JP6835586B2 - マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法 - Google Patents

マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法 Download PDF

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JP6835586B2
JP6835586B2 JP2016549123A JP2016549123A JP6835586B2 JP 6835586 B2 JP6835586 B2 JP 6835586B2 JP 2016549123 A JP2016549123 A JP 2016549123A JP 2016549123 A JP2016549123 A JP 2016549123A JP 6835586 B2 JP6835586 B2 JP 6835586B2
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JP2017509594A5 (enExample
JP2017509594A (ja
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ジェイムズ ムーア スティーブン
ジェイムズ ムーア スティーブン
ティー ルー グエン マーガレット
ティー ルー グエン マーガレット
アール．ホステッター ダニエル
アール．ホステッター ダニエル
バジルジェバ オルガ
バジルジェバ オルガ
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シトムクス セラピューティクス，インコーポレイティド
シトムクス セラピューティクス，インコーポレイティド
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C—CHEMISTRY; METALLURGY
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JP2016549123A 2014-01-31 2015-01-30 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法 Active JP6835586B2 (ja)

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JP2021016630A JP7337864B2 (ja) 2014-01-31 2021-02-04 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法
JP2023134791A JP7819160B2 (ja) 2014-01-31 2023-08-22 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法
JP2025161356A JP2026004397A (ja) 2014-01-31 2025-09-29 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法

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US201461934619P 2014-01-31 2014-01-31
US61/934,619 2014-01-31
US201461971009P 2014-03-27 2014-03-27
US61/971,009 2014-03-27
PCT/US2015/013776 WO2015116933A2 (en) 2014-01-31 2015-01-30 Matriptase and u-plasminogen activator substrates and other cleavable moieties and methods of use thereof

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JP2017509594A5 JP2017509594A5 (enExample) 2018-03-08
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JP2021016630A Active JP7337864B2 (ja) 2014-01-31 2021-02-04 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法
JP2023134791A Active JP7819160B2 (ja) 2014-01-31 2023-08-22 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法
JP2025161356A Pending JP2026004397A (ja) 2014-01-31 2025-09-29 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法

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JP2023134791A Active JP7819160B2 (ja) 2014-01-31 2023-08-22 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法
JP2025161356A Pending JP2026004397A (ja) 2014-01-31 2025-09-29 マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法

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Cited By (1)

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JP2021072848A (ja) * 2014-01-31 2021-05-13 シトムクス セラピューティクス，インコーポレイティド マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法

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GB201203442D0 (en) 2012-02-28 2012-04-11 Univ Birmingham Immunotherapeutic molecules and uses
CN105722859B (zh) * 2013-07-25 2021-05-07 西托姆克斯治疗公司 多特异性抗体、多特异性可活化抗体及其使用方法
NZ718283A (en) 2013-09-25 2022-05-27 Cytomx Therapeutics Inc Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof
CA2955947A1 (en) 2014-07-25 2016-01-28 Cytomx Therapeutics, Inc. Anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable anti-cd3 antibodies, and methods of using the same
MA41374A (fr) 2015-01-20 2017-11-28 Cytomx Therapeutics Inc Substrats clivables par métalloprotéase matricielle et clivables par sérine protéase et procédés d'utilisation de ceux-ci
EP3296395B2 (en) 2015-05-13 2024-06-19 Chugai Seiyaku Kabushiki Kaisha Multiple antigen binding molecular fusion, pharmaceutical composition, method for identifying linear epitope, and method for preparing multiple antigen binding molecular fusion
EA034582B1 (ru) * 2015-08-07 2020-02-21 АЭлЭкс ОНКОЛОДЖИ ИНК. Конструкции варианта sirp-альфа и их применение
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IL302642B2 (en) 2025-04-01
AU2015210862A1 (en) 2016-08-11
EP4176896B1 (en) 2025-10-08
US9562073B2 (en) 2017-02-07
CN106459153A (zh) 2017-02-22
WO2015116933A3 (en) 2015-10-08
US20190135864A1 (en) 2019-05-09
RU2016135239A3 (enExample) 2019-01-17
IL294782A (en) 2022-09-01
RU2016135239A (ru) 2018-03-12
NZ722401A (en) 2023-06-30
AU2023278068A1 (en) 2024-01-04
CN106459153B (zh) 2021-12-21
EP3628328A1 (en) 2020-04-01
IL302642A (en) 2023-07-01
JP7819160B2 (ja) 2026-02-24
IL317045A (en) 2025-01-01
AU2020205249B2 (en) 2023-09-07
US20150218217A1 (en) 2015-08-06
BR112016017649B1 (pt) 2024-01-30
IL246988A0 (en) 2016-09-29
JP2017509594A (ja) 2017-04-06
IL294782B1 (en) 2023-06-01
IL270562B (en) 2022-08-01
IL294782B2 (en) 2023-10-01
EP4176896A1 (en) 2023-05-10
ES2932777T3 (es) 2023-01-25
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CA2937370A1 (en) 2015-08-06
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US20220411470A1 (en) 2022-12-29
AU2015210862B2 (en) 2020-04-23
CN114106099B (zh) 2024-05-24
BR122023022856A2 (pt) 2023-12-12
JP2021072848A (ja) 2021-05-13
JP7337864B2 (ja) 2023-09-04
IL270562A (enExample) 2020-01-30
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