JP6790963B2 - 液体クロマトグラフ - Google Patents

液体クロマトグラフ Download PDF

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Publication number
JP6790963B2
JP6790963B2 JP2017068461A JP2017068461A JP6790963B2 JP 6790963 B2 JP6790963 B2 JP 6790963B2 JP 2017068461 A JP2017068461 A JP 2017068461A JP 2017068461 A JP2017068461 A JP 2017068461A JP 6790963 B2 JP6790963 B2 JP 6790963B2
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Japan
Prior art keywords
flow path
measurement
sample
columns
column
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Japanese (ja)
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JP2018169350A5 (enExample
JP2018169350A (ja
Inventor
研壱 保永
研壱 保永
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Shimadzu Corp
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Shimadzu Corp
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Priority to JP2017068461A priority Critical patent/JP6790963B2/ja
Priority to US15/936,529 priority patent/US10866217B2/en
Publication of JP2018169350A publication Critical patent/JP2018169350A/ja
Publication of JP2018169350A5 publication Critical patent/JP2018169350A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G01N2030/201—Injection using a sampling valve multiport valves, i.e. having more than two ports
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/324—Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N2030/628—Multiplexing, i.e. several columns sharing a single detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2017068461A 2017-03-30 2017-03-30 液体クロマトグラフ Active JP6790963B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2017068461A JP6790963B2 (ja) 2017-03-30 2017-03-30 液体クロマトグラフ
US15/936,529 US10866217B2 (en) 2017-03-30 2018-03-27 Liquid chromatograph flow path switching and control system for columns to a detector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2017068461A JP6790963B2 (ja) 2017-03-30 2017-03-30 液体クロマトグラフ

Publications (3)

Publication Number Publication Date
JP2018169350A JP2018169350A (ja) 2018-11-01
JP2018169350A5 JP2018169350A5 (enExample) 2019-08-15
JP6790963B2 true JP6790963B2 (ja) 2020-11-25

Family

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JP2017068461A Active JP6790963B2 (ja) 2017-03-30 2017-03-30 液体クロマトグラフ

Country Status (2)

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US (1) US10866217B2 (enExample)
JP (1) JP6790963B2 (enExample)

Families Citing this family (14)

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US11988648B2 (en) * 2017-12-04 2024-05-21 Shimadzu Corporation Liquid chromatograph
WO2019157297A1 (en) * 2018-02-08 2019-08-15 Wiederin Daniel R Inline dilution and autocalibration for icp-ms speciation analysis
US11567044B2 (en) * 2018-09-21 2023-01-31 Hitachi High-Tech Corporation Analysis device having a liquid chromatograph and method for analyzing a liquid chromatograph
CN112888941B (zh) * 2018-10-26 2024-11-12 安捷伦科技有限公司 用于多维样品分离设备的注入器
JPWO2020105661A1 (ja) * 2018-11-20 2021-09-30 株式会社日立ハイテク 複数のクロマトグラフを有する分析装置及びその制御方法
CN113474647B (zh) 2019-03-13 2024-01-23 株式会社岛津制作所 色谱仪用自动进样器
WO2020194606A1 (ja) * 2019-03-27 2020-10-01 株式会社島津製作所 クロマトグラフ装置および分析方法
WO2021166265A1 (ja) * 2020-02-21 2021-08-26 株式会社島津製作所 液体クロマトグラフ
JP7342741B2 (ja) 2020-03-11 2023-09-12 株式会社島津製作所 試料注入装置、および、液体クロマトグラフ
US12306148B2 (en) 2020-11-05 2025-05-20 Shimadzu Corporation Analysis system and analysis execution method
JP7600865B2 (ja) * 2020-11-05 2024-12-17 株式会社島津製作所 分析システムおよび分析方法
DE102020133422A1 (de) * 2020-12-14 2022-06-15 Agilent Technologies, Inc. - A Delaware Corporation - Montagevorrichtung zum Montieren einer Probentrenneinrichtung
US12216100B2 (en) * 2021-12-09 2025-02-04 Shimadzu Corporation Method for separating odorous compound and supercritical fluid chromatograph
WO2024219149A1 (ja) * 2023-04-17 2024-10-24 株式会社島津製作所 液体クロマトグラフシステムおよび制御方法

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US6720190B1 (en) * 1998-03-27 2004-04-13 Ole Hindsgaul Methods for screening compound libraries
AU2986400A (en) * 1999-02-08 2000-08-25 Admetric Biochem Inc. Chromatographic system with pre-detector eluent switching
US6296771B1 (en) * 1999-04-02 2001-10-02 Symyx Technologies, Inc. Parallel high-performance liquid chromatography with serial injection
US6318157B1 (en) * 1999-04-23 2001-11-20 Advanced Bioanalytical Services, Inc. High-throughput parallel liquid chromatography system
WO2001088528A2 (en) * 2000-05-12 2001-11-22 Admetric Biochem Inc. High throughput chromatographic systems
US6802967B2 (en) * 2002-03-06 2004-10-12 Shimadzu Corporation Multi-dimension liquid chromatography separation system
US20030172724A1 (en) * 2002-03-15 2003-09-18 Symyx Technologies, Inc. Liquid chromatography column distributor
DE112004000997B4 (de) * 2003-06-06 2018-04-12 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Vorrichtung und Verfahren zum Durchführen paralleler Prozesse
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JP2006125856A (ja) * 2004-10-26 2006-05-18 Sumitomo Chemical Co Ltd 液体クロマトグラフィー装置
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JP5637313B2 (ja) * 2011-07-15 2014-12-10 株式会社島津製作所 液体クロマトグラフ用制御装置及びプログラム
CN102879508B (zh) * 2011-07-15 2014-12-03 株式会社岛津制作所 用于液相色谱仪的控制设备
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JP2013200231A (ja) * 2012-03-26 2013-10-03 Toppan Printing Co Ltd 複数の流路を持つクロマトグラフ分析装置
WO2015094094A1 (en) * 2013-12-19 2015-06-25 Ge Healthcare Bio-Sciences Ab A chromatography system and method
JP6203557B2 (ja) * 2013-07-05 2017-09-27 株式会社日立製作所 分離装置及び分離方法
JP6127790B2 (ja) * 2013-07-12 2017-05-17 株式会社島津製作所 液体クロマトグラフ用制御装置および制御方法
CN105980847B (zh) * 2014-02-14 2018-12-04 通用电气健康护理生物科学股份公司 自动多步纯化系统
JP6260351B2 (ja) * 2014-03-04 2018-01-17 株式会社島津製作所 クロマトグラフ用データ処理装置及びデータ処理方法
JP6331485B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ及び液体クロマトグラフ分析方法
JP6331484B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ制御装置及び液体クロマトグラフ制御方法

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Publication number Publication date
JP2018169350A (ja) 2018-11-01
US20180284079A1 (en) 2018-10-04
US10866217B2 (en) 2020-12-15

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