JP6738808B2 - ヒト心室前駆体細胞を単離するための細胞表面マーカーとしてのＪａｇｇｅｄ１／Ｆｒｉｚｚｌｅｄ４の使用 - Google Patents

ヒト心室前駆体細胞を単離するための細胞表面マーカーとしてのＪａｇｇｅｄ１／Ｆｒｉｚｚｌｅｄ４の使用 Download PDF

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JP6738808B2
JP6738808B2 JP2017529972A JP2017529972A JP6738808B2 JP 6738808 B2 JP6738808 B2 JP 6738808B2 JP 2017529972 A JP2017529972 A JP 2017529972A JP 2017529972 A JP2017529972 A JP 2017529972A JP 6738808 B2 JP6738808 B2 JP 6738808B2
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ケネス アール． チェン，
ケネス アール． チェン，
シャオジュン リアン，
シャオジュン リアン，
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プロセラ セラピューティクス アーベー
プロセラ セラピューティクス アーベー
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/415—Wnt; Frizzeled
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2017529972A 2014-08-22 2015-08-21 ヒト心室前駆体細胞を単離するための細胞表面マーカーとしてのＪａｇｇｅｄ１／Ｆｒｉｚｚｌｅｄ４の使用 Active JP6738808B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462040892P 2014-08-22 2014-08-22
US62/040,892 2014-08-22
US201562194016P 2015-07-17 2015-07-17
US62/194,016 2015-07-17
PCT/US2015/046309 WO2016029122A1 (en) 2014-08-22 2015-08-21 Use of jagged 1/frizzled 4 as a cell surface marker for isolating human cardiac ventricular progenitor cells

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JP2020076020A Division JP2020120677A (ja) 2014-08-22 2020-04-22 ヒト心室前駆体細胞を単離するための細胞表面マーカーとしてのＪａｇｇｅｄ１／Ｆｒｉｚｚｌｅｄ４の使用

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JP2017525393A JP2017525393A (ja) 2017-09-07
JP2017525393A5 JP2017525393A5 (https=) 2018-08-02
JP6738808B2 true JP6738808B2 (ja) 2020-08-12

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JP2020076020A Pending JP2020120677A (ja) 2014-08-22 2020-04-22 ヒト心室前駆体細胞を単離するための細胞表面マーカーとしてのＪａｇｇｅｄ１／Ｆｒｉｚｚｌｅｄ４の使用

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US (1) US10597637B2 (https=)
EP (2) EP3183337B1 (https=)
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DK (1) DK3183337T3 (https=)
MA (1) MA40589A (https=)
WO (1) WO2016029122A1 (https=)

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US10596200B2 (en) 2014-08-22 2020-03-24 Procella Therapeutics Ab Use of LIFR or FGFR3 as a cell surface marker for isolating human cardiac ventricular progenitor cells
DK3417073T3 (da) * 2016-02-19 2023-10-30 Procella Therapeutics Ab Genetiske markører til transplantation af humane, hjerteventrikulære progenitorceller
US20190136191A1 (en) * 2016-05-02 2019-05-09 Emory University Methods of Producing Specialized Cardio-Like Cells from Stem Cells
EP3519559A1 (en) * 2016-09-30 2019-08-07 Wisconsin Alumini Research Foundation Primed cardiac progenitors and methods for making and using same
US10508263B2 (en) * 2016-11-29 2019-12-17 Procella Therapeutics Ab Methods for isolating human cardiac ventricular progenitor cells
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
WO2019038587A1 (en) 2017-08-23 2019-02-28 Procella Therapeutics Ab USE OF NEUROPILIN-1 (NRP1) AS A CELL SURFACE MARKER FOR ISOLATING HUMAN CARDIAC VENTRICULAR PROGENITOR CELLS
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DK3417073T3 (da) 2016-02-19 2023-10-30 Procella Therapeutics Ab Genetiske markører til transplantation af humane, hjerteventrikulære progenitorceller
US10508263B2 (en) 2016-11-29 2019-12-17 Procella Therapeutics Ab Methods for isolating human cardiac ventricular progenitor cells

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Publication number Publication date
US10597637B2 (en) 2020-03-24
EP3183337B1 (en) 2019-02-06
MA40589A (fr) 2017-06-28
WO2016029122A1 (en) 2016-02-25
JP2020120677A (ja) 2020-08-13
EP3183337A1 (en) 2017-06-28
JP2017525393A (ja) 2017-09-07
US20160053229A1 (en) 2016-02-25
EP3524673A1 (en) 2019-08-14
DK3183337T3 (en) 2019-04-01

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