JP7120018B2 - 眼科用製品及び粘度低下抑制方法 - Google Patents

眼科用製品及び粘度低下抑制方法 Download PDF

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Publication number
JP7120018B2
JP7120018B2 JP2018543965A JP2018543965A JP7120018B2 JP 7120018 B2 JP7120018 B2 JP 7120018B2 JP 2018543965 A JP2018543965 A JP 2018543965A JP 2018543965 A JP2018543965 A JP 2018543965A JP 7120018 B2 JP7120018 B2 JP 7120018B2
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Prior art keywords
ophthalmic composition
castor oil
acid
container
polyoxyethylene
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JP2018543965A
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English (en)
Japanese (ja)
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JPWO2018066651A1 (ja
Inventor
隆 奥村
香菜 内藤
玲子 石井
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Lion Corp
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Lion Corp
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Publication of JPWO2018066651A1 publication Critical patent/JPWO2018066651A1/ja
Priority to JP2022093619A priority Critical patent/JP2022111328A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02WCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W90/00Enabling technologies or technologies with a potential or indirect contribution to greenhouse gas [GHG] emissions mitigation
    • Y02W90/10Bio-packaging, e.g. packing containers made from renewable resources or bio-plastics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
JP2018543965A 2016-10-07 2017-10-05 眼科用製品及び粘度低下抑制方法 Active JP7120018B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022093619A JP2022111328A (ja) 2016-10-07 2022-06-09 眼科用製品及び粘度低下抑制方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016199036 2016-10-07
JP2016199036 2016-10-07
PCT/JP2017/036293 WO2018066651A1 (ja) 2016-10-07 2017-10-05 眼科用製品及び粘度低下抑制方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022093619A Division JP2022111328A (ja) 2016-10-07 2022-06-09 眼科用製品及び粘度低下抑制方法

Publications (2)

Publication Number Publication Date
JPWO2018066651A1 JPWO2018066651A1 (ja) 2019-08-08
JP7120018B2 true JP7120018B2 (ja) 2022-08-17

Family

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JP2018543965A Active JP7120018B2 (ja) 2016-10-07 2017-10-05 眼科用製品及び粘度低下抑制方法
JP2022093619A Pending JP2022111328A (ja) 2016-10-07 2022-06-09 眼科用製品及び粘度低下抑制方法

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JP2022093619A Pending JP2022111328A (ja) 2016-10-07 2022-06-09 眼科用製品及び粘度低下抑制方法

Country Status (4)

Country Link
JP (2) JP7120018B2 (ko)
KR (1) KR20190065237A (ko)
TW (1) TWI746662B (ko)
WO (1) WO2018066651A1 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7310113B2 (ja) * 2017-10-04 2023-07-19 ライオン株式会社 眼科用組成物及びその製造方法、ならびに吸着抑制方法
JP2019214560A (ja) * 2018-06-08 2019-12-19 ロート製薬株式会社 洗眼剤組成物
MA53171A (fr) 2018-07-18 2021-05-26 Atg 20 S R L Composition comprenant de la glycyrrhizine et ses utilisations cosmétiques et pharmaceutiques
CN114533652A (zh) * 2018-09-25 2022-05-27 沈阳兴齐眼科医院有限公司 药物组合物、其制备方法和用途
JP2020196672A (ja) * 2019-05-31 2020-12-10 小林製薬株式会社 ビタミンb12類含有組成物
JP2022099573A (ja) * 2020-12-23 2022-07-05 小林製薬株式会社 洗眼用組成物
WO2024110023A1 (en) * 2022-11-23 2024-05-30 Symrise Ag An active composition comprising retinol

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013183778A1 (ja) 2012-06-08 2013-12-12 ライオン株式会社 粘膜用組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10193490A (ja) * 1997-01-06 1998-07-28 Mitsubishi Gas Chem Co Inc 水性液状物質の包装方法
JPH1171478A (ja) 1997-08-29 1999-03-16 Santen Pharmaceut Co Ltd 粘度低下防止方法
JP2003113078A (ja) * 2001-09-28 2003-04-18 Lion Corp 眼科用製剤
JP4544391B2 (ja) * 2001-12-28 2010-09-15 ライオン株式会社 眼科用組成物
JP2004123634A (ja) * 2002-10-03 2004-04-22 Lion Corp 眼科用組成物
JP5382972B2 (ja) 2003-12-26 2014-01-08 ロート製薬株式会社 粘度低下が防止された組成物
JP5382973B2 (ja) 2003-12-26 2014-01-08 ロート製薬株式会社 粘度低下が防止された組成物
JP5513702B2 (ja) * 2004-05-07 2014-06-04 ロート製薬株式会社 抗菌点眼剤
JP5196130B2 (ja) * 2005-12-27 2013-05-15 ライオン株式会社 ソフトコンタクトレンズ用組成物及び吸着抑制方法
JP2006187636A (ja) * 2006-02-01 2006-07-20 Terumo Corp ビタミンb1類含有水性製剤の安定化方法
JP2011021002A (ja) * 2009-06-16 2011-02-03 Lion Corp 眼科用組成物
JP5673531B2 (ja) * 2009-06-30 2015-02-18 ライオン株式会社 眼科用組成物
JP2013237638A (ja) * 2012-05-15 2013-11-28 Lion Corp 眼科組成物
JP6260230B2 (ja) * 2013-11-28 2018-01-17 ライオン株式会社 眼科用組成物
CN104127377A (zh) * 2014-08-04 2014-11-05 珠海亿胜生物制药有限公司 一种不含抑菌剂的双氯芬酸钠滴眼液及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013183778A1 (ja) 2012-06-08 2013-12-12 ライオン株式会社 粘膜用組成物

Also Published As

Publication number Publication date
JPWO2018066651A1 (ja) 2019-08-08
KR20190065237A (ko) 2019-06-11
WO2018066651A1 (ja) 2018-04-12
TWI746662B (zh) 2021-11-21
JP2022111328A (ja) 2022-07-29
TW201813669A (zh) 2018-04-16

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