JP7003044B2 - Angpt2およびpdgfbを標的化するrna複合体を用いる血管新生関連疾患の処置 - Google Patents
Angpt2およびpdgfbを標的化するrna複合体を用いる血管新生関連疾患の処置 Download PDFInfo
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- JP7003044B2 JP7003044B2 JP2018540030A JP2018540030A JP7003044B2 JP 7003044 B2 JP7003044 B2 JP 7003044B2 JP 2018540030 A JP2018540030 A JP 2018540030A JP 2018540030 A JP2018540030 A JP 2018540030A JP 7003044 B2 JP7003044 B2 JP 7003044B2
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662290330P | 2016-02-02 | 2016-02-02 | |
| US62/290,330 | 2016-02-02 | ||
| PCT/IB2017/000167 WO2017134526A1 (en) | 2016-02-02 | 2017-02-01 | Treatment of angiogenesis-associated diseases using rna complexes that target angpt2 and pdgfb |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019506862A JP2019506862A (ja) | 2019-03-14 |
| JP2019506862A5 JP2019506862A5 (https=) | 2020-03-12 |
| JP7003044B2 true JP7003044B2 (ja) | 2022-01-20 |
Family
ID=59386437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540030A Active JP7003044B2 (ja) | 2016-02-02 | 2017-02-01 | Angpt2およびpdgfbを標的化するrna複合体を用いる血管新生関連疾患の処置 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10519449B2 (https=) |
| EP (1) | EP3411481A4 (https=) |
| JP (1) | JP7003044B2 (https=) |
| KR (1) | KR102825945B1 (https=) |
| CN (1) | CN108779464B (https=) |
| CA (1) | CA3022877A1 (https=) |
| WO (1) | WO2017134526A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DK2631291T3 (da) | 2010-10-22 | 2019-06-11 | Olix Pharmaceuticals Inc | Nukleinsyremolekyler, der inducerer rna-interferens, og anvendelser deraf |
| CN108148838A (zh) | 2012-05-22 | 2018-06-12 | 奥利克斯医药有限公司 | 具有细胞内穿透能力的诱导rna干扰的核酸分子及用途 |
| EP4454637A3 (en) | 2015-11-16 | 2025-01-08 | Olix Pharmaceuticals, Inc. | Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3 |
| CA3022877A1 (en) | 2016-02-02 | 2017-08-10 | Olix Pharmaceuticals, Inc. | Treatment of angiogenesis-associated diseases using rna complexes that target angpt2 and pdgfb |
| KR102825946B1 (ko) | 2016-02-02 | 2025-06-27 | 올릭스 주식회사 | IL4Rα, TRPA1, 또는 F2RL1을 표적화하는 RNA 복합체를 사용한 아토피 피부염 및 천식의 치료 |
| WO2017178883A2 (en) | 2016-04-11 | 2017-10-19 | Olix Pharmaceuticals, Inc. | Treatment of idiopathic pulmonary fibrosis using rna complexes that target connective tissue growth factor |
| KR101916652B1 (ko) | 2016-06-29 | 2018-11-08 | 올릭스 주식회사 | 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도 |
| US11591600B2 (en) | 2017-02-10 | 2023-02-28 | OliX Pharmaceuticals. Inc. | Long double-stranded RNA for RNA interference |
| US20220380774A1 (en) * | 2019-05-20 | 2022-12-01 | Olix Pharmaceuticals, Inc. | Asymmetric sirna inhibiting expression of pd-1 |
| AU2024353921A1 (en) * | 2023-09-27 | 2026-04-16 | Neuro3 Therapeutics (Suzhou) Ltd. | Novel sirna constructs, therapeutics, and modifications |
| WO2025247332A1 (zh) * | 2024-05-31 | 2025-12-04 | 石药集团中奇制药技术(石家庄)有限公司 | 一种抑制vegfa基因和ang-2基因表达的双靶核酸分子 |
Citations (2)
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| CN108779464A (zh) | 2018-11-09 |
| KR20180104692A (ko) | 2018-09-21 |
| EP3411481A4 (en) | 2020-02-26 |
| US10519449B2 (en) | 2019-12-31 |
| JP2019506862A (ja) | 2019-03-14 |
| CA3022877A1 (en) | 2017-08-10 |
| US20200123548A1 (en) | 2020-04-23 |
| KR102825945B1 (ko) | 2025-06-30 |
| US20170218374A1 (en) | 2017-08-03 |
| WO2017134526A1 (en) | 2017-08-10 |
| EP3411481A1 (en) | 2018-12-12 |
| CN108779464B (zh) | 2022-05-17 |
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