KR20190072565A - 조혈 프로스타글란딘 d 신타제 억제제로서의 1,3 이치환된 시클로부탄 또는 아제티딘 유도체 - Google Patents
조혈 프로스타글란딘 d 신타제 억제제로서의 1,3 이치환된 시클로부탄 또는 아제티딘 유도체 Download PDFInfo
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- KR20190072565A KR20190072565A KR1020197013195A KR20197013195A KR20190072565A KR 20190072565 A KR20190072565 A KR 20190072565A KR 1020197013195 A KR1020197013195 A KR 1020197013195A KR 20197013195 A KR20197013195 A KR 20197013195A KR 20190072565 A KR20190072565 A KR 20190072565A
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- South Korea
- Prior art keywords
- trans
- yloxy
- cyclobutanecarboxamide
- thiazol
- substituted
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- Ceased
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Images
Classifications
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
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| EP3638672A1 (en) * | 2017-06-13 | 2020-04-22 | GlaxoSmithKline Intellectual Property Development Limited | Chemical compounds as h-pgds inhibitors |
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| PT3676297T (pt) | 2017-09-01 | 2023-08-29 | Denali Therapeutics Inc | Compostos, composições e métodos |
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| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
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| CN111549000B (zh) * | 2020-06-18 | 2022-07-29 | 中国医学科学院整形外科医院 | 一种过表达Hpgds的重组脂肪干细胞、制备方法及其应用 |
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| US20190241554A1 (en) | 2019-08-08 |
| MA46531A (fr) | 2019-08-21 |
| EA201990904A1 (ru) | 2019-08-30 |
| EP3526206A1 (en) | 2019-08-21 |
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