ ID No. 146
US20130035281A1 (en) 2011-02-09 2013-02-07 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
CN102718858B (zh) 2011-03-29 2014-07-02 天津药物研究院 胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用
WO2012136790A1 (en) 2011-04-07 2012-10-11 Glaxo Group Limited Compositions comprising fusion proteins or conjugates with an improved half -life
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
CN102229668A (zh) 2011-06-03 2011-11-02 浙江贝达药业有限公司 一种glp-1衍生物及其应用
WO2012177929A2 (en) 2011-06-24 2012-12-27 Amylin Pharmaceuticals, Inc. Methods for treating diabetes with extended release formulations of glp-1 receptor agonists
JP6250034B2 (ja) * 2012-05-08 2017-12-20 ノヴォ ノルディスク アー／エス 二重アシル化されたｇｌｐ−１誘導体
ES2688462T3 (es) * 2013-05-02 2018-11-02 Novo Nordisk A/S Dosificación oral de compuestos de GLP-1
CN109715662B (zh) 2015-12-23 2023-07-21 美国安进公司 使用gipr结合蛋白与glp-1激动剂的组合来治疗或改善代谢病症的方法
KR20200047557A (ko) 2017-08-04 2020-05-07 오비드 테라퓨틱스 인크. 당뇨병 및 관련 질환들의 치료에서 가복사돌의 사용
IL322968A (en) * 2017-10-12 2025-10-01 Novo Nordisk As Semaglutide in medical treatment

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015522573A (ja) 2012-07-01 2015-08-06 ノヴォ ノルディスク アー／エス 長時間作用型ｇｌｐ−１ペプチドの使用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ＮＣＴ０２４５３７１１，ＣｌｏｎｉｃａｌＴｒｉａｌｓ．ｇｏｖ ａｒｃｈｉｖｅ，２０１７年７月

Also Published As

Publication number Publication date
IL322968A (en) 2025-10-01
CN119950682A (zh) 2025-05-09
SG11202002841PA (en) 2020-04-29
MY204827A (en) 2024-09-18
MA50358A (fr) 2020-08-19
JP2022132414A (ja) 2022-09-08
RU2020114960A (ru) 2021-10-28
CN111212657A (zh) 2020-05-29
KR20200069316A (ko) 2020-06-16
US12295988B2 (en) 2025-05-13
RU2020114960A3 (enExample) 2022-02-11
IL322969A (en) 2025-10-01
US20200237876A1 (en) 2020-07-30
US20240415935A1 (en) 2024-12-19
US20240316159A1 (en) 2024-09-26
MX2025002188A (es) 2025-04-02
ZA202503388B (en) 2025-09-25
ZA202503387B (en) 2025-09-25
WO2019072941A1 (en) 2019-04-18
CN119838000A (zh) 2025-04-18
AU2025203535A1 (en) 2025-06-05
CL2020000812A1 (es) 2020-08-14
IL273470A (en) 2020-05-31
US12029779B2 (en) 2024-07-09
PH12020550185A1 (en) 2021-03-01
AU2018348929A1 (en) 2020-05-07
TWI842681B (zh) 2024-05-21
EP3694538A1 (en) 2020-08-19
AU2018348929B2 (en) 2025-02-27
BR112020006246A2 (pt) 2021-03-30
ZA202503350B (en) 2025-09-25
CA3078652A1 (en) 2019-04-18
MX2025002189A (es) 2025-04-02
US20250235511A1 (en) 2025-07-24
CN120241968A (zh) 2025-07-04
TW201914611A (zh) 2019-04-16
JP7475398B2 (ja) 2024-04-26
JP2020536854A (ja) 2020-12-17
MX2020003049A (es) 2020-07-27

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