CY1124684T1 - Μεθοδοι και συστηματα για την επεξεργασια μιας κυτταρικης καλλιεργειας - Google Patents
Μεθοδοι και συστηματα για την επεξεργασια μιας κυτταρικης καλλιεργειαςInfo
- Publication number
- CY1124684T1 CY1124684T1 CY20211100884T CY211100884T CY1124684T1 CY 1124684 T1 CY1124684 T1 CY 1124684T1 CY 20211100884 T CY20211100884 T CY 20211100884T CY 211100884 T CY211100884 T CY 211100884T CY 1124684 T1 CY1124684 T1 CY 1124684T1
- Authority
- CY
- Cyprus
- Prior art keywords
- cell culture
- methods
- processing
- systems
- filtration
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/10—Separation or concentration of fermentation products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/12—Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Water Supply & Treatment (AREA)
- Immunology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361878502P | 2013-09-16 | 2013-09-16 | |
| PCT/US2014/055897 WO2015039115A1 (en) | 2013-09-16 | 2014-09-16 | Methods and systems for processing a cell culture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1124684T1 true CY1124684T1 (el) | 2022-07-22 |
Family
ID=51660627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20211100884T CY1124684T1 (el) | 2013-09-16 | 2021-10-13 | Μεθοδοι και συστηματα για την επεξεργασια μιας κυτταρικης καλλιεργειας |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US20150158907A1 (enExample) |
| EP (1) | EP3047013B1 (enExample) |
| JP (4) | JP6925127B2 (enExample) |
| KR (3) | KR102749545B1 (enExample) |
| CN (2) | CN113444620B (enExample) |
| AU (4) | AU2014318420B2 (enExample) |
| BR (2) | BR112016005545B1 (enExample) |
| CA (1) | CA2924332C (enExample) |
| CY (1) | CY1124684T1 (enExample) |
| DK (1) | DK3047013T3 (enExample) |
| EA (2) | EA031652B1 (enExample) |
| ES (1) | ES2891728T3 (enExample) |
| HU (1) | HUE055888T2 (enExample) |
| IL (1) | IL244552B (enExample) |
| MX (2) | MX384020B (enExample) |
| SG (2) | SG10201803601SA (enExample) |
| WO (1) | WO2015039115A1 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201806083RA (en) | 2013-02-22 | 2018-08-30 | Genzyme Corp | Microcarrier perfusion culturing methods and uses thereof |
| HUE042094T2 (hu) | 2013-02-22 | 2019-06-28 | Genzyme Corp | Mikrokarrier-perfúziós tenyésztési eljárások és alkalmazásuk |
| EP4218991A1 (en) | 2014-05-13 | 2023-08-02 | Amgen Inc. | Process control systems and methods for use with filters and filtration processes |
| TWI743024B (zh) | 2014-06-06 | 2021-10-21 | 美商健臻公司 | 灌注培養方法及其用途 |
| TWI707949B (zh) | 2014-06-09 | 2020-10-21 | 美商健臻公司 | 種子罐培養法（ｓｅｅｄ ｔｒａｉｎ ｐｒｏｃｅｓｓｅｓ）及其用途 |
| KR102465762B1 (ko) * | 2014-10-24 | 2022-11-09 | 젠자임 코포레이션 | 멸균 공정 용기로부터의 유체 스트림에 대한 통합형 연속식 단리 |
| SG10202001034PA (en) | 2014-12-22 | 2020-04-29 | Genzyme Corp | Methods of culturing a mammalian cell |
| JP6457338B2 (ja) * | 2015-05-28 | 2019-01-23 | 株式会社日立製作所 | 液体還流容器、細胞濃縮装置及び細胞濃縮システム |
| EP3397282A4 (en) | 2015-12-30 | 2019-08-07 | Momenta Pharmaceuticals, Inc. | METHODS RELATING TO BIOLOGICA |
| ITUB20160272A1 (it) * | 2016-01-22 | 2017-07-22 | Univ Degli Studi Di Palermo | Bioreattore a perfusione autosufficiente monouso per crescite cellulari 3D |
| US20200289987A1 (en) * | 2016-03-14 | 2020-09-17 | Pendotech | Processing System for Multiple Tangential Flow Filtration Stations in Bioprocessing Applications |
| WO2017180814A1 (en) * | 2016-04-15 | 2017-10-19 | Boehringer Ingelheim International Gmbh | Cell retention device and method |
| US11473047B2 (en) | 2016-07-19 | 2022-10-18 | The Automation Partnership (Cambridge) Limited | Liquid filtration and pump system |
| CN109415669B (zh) * | 2016-07-19 | 2023-01-31 | 自动化合作关系（剑桥）有限公司 | 可逆液体过滤系统 |
| CN106047707B (zh) * | 2016-08-03 | 2018-11-13 | 广州赛泊泰生物技术有限公司 | 贴壁/悬浮型细胞培养单元、装置、系统及方法 |
| TWI675696B (zh) | 2017-06-01 | 2019-11-01 | 美商Ｅｍｄ密理博公司 | 用於灌注應用之切向流過濾裝置 |
| EP4039786A1 (en) * | 2017-10-16 | 2022-08-10 | Regeneron Pharmaceuticals, Inc. | Perfusion bioreactor and related methods of use |
| EP3714033A1 (en) | 2017-11-22 | 2020-09-30 | Corning Incorporated | Perfusion bioreactor system and perfusion cell culture method |
| US12252682B2 (en) | 2018-02-09 | 2025-03-18 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US11932842B2 (en) | 2018-02-09 | 2024-03-19 | Global Life Sciences Solutions Usa Llc | Bioprocessing apparatus |
| US10889792B2 (en) | 2018-02-09 | 2021-01-12 | Global Life Sciences Solutions Usa Llc | Cell expansion vessel systems and methods |
| US11414639B2 (en) | 2018-02-09 | 2022-08-16 | Global Life Sciences Solutions Usa Llc | Bioprocessing vessel |
| US11920119B2 (en) | 2018-02-09 | 2024-03-05 | Global Life Sciences Solutions Usa Llc | Systems and methods for bioprocessing |
| JP7520322B2 (ja) * | 2018-02-09 | 2024-07-23 | グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー | 細胞療法のためのバイオプロセッシング方法 |
| US11371007B2 (en) * | 2018-02-09 | 2022-06-28 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US12077743B2 (en) | 2018-02-09 | 2024-09-03 | Global Life Sciences Solutions Usa Llc | Apparatus for fluid line management in a bioprocessing system |
| CN110241012B (zh) * | 2018-03-09 | 2022-11-01 | 嘉和生物药业有限公司 | 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用 |
| TWI846694B (zh) * | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| US20210214702A1 (en) * | 2018-06-01 | 2021-07-15 | Gennova Biopharmaceuticals Limited | Process for production of recombinant tnk-tpa by packed-bed perfusion system |
| US12565635B2 (en) | 2018-08-29 | 2026-03-03 | Cytiva Sweden Ab | Method of operation of a perfusion system |
| US12595454B2 (en) * | 2018-09-06 | 2026-04-07 | Momenta Pharmaceuticals, Inc. | Methods of continuous cell culture |
| JP2022500242A (ja) * | 2018-09-21 | 2022-01-04 | サイティバ・スウェーデン・アクチボラグ | 灌流バイオプロセシングシステムおよびそれを動作させる方法 |
| JP7707062B2 (ja) * | 2018-11-02 | 2025-07-14 | ウーシー バイオロジクス アイルランド リミテッド | 連続的採取を行い細胞流出を行わない強化灌流による細胞培養法 |
| US10647954B1 (en) | 2018-11-15 | 2020-05-12 | Flaskworks, Llc | Dendritic cell generating apparatus and method |
| IL284374B2 (en) | 2018-12-31 | 2025-10-01 | Momenta Pharmaceuticals Inc | Methods for producing ozatekinumab |
| CA3126717A1 (en) * | 2019-01-25 | 2020-07-30 | Becton, Dickinson And Company | Methods and apparatus to selectively extract constituents from biological samples |
| AU2020253327B2 (en) | 2019-04-01 | 2025-04-10 | Boehringer Ingelheim International Gmbh | Integrated and continuous recombinant protein manufacturing |
| WO2020258706A1 (zh) * | 2019-06-28 | 2020-12-30 | 信达生物制药(苏州)有限公司 | 组合式层析装置、无缝连接层析方法和生物制剂的纯化方法 |
| US11566217B2 (en) | 2019-08-13 | 2023-01-31 | Flaskworks, Llc | Duty cycle for cell culture systems |
| CN114901799A (zh) | 2019-10-21 | 2022-08-12 | 弗拉斯沃克斯有限责任公司 | 用于细胞培养的系统和方法 |
| DE102019134489B4 (de) * | 2019-12-16 | 2024-08-22 | Fachhochschule Südwestfalen, Köperschaft des öffentlichen Rechts | Phagenkultivierungsvorrichtung, Verfahren zur Präparation von Phagen und Filtervorrichtung dafür |
| US20230120489A1 (en) * | 2020-03-06 | 2023-04-20 | Yukuan Shang | Perfusion module and perfusion culture system |
| EP3878542A1 (en) * | 2020-03-11 | 2021-09-15 | Bayer AG | Filter membranes as antifoam level safeguards |
| KR102230957B1 (ko) * | 2020-05-18 | 2021-03-23 | 경북대학교 산학협력단 | Ev 여과장치 |
| US12408660B2 (en) * | 2020-07-08 | 2025-09-09 | Vascular Perfusion Solutions, Inc. | Reciprocating pressure perfusion system and methods |
| EP4182427A1 (en) * | 2020-07-15 | 2023-05-24 | Global Life Sciences Solutions USA LLC | Bioprocessing perfusion system having a plurality of filters and method of operating the same |
| CN114058505B (zh) * | 2020-07-30 | 2024-10-01 | 环球生命科技咨询美国有限责任公司 | 新型灌流培养用高密度微载体截留装置和使用方法 |
| US20220119759A1 (en) * | 2020-10-19 | 2022-04-21 | Emd Millipore Corporation | Cascade Tangential Flow Filtration Systems for Perfusion of Cell Culture |
| US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12151024B2 (en) | 2021-01-22 | 2024-11-26 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| CN112831416B (zh) * | 2021-01-29 | 2025-01-10 | 上海睿钰生物科技有限公司 | 一种体外生命维持灌流培养系统及其控制方法 |
| EP4313356A4 (en) | 2021-04-16 | 2025-02-19 | Repligen Corporation | Filtration system and method |
| WO2022229381A1 (en) * | 2021-04-29 | 2022-11-03 | Univercells Technologies Sa | Systems and methods for the continuous production and purification of biologics |
| EP4370647A1 (en) | 2021-07-15 | 2024-05-22 | Just-Evotec Biologics, Inc. | Bidirectional tangential flow filtration (tff) perfusion system |
| EP4415713A4 (en) | 2021-10-14 | 2025-08-06 | Pacira Pharmaceuticals Inc | MULTIVESICULAR LIPOSOME FORMULATIONS OF BUPIVACAINE AND THEIR USES |
| EP4174164A1 (en) * | 2021-10-21 | 2023-05-03 | Alit Biotech (Shanghai) Co., Ltd. | Biological filtration systems and controlling methods thereof |
| US12522797B2 (en) | 2022-04-12 | 2026-01-13 | Sartorius Stedim Biotech Gmbh | Multiport device for connecting a loop to one port of a bioreactor, and perfusion or concentrated fed-batch setup for performing an upstream process of cell culture |
| EP4268943A1 (en) | 2022-04-27 | 2023-11-01 | Levitronix GmbH | A device for tangential flow filtration of a fluid |
| EP4608965A4 (en) * | 2022-10-26 | 2026-02-25 | Nat Resilience Llc | BIOREACTOR SYSTEMS AND THEIR OPERATING PROCESSES |
| WO2025070513A1 (ja) | 2023-09-27 | 2025-04-03 | 富士フイルム株式会社 | 細胞培養液の処理装置、処理方法、及び産生物の製造方法 |
| US20250129321A1 (en) * | 2023-10-20 | 2025-04-24 | Cellares Corporation | Systems, devices, and methods for fluid control in a cell processing system |
| WO2025122785A1 (en) * | 2023-12-05 | 2025-06-12 | Massachusetts Institute Of Technology | Magnetic resonance relaxometry bioreactor monitoring |
| WO2025134151A1 (en) * | 2023-12-20 | 2025-06-26 | Omnibrx Biotechnologies Private Limited | An apparatus for cell retention and method thereof |
| GB202407177D0 (en) * | 2024-05-20 | 2024-07-03 | Ivy Farm Tech Limited | Perfusion cell culture apparatus |
| WO2025164695A1 (ja) * | 2024-02-01 | 2025-08-07 | 国立大学法人東京科学大学 | 細胞培養装置及びそれを用いた細胞培養方法 |
| US12280149B1 (en) | 2024-05-20 | 2025-04-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12156940B1 (en) | 2024-05-20 | 2024-12-03 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12251472B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60804A (ja) * | 1983-06-20 | 1985-01-05 | Poritetsukusu:Kk | ウルトラフイルタ装置 |
| JPS6188872A (ja) * | 1984-10-09 | 1986-05-07 | Snow Brand Milk Prod Co Ltd | 高濃度連続培養方法及び装置 |
| US4885087A (en) * | 1986-11-26 | 1989-12-05 | Kopf Henry B | Apparatus for mass transfer involving biological/pharmaceutical media |
| US6022742A (en) * | 1986-11-26 | 2000-02-08 | Kopf; Henry B. | Culture device and method |
| US5030346A (en) * | 1988-01-15 | 1991-07-09 | Henry Filters, Inc. | Pump for filtration system |
| US5401650A (en) * | 1990-10-24 | 1995-03-28 | The Mount Sinai School Of Medicine Of The City University Of New York | Cloning and expression of biologically active α-galactosidase A |
| JPH0531335A (ja) * | 1991-07-30 | 1993-02-09 | Toto Ltd | 分離膜洗浄方法 |
| US6544424B1 (en) | 1999-12-03 | 2003-04-08 | Refined Technology Company | Fluid filtration system |
| JP3547715B2 (ja) * | 2001-03-06 | 2004-07-28 | 榮 新垣 | ベクター精製用装置及び方法 |
| CN1713951B (zh) * | 2002-06-19 | 2010-05-26 | 西北生物治疗药物公司 | 切向流过滤设备和白细胞富集方法 |
| US7875448B2 (en) | 2004-01-12 | 2011-01-25 | Single Use Brx, Llc | Bioreactor systems and disposable bioreactor |
| CA2557046A1 (en) * | 2004-03-05 | 2005-10-13 | John Crowley | Process for cell culturing by continuous perfusion and alternating tangential flow |
| WO2007075283A2 (en) * | 2005-12-06 | 2007-07-05 | Amgen Inc. | Polishing steps used in multi-step protein purification processes |
| GB0606144D0 (en) * | 2006-03-28 | 2006-05-10 | Ge Healthcare Bio Sciences Ab | Automated crossflow filtration method and system |
| KR101685246B1 (ko) * | 2006-07-14 | 2016-12-09 | 디피엑스 홀딩스 비.브이. | 개선된 세포 배양 방법 |
| FR2925923B1 (fr) * | 2007-12-28 | 2009-12-18 | Michelin Soc Tech | Procede et dispositif de fabrication d'un cable a deux couches du type gomme in situ |
| JP5003614B2 (ja) * | 2008-07-03 | 2012-08-15 | 株式会社日立プラントテクノロジー | 生体細胞の分離方法及び培養装置 |
| US9446354B2 (en) * | 2010-08-25 | 2016-09-20 | Repligen Corporation | Device, system and process for modification or concentration of cell-depleted fluid |
| US9550969B2 (en) * | 2011-03-18 | 2017-01-24 | Ge Healthcare Bio-Sciences Ab | Flexible bag for cultivation of cells |
| CA2861270C (en) * | 2012-01-18 | 2021-08-03 | Bayer Healthcare Llc | Perfusion bioreactor systems comprising a cell aggregate trap and methods of operating the same |
| SG11201404611RA (en) * | 2012-02-20 | 2014-09-26 | Bayer Technology Services Gmbh | One-way separator for retaining and recirculating cells |
| EP2900804B1 (en) * | 2012-09-27 | 2019-09-18 | GE Healthcare Bio-Sciences AB | Tangential flow perfusion system |
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2014
- 2014-09-16 BR BR112016005545-4A patent/BR112016005545B1/pt active IP Right Grant
- 2014-09-16 EA EA201690602A patent/EA031652B1/ru not_active IP Right Cessation
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