JP6686008B2 - がん特異的突然変異に対し抗原特異性を有するｔ細胞受容体を単離する方法 - Google Patents

がん特異的突然変異に対し抗原特異性を有するｔ細胞受容体を単離する方法 Download PDF

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JP6686008B2
JP6686008B2 JP2017517662A JP2017517662A JP6686008B2 JP 6686008 B2 JP6686008 B2 JP 6686008B2 JP 2017517662 A JP2017517662 A JP 2017517662A JP 2017517662 A JP2017517662 A JP 2017517662A JP 6686008 B2 JP6686008 B2 JP 6686008B2
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cells
amino acid
acid sequence
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tcr
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JP2017531640A5 (enExample
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トラン、エリック
ル、ヨング−チェン
エフ． ロビンズ、ポール
エフ． ロビンズ、ポール
エー． ロゼンバーグ、ステーヴン
エー． ロゼンバーグ、ステーヴン
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JP2017517662A 2014-10-02 2014-10-02 がん特異的突然変異に対し抗原特異性を有するｔ細胞受容体を単離する方法 Active JP6686008B2 (ja)

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PCT/US2014/058796 WO2016053338A1 (en) 2014-10-02 2014-10-02 Methods of isolating t cell receptors having antigenic specificity for a cancer-specific mutation

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JP2020066108A Division JP2020143057A (ja) 2020-04-01 2020-04-01 がん特異的突然変異に対し抗原特異性を有するｔ細胞受容体を単離する方法

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JP2017531640A JP2017531640A (ja) 2017-10-26
JP2017531640A5 JP2017531640A5 (enExample) 2017-12-07
JP6686008B2 true JP6686008B2 (ja) 2020-04-22

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US (2) US20170218042A1 (enExample)
EP (2) EP4074333A1 (enExample)
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CN (2) CN107074932A (enExample)
AU (3) AU2014407539B2 (enExample)
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Families Citing this family (76)

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US20170044496A1 (en) 2014-04-10 2017-02-16 H. Lee Moffitt Cancer Center And Research Institute, Inc. Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy
US10973894B2 (en) 2014-10-02 2021-04-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Methods of isolating T cells having antigenic specificity for a cancer-specific mutation
EP3075389A1 (en) * 2015-03-31 2016-10-05 Technische Universität München T cell receptors and peptides derived by mutations for the treatment of cancer
WO2016179006A1 (en) 2015-05-01 2016-11-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of isolating t cells and t cell receptors having antigenic specificity for a cancer-specific mutation from peripheral blood
GB2557123B (en) 2015-07-31 2021-11-03 Univ Minnesota Modified cells and methods of therapy
WO2017048614A1 (en) 2015-09-15 2017-03-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of isolating tumor-reactive t cell receptors from tumor or peripheral blood
MX2019000149A (es) 2016-07-07 2019-09-23 Iovance Biotherapeutics Inc Proteinas de union a ligando 1 de muerte programada 1 (pd-l1) y metodos de uso de las mismas.
GB2573406B (en) 2016-10-18 2021-11-10 Univ Minnesota Tumor infiltrating lymphocytes and methods of therapy
PL3532607T3 (pl) 2016-10-26 2024-07-01 Iovance Biotherapeutics, Inc. Restymulacja kriokonserwowanych limfocytów naciekających guza nowotworowego
TWI788307B (zh) 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
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