JP6925127B2 - 細胞培養物を処理する方法およびシステム - Google Patents

細胞培養物を処理する方法およびシステム Download PDF

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JP6925127B2
JP6925127B2 JP2016542875A JP2016542875A JP6925127B2 JP 6925127 B2 JP6925127 B2 JP 6925127B2 JP 2016542875 A JP2016542875 A JP 2016542875A JP 2016542875 A JP2016542875 A JP 2016542875A JP 6925127 B2 JP6925127 B2 JP 6925127B2
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conduit
cell
days
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JP2016530893A (ja
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ハン・ジョウ
ベンジャミン・ライト
マーシェラ・ユー
ジン・イン
コンスタンティン・コンスタンティノフ
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Genzyme Corp
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    • C—CHEMISTRY; METALLURGY
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    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
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    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
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    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • C—CHEMISTRY; METALLURGY
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Water Supply & Treatment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2016542875A 2013-09-16 2014-09-16 細胞培養物を処理する方法およびシステム Active JP6925127B2 (ja)

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US201361878502P 2013-09-16 2013-09-16
US61/878,502 2013-09-16
PCT/US2014/055897 WO2015039115A1 (en) 2013-09-16 2014-09-16 Methods and systems for processing a cell culture

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JP2016530893A JP2016530893A (ja) 2016-10-06
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JP2020073759A Active JP7008746B2 (ja) 2013-09-16 2020-04-17 細胞培養物を処理する方法およびシステム
JP2022001359A Active JP7227406B2 (ja) 2013-09-16 2022-01-07 細胞培養物を処理する方法およびシステム
JP2023017253A Active JP7685543B2 (ja) 2013-09-16 2023-02-08 細胞培養物を処理する方法およびシステム

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JP2023017253A Active JP7685543B2 (ja) 2013-09-16 2023-02-08 細胞培養物を処理する方法およびシステム

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US (2) US20150158907A1 (enExample)
EP (1) EP3047013B1 (enExample)
JP (4) JP6925127B2 (enExample)
KR (3) KR20230142653A (enExample)
CN (2) CN113444620B (enExample)
AU (4) AU2014318420B2 (enExample)
BR (2) BR112016005545B1 (enExample)
CA (1) CA2924332C (enExample)
CY (1) CY1124684T1 (enExample)
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EA (2) EA035665B1 (enExample)
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HU (1) HUE055888T2 (enExample)
IL (1) IL244552B (enExample)
MX (2) MX384020B (enExample)
SG (2) SG11201601899TA (enExample)
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