MX2016003440A - Metodos y sistemas para el procesamiento de un cultivo celular. - Google Patents

Metodos y sistemas para el procesamiento de un cultivo celular.

Info

Publication number
MX2016003440A
MX2016003440A MX2016003440A MX2016003440A MX2016003440A MX 2016003440 A MX2016003440 A MX 2016003440A MX 2016003440 A MX2016003440 A MX 2016003440A MX 2016003440 A MX2016003440 A MX 2016003440A MX 2016003440 A MX2016003440 A MX 2016003440A
Authority
MX
Mexico
Prior art keywords
cell culture
methods
processing
systems
filtration
Prior art date
Application number
MX2016003440A
Other languages
English (en)
Inventor
Konstantinov Konstantin
Zhou Hang
Wright Benjamin
Yu Marcella
Yin Jin
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51660627&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016003440(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of MX2016003440A publication Critical patent/MX2016003440A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Water Supply & Treatment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

En la presente memoria se proporcionan métodos de procesamiento de un cultivo celular y sistemas de filtración de circuito abierto. Los sistemas de filtración comprenden una unidad de filtración de flujo tangencial (TFF) que tiene puertas de entrada y salida indpendientes conectadas al biorreactor de cultivo de células y una bomba destinada a invertir el flujo de fluido a través de la unidad de filtración.
MX2016003440A 2013-09-16 2014-09-16 Metodos y sistemas para el procesamiento de un cultivo celular. MX2016003440A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361878502P 2013-09-16 2013-09-16
PCT/US2014/055897 WO2015039115A1 (en) 2013-09-16 2014-09-16 Methods and systems for processing a cell culture

Publications (1)

Publication Number Publication Date
MX2016003440A true MX2016003440A (es) 2016-11-11

Family

ID=51660627

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016003440A MX2016003440A (es) 2013-09-16 2014-09-16 Metodos y sistemas para el procesamiento de un cultivo celular.
MX2021007792A MX2021007792A (es) 2013-09-16 2016-03-16 Metodos y sistemas para el procesamiento de un cultivo celular.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021007792A MX2021007792A (es) 2013-09-16 2016-03-16 Metodos y sistemas para el procesamiento de un cultivo celular.

Country Status (18)

Country Link
US (2) US20150158907A1 (es)
EP (1) EP3047013B1 (es)
JP (4) JP6925127B2 (es)
KR (3) KR20230142653A (es)
CN (2) CN113444620B (es)
AU (4) AU2014318420B2 (es)
BR (2) BR112016005545B1 (es)
CA (1) CA2924332C (es)
CY (1) CY1124684T1 (es)
DK (1) DK3047013T3 (es)
EA (2) EA031652B1 (es)
ES (1) ES2891728T3 (es)
HK (1) HK1222672A1 (es)
HU (1) HUE055888T2 (es)
IL (1) IL244552B (es)
MX (2) MX2016003440A (es)
SG (2) SG10201803601SA (es)
WO (1) WO2015039115A1 (es)

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Publication number Publication date
WO2015039115A1 (en) 2015-03-19
BR122021001466B1 (pt) 2021-10-13
US20150158907A1 (en) 2015-06-11
AU2020202568A1 (en) 2020-05-07
JP2020124204A (ja) 2020-08-20
JP6925127B2 (ja) 2021-08-25
JP2023058588A (ja) 2023-04-25
CA2924332C (en) 2023-03-14
CN113444620B (zh) 2024-03-29
EA201690602A1 (ru) 2016-07-29
EP3047013A1 (en) 2016-07-27
BR112016005545B1 (pt) 2021-06-01
KR102369211B1 (ko) 2022-03-03
AU2014318420A1 (en) 2016-04-14
KR20220031937A (ko) 2022-03-14
AU2020202568B2 (en) 2022-06-02
CY1124684T1 (el) 2022-07-22
SG10201803601SA (en) 2018-06-28
US20210269477A1 (en) 2021-09-02
KR20230142653A (ko) 2023-10-11
JP7227406B2 (ja) 2023-02-21
ES2891728T3 (es) 2022-01-31
EP3047013B1 (en) 2021-08-18
CN105722967B (zh) 2021-03-19
SG11201601899TA (en) 2016-04-28
EA031652B1 (ru) 2019-02-28
CN113444620A (zh) 2021-09-28
DK3047013T3 (da) 2021-11-15
MX2021007792A (es) 2021-08-11
HK1222672A1 (zh) 2017-07-07
CA2924332A1 (en) 2015-03-19
JP2022050549A (ja) 2022-03-30
CN105722967A (zh) 2016-06-29
IL244552A0 (en) 2016-04-21
AU2024219335A1 (en) 2024-09-19
AU2014318420B2 (en) 2020-01-16
EA035665B1 (ru) 2020-07-23
JP2016530893A (ja) 2016-10-06
EA201892084A1 (ru) 2019-02-28
HUE055888T2 (hu) 2022-01-28
IL244552B (en) 2020-04-30
AU2022221495A1 (en) 2022-09-22
KR20160055866A (ko) 2016-05-18
JP7008746B2 (ja) 2022-01-25

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