JP6896628B2 - 細菌感染症の治療のための抗微生物性ポリミキシン - Google Patents

細菌感染症の治療のための抗微生物性ポリミキシン Download PDF

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JP6896628B2
JP6896628B2 JP2017532053A JP2017532053A JP6896628B2 JP 6896628 B2 JP6896628 B2 JP 6896628B2 JP 2017532053 A JP2017532053 A JP 2017532053A JP 2017532053 A JP2017532053 A JP 2017532053A JP 6896628 B2 JP6896628 B2 JP 6896628B2
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JP2018502845A (ja
JP2018502845A5 (https=
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フェドロビッチ ゴルデエフ ミハイル
フェドロビッチ ゴルデエフ ミハイル
リウ ジンキアン
リウ ジンキアン
ワング ジングハイ
ワング ジングハイ
ユアン ズヘンギュ
ユアン ズヘンギュ
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シャンハイ ミクウルク ファーマシューティカル シーオー．エルティーディー
シャンハイ ミクウルク ファーマシューティカル シーオー．エルティーディー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
JP2017532053A 2014-12-16 2015-12-16 細菌感染症の治療のための抗微生物性ポリミキシン Active JP6896628B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462092780P 2014-12-16 2014-12-16
US62/092,780 2014-12-16
PCT/US2015/066210 WO2016100578A2 (en) 2014-12-16 2015-12-16 Antimicrobial polymyxins for treatment of bacterial infections

Publications (3)

Publication Number Publication Date
JP2018502845A JP2018502845A (ja) 2018-02-01
JP2018502845A5 JP2018502845A5 (https=) 2019-02-28
JP6896628B2 true JP6896628B2 (ja) 2021-06-30

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JP2017532053A Active JP6896628B2 (ja) 2014-12-16 2015-12-16 細菌感染症の治療のための抗微生物性ポリミキシン

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Country Link
US (1) US9771394B2 (https=)
EP (1) EP3233889B1 (https=)
JP (1) JP6896628B2 (https=)
KR (1) KR102585108B1 (https=)
CN (1) CN107257803B (https=)
CA (1) CA2970546A1 (https=)
ES (1) ES2924058T3 (https=)
WO (1) WO2016100578A2 (https=)

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CN111527100A (zh) 2017-11-02 2020-08-11 昆士兰大学 肽类抗生素
WO2019237186A1 (en) * 2018-06-12 2019-12-19 University Of Manitoba Preparation of dilipid polymyxins and use thereof as antimicrobial adjuvants
CN111690040A (zh) * 2019-03-12 2020-09-22 上海来益生物药物研究开发中心有限责任公司 多粘菌素衍生物、其制备方法和应用
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CN112300247B (zh) * 2019-07-24 2022-12-27 广东东阳光药业有限公司 一种Teixobactin类似物及其用途
JP7045520B2 (ja) * 2020-01-02 2022-03-31 上海上薬第一生化薬業有限公司 ポリミキシンｂ成分又はその塩、その製造方法及び使用
WO2021150792A1 (en) 2020-01-21 2021-07-29 Micurx Pharmaceuticals, Inc. Novel compounds and composition for targeted therapy of kidney-associated cancers
JP7755347B2 (ja) * 2021-07-21 2025-10-16 シャンハイ ミクウルク ファーマシューティカル シーオー．エルティーディー 腎癌の標的治療のための新規化合物及び組成物
US20250109171A1 (en) * 2021-07-21 2025-04-03 Shanghai MICURX Pharmaceuticals Co., Ltd. Compounds and compositions for targeted therapy of renal diseases

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JPS5831918B2 (ja) 1976-10-27 1983-07-09 塩野義製薬株式会社 新規抗生物質ポリミキシンｓ↓１
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JP2018502845A (ja) 2018-02-01
KR20170086671A (ko) 2017-07-26
CN107257803B (zh) 2021-02-05
WO2016100578A2 (en) 2016-06-23
KR102585108B1 (ko) 2023-10-05
US20160185823A1 (en) 2016-06-30
EP3233889A2 (en) 2017-10-25
EP3233889B1 (en) 2022-07-06
ES2924058T3 (es) 2022-10-04
WO2016100578A3 (en) 2016-08-11
CN107257803A (zh) 2017-10-17
CA2970546A1 (en) 2016-06-23
US9771394B2 (en) 2017-09-26

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