JP6938628B2 - 造血器型プロスタグランジンｄシンターゼ阻害剤としての１，３二置換シクロブタンまたはアゼチジン誘導体 - Google Patents

造血器型プロスタグランジンｄシンターゼ阻害剤としての１，３二置換シクロブタンまたはアゼチジン誘導体 Download PDF

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JP6938628B2
JP6938628B2 JP2019520150A JP2019520150A JP6938628B2 JP 6938628 B2 JP6938628 B2 JP 6938628B2 JP 2019520150 A JP2019520150 A JP 2019520150A JP 2019520150 A JP2019520150 A JP 2019520150A JP 6938628 B2 JP6938628 B2 JP 6938628B2
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trans
muscle
mmol
substituted
azetidine
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JP2019536757A5 (enExample
JP2019536757A (ja
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デイビッド、ノーマン、ディートン
ユ、グオ
アシュリー、ポール、ハンコック
クリスティ、シュルテ
バリー、ジョージ、シアラー
エミリー、デスパニエ、スミス
ユージン、エル．スチュワート
ステファン、アンドリュー、トムソン
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GlaxoSmithKline Intellectual Property Development Ltd
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
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    • A61K31/42—Oxazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
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  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
JP2019520150A 2016-10-13 2017-10-12 造血器型プロスタグランジンｄシンターゼ阻害剤としての１，３二置換シクロブタンまたはアゼチジン誘導体 Expired - Fee Related JP6938628B2 (ja)

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US201662407634P 2016-10-13 2016-10-13
US62/407,634 2016-10-13
PCT/IB2017/056320 WO2018069863A1 (en) 2016-10-13 2017-10-12 1,3 di-substituted cyclobutane or azetidine derivatives as hematopoietic prostaglandin d synthase inhibitors

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CA3038756A1 (en) 2018-04-19
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CR20190174A (es) 2019-08-21
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AU2017342156A1 (en) 2019-04-18
CL2019000986A1 (es) 2019-06-21
US20190241554A1 (en) 2019-08-08
BR112019007609A2 (pt) 2019-07-02
JP2019536757A (ja) 2019-12-19
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WO2018069863A1 (en) 2018-04-19
JOP20190072A1 (ar) 2019-04-07

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