JP6836905B2 - 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用 - Google Patents

尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用 Download PDF

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JP6836905B2
JP6836905B2 JP2016565117A JP2016565117A JP6836905B2 JP 6836905 B2 JP6836905 B2 JP 6836905B2 JP 2016565117 A JP2016565117 A JP 2016565117A JP 2016565117 A JP2016565117 A JP 2016565117A JP 6836905 B2 JP6836905 B2 JP 6836905B2
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JP2017505811A (ja
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パハン，カリパダ
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ラッシュ・ユニバーシティ・メディカル・センター
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2016565117A 2014-01-17 2015-01-16 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用 Active JP6836905B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461928622P 2014-01-17 2014-01-17
US61/928,622 2014-01-17
PCT/US2015/011798 WO2015109215A1 (en) 2014-01-17 2015-01-16 The use of a benzoate containing composition in urea cycle disorders and neurodegenerativre disordrs

Related Child Applications (1)

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JP2019191224A Division JP2020037558A (ja) 2014-01-17 2019-10-18 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用

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JP2017505811A JP2017505811A (ja) 2017-02-23
JP2017505811A5 JP2017505811A5 (https=) 2018-02-22
JP6836905B2 true JP6836905B2 (ja) 2021-03-03

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JP2016565117A Active JP6836905B2 (ja) 2014-01-17 2015-01-16 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用
JP2019191224A Pending JP2020037558A (ja) 2014-01-17 2019-10-18 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用

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JP2019191224A Pending JP2020037558A (ja) 2014-01-17 2019-10-18 尿素サイクル障害及び神経変性障害におけるベンゾエート含有組成物の使用

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US (1) US9968582B2 (https=)
EP (1) EP3094616B1 (https=)
JP (2) JP6836905B2 (https=)
CA (1) CA2936548C (https=)
CY (1) CY1124115T1 (https=)
DK (1) DK3094616T3 (https=)
ES (1) ES2853974T3 (https=)
HR (1) HRP20210361T1 (https=)
HU (1) HUE053671T2 (https=)
LT (1) LT3094616T (https=)
PL (1) PL3094616T3 (https=)
PT (1) PT3094616T (https=)
RS (1) RS61611B1 (https=)
SI (1) SI3094616T1 (https=)
SM (1) SMT202100074T1 (https=)
WO (1) WO2015109215A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202090666A1 (ru) * 2017-10-06 2020-08-05 Раш Юниверсити Медикал Сентер Применение содержащей бензоат композиции для лечения глициновой энцефалопатии
JP7034314B2 (ja) * 2017-11-22 2022-03-11 潔欣 林 うつ病を予防または治療するための安息香酸またはその塩および誘導体
US12478598B2 (en) 2019-02-25 2025-11-25 Rush University Medical Center Compositions including cinnamic acid and methods of use thereof
CN114502154A (zh) * 2019-07-16 2022-05-13 拉什大学医学中心 含苯甲酸酯的组合物治疗神经退行性疾病的用途
CN116390761A (zh) * 2020-10-28 2023-07-04 拉什大学医学中心 肉桂酸苄酯组合物在治疗甘氨酸脑病和尿素循环障碍中的应用
CA3205005A1 (en) * 2020-12-16 2022-06-23 Rush University Medical Center Administration of glycerol tribenzoate and glycerol phenylbutyrate for treatment of neurodegenerative and urea cycle disorders
JP2025503457A (ja) * 2021-12-16 2025-02-04 ザ ユナイテッド ステイツ ガバメント アズ リプレゼンティド バイ ザ デパートメント オブ ヴェテランズ アフェアーズ 神経系損傷及び障害の治療のための安息香酸塩

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284647A (en) * 1980-03-31 1981-08-18 The Johns Hopkins University Process for waste nitrogen removal
WO2008083226A2 (en) 2006-12-28 2008-07-10 Navinta Llc Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate

Also Published As

Publication number Publication date
CY1124115T1 (el) 2022-05-27
EP3094616B1 (en) 2020-12-23
US9968582B2 (en) 2018-05-15
ES2853974T3 (es) 2021-09-20
SI3094616T1 (sl) 2021-07-30
JP2017505811A (ja) 2017-02-23
SMT202100074T1 (it) 2021-05-07
CA2936548A1 (en) 2015-07-23
US20160331714A1 (en) 2016-11-17
EP3094616A1 (en) 2016-11-23
HRP20210361T1 (hr) 2021-04-16
RS61611B1 (sr) 2021-04-29
CA2936548C (en) 2022-08-30
JP2020037558A (ja) 2020-03-12
HUE053671T2 (hu) 2021-07-28
LT3094616T (lt) 2021-04-12
PL3094616T3 (pl) 2021-05-31
WO2015109215A1 (en) 2015-07-23
EP3094616A4 (en) 2017-08-23
PT3094616T (pt) 2021-03-03
DK3094616T3 (da) 2021-02-15

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