JP7054529B2 - Ｃｘｃｒ４阻害剤およびその使用 - Google Patents

Ｃｘｃｒ４阻害剤およびその使用 Download PDF

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JP7054529B2
JP7054529B2 JP2018566969A JP2018566969A JP7054529B2 JP 7054529 B2 JP7054529 B2 JP 7054529B2 JP 2018566969 A JP2018566969 A JP 2018566969A JP 2018566969 A JP2018566969 A JP 2018566969A JP 7054529 B2 JP7054529 B2 JP 7054529B2
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compound
cancer
ring
tumor
pharmaceutically acceptable
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JP2019518767A5 (enExample
JP2019518767A (ja
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エリス マリー ジョゼ ボーク，
レナト スケール，
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エックス４ ファーマシューティカルズ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2018566969A 2016-06-21 2017-06-21 Ｃｘｃｒ４阻害剤およびその使用 Active JP7054529B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022051875A JP7402549B2 (ja) 2016-06-21 2022-03-28 Ｃｘｃｒ４阻害剤およびその使用

Applications Claiming Priority (5)

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US201662352820P 2016-06-21 2016-06-21
US62/352,820 2016-06-21
US201762456526P 2017-02-08 2017-02-08
US62/456,526 2017-02-08
PCT/US2017/038609 WO2017223239A1 (en) 2016-06-21 2017-06-21 Cxcr4 inhibitors and uses thereof

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JP2019518767A JP2019518767A (ja) 2019-07-04
JP2019518767A5 JP2019518767A5 (enExample) 2020-07-16
JP7054529B2 true JP7054529B2 (ja) 2022-04-14

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US (4) US10759796B2 (enExample)
EP (2) EP3471727B1 (enExample)
JP (2) JP7054529B2 (enExample)
CN (2) CN116554168B (enExample)
CA (1) CA3027498A1 (enExample)
ES (1) ES2870920T3 (enExample)
WO (1) WO2017223239A1 (enExample)

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