JP6974168B2 - Pufa生成のための材料及び方法並びにpufa含有組成物 - Google Patents

Pufa生成のための材料及び方法並びにpufa含有組成物 Download PDF

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JP6974168B2
JP6974168B2 JP2017525878A JP2017525878A JP6974168B2 JP 6974168 B2 JP6974168 B2 JP 6974168B2 JP 2017525878 A JP2017525878 A JP 2017525878A JP 2017525878 A JP2017525878 A JP 2017525878A JP 6974168 B2 JP6974168 B2 JP 6974168B2
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desaturase
plant
content
seed
dna
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JP2018500885A (ja
Inventor
アンドレ,カール
エー. ハーテル,ハイコー
ゼンガー,トラルフ
バウアー,イェルク
ライン,ディートリッヒ
クンツェ,イレーネ
マーティ,ローレント
マケルヴァー,ジョン
イルマズ,ジェニー リンドバーグ
ブレマー,スティーブン
ブラゼール,スティーブン
ヴリンテン,パトリシア
スティムン,ステン
Original Assignee
ビーエーエスエフ プラント サイエンス カンパニー ゲーエムベーハー
バイオリジナル フード アンド サイエンス コーポレーション
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Application filed by ビーエーエスエフ プラント サイエンス カンパニー ゲーエムベーハー, バイオリジナル フード アンド サイエンス コーポレーション filed Critical ビーエーエスエフ プラント サイエンス カンパニー ゲーエムベーハー
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D7/00Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/02Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by the production or working-up
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19003Linoleoyl-CoA desaturase (1.14.19.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19006DELTA12-fatty-acid desaturase (1.14.19.6), i.e. oleoyl-CoA DELTA12 desaturase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y602/00Ligases forming carbon-sulfur bonds (6.2)
    • C12Y602/01Acid-Thiol Ligases (6.2.1)
    • C12Y602/01003Long-chain-fatty-acid-CoA ligase (6.2.1.3)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Animal Husbandry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017525878A 2014-11-14 2015-11-13 Pufa生成のための材料及び方法並びにpufa含有組成物 Expired - Fee Related JP6974168B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021134471A JP2021184744A (ja) 2014-11-14 2021-08-20 Pufa生成のための材料及び方法並びにpufa含有組成物
JP2023030778A JP2023081920A (ja) 2014-11-14 2023-03-01 Pufa生成のための材料及び方法並びにpufa含有組成物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462079622P 2014-11-14 2014-11-14
US62/079,622 2014-11-14
US201562234373P 2015-09-29 2015-09-29
US62/234,373 2015-09-29
PCT/EP2015/076631 WO2016075326A2 (en) 2014-11-14 2015-11-13 Materials and methods for pufa production, and pufa-containing compositions

Related Child Applications (1)

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JP2021134471A Division JP2021184744A (ja) 2014-11-14 2021-08-20 Pufa生成のための材料及び方法並びにpufa含有組成物

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JP2018500885A JP2018500885A (ja) 2018-01-18
JP6974168B2 true JP6974168B2 (ja) 2021-12-01

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Family Applications (7)

Application Number Title Priority Date Filing Date
JP2017525878A Expired - Fee Related JP6974168B2 (ja) 2014-11-14 2015-11-13 Pufa生成のための材料及び方法並びにpufa含有組成物
JP2017525981A Active JP7067926B2 (ja) 2014-11-14 2015-11-13 種子油においてトコフェロール含量を増加させるための材料および方法
JP2017525951A Active JP7423177B2 (ja) 2014-11-14 2015-11-13 Pufaを含有する植物性脂質の改質
JP2021134471A Pending JP2021184744A (ja) 2014-11-14 2021-08-20 Pufa生成のための材料及び方法並びにpufa含有組成物
JP2022042097A Withdrawn JP2022088464A (ja) 2014-11-14 2022-03-17 種子油においてトコフェロール含量を増加させるための材料および方法
JP2022067353A Pending JP2022106787A (ja) 2014-11-14 2022-04-15 Pufaを含有する植物性脂質の改質
JP2023030778A Pending JP2023081920A (ja) 2014-11-14 2023-03-01 Pufa生成のための材料及び方法並びにpufa含有組成物

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2017525981A Active JP7067926B2 (ja) 2014-11-14 2015-11-13 種子油においてトコフェロール含量を増加させるための材料および方法
JP2017525951A Active JP7423177B2 (ja) 2014-11-14 2015-11-13 Pufaを含有する植物性脂質の改質
JP2021134471A Pending JP2021184744A (ja) 2014-11-14 2021-08-20 Pufa生成のための材料及び方法並びにpufa含有組成物
JP2022042097A Withdrawn JP2022088464A (ja) 2014-11-14 2022-03-17 種子油においてトコフェロール含量を増加させるための材料および方法
JP2022067353A Pending JP2022106787A (ja) 2014-11-14 2022-04-15 Pufaを含有する植物性脂質の改質
JP2023030778A Pending JP2023081920A (ja) 2014-11-14 2023-03-01 Pufa生成のための材料及び方法並びにpufa含有組成物

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US (12) US11484560B2 (cg-RX-API-DMAC7.html)
EP (4) EP4151733A1 (cg-RX-API-DMAC7.html)
JP (7) JP6974168B2 (cg-RX-API-DMAC7.html)
KR (2) KR20170099884A (cg-RX-API-DMAC7.html)
CN (6) CN107532179B (cg-RX-API-DMAC7.html)
AU (12) AU2015344977B2 (cg-RX-API-DMAC7.html)
CA (5) CA2967708A1 (cg-RX-API-DMAC7.html)
CL (4) CL2017001221A1 (cg-RX-API-DMAC7.html)
EC (3) ECSP17036764A (cg-RX-API-DMAC7.html)
MX (4) MX388387B (cg-RX-API-DMAC7.html)
MY (1) MY184649A (cg-RX-API-DMAC7.html)
PH (4) PH12017500880A1 (cg-RX-API-DMAC7.html)
SG (1) SG11201703858YA (cg-RX-API-DMAC7.html)
WO (6) WO2016075310A1 (cg-RX-API-DMAC7.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015001505A2 (en) * 2013-07-05 2015-01-08 Basf Plant Science Company Gmbh Gene expression or activity enhancing elements
CN107532179B (zh) 2014-11-14 2021-10-15 巴斯夫植物科学有限公司 产生pufa的材料和方法及含有pufa的组合物
AR109245A1 (es) 2016-05-12 2018-11-14 Basf Plant Science Co Gmbh Métodos para optimizar la producción de metabolitos en plantas genéticamente modificadas y para procesar estas plantas
AU2017274414B2 (en) 2016-06-01 2021-10-28 Cargill, Incorporated Fish feed prepared from oilseed plants producing omega-3 fatty acids
EP3382029B1 (en) * 2017-03-31 2021-12-08 Toto Ltd. Recombinant mammalian cells and method for producing substance of interest
CA3096389A1 (en) 2018-04-13 2019-10-17 Cargill, Incorporated Method of cultivating lc-pufa containing transgenic brassica plants
EP3586642A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
AU2019336533A1 (en) * 2018-09-07 2021-03-25 Basf Plant Science Company Gmbh Improved method for the production of high levels of PUFA in plants
CA3057917A1 (en) 2018-10-16 2020-04-16 Monsanto Technology Llc Brassica event mon94100 and methods of use thereof
CN113423837B (zh) * 2019-02-14 2024-08-13 巴斯夫植物科学有限公司 产生提高的水平的多不饱和脂肪酸的芸苔属植物
CN114599224B (zh) * 2019-08-26 2023-12-08 纽希得营养澳大利亚私人有限公司 芥菜品系nubj1207
CN110699462B (zh) * 2019-11-06 2023-08-18 中国科学院南海海洋研究所 一种砗蚝微卫星位点及鉴定引物
EP4240144A1 (en) 2020-11-04 2023-09-13 BASF Plant Science Company GmbH Harvest management
EP4312517A1 (en) 2021-03-25 2024-02-07 BASF Plant Science Company GmbH Fertilizer management
CN113475400B (zh) * 2021-08-03 2022-07-12 吉安市林业科学研究所 双牌泡果荠的人工培养技术
EP4429476A1 (en) 2021-11-08 2024-09-18 Can Technologies, Inc. High plant pufa fish food
KR102721490B1 (ko) * 2022-02-17 2024-10-24 대한민국 유전자변형 면화를 검정하기 위한 양성대조군 플라스미드 및 이를 이용한 유전자변형 면화의 검정방법
KR102721484B1 (ko) * 2022-02-17 2024-10-24 대한민국 유전자변형 유채를 검정하기 위한 양성대조군 플라스미드 및 이를 이용한 유전자변형 유채의 검정방법
WO2024005187A1 (ja) 2022-07-01 2024-01-04 田辺三菱製薬株式会社 組成物、およびエダラボンの応答可能性の評価方法
CN117204282A (zh) * 2023-09-08 2023-12-12 中国农业科学院油料作物研究所 一种利用敌草快提高油菜籽生育酚含量的方法
CN119193346A (zh) * 2024-11-26 2024-12-27 南京师范大学 一种过表达溶血磷脂酸酰基转移酶基因的裂殖壶菌基因工程菌株及其构建方法和应用

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DK162399C (da) 1986-01-28 1992-03-23 Danisco Fremgangsmaade til ekspression af gener i baelgplanteceller, dna-fragment, rekombineret dna-fragment samt plasmid til brug ved udoevelsen af fremgangsmaaden
NZ228320A (en) 1988-03-29 1991-06-25 Du Pont Nucleic acid promoter fragments of the promoter region homologous to the em gene of wheat, dna constructs therefrom and plants thereof
US5364780A (en) 1989-03-17 1994-11-15 E. I. Du Pont De Nemours And Company External regulation of gene expression by inducible promoters
ES2163392T3 (es) 1990-03-16 2002-02-01 Calgene Llc Nuevas secuencias expresadas preferentemente en el desarrollo de semillas precoces, y procedimientos relacionados con las mismas.
EP0572603A1 (en) 1991-11-20 1993-12-08 Calgene, Inc. FATTY ACYL-CoA: FATTY ALCOHOL O-ACYLTRANSFERASES
DK0637339T3 (da) 1992-04-13 2001-12-03 Syngenta Ltd DNA-konstruktioner og planter, hvori de er inkorporeret
DE4228476C2 (de) 1992-08-27 2002-05-02 Cognis Deutschland Gmbh Verfahren zum Gewinnen von Tocopherol und/oder Sterin
GB9225845D0 (en) 1992-12-10 1993-02-03 Nickerson Biocem Ltd Modified plants
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
EP0741547B1 (en) 1994-01-26 2005-04-20 Kyphon Inc. Improved inflatable device for use in surgical protocol relating to fixation of bone
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US5910630A (en) 1994-04-06 1999-06-08 Davies; Huw Maelor Plant lysophosphatidic acid acyltransferases
GB9502468D0 (en) 1995-02-09 1995-03-29 Gene Shears Pty Ltd DNA Sequence
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
WO1998054302A2 (en) 1997-05-27 1998-12-03 Icos Corporation Human lysophosphatidic acid acyltransferase
WO1998054303A1 (en) 1997-05-27 1998-12-03 Cell Therapeutics, Inc. Mammalian lysophosphatidic acid acyltransferase
JP2002504819A (ja) 1997-06-05 2002-02-12 カルジーン エルエルシー ジアシルグリセロールトランスフェラーゼタンパク質
KR20010013426A (ko) 1997-06-05 2001-02-26 칼진 엘엘시 지방 아실-CoA: 지방 알코올 아실트란스페라제
ATE346944T1 (de) 1997-09-30 2006-12-15 Univ California Herstellung von proteinen in pflanzensamen
WO1999064616A2 (en) 1998-06-12 1999-12-16 Abbott Laboratories Polyunsaturated fatty acids in plants
CA2343969A1 (en) 1998-09-25 2000-04-06 Calgene Llc Novel plant acyltransferases
US6572830B1 (en) 1998-10-09 2003-06-03 Motorola, Inc. Integrated multilayered microfludic devices and methods for making the same
US6303849B1 (en) 1998-11-12 2001-10-16 Saskatchewan Wheat Pool Brassica juncea lines bearing endogenous edible oils
US6342657B1 (en) * 1999-05-06 2002-01-29 Rhone-Poulenc Agro Seed specific promoters
US6509516B1 (en) 1999-10-29 2003-01-21 Plant Genetic Systems N.V. Male-sterile brassica plants and methods for producing same
PT1240340E (pt) * 1999-12-16 2012-08-01 Monsanto Technology Llc Construções de dna para expressão de polipéptidos heterólogos em plantas
BR0108198A (pt) 2000-02-09 2003-03-25 Basf Ag ácido nucleico isolado, construção de gene, sequência de aminoácidos, vetor, organismo, anticorpo, molécula de ácido nucleico anti-sentido, processo para a preparação de pufas, óleo, lipìdeo ou ácido graxo ou uma fração destes, composição, uso da composição oleaginosa, lipìdica ou de ácido graxo, kit, e, processo para identificar um antagonista de elongases
BRPI0100752B1 (pt) 2000-06-22 2015-10-13 Monsanto Co moléculas e pares de moléculas de dna, processos para detectar molécula de dna e para criar um traço tolerante a glifosato em plantas de milho, bem como kit de detecção de dna
GB0316629D0 (en) 2003-07-16 2003-08-20 Univ York Transgenic cell
EP1322752B2 (en) 2000-09-28 2015-02-11 Bioriginal Food & Science Corp. Fad4, fad5, fad5-2, and fad6, fatty acid desaturase family members and uses thereof
PL214848B1 (pl) 2000-09-29 2013-09-30 Monsanto Technology Llc Sposób wytwarzania tolerancyjnej na glifosat rosliny pszenicy, plodna tolerujaca glifosat roslina pszenicy, nasiono pszenicy, para czasteczek DNA, sposób wykrywania obecnosci diagnostycznej czasteczki DNA, sposób wykrywania sekwencji zawierajacej okreslone nukleotydy, sposób wytwarzania rosliny pszenicy z tolerancja glifosatu, zestaw do wykrywania DNA, nasiono transgenicznej pszenicy, roslina pszenicy wytworzona przez hodowle nasion, sposób wytwarzania rosliny pszenicy tolerujacej stosowanie glifosatu, sposób selektywnego kontrolowania chwastów na polu zawierajacym uprawe pszenicy, czasteczka DNA, roslina pszenicy tolerujaca glifosat, roslina zdolna do wytwarzania diagnostycznego amplikonu, nasiono, komórka
US6740488B2 (en) 2000-10-25 2004-05-25 Monsanto Technology Llc Cotton event PV-GHGT07(1445) compositions and methods for detection thereof
US20030024005A1 (en) 2000-11-17 2003-01-30 Hillyard Jeanna R. Cotton event PV-GHBK04 (757) and compositions and methods for detection thereof
US6733974B1 (en) 2000-12-01 2004-05-11 Monsanto Technology, Llc Methods and compositions for detection of specific genetic constructs in plant transformation events
GB0031558D0 (en) 2000-12-22 2001-02-07 Biogemma Uk Ltd Elongase promoters
CA2680376C (en) 2001-06-06 2016-11-15 Bioriginal Food & Science Corporation Flax (linum usitatissimum l.) seed-specific promoters
US6818807B2 (en) 2001-08-06 2004-11-16 Bayer Bioscience N.V. Herbicide tolerant cotton plants having event EE-GH1
AU2002324856A1 (en) * 2001-08-29 2003-03-10 Xenon Genetics Inc. High throughput screening assays using fatty acid synthetic enzymes
CN1267174C (zh) * 2001-12-12 2006-08-02 马泰克生物科学博尔德公司 从含油种子和微生物来源提取和冬化脂类的方法
JP4100494B2 (ja) * 2002-02-05 2008-06-11 独立行政法人理化学研究所 種子成熟後期及び発芽期特異的誘導性プロモーター
WO2003078639A2 (en) 2002-03-16 2003-09-25 The University Of York Transgenic plants expressing enzymes involved in fatty acid biosynthesis
AU2003234128A1 (en) 2002-04-17 2003-11-03 Sangamo Biosciences, Inc. Compositions and methods for regulation of plant gamma-tocopherol methyltransferase
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
US7423198B2 (en) 2002-05-15 2008-09-09 Viterra, Inc. High oleic acid Brassica juncea
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
CA2868312A1 (en) 2003-03-31 2004-10-14 University Of Bristol Novel plant acyltransferases specific for long-chained, multiply unsaturated fatty acids
WO2004090123A2 (de) 2003-04-08 2004-10-21 Basf Plant Science Gmbh Δ-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle
MXPA05012482A (es) 2003-05-20 2006-07-03 Investigen Inc Sistema para detectar polinucleotidos.
MX342029B (es) 2003-08-01 2016-09-12 Basf Plant Science Gmbh * Metodo para la produccion de acidos grasos poli - insaturados en organismos transgenicos.
PL1720988T3 (pl) 2004-02-27 2012-05-31 Basf Plant Science Gmbh Sposób wytwarzania nienasyconych kwasów tłuszczowych omega-3 w organizmach transgenicznych
EP1723220B1 (de) 2004-02-27 2013-04-10 BASF Plant Science GmbH Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen pflanzen
JP4567047B2 (ja) 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
WO2005118814A2 (en) 2004-06-04 2005-12-15 Fluxome Sciences A/S Metabolically engineered cells for the production of polyunsaturated fatty acids
EP1758991B1 (en) 2004-06-25 2013-01-16 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
DE102004060340A1 (de) 2004-07-16 2006-02-09 Basf Plant Science Gmbh Verfahren zur Erhöhung des Gehalts an mehrfach ungesättigten langkettigen Fettsäuren in transgenen Organismen
WO2006024023A2 (en) 2004-08-24 2006-03-02 Nanomix, Inc. Nanotube sensor devices for dna detection
AU2005279359B2 (en) 2004-09-02 2011-08-11 Basf Plant Science Gmbh Disarmed agrobacterium strains, Ri-plasmids, and methods of transformation based thereon
US20060068398A1 (en) 2004-09-24 2006-03-30 Cepheid Universal and target specific reagent beads for nucleic acid amplification
CN101098628B (zh) * 2004-11-04 2010-09-01 孟山都技术公司 种子油组合物
PL1809118T3 (pl) 2004-11-04 2017-07-31 Monsanto Technology Llc Kompozycje oleju z nasion
DE102004063326A1 (de) 2004-12-23 2006-07-06 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
DE102006008030A1 (de) 2006-02-21 2007-08-23 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten Fettsäuren
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
AU2007287585B2 (en) 2006-08-24 2013-08-29 Basf Plant Science Gmbh Isolation and characterization of a novel Pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
US7371930B1 (en) 2006-12-15 2008-05-13 Shamrock Seed Company, Inc. Lettuce cultivar 21-0406127-B
EP2134159B1 (en) 2007-04-04 2017-06-21 BASF Plant Science GmbH Ahas mutants
CA2695112A1 (en) 2007-07-31 2009-02-05 Basf Plant Science Gmbh Elongases and processes for the production of polyunsaturated fatty acids in transgenic organisms
EP3260543A1 (en) 2008-02-15 2017-12-27 Monsanto Technology LLC Soybean plant and seed corresponding to transgenic event mon87769 and methods for detection thereof
BRPI0908267B8 (pt) 2008-02-29 2019-02-05 Monsanto Technology Llc método de produção de uma planta de milho tolerante a seca
US8455035B2 (en) 2008-04-25 2013-06-04 Basf Plant Science Gmbh Plant seed oil
CA2723072C (en) 2008-04-30 2017-01-10 Rothamsted Research Ltd. Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
EP2826864B1 (en) * 2008-07-01 2018-04-18 BASF Plant Science GmbH Promoters from Brassica napus for seed specific gene expression
US9090902B2 (en) * 2008-08-26 2015-07-28 Basf Plant Science Gmbh Nucleic acids encoding desaturases and modified plant oil
AU2009317860B2 (en) 2008-11-18 2014-03-27 Commonwealth Scientific And Industrial Research Organisation Enzymes and methods for producing omega-3 fatty acids
PL2376638T3 (pl) 2008-12-12 2014-01-31 Basf Plant Science Gmbh Desaturazy oraz sposób wytwarzania wielonienasyconych kwasów tłuszczowych w organizmach transgenicznych
CA2768082C (en) * 2009-07-17 2020-07-21 Basf Plant Science Company Gmbh Novel fatty acid desaturases and uses thereof
TW201144442A (en) 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
US9388437B2 (en) 2010-06-25 2016-07-12 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
US20120040076A1 (en) 2010-08-11 2012-02-16 E. I. Du Pont De Nemours And Company Aquaculture feed compositions
AU2012262172B2 (en) * 2011-05-31 2016-03-31 Cargill, Incorporated Oxidatively-stabilized fats containing very long-chain omega-3 polyunsaturated fatty acids
CA2840550A1 (en) 2011-07-22 2013-01-31 Basf Plant Science Company Gmbh Plant transformation method
WO2013049227A2 (en) 2011-09-26 2013-04-04 Geneart Ag High efficiency, small volume nucleic acid synthesis
KR20140116445A (ko) 2011-12-30 2014-10-02 다우 아그로사이언시즈 엘엘씨 카놀라 가공 동안의 dha 유지
EP2836599B1 (en) * 2012-04-12 2019-11-06 Rothamsted Research Limited Production of omega-3 long chain polyunsaturated fatty acids
AU2013251382A1 (en) * 2012-04-27 2014-10-16 Synthetic Genomics, Inc. Compositions and methods for modulating the sensitivity of cells to AHAS inhibitors
US8816111B2 (en) 2012-06-15 2014-08-26 Commonwealth Scientific And Industrial Research Organisation Lipid comprising polyunsaturated fatty acids
CN102719552B (zh) * 2012-07-16 2013-12-04 上海市农业科学院 一种转基因香石竹Moonshade的品系特异性定性、定量PCR检测方法
BR102014029437A2 (pt) 2013-11-26 2015-07-07 Dow Agrosciences Llc Produção de ácidos graxos ômega-3 polinsaturados de cadeia longa em culturas oleaginosas por uma pufa sintase de traustoquitrídio
AU2014366839B2 (en) 2013-12-18 2021-07-01 Commonwealth Scientific And Industrial Research Organisation Lipid comprising long chain polyunsaturated fatty acids
CN107532179B (zh) 2014-11-14 2021-10-15 巴斯夫植物科学有限公司 产生pufa的材料和方法及含有pufa的组合物

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